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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'hdgat le' and Ligand = 'BDBM321139'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
hdgat le


(Homo sapiens (Human))
BDBM321139
PNG
(US10174049, Example 6 | US9738658, Example 6)
Show SMILES COc1cc(ccc1-n1ccc2cc(ccc12)N1CCOc2ncnc(N)c2C1=O)C(F)(F)F
Show InChI InChI=1S/C23H18F3N5O3/c1-33-18-11-14(23(24,25)26)2-4-17(18)31-7-6-13-10-15(3-5-16(13)31)30-8-9-34-21-19(22(30)32)20(27)28-12-29-21/h2-7,10-12H,8-9H2,1H3,(H2,27,28,29)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 25n/an/an/an/an/an/a



GlaxoSmithKline LLC

US Patent


Assay Description
For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...


US Patent US9738658 (2017)

More data for this
Ligand-Target Pair