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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'jmjd2a' and Ligand = 'BDBM264045'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
jmjd2a


(Homo sapiens (Human))
BDBM264045
PNG
(2-[5-[(2-chloro-4- methylphenyl)methoxy]pyrazol-1-...)
Show SMILES Cc1ccc(COc2ccnn2-c2cc(ccn2)C(O)=O)c(Cl)c1
Show InChI InChI=1S/C17H14ClN3O3/c1-11-2-3-13(14(18)8-11)10-24-16-5-7-20-21(16)15-9-12(17(22)23)4-6-19-15/h2-9H,10H2,1H3,(H,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...


US Patent US9604961 (2017)

More data for this
Ligand-Target Pair