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Compile Data Set for Download or QSAR

Found 265 hits of Enz. Inhib. data with enzyme = 'Carbonic anhydrase 9' and Substrate = 'BDBM10856'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM14718
PNG
(1-N-[5-Sulfamoyl-1,3,4-thiadiazol-2-yl-(aminosulfo...)
Show SMILES Cc1cc(C)[n+](c(C)c1)-c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C16H18N5O4S3/c1-10-8-11(2)21(12(3)9-10)13-4-6-14(7-5-13)28(24,25)20-15-18-19-16(26-15)27(17,22)23/h4-9H,1-3H3,(H,18,20)(H2,17,22,23)/q+1
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3n/an/an/an/an/an/an/an/a



Canadian Institutes of Health Research



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 47: 2337-47 (2004)


Article DOI: 10.1021/jm031079w
BindingDB Entry DOI: 10.7270/Q2DV1H4B
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11051
PNG
(N-[(2E)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thi...)
Show SMILES Cn1nc(sc1=NC(=O)CCS)S(N)(=O)=O
Show InChI InChI=1S/C6H10N4O3S3/c1-10-5(8-4(11)2-3-14)15-6(9-10)16(7,12)13/h14H,2-3H2,1H3,(H2,7,12,13)
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3.20n/an/an/an/an/an/an/an/a



Istituto di Biostrutture e Bioimmagini-CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 5544-51 (2006)


Article DOI: 10.1021/jm060531j
BindingDB Entry DOI: 10.7270/Q21J9805
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM12140
PNG
(4-(N-(4-nitrophenyl)aminocarbonyl-hydrazinocarbony...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C14H13N5O6S/c15-26(24,25)12-7-1-9(2-8-12)13(20)17-18-14(21)16-10-3-5-11(6-4-10)19(22)23/h1-8H,(H,17,20)(H2,15,24,25)(H2,16,18,21)
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3.20n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 2121-5 (2005)


Article DOI: 10.1021/jm0494826
BindingDB Entry DOI: 10.7270/Q25X275C
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11038
PNG
(2-butylamido-5-sulfonamidoindane | CHEMBL208531 | ...)
Show SMILES CCCCC(=O)NC1Cc2ccc(cc2C1)S(N)(=O)=O
Show InChI InChI=1S/C14H20N2O3S/c1-2-3-4-14(17)16-12-7-10-5-6-13(20(15,18)19)9-11(10)8-12/h5-6,9,12H,2-4,7-8H2,1H3,(H,16,17)(H2,15,18,19)
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3.40n/an/an/an/an/an/an/an/a



University of Namur



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 2743-9 (2006)


Article DOI: 10.1021/jm0600287
BindingDB Entry DOI: 10.7270/Q25B00PK
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11034
PNG
(1-pentafluorophenylamido-5-sulfonamidoindane | 2,3...)
Show SMILES NS(=O)(=O)c1ccc2C(CCc2c1)NC(=O)c1c(F)c(F)c(F)c(F)c1F
Show InChI InChI=1S/C16H11F5N2O3S/c17-11-10(12(18)14(20)15(21)13(11)19)16(24)23-9-4-1-6-5-7(27(22,25)26)2-3-8(6)9/h2-3,5,9H,1,4H2,(H,23,24)(H2,22,25,26)
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3.5n/an/an/an/an/an/an/an/a



University of Namur



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 2743-9 (2006)


Article DOI: 10.1021/jm0600287
BindingDB Entry DOI: 10.7270/Q25B00PK
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM33271
PNG
(azo-sulfonamide, 1f)
Show SMILES CN(CS([O-])(=O)=O)c1ccc(cc1)\N=N\c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C14H16N4O5S2/c1-18(10-24(19,20)21)13-6-2-11(3-7-13)16-17-12-4-8-14(9-5-12)25(15,22)23/h2-9H,10H2,1H3,(H2,15,22,23)(H,19,20,21)/p-1/b17-16+
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3.5n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem 17: 7093-9 (2009)


Article DOI: 10.1016/j.bmc.2009.09.003
BindingDB Entry DOI: 10.7270/Q2M32T4Q
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11049
PNG
(N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-3-sulfanylpr...)
Show SMILES NS(=O)(=O)c1nnc(NC(=O)CCS)s1
Show InChI InChI=1S/C5H8N4O3S3/c6-15(11,12)5-9-8-4(14-5)7-3(10)1-2-13/h13H,1-2H2,(H2,6,11,12)(H,7,8,10)
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3.60n/an/an/an/an/an/an/an/a



Istituto di Biostrutture e Bioimmagini-CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 5544-51 (2006)


Article DOI: 10.1021/jm060531j
BindingDB Entry DOI: 10.7270/Q21J9805
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11039
PNG
(2-nonylamido-5-sulfonamidoindane | CHEMBL208532 | ...)
Show SMILES CCCCCCCCCC(=O)NC1Cc2ccc(cc2C1)S(N)(=O)=O
Show InChI InChI=1S/C19H30N2O3S/c1-2-3-4-5-6-7-8-9-19(22)21-17-12-15-10-11-18(25(20,23)24)14-16(15)13-17/h10-11,14,17H,2-9,12-13H2,1H3,(H,21,22)(H2,20,23,24)
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3.70n/an/an/an/an/an/an/an/a



University of Namur



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 2743-9 (2006)


Article DOI: 10.1021/jm0600287
BindingDB Entry DOI: 10.7270/Q25B00PK
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM33281
PNG
(CHEMBL182455 | bis-sulfamate, 3)
Show SMILES NS(=O)(=O)OCCCCCCCCOS(N)(=O)=O
Show InChI InChI=1S/C8H20N2O6S2/c9-17(11,12)15-7-5-3-1-2-4-6-8-16-18(10,13)14/h1-8H2,(H2,9,11,12)(H2,10,13,14)
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4n/an/an/an/an/an/an/an/a



CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 52: 5990-8 (2009)


Article DOI: 10.1021/jm900641r
BindingDB Entry DOI: 10.7270/Q2GF0RVR
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM33268
PNG
(azo-sulfonamide, 1c)
Show SMILES CNc1ccc(cc1)\N=N\c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C13H14N4O2S/c1-15-10-2-4-11(5-3-10)16-17-12-6-8-13(9-7-12)20(14,18)19/h2-9,15H,1H3,(H2,14,18,19)/b17-16+
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4.90n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem 17: 7093-9 (2009)


Article DOI: 10.1016/j.bmc.2009.09.003
BindingDB Entry DOI: 10.7270/Q2M32T4Q
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM14719
PNG
(1-N-[5-Sulfamoyl-1,3,4-thiadiazol-2-yl-(aminosulfo...)
Show SMILES CC(C)c1cc(C)cc(C)[n+]1-c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C18H22N5O4S3/c1-11(2)16-10-12(3)9-13(4)23(16)14-5-7-15(8-6-14)30(26,27)22-17-20-21-18(28-17)29(19,24)25/h5-11H,1-4H3,(H,20,22)(H2,19,24,25)/q+1
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5n/an/an/an/an/an/an/an/a



Canadian Institutes of Health Research



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 47: 2337-47 (2004)


Article DOI: 10.1021/jm031079w
BindingDB Entry DOI: 10.7270/Q2DV1H4B
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM10888
PNG
(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)
Show SMILES NS(=O)(=O)Cc1noc2ccccc12
Show InChI InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)
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5n/an/an/an/an/an/an/an/a



Istituto di Biostrutture e Bioimmagini-CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 5544-51 (2006)


Article DOI: 10.1021/jm060531j
BindingDB Entry DOI: 10.7270/Q21J9805
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM14736
PNG
(1-N-[5-Sulfamoyl-1,3,4-thiadiazol-2-yl-(aminosulfo...)
Show SMILES Cc1cc(C)[n+](c(C)c1C)-c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C17H20N5O4S3/c1-10-9-11(2)22(13(4)12(10)3)14-5-7-15(8-6-14)29(25,26)21-16-19-20-17(27-16)28(18,23)24/h5-9H,1-4H3,(H,19,21)(H2,18,23,24)/q+1
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5n/an/an/an/an/an/an/an/a



Canadian Institutes of Health Research



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 47: 2337-47 (2004)


Article DOI: 10.1021/jm031079w
BindingDB Entry DOI: 10.7270/Q2DV1H4B
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM12142
PNG
(4-(N-(4-biphenyl)aminocarbonyl-hydrazinocarbonyl)-...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C20H18N4O4S/c21-29(27,28)18-12-8-16(9-13-18)19(25)23-24-20(26)22-17-10-6-15(7-11-17)14-4-2-1-3-5-14/h1-13H,(H,23,25)(H2,21,27,28)(H2,22,24,26)
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5.40n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 2121-5 (2005)


Article DOI: 10.1021/jm0494826
BindingDB Entry DOI: 10.7270/Q25X275C
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM12151
PNG
(4-(N-(4-chlorophenyl)sulfonylaminocarbonyl-hydrazi...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C14H13ClN4O6S2/c15-10-3-7-12(8-4-10)27(24,25)19-14(21)18-17-13(20)9-1-5-11(6-2-9)26(16,22)23/h1-8H,(H,17,20)(H2,16,22,23)(H2,18,19,21)
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5.40n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 2121-5 (2005)


Article DOI: 10.1021/jm0494826
BindingDB Entry DOI: 10.7270/Q25X275C
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM33270
PNG
(azo-sulfonamide, 1e)
Show SMILES NS(=O)(=O)c1ccc(cc1)\N=N\c1ccc(NCS([O-])(=O)=O)cc1
Show InChI InChI=1S/C13H14N4O5S2/c14-24(21,22)13-7-5-12(6-8-13)17-16-11-3-1-10(2-4-11)15-9-23(18,19)20/h1-8,15H,9H2,(H2,14,21,22)(H,18,19,20)/p-1/b17-16+
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5.40n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem 17: 7093-9 (2009)


Article DOI: 10.1016/j.bmc.2009.09.003
BindingDB Entry DOI: 10.7270/Q2M32T4Q
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM12149
PNG
(4-(N-(4-methylphenyl)sulfonylaminocarbonyl-hydrazi...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)NNC(=O)c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H16N4O6S2/c1-10-2-6-13(7-3-10)27(24,25)19-15(21)18-17-14(20)11-4-8-12(9-5-11)26(16,22)23/h2-9H,1H3,(H,17,20)(H2,16,22,23)(H2,18,19,21)
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5.80n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 2121-5 (2005)


Article DOI: 10.1021/jm0494826
BindingDB Entry DOI: 10.7270/Q25X275C
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM33273
PNG
(azo-sulfonamide, 2b)
Show SMILES Nc1ccc(cc1)\N=N\c1cccc(c1)S(N)(=O)=O
Show InChI InChI=1S/C12H12N4O2S/c13-9-4-6-10(7-5-9)15-16-11-2-1-3-12(8-11)19(14,17)18/h1-8H,13H2,(H2,14,17,18)/b16-15+
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5.90n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem 17: 7093-9 (2009)


Article DOI: 10.1016/j.bmc.2009.09.003
BindingDB Entry DOI: 10.7270/Q2M32T4Q
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM33267
PNG
(azo-sulfonamide, 1b)
Show SMILES Nc1ccc(cc1)\N=N\c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C12H12N4O2S/c13-9-1-3-10(4-2-9)15-16-11-5-7-12(8-6-11)19(14,17)18/h1-8H,13H2,(H2,14,17,18)/b16-15+
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6n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem 17: 7093-9 (2009)


Article DOI: 10.1016/j.bmc.2009.09.003
BindingDB Entry DOI: 10.7270/Q2M32T4Q
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM14722
PNG
(1-N-[5-Sulfamoyl-1,3,4-thiadiazol-2-yl-(aminosulfo...)
Show SMILES Cc1cc(cc(C)[n+]1-c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O)-c1ccccc1
Show InChI InChI=1S/C21H20N5O4S3/c1-14-12-17(16-6-4-3-5-7-16)13-15(2)26(14)18-8-10-19(11-9-18)33(29,30)25-20-23-24-21(31-20)32(22,27)28/h3-13H,1-2H3,(H,23,25)(H2,22,27,28)/q+1
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6n/an/an/an/an/an/an/an/a



Canadian Institutes of Health Research



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 47: 2337-47 (2004)


Article DOI: 10.1021/jm031079w
BindingDB Entry DOI: 10.7270/Q2DV1H4B
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM33272
PNG
(azo-sulfonamide, 2a)
Show SMILES NS(=O)(=O)c1cccc(c1)N=Nc1ccc(O)cc1
Show InChI InChI=1S/C12H11N3O3S/c13-19(17,18)12-3-1-2-10(8-12)15-14-9-4-6-11(16)7-5-9/h1-8,16H,(H2,13,17,18)
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6.10n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem 17: 7093-9 (2009)


Article DOI: 10.1016/j.bmc.2009.09.003
BindingDB Entry DOI: 10.7270/Q2M32T4Q
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM12150
PNG
(N-({[(4-fluorobenzene)sulfonyl]carbamoyl}amino)-4-...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)NS(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C14H13FN4O6S2/c15-10-3-7-12(8-4-10)27(24,25)19-14(21)18-17-13(20)9-1-5-11(6-2-9)26(16,22)23/h1-8H,(H,17,20)(H2,16,22,23)(H2,18,19,21)
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6.20n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 2121-5 (2005)


Article DOI: 10.1021/jm0494826
BindingDB Entry DOI: 10.7270/Q25X275C
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM33266
PNG
(CHEMBL379206 | azo-sulfonamide, 1a | p-Phenyldiaze...)
Show SMILES NS(=O)(=O)c1ccc(cc1)N=Nc1ccc(O)cc1
Show InChI InChI=1S/C12H11N3O3S/c13-19(17,18)12-7-3-10(4-8-12)15-14-9-1-5-11(16)6-2-9/h1-8,16H,(H2,13,17,18)
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6.40n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem 17: 7093-9 (2009)


Article DOI: 10.1016/j.bmc.2009.09.003
BindingDB Entry DOI: 10.7270/Q2M32T4Q
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM33274
PNG
(azo-sulfonamide, 2d)
Show SMILES CN(C)c1ccc(cc1)\N=N\c1cccc(c1)S(N)(=O)=O
Show InChI InChI=1S/C14H16N4O2S/c1-18(2)13-8-6-11(7-9-13)16-17-12-4-3-5-14(10-12)21(15,19)20/h3-10H,1-2H3,(H2,15,19,20)/b17-16+
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6.40n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem 17: 7093-9 (2009)


Article DOI: 10.1016/j.bmc.2009.09.003
BindingDB Entry DOI: 10.7270/Q2M32T4Q
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM33269
PNG
(CHEMBL277836 | azo-sulfonamide, 1d | cid_75522 | p...)
Show SMILES CN(C)c1ccc(cc1)\N=N\c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C14H16N4O2S/c1-18(2)13-7-3-11(4-8-13)16-17-12-5-9-14(10-6-12)21(15,19)20/h3-10H,1-2H3,(H2,15,19,20)/b17-16+
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6.60n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem 17: 7093-9 (2009)


Article DOI: 10.1016/j.bmc.2009.09.003
BindingDB Entry DOI: 10.7270/Q2M32T4Q
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM12144
PNG
(4-(N-(4-benzyloxyphenyl)aminocarbonyl-hydrazinocar...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C21H20N4O5S/c22-31(28,29)19-12-6-16(7-13-19)20(26)24-25-21(27)23-17-8-10-18(11-9-17)30-14-15-4-2-1-3-5-15/h1-13H,14H2,(H,24,26)(H2,22,28,29)(H2,23,25,27)
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7n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 2121-5 (2005)


Article DOI: 10.1021/jm0494826
BindingDB Entry DOI: 10.7270/Q25X275C
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM33282
PNG
(CHEMBL171476 | bis-sulfamate, 4)
Show SMILES NS(=O)(=O)OCCCCCCCCCCOS(N)(=O)=O
Show InChI InChI=1S/C10H24N2O6S2/c11-19(13,14)17-9-7-5-3-1-2-4-6-8-10-18-20(12,15)16/h1-10H2,(H2,11,13,14)(H2,12,15,16)
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7n/an/an/an/an/an/an/an/a



CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 52: 5990-8 (2009)


Article DOI: 10.1021/jm900641r
BindingDB Entry DOI: 10.7270/Q2GF0RVR
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM12137
PNG
(4-(N-(3,4-dichlorophenyl)aminocarbonyl-hydrazinoca...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C14H12Cl2N4O4S/c15-11-6-3-9(7-12(11)16)18-14(22)20-19-13(21)8-1-4-10(5-2-8)25(17,23)24/h1-7H,(H,19,21)(H2,17,23,24)(H2,18,20,22)
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7.90n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 2121-5 (2005)


Article DOI: 10.1021/jm0494826
BindingDB Entry DOI: 10.7270/Q25X275C
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM12143
PNG
(4-(N-(4-phenoxyphenyl)aminocarbonyl-hydrazinocarbo...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C20H18N4O5S/c21-30(27,28)18-12-6-14(7-13-18)19(25)23-24-20(26)22-15-8-10-17(11-9-15)29-16-4-2-1-3-5-16/h1-13H,(H,23,25)(H2,21,27,28)(H2,22,24,26)
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7.90n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 2121-5 (2005)


Article DOI: 10.1021/jm0494826
BindingDB Entry DOI: 10.7270/Q25X275C
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM12138
PNG
(4-(N-(4-acetylphenyl)aminocarbonyl-hydrazinocarbon...)
Show SMILES CC(=O)c1ccc(NC(=O)NNC(=O)c2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C16H16N4O5S/c1-10(21)11-2-6-13(7-3-11)18-16(23)20-19-15(22)12-4-8-14(9-5-12)26(17,24)25/h2-9H,1H3,(H,19,22)(H2,17,24,25)(H2,18,20,23)
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8.30n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 2121-5 (2005)


Article DOI: 10.1021/jm0494826
BindingDB Entry DOI: 10.7270/Q25X275C
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM12139
PNG
(4-(N-(4-ethyloxycarbonylphenyl)aminocarbonyl-hydra...)
Show SMILES CCOC(=O)c1ccc(NC(=O)NNC(=O)c2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C17H18N4O6S/c1-2-27-16(23)12-3-7-13(8-4-12)19-17(24)21-20-15(22)11-5-9-14(10-6-11)28(18,25)26/h3-10H,2H2,1H3,(H,20,22)(H2,18,25,26)(H2,19,21,24)
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8.5n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 2121-5 (2005)


Article DOI: 10.1021/jm0494826
BindingDB Entry DOI: 10.7270/Q25X275C
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM12141
PNG
(4-(N-(4-bromophenyl)aminocarbonyl-hydrazinocarbony...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C14H13BrN4O4S/c15-10-3-5-11(6-4-10)17-14(21)19-18-13(20)9-1-7-12(8-2-9)24(16,22)23/h1-8H,(H,18,20)(H2,16,22,23)(H2,17,19,21)
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8.60n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 2121-5 (2005)


Article DOI: 10.1021/jm0494826
BindingDB Entry DOI: 10.7270/Q25X275C
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11045
PNG
(N-(2-chloro-4-sulfamoylphenyl)-3-sulfanylpropanami...)
Show SMILES NS(=O)(=O)c1ccc(NC(=O)CCS)c(Cl)c1
Show InChI InChI=1S/C9H11ClN2O3S2/c10-7-5-6(17(11,14)15)1-2-8(7)12-9(13)3-4-16/h1-2,5,16H,3-4H2,(H,12,13)(H2,11,14,15)
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8.70n/an/an/an/an/an/an/an/a



Istituto di Biostrutture e Bioimmagini-CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 5544-51 (2006)


Article DOI: 10.1021/jm060531j
BindingDB Entry DOI: 10.7270/Q21J9805
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11055
PNG
(CHEMBL214745 | N-[2-(4-sulfamoylphenyl)ethyl]-2-su...)
Show SMILES NS(=O)(=O)c1ccc(CCNC(=O)c2ccccc2S)cc1
Show InChI InChI=1S/C15H16N2O3S2/c16-22(19,20)12-7-5-11(6-8-12)9-10-17-15(18)13-3-1-2-4-14(13)21/h1-8,21H,9-10H2,(H,17,18)(H2,16,19,20)
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9n/an/an/an/an/an/an/an/a



Istituto di Biostrutture e Bioimmagini-CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 5544-51 (2006)


Article DOI: 10.1021/jm060531j
BindingDB Entry DOI: 10.7270/Q21J9805
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM14723
PNG
(1-N-[5-Sulfamoyl-1,3,4-thiadiazol-2-yl-(aminosulfo...)
Show SMILES CCc1cc(cc(CC)[n+]1-c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O)-c1ccccc1
Show InChI InChI=1S/C23H24N5O4S3/c1-3-18-14-17(16-8-6-5-7-9-16)15-19(4-2)28(18)20-10-12-21(13-11-20)35(31,32)27-22-25-26-23(33-22)34(24,29)30/h5-15H,3-4H2,1-2H3,(H,25,27)(H2,24,29,30)/q+1
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9n/an/an/an/an/an/an/an/a



Canadian Institutes of Health Research



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 47: 2337-47 (2004)


Article DOI: 10.1021/jm031079w
BindingDB Entry DOI: 10.7270/Q2DV1H4B
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11053
PNG
(CHEMBL386049 | N-(4-sulfamoylphenyl)-2-sulfanylben...)
Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2ccccc2S)cc1
Show InChI InChI=1S/C13H12N2O3S2/c14-20(17,18)10-7-5-9(6-8-10)15-13(16)11-3-1-2-4-12(11)19/h1-8,19H,(H,15,16)(H2,14,17,18)
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9.10n/an/an/an/an/an/an/an/a



Istituto di Biostrutture e Bioimmagini-CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 5544-51 (2006)


Article DOI: 10.1021/jm060531j
BindingDB Entry DOI: 10.7270/Q21J9805
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11050
PNG
(N-[(2E)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thi...)
Show SMILES Cn1nc(sc1=NC(=O)CCSSCCC(=O)N=c1sc(nn1C)S(N)(=O)=O)S(N)(=O)=O
Show InChI InChI=1S/C12H18N8O6S6/c1-19-9(29-11(17-19)31(13,23)24)15-7(21)3-5-27-28-6-4-8(22)16-10-20(2)18-12(30-10)32(14,25)26/h3-6H2,1-2H3,(H2,13,23,24)(H2,14,25,26)
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9.30n/an/an/an/an/an/an/an/a



Istituto di Biostrutture e Bioimmagini-CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 5544-51 (2006)


Article DOI: 10.1021/jm060531j
BindingDB Entry DOI: 10.7270/Q21J9805
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM15224
PNG
(4-(4-{[(2,3,4,6-tetra-O-acetyl-beta-D-galactopyran...)
Show SMILES CC(=O)OC[C@H]1O[C@@H](OCc2cn(nn2)-c2ccc(cc2)S(N)(=O)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O
Show InChI InChI=1S/C23H28N4O12S/c1-12(28)34-11-19-20(36-13(2)29)21(37-14(3)30)22(38-15(4)31)23(39-19)35-10-16-9-27(26-25-16)17-5-7-18(8-6-17)40(24,32)33/h5-9,19-23H,10-11H2,1-4H3,(H2,24,32,33)/t19-,20+,21+,22-,23-/m1/s1
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9.70n/an/an/an/an/an/an/an/a



Griffith University



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 50: 1651-7 (2007)


Article DOI: 10.1021/jm061320h
BindingDB Entry DOI: 10.7270/Q2668BFJ
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11605
PNG
(β-CA inhibitor, 4 | 4-Amino-5-chloro-3-fluoro...)
Show SMILES Nc1c(F)cc(cc1Cl)S(N)(=O)=O
Show InChI InChI=1S/C6H6ClFN2O2S/c7-4-1-3(13(10,11)12)2-5(8)6(4)9/h1-2H,9H2,(H2,10,11,12)
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12n/an/an/an/an/an/an/an/a



University of Agricultural Sciences and Veterinary Medicine



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 46: 2187-96 (2003)


Article DOI: 10.1021/jm021123s
BindingDB Entry DOI: 10.7270/Q2XK8CR9
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM14734
PNG
(1-N-[5-Sulfamoyl-1,3,4-thiadiazol-2-yl-(aminosulfo...)
Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(cc2)-[n+]2c(cc(cc2-c2ccccc2)-c2ccccc2)-c2ccccc2)s1
Show InChI InChI=1S/C31H24N5O4S3/c32-42(37,38)31-34-33-30(41-31)35-43(39,40)27-18-16-26(17-19-27)36-28(23-12-6-2-7-13-23)20-25(22-10-4-1-5-11-22)21-29(36)24-14-8-3-9-15-24/h1-21H,(H,33,35)(H2,32,37,38)/q+1
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12n/an/an/an/an/an/an/an/a



Canadian Institutes of Health Research



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 47: 2337-47 (2004)


Article DOI: 10.1021/jm031079w
BindingDB Entry DOI: 10.7270/Q2DV1H4B
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM14733
PNG
(4-methyl-2,6-diphenyl-1-{4-[(5-sulfamoyl-1,3,4-thi...)
Show SMILES Cc1cc(-c2ccccc2)[n+](-c2ccc(cc2)S(=O)(=O)Nc2nnc(s2)S(N)(=O)=O)c(c1)-c1ccccc1
Show InChI InChI=1S/C26H22N5O4S3/c1-18-16-23(19-8-4-2-5-9-19)31(24(17-18)20-10-6-3-7-11-20)21-12-14-22(15-13-21)38(34,35)30-25-28-29-26(36-25)37(27,32)33/h2-17H,1H3,(H,28,30)(H2,27,32,33)/q+1
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12n/an/an/an/an/an/an/an/a



Canadian Institutes of Health Research



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 47: 2337-47 (2004)


Article DOI: 10.1021/jm031079w
BindingDB Entry DOI: 10.7270/Q2DV1H4B
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM12146
PNG
(2-[4-(aminosulfonyl)benzoyl]-N-9H-fluoren-9-ylhydr...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)NC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C21H18N4O4S/c22-30(28,29)14-11-9-13(10-12-14)20(26)24-25-21(27)23-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-12,19H,(H,24,26)(H2,22,28,29)(H2,23,25,27)
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13n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 2121-5 (2005)


Article DOI: 10.1021/jm0494826
BindingDB Entry DOI: 10.7270/Q25X275C
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11641
PNG
(1-N-(4-sulfamoylphenyl-ethyl)-2,4,6-trimethylpyrid...)
Show SMILES Cc1cc(C)[n+](CCc2ccc(cc2)S(N)(=O)=O)c(C)c1
Show InChI InChI=1S/C16H21N2O2S/c1-12-10-13(2)18(14(3)11-12)9-8-15-4-6-16(7-5-15)21(17,19)20/h4-7,10-11H,8-9H2,1-3H3,(H2,17,19,20)/q+1
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14 -10.6n/an/an/an/an/a7.522



Istituto di Biostrutture e Bioimmagini-CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 5721-7 (2005)


Article DOI: 10.1021/jm050333c
BindingDB Entry DOI: 10.7270/Q2ST7N2F
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11043
PNG
(N-(2-fluoro-4-sulfamoylphenyl)-3-sulfanylpropanami...)
Show SMILES NS(=O)(=O)c1ccc(NC(=O)CCS)c(F)c1
Show InChI InChI=1S/C9H11FN2O3S2/c10-7-5-6(17(11,14)15)1-2-8(7)12-9(13)3-4-16/h1-2,5,16H,3-4H2,(H,12,13)(H2,11,14,15)
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15n/an/an/an/an/an/an/an/a



Istituto di Biostrutture e Bioimmagini-CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 5544-51 (2006)


Article DOI: 10.1021/jm060531j
BindingDB Entry DOI: 10.7270/Q21J9805
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM14737
PNG
(2,3,6-trimethyl-4-phenyl-1-{4-[(5-sulfamoyl-1,3,4-...)
Show SMILES Cc1cc(c(C)c(C)[n+]1-c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O)-c1ccccc1
Show InChI InChI=1S/C22H22N5O4S3/c1-14-13-20(17-7-5-4-6-8-17)15(2)16(3)27(14)18-9-11-19(12-10-18)34(30,31)26-21-24-25-22(32-21)33(23,28)29/h4-13H,1-3H3,(H,24,26)(H2,23,28,29)/q+1
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15n/an/an/an/an/an/an/an/a



Canadian Institutes of Health Research



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 47: 2337-47 (2004)


Article DOI: 10.1021/jm031079w
BindingDB Entry DOI: 10.7270/Q2DV1H4B
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11640
PNG
(3-[(2,3,4,5,6-pentafluorophenyl)amino]-1-(4-sulfam...)
Show SMILES NS(=O)(=O)c1ccc(NC(=S)NNc2c(F)c(F)c(F)c(F)c2F)cc1
Show InChI InChI=1S/C13H9F5N4O2S2/c14-7-8(15)10(17)12(11(18)9(7)16)21-22-13(25)20-5-1-3-6(4-2-5)26(19,23)24/h1-4,21H,(H2,19,23,24)(H2,20,22,25)
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15 -10.6n/an/an/an/an/a7.522



Istituto di Biostrutture e Bioimmagini-CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 5721-7 (2005)


Article DOI: 10.1021/jm050333c
BindingDB Entry DOI: 10.7270/Q2ST7N2F
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11636
PNG
(CHEMBL309431 | N-[2-(diethylamino)ethyl]-4-[(5-sul...)
Show SMILES CCN(CC)CCNC(=O)c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C15H22N6O5S3/c1-3-21(4-2)10-9-17-13(22)11-5-7-12(8-6-11)29(25,26)20-14-18-19-15(27-14)28(16,23)24/h5-8H,3-4,9-10H2,1-2H3,(H,17,22)(H,18,20)(H2,16,23,24)
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16 -10.5n/an/an/an/an/a7.522



Istituto di Biostrutture e Bioimmagini-CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 5721-7 (2005)


Article DOI: 10.1021/jm050333c
BindingDB Entry DOI: 10.7270/Q2ST7N2F
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM14735
PNG
(1-N-[5-Sulfamoyl-1,3,4-thiadiazol-2-yl-(aminosulfo...)
Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(cc2)-[n+]2c(cccc2-c2ccccc2)-c2ccccc2)s1
Show InChI InChI=1S/C25H20N5O4S3/c26-36(31,32)25-28-27-24(35-25)29-37(33,34)21-16-14-20(15-17-21)30-22(18-8-3-1-4-9-18)12-7-13-23(30)19-10-5-2-6-11-19/h1-17H,(H,27,29)(H2,26,31,32)/q+1
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16n/an/an/an/an/an/an/an/a



Canadian Institutes of Health Research



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 47: 2337-47 (2004)


Article DOI: 10.1021/jm031079w
BindingDB Entry DOI: 10.7270/Q2DV1H4B
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM14720
PNG
(1-N-[5-Sulfamoyl-1,3,4-thiadiazol-2-yl-(aminosulfo...)
Show SMILES CC(C)c1cc(C)cc(C(C)C)[n+]1-c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C20H26N5O4S3/c1-12(2)17-10-14(5)11-18(13(3)4)25(17)15-6-8-16(9-7-15)32(28,29)24-19-22-23-20(30-19)31(21,26)27/h6-13H,1-5H3,(H,22,24)(H2,21,26,27)/q+1
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16n/an/an/an/an/an/an/an/a



Canadian Institutes of Health Research



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 47: 2337-47 (2004)


Article DOI: 10.1021/jm031079w
BindingDB Entry DOI: 10.7270/Q2DV1H4B
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM11639
PNG
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
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16 -10.5n/an/an/an/an/a7.522



Istituto di Biostrutture e Bioimmagini-CNR



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 48: 5721-7 (2005)


Article DOI: 10.1021/jm050333c
BindingDB Entry DOI: 10.7270/Q2ST7N2F
More data for this
Ligand-Target Pair
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