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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'mknk1 high atp' and Ligand = 'BDBM333380'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
mknk1 high atp


(Homo sapiens (Human))
BDBM333380
PNG
(2-{[3-(1-Benzofuran-2-yl)imidazo[1, 2-b]pyridazin-...)
Show SMILES CCN(CCO)c1ccc2ncc(-c3cc4ccccc4o3)n2n1
Show InChI InChI=1S/C18H18N8O2S/c27-13-9-29-15(14(13)28)12-8-21-18-17(19-4-5-26(12)18)20-7-10-2-1-3-11(6-10)16-22-24-25-23-16/h1-6,8,13-15,27-28H,7,9H2,(H,19,20)(H,22,23,24,25)/t13-,14-,15+/m1/s1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
US Patent
n/an/a 20n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...


US Patent US9730929 (2017)


Article DOI: 10.1016/j.bmcl.2004.10.045
More data for this
Ligand-Target Pair