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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'hdgat le' and Ligand = 'BDBM321158'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
hdgat le


(Homo sapiens (Human))
BDBM321158
PNG
(US10174049, Example 25 | US9738658, Example 25)
Show SMILES CC(C)n1ccc2cc(cc(NC(=O)C3CC3)c12)N1CCOc2ncnc(N)c2C1=O
Show InChI InChI=1S/C22H24N6O3/c1-12(2)27-6-5-14-9-15(10-16(18(14)27)26-20(29)13-3-4-13)28-7-8-31-21-17(22(28)30)19(23)24-11-25-21/h5-6,9-13H,3-4,7-8H2,1-2H3,(H,26,29)(H2,23,24,25)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 93n/an/an/an/an/an/a



GlaxoSmithKline LLC

US Patent


Assay Description
For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...


US Patent US9738658 (2017)

More data for this
Ligand-Target Pair