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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'hdgat le' and Ligand = 'BDBM321165'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
hdgat le


(Homo sapiens (Human))
BDBM321165
PNG
(US10174049, Example 32 | US9738658, Example 32)
Show SMILES COc1ncc(cn1)-n1ccc2cc(ccc12)N1CCOc2ncnc(N)c2C1=O
Show InChI InChI=1S/C20H17N7O3/c1-29-20-22-9-14(10-23-20)26-5-4-12-8-13(2-3-15(12)26)27-6-7-30-18-16(19(27)28)17(21)24-11-25-18/h2-5,8-11H,6-7H2,1H3,(H2,21,24,25)
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 38.1n/an/an/an/an/an/a



GlaxoSmithKline LLC

US Patent


Assay Description
For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...


US Patent US9738658 (2017)

More data for this
Ligand-Target Pair