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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'hdgat le' and Ligand = 'BDBM321152'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
hdgat le


(Homo sapiens (Human))
BDBM321152
PNG
(US10174049, Example 19 | US9738658, Example 19)
Show SMILES Nc1ncnc2OCCN(c3cnc4n(ccc4c3)-c3ccccc3OC3CCCC3)C(=O)c12
Show InChI InChI=1S/C25H24N6O3/c26-22-21-24(29-15-28-22)33-12-11-30(25(21)32)17-13-16-9-10-31(23(16)27-14-17)19-7-3-4-8-20(19)34-18-5-1-2-6-18/h3-4,7-10,13-15,18H,1-2,5-6,11-12H2,(H2,26,28,29)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 11.2n/an/an/an/an/an/a



GlaxoSmithKline LLC

US Patent


Assay Description
For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...


US Patent US9738658 (2017)

More data for this
Ligand-Target Pair