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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'mknk1 high atp' and Ligand = 'BDBM333381'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
mknk1 high atp


(Homo sapiens (Human))
BDBM333381
PNG
(N-(2-{[3-(1-Benzofuran-2- yl)imidazo[1,2-b]pyridaz...)
Show SMILES CCCN(CCO)c1ccc2ncc(-c3cc4ccccc4o3)n2n1
Show InChI InChI=1S/C18H18F2N4O2S/c19-11-3-1-2-10(14(11)20)4-5-21-17-18-23-8-12(24(18)7-6-22-17)16-15(26)13(25)9-27-16/h1-3,6-8,13,15-16,25-26H,4-5,9H2,(H,21,22)/t13-,15-,16+/m1/s1
PDB
MMDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
US Patent
n/an/a 21n/an/an/an/an/an/a



BAYER INTELLECTUAL PROPERTY GMBH

US Patent


Assay Description
A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...


US Patent US9730929 (2017)


Article DOI: 10.1016/j.bmcl.2004.10.045
More data for this
Ligand-Target Pair