Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-Dependent Kinase 2 (CDK2) Mutant (L83V/H84D) (Homo sapiens (human)) | BDBM5544![]() (4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benz...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet ![]() | MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Oxford | Assay Description In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 12.5 uM ATP/ [ga... | J Med Chem 49: 5470-7 (2006) Article DOI: 10.1021/jm060216x BindingDB Entry DOI: 10.7270/Q2TQ5ZS3 | |||||||||||
More data for this Ligand-Target Pair |