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Compile Data Set for Download or QSAR

Found 5 hits of Enz. Inhib. data with enzyme = 'Colony stimulating factor 1 receptor' and Substrate = 'to-be-curated'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Colony stimulating factor 1 receptor


(Canis lupus familiaris (Dog) (Canis familiaris))
BDBM276744
PNG
(US10071991, Compound (I-M2-2S,4R))
Show SMILES CC1(C)CCC(=CC1)c1nc(ccc1NC(=O)c1nc(c[nH]1)C#N)[C@@H]1CC(C)(C)O[C@@](C)(C1)C(O)=O
Show InChI InChI=1S/C27H33N5O4/c1-25(2)10-8-16(9-11-25)21-20(32-23(33)22-29-15-18(14-28)30-22)7-6-19(31-21)17-12-26(3,4)36-27(5,13-17)24(34)35/h6-8,15,17H,9-13H2,1-5H3,(H,29,30)(H,32,33)(H,34,35)/t17-,27+/m1/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/a7.025



Janssen Pharmaceutica NV

US Patent


Assay Description
In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...


US Patent US10071991 (2018)

More data for this
Ligand-Target Pair
Colony stimulating factor 1 receptor


(Canis lupus familiaris (Dog) (Canis familiaris))
BDBM276745
PNG
(US10071991, Compound (I-M2-2R,4S))
Show SMILES CC1(C)CCC(=CC1)c1nc(ccc1NC(=O)c1nc(c[nH]1)C#N)[C@H]1CC(C)(C)O[C@](C)(C1)C(O)=O
Show InChI InChI=1S/C27H33N5O4/c1-25(2)10-8-16(9-11-25)21-20(32-23(33)22-29-15-18(14-28)30-22)7-6-19(31-21)17-12-26(3,4)36-27(5,13-17)24(34)35/h6-8,15,17H,9-13H2,1-5H3,(H,29,30)(H,32,33)(H,34,35)/t17-,27+/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/a7.025



Janssen Pharmaceutica NV

US Patent


Assay Description
In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...


US Patent US10071991 (2018)

More data for this
Ligand-Target Pair
Colony stimulating factor 1 receptor


(Canis lupus familiaris (Dog) (Canis familiaris))
BDBM276746
PNG
(US10071991, Compound (I-M7-2S,4R))
Show SMILES CC1(C)CCC(=CC1)c1nc(ccc1NC(=O)c1nc(c[nH]1)C#N)[C@@H]1CC(C)(C)O[C@](C)(CO)C1
Show InChI InChI=1S/C27H35N5O3/c1-25(2)10-8-17(9-11-25)22-21(32-24(34)23-29-15-19(14-28)30-23)7-6-20(31-22)18-12-26(3,4)35-27(5,13-18)16-33/h6-8,15,18,33H,9-13,16H2,1-5H3,(H,29,30)(H,32,34)/t18-,27+/m1/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.60n/an/an/an/a7.025



Janssen Pharmaceutica NV

US Patent


Assay Description
In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...


US Patent US10071991 (2018)

More data for this
Ligand-Target Pair
Colony stimulating factor 1 receptor


(Canis lupus familiaris (Dog) (Canis familiaris))
BDBM276747
PNG
(US10071991, Compound (I-M7-2R,4S))
Show SMILES CC1(C)CCC(=CC1)c1nc(ccc1NC(=O)c1nc(c[nH]1)C#N)[C@H]1CC(C)(C)O[C@](C)(CO)C1
Show InChI InChI=1S/C27H35N5O3/c1-25(2)10-8-17(9-11-25)22-21(32-24(34)23-29-15-19(14-28)30-23)7-6-20(31-22)18-12-26(3,4)35-27(5,13-18)16-33/h6-8,15,18,33H,9-13,16H2,1-5H3,(H,29,30)(H,32,34)/t18-,27-/m0/s1
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8n/an/an/an/a7.025



Janssen Pharmaceutica NV

US Patent


Assay Description
In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...


US Patent US10071991 (2018)

More data for this
Ligand-Target Pair
Colony stimulating factor 1 receptor


(Canis lupus familiaris (Dog) (Canis familiaris))
BDBM276743
PNG
(US10071991, Compound (P) | US9611259, Compound (P))
Show SMILES CC1(C)CCC(=CC1)c1nc(ccc1NC(=O)c1nc(c[nH]1)C#N)C1CC(C)(C)OC(C)(C)C1
Show InChI InChI=1S/C27H35N5O2/c1-25(2)11-9-17(10-12-25)22-21(32-24(33)23-29-16-19(15-28)30-23)8-7-20(31-22)18-13-26(3,4)34-27(5,6)14-18/h7-9,16,18H,10-14H2,1-6H3,(H,29,30)(H,32,33)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 16n/an/an/an/a7.025



Janssen Pharmaceutica NV

US Patent


Assay Description
In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...


US Patent US10071991 (2018)

More data for this
Ligand-Target Pair