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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'jmjd2a' and Ligand = 'BDBM264055'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
jmjd2a


(Homo sapiens (Human))
BDBM264055
PNG
(2-[5-[[4-chloro-3- (cyclopropylmethoxy)phenyl] met...)
Show SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccc(Cl)c(OCC2CC2)c1
Show InChI InChI=1S/C20H18ClN3O4/c21-16-4-3-14(9-17(16)27-11-13-1-2-13)12-28-19-6-8-23-24(19)18-10-15(20(25)26)5-7-22-18/h3-10,13H,1-2,11-12H2,(H,25,26)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2A was determined in 384-well plate format under the following reaction conditions: 2 nM...


US Patent US9604961 (2017)

More data for this
Ligand-Target Pair