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Compile Data Set for Download or QSAR

Found 10 hits of Enz. Inhib. data with enzyme = 'Beta-catenin-interacting protein 1' and Substrate = 'to-be-curated'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-catenin-interacting protein 1


()
BDBM269261
PNG
(US10071086, Compound 9)
Show SMILES CC(C)Nc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cncc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C26H19FN8/c1-14(2)31-19-7-16(9-28-11-19)17-8-20-24(34-35-25(20)30-10-17)26-32-22-13-29-12-21(23(22)33-26)15-4-3-5-18(27)6-15/h3-14,31H,1-2H3/b26-24+
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 67n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Compounds of Formulas (I) or (II) were screened in a β-catenin-based reporter assay in a transformed human bronchial epithelial cell line (NL-20...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair
Beta-catenin-interacting protein 1


()
BDBM269257
PNG
(US10071086, Compound 5)
Show SMILES Nc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cncc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C23H13FN8/c24-15-3-1-2-12(4-15)18-10-27-11-19-20(18)30-23(29-19)21-17-6-14(8-28-22(17)32-31-21)13-5-16(25)9-26-7-13/h1-11H,25H2/b23-21+
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 175n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Compounds of Formulas (I) or (II) were screened in a β-catenin-based reporter assay in a transformed human bronchial epithelial cell line (NL-20...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair
Beta-catenin-interacting protein 1


()
BDBM269263
PNG
(US10071086, Compound 11)
Show SMILES CN1CCN(CC1)c1cc(F)cc(c1)-c1cncc2[nH]c(nc12)-c1n[nH]c2ncc(cc12)-c1cccnc1
Show InChI InChI=1S/C28H22FN9/c1-37-5-7-38(8-6-37)21-10-18(9-20(29)12-21)23-15-31-16-24-25(23)34-28(33-24)26-22-11-19(14-32-27(22)36-35-26)17-3-2-4-30-13-17/h2-4,9-16H,5-8H2,1H3/b28-26+
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 210n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Compounds of Formulas (I) or (II) were screened in a β-catenin-based reporter assay in a transformed human bronchial epithelial cell line (NL-20...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair
Beta-catenin-interacting protein 1


()
BDBM269262
PNG
(US10071086, Compound 10)
Show SMILES CN1CCN(Cc2cc(F)cc(c2)-c2cncc3[nH]c(nc23)-c2n[nH]c3ncc(cc23)-c2cccnc2)CC1
Show InChI InChI=1S/C29H24FN9/c1-38-5-7-39(8-6-38)17-18-9-20(11-22(30)10-18)24-15-32-16-25-26(24)35-29(34-25)27-23-12-21(14-33-28(23)37-36-27)19-3-2-4-31-13-19/h2-4,9-16H,5-8,17H2,1H3/b29-27+
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 247n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Compounds of Formulas (I) or (II) were screened in a β-catenin-based reporter assay in a transformed human bronchial epithelial cell line (NL-20...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair
Beta-catenin-interacting protein 1


()
BDBM270306
PNG
(US10071086, Compound 12)
Show SMILES CN(C)CCNc1cc(F)cc(c1)-c1cncc2[nH]c(nc12)-c1n[nH]c2ncc(cc12)-c1cccnc1
Show InChI InChI=1S/C27H22FN9/c1-37(2)7-6-31-20-9-17(8-19(28)11-20)22-14-30-15-23-24(22)34-27(33-23)25-21-10-18(13-32-26(21)36-35-25)16-4-3-5-29-12-16/h3-5,8-15,31H,6-7H2,1-2H3/b27-25+
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 310n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Compounds of Formulas (I) or (II) were screened in a β-catenin-based reporter assay in a transformed human bronchial epithelial cell line (NL-20...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair
Beta-catenin-interacting protein 1


()
BDBM270451
PNG
(US10071086, Compound 18)
Show SMILES CN(C)Cc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cncc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C26H19FN8/c1-35(2)14-15-6-17(10-28-9-15)18-8-20-24(33-34-25(20)30-11-18)26-31-22-13-29-12-21(23(22)32-26)16-4-3-5-19(27)7-16/h3-13H,14H2,1-2H3/b26-24+
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 440n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Compounds of Formulas (I) or (II) were screened in a β-catenin-based reporter assay in a transformed human bronchial epithelial cell line (NL-20...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair
Beta-catenin-interacting protein 1


()
BDBM275495
PNG
(US10071086, Compound 452)
Show SMILES CN(C)Cc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cncc4[nH]3)-c3cccs3)c2c1
Show InChI InChI=1S/C24H18N8S/c1-32(2)13-14-6-15(9-25-8-14)16-7-17-22(30-31-23(17)27-10-16)24-28-19-12-26-11-18(21(19)29-24)20-4-3-5-33-20/h3-12H,13H2,1-2H3/b24-22+
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.09E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Compounds of Formulas (I) or (II) were screened in a β-catenin-based reporter assay in a transformed human bronchial epithelial cell line (NL-20...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair
Beta-catenin-interacting protein 1


()
BDBM269259
PNG
(US10071086, Compound 7)
Show SMILES CN(C)c1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cncc4[nH]3)-c3cccc(F)c3)c2c1
Show InChI InChI=1S/C25H17FN8/c1-34(2)18-7-15(9-27-11-18)16-8-19-23(32-33-24(19)29-10-16)25-30-21-13-28-12-20(22(21)31-25)14-4-3-5-17(26)6-14/h3-13H,1-2H3/b25-23+
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.90E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Compounds of Formulas (I) or (II) were screened in a β-catenin-based reporter assay in a transformed human bronchial epithelial cell line (NL-20...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair
Beta-catenin-interacting protein 1


()
BDBM270440
PNG
(US10071086, Compound 14)
Show SMILES CN(C)Cc1cc(F)cc(c1)-c1cncc2[nH]c(nc12)-c1n[nH]c2ncc(cc12)-c1cccnc1
Show InChI InChI=1S/C26H19FN8/c1-35(2)14-15-6-17(8-19(27)7-15)21-12-29-13-22-23(21)32-26(31-22)24-20-9-18(11-30-25(20)34-33-24)16-4-3-5-28-10-16/h3-13H,14H2,1-2H3/b26-24+
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.03E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Compounds of Formulas (I) or (II) were screened in a β-catenin-based reporter assay in a transformed human bronchial epithelial cell line (NL-20...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair
Beta-catenin-interacting protein 1


()
BDBM275766
PNG
((6S,9aS)-N-benzyl-6-(4-hydroxybenzyl)-8-(naphthale...)
Show SMILES Oc1ccc(CC2N3C(CN(Cc4cccc5ccccc45)C2=O)N(CCC3=O)C(=O)NCc2ccccc2)cc1
Show InChI InChI=1S/C33H32N4O4/c38-27-15-13-23(14-16-27)19-29-32(40)35(21-26-11-6-10-25-9-4-5-12-28(25)26)22-30-36(18-17-31(39)37(29)30)33(41)34-20-24-7-2-1-3-8-24/h1-16,29-30,38H,17-22H2,(H,34,41)
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.00E+3n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Compounds of Formulas (I) or (II) were screened in a β-catenin-based reporter assay in a transformed human bronchial epithelial cell line (NL-20...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair