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Compile Data Set for Download or QSAR

Found 1065 hits of Enz. Inhib. data with enzyme = 'Bcl-2-like protein 11' and Substrate = 'to-be-curated'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bcl-2-like protein 11


(Homo sapiens)
BDBM66354
PNG
(2-Phenyl-5-(4-propoxy-phenyl)-3-propyl-tetrahydro-...)
Show SMILES CCCOc1ccc(cc1)-n1c(O)c2ON(C(CCC)c2c1O)c1ccccc1
Show InChI InChI=1S/C23H26N2O4/c1-3-8-19-20-21(29-25(19)17-9-6-5-7-10-17)23(27)24(22(20)26)16-11-13-18(14-12-16)28-15-4-2/h5-7,9-14,19,26-27H,3-4,8,15H2,1-2H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66355
PNG
(Heptanoic acid (4,7-dimethyl-2-oxo-2H-chromen-6-yl...)
Show SMILES CCCCCCC(=O)Nc1cc2c(C)cc(=O)oc2cc1C
Show InChI InChI=1S/C18H23NO3/c1-4-5-6-7-8-17(20)19-15-11-14-12(2)10-18(21)22-16(14)9-13(15)3/h9-11H,4-8H2,1-3H3,(H,19,20)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66356
PNG
(4-[[[(2S)-2-(4-keto-1,2,3-benzotriazin-3-yl)-3-met...)
Show SMILES CCC(C)[C@@H](C(=O)NCC1CCC(CC1)C(O)=O)n1nnc2ccccc2c1=O
Show InChI InChI=1S/C21H28N4O4/c1-3-13(2)18(25-20(27)16-6-4-5-7-17(16)23-24-25)19(26)22-12-14-8-10-15(11-9-14)21(28)29/h4-7,13-15,18H,3,8-12H2,1-2H3,(H,22,26)(H,28,29)/t13?,14?,15?,18-/m0/s1
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66357
PNG
(4-Cyano-5-[2-(3-cyano-4,6-dimethyl-pyridin-2-ylsul...)
Show SMILES CCOC(=O)c1sc(NC(=O)CSc2nc(C)cc(C)c2C#N)c(C#N)c1C
Show InChI InChI=1S/C19H18N4O3S2/c1-5-26-19(25)16-12(4)14(8-21)18(28-16)23-15(24)9-27-17-13(7-20)10(2)6-11(3)22-17/h6H,5,9H2,1-4H3,(H,23,24)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66358
PNG
(2-Oxo-1-oxa-spiro[4.5]decane-4-carboxylic acid phe...)
Show SMILES O=C(Nc1ccccc1)C1CC(=O)OC11CCCCC1
Show InChI InChI=1S/C16H19NO3/c18-14-11-13(16(20-14)9-5-2-6-10-16)15(19)17-12-7-3-1-4-8-12/h1,3-4,7-8,13H,2,5-6,9-11H2,(H,17,19)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM43375
PNG
((2E)-2-(1-cyano-2,2,2-trifluoro-ethylidene)-5-phen...)
Show SMILES CCOC(=O)C1=C(O\C(S1)=C(\C#N)C(F)(F)F)c1ccccc1
Show InChI InChI=1S/C15H10F3NO3S/c1-2-21-13(20)12-11(9-6-4-3-5-7-9)22-14(23-12)10(8-19)15(16,17)18/h3-7H,2H2,1H3/b14-10+
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66359
PNG
((E)-2-cyano-3-(4-phenylmethoxyphenyl)-N-[5-(phenyl...)
Show SMILES O=C(Nc1nc2CN(Cc3ccccc3)CCc2s1)C(=C\c1ccc(OCc2ccccc2)cc1)\C#N
Show InChI InChI=1S/C30H26N4O2S/c31-18-25(17-22-11-13-26(14-12-22)36-21-24-9-5-2-6-10-24)29(35)33-30-32-27-20-34(16-15-28(27)37-30)19-23-7-3-1-4-8-23/h1-14,17H,15-16,19-21H2,(H,32,33,35)/b25-17+
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM39716
PNG
((4Z)-4-[[[4-(2-furanyl)-2-propan-2-ylimino-3-thiaz...)
Show SMILES CC(C)N=c1scc(-c2ccco2)n1N=Cc1ccc(O)c(O)c1
Show InChI InChI=1S/C17H17N3O3S/c1-11(2)19-17-20(13(10-24-17)16-4-3-7-23-16)18-9-12-5-6-14(21)15(22)8-12/h3-11,21-22H,1-2H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66360
PNG
(4-(3,5-dimethylbenzoyl)-1,3-dihydroquinoxalin-2-on...)
Show SMILES Cc1cc(C)cc(c1)C(=O)N1CC(=O)Nc2ccccc12
Show InChI InChI=1S/C17H16N2O2/c1-11-7-12(2)9-13(8-11)17(21)19-10-16(20)18-14-5-3-4-6-15(14)19/h3-9H,10H2,1-2H3,(H,18,20)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM39730
PNG
(2-(1-naphthalenyl)-N-[2,2,2-trichloro-1-[[(2,5-dim...)
Show SMILES Cc1ccc(C)c(NC(=S)NC(NC(=O)Cc2cccc3ccccc23)C(Cl)(Cl)Cl)c1
Show InChI InChI=1S/C23H22Cl3N3OS/c1-14-10-11-15(2)19(12-14)27-22(31)29-21(23(24,25)26)28-20(30)13-17-8-5-7-16-6-3-4-9-18(16)17/h3-12,21H,13H2,1-2H3,(H,28,30)(H2,27,29,31)
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n/an/an/an/a 5.84E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM63039
PNG
(2-[6-(4-chlorophenyl)-3-cyano-4-(trifluoromethyl)p...)
Show SMILES Cc1coc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)-c2ccc(Cl)cc2)n1
Show InChI InChI=1S/C19H12ClF3N4O2S/c1-10-8-29-18(25-10)27-16(28)9-30-17-13(7-24)14(19(21,22)23)6-15(26-17)11-2-4-12(20)5-3-11/h2-6,8H,9H2,1H3,(H,25,27,28)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM34707
PNG
(MLS000571067 | SMR000150695 | [(2,5-dimethyl-4-oxi...)
Show SMILES Oc1cc(=C)c(NOS(=O)(=O)c2ccccc2)cc1=C
Show InChI InChI=1S/C14H13NO4S/c1-10-9-14(16)11(2)8-13(10)15-19-20(17,18)12-6-4-3-5-7-12/h3-9,15-16H,1-2H2
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66361
PNG
(3-(4-Methoxy-phenyl)-3,4-dihydro-1-oxa-4-aza-diben...)
Show SMILES COc1ccc(cc1)C1Nc2ccc3ccccc3c2-c2c1c(=O)oc1ccccc21
Show InChI InChI=1S/C27H19NO3/c1-30-18-13-10-17(11-14-18)26-25-24(20-8-4-5-9-22(20)31-27(25)29)23-19-7-3-2-6-16(19)12-15-21(23)28-26/h2-15,26,28H,1H3
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n/an/an/an/a 1.10E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66362
PNG
(2-(3,4-dimethoxyphenyl)-1-(4-methoxyphenyl)-6-oxid...)
Show SMILES COc1ccc(cc1)N1C(C(CCC1=O)C(O)=O)c1ccc(OC)c(OC)c1
Show InChI InChI=1S/C21H23NO6/c1-26-15-7-5-14(6-8-15)22-19(23)11-9-16(21(24)25)20(22)13-4-10-17(27-2)18(12-13)28-3/h4-8,10,12,16,20H,9,11H2,1-3H3,(H,24,25)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66363
PNG
(3,5-bis(difluoromethyl)-1-{5-[(2-naphthyloxy)methy...)
Show SMILES OC1(CC(=NN1C(=O)c1ccc(COc2ccc3ccccc3c2)o1)C(F)F)C(F)F
Show InChI InChI=1S/C21H16F4N2O4/c22-18(23)16-10-21(29,20(24)25)27(26-16)19(28)17-8-7-15(31-17)11-30-14-6-5-12-3-1-2-4-13(12)9-14/h1-9,18,20,29H,10-11H2
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n/an/an/an/a 4.56E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM54207
PNG
(MLS000538647 | N-[4-(3,4-dimethylphenyl)-5-methyl-...)
Show SMILES Cc1sc(NC(=O)c2nn(C)cc2[N+]([O-])=O)nc1-c1ccc(C)c(C)c1
Show InChI InChI=1S/C17H17N5O3S/c1-9-5-6-12(7-10(9)2)14-11(3)26-17(18-14)19-16(23)15-13(22(24)25)8-21(4)20-15/h5-8H,1-4H3,(H,18,19,23)
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n/an/an/an/a 6.26E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66364
PNG
(2-({5-[2-(4-bromophenyl)-2-oxoethyl]-3-cyano-4,6-d...)
Show SMILES Cc1cccc(NC(=O)CSc2nc(C)c(CC(=O)c3ccc(Br)cc3)c(C)c2C#N)c1C
Show InChI InChI=1S/C26H24BrN3O2S/c1-15-6-5-7-23(16(15)2)30-25(32)14-33-26-22(13-28)17(3)21(18(4)29-26)12-24(31)19-8-10-20(27)11-9-19/h5-11H,12,14H2,1-4H3,(H,30,32)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66365
PNG
(2-[({[(2,5-dimethylphenyl)sulfonyl]amino}acetyl)am...)
Show SMILES CC1CCc2c(C1)sc(NC(=O)CNS(=O)(=O)c1cc(C)ccc1C)c2C(N)=O
Show InChI InChI=1S/C20H25N3O4S2/c1-11-5-7-14-15(8-11)28-20(18(14)19(21)25)23-17(24)10-22-29(26,27)16-9-12(2)4-6-13(16)3/h4,6,9,11,22H,5,7-8,10H2,1-3H3,(H2,21,25)(H,23,24)
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n/an/an/an/a 1.11E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66366
PNG
(2-[(4-acetylanilino)-oxomethyl]-3-amino-4-(4-metho...)
Show SMILES CCOC(=O)c1c(C)nc2sc(C(=O)Nc3ccc(cc3)C(C)=O)c(N)c2c1-c1ccc(OC)cc1
Show InChI InChI=1S/C27H25N3O5S/c1-5-35-27(33)20-14(2)29-26-22(21(20)17-8-12-19(34-4)13-9-17)23(28)24(36-26)25(32)30-18-10-6-16(7-11-18)15(3)31/h6-13H,5,28H2,1-4H3,(H,30,32)
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Broad Institute

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Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66367
PNG
(2-{2-[(5-{[(4-chlorobenzyl)(phenylsulfonyl)amino]m...)
Show SMILES Fc1ccc(NC(=O)C(=O)NN=Cc2ccc(CN(Cc3ccc(Cl)cc3)S(=O)(=O)c3ccccc3)o2)cc1
Show InChI InChI=1S/C27H22ClFN4O5S/c28-20-8-6-19(7-9-20)17-33(39(36,37)25-4-2-1-3-5-25)18-24-15-14-23(38-24)16-30-32-27(35)26(34)31-22-12-10-21(29)11-13-22/h1-16H,17-18H2,(H,31,34)(H,32,35)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM63064
PNG
(4-nitro-N-[3-nitro-5-(4-methoxyphenoxy)phenyl]-1-m...)
Show SMILES COc1ccc(Oc2cc(NC(=O)c3nn(C)cc3[N+]([O-])=O)cc(c2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C18H15N5O7/c1-21-10-16(23(27)28)17(20-21)18(24)19-11-7-12(22(25)26)9-15(8-11)30-14-5-3-13(29-2)4-6-14/h3-10H,1-2H3,(H,19,24)
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n/an/an/an/a 7.21E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66368
PNG
(2-[(5E)-2,4-diketo-5-[(5-piperidino-2-furyl)methyl...)
Show SMILES CC(C)OC(=O)CN1C(=O)S\C(=C\c2ccc(o2)N2CCCCC2)C1=O
Show InChI InChI=1S/C18H22N2O5S/c1-12(2)24-16(21)11-20-17(22)14(26-18(20)23)10-13-6-7-15(25-13)19-8-4-3-5-9-19/h6-7,10,12H,3-5,8-9,11H2,1-2H3/b14-10+
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n/an/an/an/a>3.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM57282
PNG
(MLS000539132 | N-[1-(2,6-dichlorobenzyl)-3,5-dimet...)
Show SMILES Cc1nn(Cc2c(Cl)cccc2Cl)c(C)c1NC(=O)c1cn(nc1-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C28H23Cl2N5O/c1-18-26(19(2)34(32-18)16-22-24(29)14-9-15-25(22)30)31-28(36)23-17-35(21-12-7-4-8-13-21)33-27(23)20-10-5-3-6-11-20/h3-15,17H,16H2,1-2H3,(H,31,36)
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n/an/an/an/a 1.51E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66369
PNG
(2-(4-chloranyl-5-methyl-3-nitro-pyrazol-1-yl)-N-[1...)
Show SMILES Cc1nn(Cc2ccc(Cl)cc2Cl)c(C)c1NC(=O)Cn1nc(c(Cl)c1C)[N+]([O-])=O
Show InChI InChI=1S/C18H17Cl3N6O3/c1-9-17(11(3)25(23-9)7-12-4-5-13(19)6-14(12)20)22-15(28)8-26-10(2)16(21)18(24-26)27(29)30/h4-6H,7-8H2,1-3H3,(H,22,28)
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n/an/an/an/a 5.11E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM50308501
PNG
(CHEMBL603129 | Ethyl 5-benzoyl-4-phenylthiazol-2-y...)
Show SMILES CCOC(=O)Nc1nc(c(s1)C(=O)c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C19H16N2O3S/c1-2-24-19(23)21-18-20-15(13-9-5-3-6-10-13)17(25-18)16(22)14-11-7-4-8-12-14/h3-12H,2H2,1H3,(H,20,21,23)
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n/an/an/an/a>3.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM54208
PNG
(1-methyl-N-[5-methyl-4-(4-methylphenyl)-1,3-thiazo...)
Show SMILES Cc1sc(NC(=O)c2nn(C)cc2[N+]([O-])=O)nc1-c1ccc(C)cc1
Show InChI InChI=1S/C16H15N5O3S/c1-9-4-6-11(7-5-9)13-10(2)25-16(17-13)18-15(22)14-12(21(23)24)8-20(3)19-14/h4-8H,1-3H3,(H,17,18,22)
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n/an/an/an/a 9.72E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66370
PNG
(2-[3-cyano-6-phenyl-4-(3,4,5-trimethoxyphenyl)pyri...)
Show SMILES COc1cc(cc(OC)c1OC)-c1cc(nc(SCC(=O)Nc2nccs2)c1C#N)-c1ccccc1
Show InChI InChI=1S/C26H22N4O4S2/c1-32-21-11-17(12-22(33-2)24(21)34-3)18-13-20(16-7-5-4-6-8-16)29-25(19(18)14-27)36-15-23(31)30-26-28-9-10-35-26/h4-13H,15H2,1-3H3,(H,28,30,31)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66371
PNG
(2-[3-(4-bromophenyl)-4-oxidanylidene-quinazolin-2-...)
Show SMILES Cc1nn(c(C)c1C=NNC(=O)CSc1nc2ccccc2c(=O)n1-c1ccc(Br)cc1)-c1ccccc1
Show InChI InChI=1S/C28H23BrN6O2S/c1-18-24(19(2)35(33-18)22-8-4-3-5-9-22)16-30-32-26(36)17-38-28-31-25-11-7-6-10-23(25)27(37)34(28)21-14-12-20(29)13-15-21/h3-16H,17H2,1-2H3,(H,32,36)
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n/an/an/an/a 4.24E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66372
PNG
(5-[(2-methoxy-4-propyl-phenoxy)methyl]-N-[(3-nitro...)
Show SMILES CCCc1ccc(OCc2ccc(o2)C(=O)N\N=C\c2cccc(c2)[N+]([O-])=O)c(OC)c1
Show InChI InChI=1S/C23H23N3O6/c1-3-5-16-8-10-20(22(13-16)30-2)31-15-19-9-11-21(32-19)23(27)25-24-14-17-6-4-7-18(12-17)26(28)29/h4,6-14H,3,5,15H2,1-2H3,(H,25,27)/b24-14+
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n/an/an/an/a 7.22E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66373
PNG
(MLS000538833 | N-cyclohexyl-2-[({[3-(4-fluoropheny...)
Show SMILES Fc1ccc(C=CC(=O)NC(=S)Nc2ccccc2C(=O)NC2CCCCC2)cc1
Show InChI InChI=1S/C23H24FN3O2S/c24-17-13-10-16(11-14-17)12-15-21(28)27-23(30)26-20-9-5-4-8-19(20)22(29)25-18-6-2-1-3-7-18/h4-5,8-15,18H,1-3,6-7H2,(H,25,29)(H2,26,27,28,30)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66374
PNG
(2-[(4-chlorobenzoyl)amino]-4-methyl-valeric acid [...)
Show SMILES CC(C)CC(NC(=O)c1ccc(Cl)cc1)C(=O)OCC(=O)c1ccc2OCC(=O)Nc2c1
Show InChI InChI=1S/C23H23ClN2O6/c1-13(2)9-18(26-22(29)14-3-6-16(24)7-4-14)23(30)32-11-19(27)15-5-8-20-17(10-15)25-21(28)12-31-20/h3-8,10,13,18H,9,11-12H2,1-2H3,(H,25,28)(H,26,29)
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n/an/an/an/a 5.35E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66375
PNG
(3-({4-nitro-1H-pyrazol-1-yl}methyl)-N-[1-(4-isopro...)
Show SMILES CCC(NC(=O)c1cccc(Cn2cc(cn2)[N+]([O-])=O)c1)c1ccc(cc1)C(C)C
Show InChI InChI=1S/C23H26N4O3/c1-4-22(19-10-8-18(9-11-19)16(2)3)25-23(28)20-7-5-6-17(12-20)14-26-15-21(13-24-26)27(29)30/h5-13,15-16,22H,4,14H2,1-3H3,(H,25,28)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM47574
PNG
((5Z)-3-[2-(1H-indol-3-yl)ethyl]-5-[(5-morpholin-4-...)
Show SMILES O=C1N(CCc2c[nH]c3ccccc23)\C(S\C1=C/c1ccc(o1)N1CCOCC1)=N\c1ccccc1
Show InChI InChI=1S/C28H26N4O3S/c33-27-25(18-22-10-11-26(35-22)31-14-16-34-17-15-31)36-28(30-21-6-2-1-3-7-21)32(27)13-12-20-19-29-24-9-5-4-8-23(20)24/h1-11,18-19,29H,12-17H2/b25-18-,30-28-
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n/an/an/an/a 9.16E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66376
PNG
(2-(3-chlorophenyl)-5-methyl-4-[(1,3,5-triazatricyc...)
Show SMILES CC1=NN(C(=O)\C1=C\NC12CN3CN(CN(C3)C1)C2)c1cccc(Cl)c1
Show InChI InChI=1S/C18H21ClN6O/c1-13-16(17(26)25(21-13)15-4-2-3-14(19)5-15)6-20-18-7-22-10-23(8-18)12-24(9-18)11-22/h2-6,20H,7-12H2,1H3/b16-6+
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM51690
PNG
(MLS000521226 | N-[4-[5-(2-thenoylamino)-1,3-benzox...)
Show SMILES O=C(Nc1ccc(cc1)-c1nc2cc(NC(=O)c3cccs3)ccc2o1)c1cccs1
Show InChI InChI=1S/C23H15N3O3S2/c27-21(19-3-1-11-30-19)24-15-7-5-14(6-8-15)23-26-17-13-16(9-10-18(17)29-23)25-22(28)20-4-2-12-31-20/h1-13H,(H,24,27)(H,25,28)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM34717
PNG
(2-[(E)-2-(4-hydroxyphenyl)ethenyl]-1,3,3-trimethyl...)
Show SMILES COC(=O)c1ccc2c(c1)C(C)(C)C(\C=C\c1ccc(O)cc1)=[N+]2C
Show InChI InChI=1S/C21H21NO3/c1-21(2)17-13-15(20(24)25-4)8-11-18(17)22(3)19(21)12-7-14-5-9-16(23)10-6-14/h5-13H,1-4H3/p+1
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n/an/an/an/a 1.52E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM33097
PNG
(3-[[7-(1,3-benzothiazol-2-ylsulfanyl)-4-nitro-2,1,...)
Show SMILES CC(=O)OCCCNc1cc(Sc2nc3ccccc3s2)c2nonc2c1[N+]([O-])=O
Show InChI InChI=1S/C18H15N5O5S2/c1-10(24)27-8-4-7-19-12-9-14(15-16(22-28-21-15)17(12)23(25)26)30-18-20-11-5-2-3-6-13(11)29-18/h2-3,5-6,9,19H,4,7-8H2,1H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM39763
PNG
(2-[(E)-2-(2-hydroxyphenyl)ethenyl]-1,3,3-trimethyl...)
Show SMILES COC(=O)c1ccc2c(c1)C(C)(C)C(\C=C\c1ccccc1O)=[N+]2C
Show InChI InChI=1S/C21H21NO3/c1-21(2)16-13-15(20(24)25-4)9-11-17(16)22(3)19(21)12-10-14-7-5-6-8-18(14)23/h5-13H,1-4H3/p+1
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n/an/an/an/a 1.26E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66377
PNG
(1-methyl-5-(4-methyl-5-methylsulfanyl-1,2,4-triazo...)
Show SMILES CSc1nnc(-c2cc3c(nn(C)c3s2)-c2ccccc2)n1C
Show InChI InChI=1S/C16H15N5S2/c1-20-14(17-18-16(20)22-3)12-9-11-13(10-7-5-4-6-8-10)19-21(2)15(11)23-12/h4-9H,1-3H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM65076
PNG
((4,5-dichloro-6-oxopyridazin-1-yl)methyl 3-(triflu...)
Show SMILES FC(F)(F)c1cccc(c1)C(=O)OCn1ncc(Cl)c(Cl)c1=O
Show InChI InChI=1S/C13H7Cl2F3N2O3/c14-9-5-19-20(11(21)10(9)15)6-23-12(22)7-2-1-3-8(4-7)13(16,17)18/h1-5H,6H2
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66378
PNG
(1-(4-chlorobenzyl)-3-phenyl-1-(3,3,3-trifluoro-2-h...)
Show SMILES OC(CN(Cc1ccc(Cl)cc1)C(=O)Nc1ccccc1)C(F)(F)F
Show InChI InChI=1S/C17H16ClF3N2O2/c18-13-8-6-12(7-9-13)10-23(11-15(24)17(19,20)21)16(25)22-14-4-2-1-3-5-14/h1-9,15,24H,10-11H2,(H,22,25)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66379
PNG
(2-[4-(4-pyridin-2-ylpyrimidin-2-yl)phenoxy]propane...)
Show SMILES CC(Oc1ccc(cc1)-c1nccc(n1)-c1ccccn1)C(=O)NN
Show InChI InChI=1S/C18H17N5O2/c1-12(18(24)23-19)25-14-7-5-13(6-8-14)17-21-11-9-16(22-17)15-4-2-3-10-20-15/h2-12H,19H2,1H3,(H,23,24)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66380
PNG
(2-({5-[2-(4-bromophenyl)-2-oxoethyl]-3-cyano-4,6-d...)
Show SMILES Cc1cccc(C)c1NC(=O)CSc1nc(C)c(CC(=O)c2ccc(Br)cc2)c(C)c1C#N
Show InChI InChI=1S/C26H24BrN3O2S/c1-15-6-5-7-16(2)25(15)30-24(32)14-33-26-22(13-28)17(3)21(18(4)29-26)12-23(31)19-8-10-20(27)11-9-19/h5-11H,12,14H2,1-4H3,(H,30,32)
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n/an/an/an/a 3.02E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66381
PNG
(5-amino-3-ethyl-1-(6-naphthalen-1-yloxy-2-phenylpy...)
Show SMILES CCc1nn(c(N)c1C#N)-c1cc(Oc2cccc3ccccc23)nc(n1)-c1ccccc1
Show InChI InChI=1S/C26H20N6O/c1-2-21-20(16-27)25(28)32(31-21)23-15-24(30-26(29-23)18-10-4-3-5-11-18)33-22-14-8-12-17-9-6-7-13-19(17)22/h3-15H,2,28H2,1H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM41056
PNG
(2-{4-[2-(1-benzofuran-2-ylcarbonyl)carbohydrazonoy...)
Show SMILES Clc1cc(C=NNC(=O)c2cc3ccccc3o2)ccc1OCC(=O)Nc1ccccc1
Show InChI InChI=1S/C24H18ClN3O4/c25-19-12-16(10-11-21(19)31-15-23(29)27-18-7-2-1-3-8-18)14-26-28-24(30)22-13-17-6-4-5-9-20(17)32-22/h1-14H,15H2,(H,27,29)(H,28,30)
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n/an/an/an/a 6.55E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66382
PNG
(3-allyloxy-N-ethyl-N-(4-methoxyphenyl)-2-methyl-in...)
Show SMILES CCN(C(=O)c1ccc2c(OCC=C)n(C)nc2c1)c1ccc(OC)cc1
Show InChI InChI=1S/C21H23N3O3/c1-5-13-27-21-18-12-7-15(14-19(18)22-23(21)3)20(25)24(6-2)16-8-10-17(26-4)11-9-16/h5,7-12,14H,1,6,13H2,2-4H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66383
PNG
((Z)-3-(5-Morpholin-4-yl-furan-2-yl)-2-phenyl-acryl...)
Show SMILES N#C\C(=C/c1ccc(o1)N1CCOCC1)c1ccccc1
Show InChI InChI=1S/C17H16N2O2/c18-13-15(14-4-2-1-3-5-14)12-16-6-7-17(21-16)19-8-10-20-11-9-19/h1-7,12H,8-11H2/b15-12+
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM63097
PNG
(MLS000556132 | N-[2-(cyclopentylamino)-2-keto-1-(2...)
Show SMILES COc1ccc(OC)c(c1)N(C(C(=O)NC1CCCC1)c1cccs1)C(=O)C#C
Show InChI InChI=1S/C22H24N2O4S/c1-4-20(25)24(17-14-16(27-2)11-12-18(17)28-3)21(19-10-7-13-29-19)22(26)23-15-8-5-6-9-15/h1,7,10-15,21H,5-6,8-9H2,2-3H3,(H,23,26)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66384
PNG
(3-phenyl-2-phenylimino-5-(phenylmethyl)-1,3-thiazo...)
Show SMILES O=C1C(Cc2ccccc2)S\C(=N/c2ccccc2)N1c1ccccc1
Show InChI InChI=1S/C22H18N2OS/c25-21-20(16-17-10-4-1-5-11-17)26-22(23-18-12-6-2-7-13-18)24(21)19-14-8-3-9-15-19/h1-15,20H,16H2/b23-22-
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
Bcl-2-like protein 11


(Homo sapiens)
BDBM66385
PNG
(2-[3-cyano-4-(4-fluorophenyl)-6-phenyl-pyridin-2-y...)
Show SMILES CCc1nnc(NC(=O)CSc2nc(cc(-c3ccc(F)cc3)c2C#N)-c2ccccc2)s1
Show InChI InChI=1S/C24H18FN5OS2/c1-2-22-29-30-24(33-22)28-21(31)14-32-23-19(13-26)18(15-8-10-17(25)11-9-15)12-20(27-23)16-6-4-3-5-7-16/h3-12H,2,14H2,1H3,(H,28,30,31)
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n/an/an/an/a 2.42E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair
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