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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50316437'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (human))
BDBM50316437
PNG
((6R,12aR)-6-(2-Bromophenyl)-2-butyl-2,3,6,7,12,12a...)
Show SMILES CCCCN1CC(=O)N2[C@H](Cc3c([nH]c4ccccc34)[C@H]2c2ccccc2Br)C1=O
Show InChI InChI=1S/C24H24BrN3O2/c1-2-3-12-27-14-21(29)28-20(24(27)30)13-17-15-8-5-7-11-19(15)26-22(17)23(28)16-9-4-6-10-18(16)25/h4-11,20,23,26H,2-3,12-14H2,1H3/t20-,23-/m1/s1
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Similars

Article
PubMed
n/an/a 260n/an/an/an/an/an/a



German University in Cairo

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE5 after 1.5 hrs by fluorescent polarization assay


Eur J Med Chem 45: 1278-86 (2010)


Article DOI: 10.1016/j.ejmech.2009.10.046
BindingDB Entry DOI: 10.7270/Q26W9B6P
More data for this
Ligand-Target Pair