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Compile Data Set for Download or QSAR

Found 1 hit of Enz. Inhib. data with enzyme = 'Cytosolic phosphoenolpyruvate carboxykinase (cPEPCK)' and Substrate = 'BDBM181110'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytosolic phosphoenolpyruvate carboxykinase (cPEPCK)


(Rattus norvegicus (Rat))
BDBM181109
PNG
(3-Mercaptopicolinic acid (MPA))
Show SMILES OC(=O)c1ncccc1S
Show InChI InChI=1S/C6H5NO2S/c8-6(9)5-4(10)2-1-3-7-5/h1-3,10H,(H,8,9)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
1.21E+5 -5.34n/an/an/an/an/an/a25



The University of Kansas Medical Center



Assay Description
Allosteric binding site. The activity of PEPCK in the direction from OAA to PEP was assayed with 50 mM HEPES (pH 7.5), 10 mM DTT, 4 mM MgCl2, 0.5 mM ...


Biochemistry 54: 5878-87 (2015)


Article DOI: 10.1021/acs.biochem.5b00822
BindingDB Entry DOI: 10.7270/Q2M61J1Q
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)