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Found 5 hits of Enz. Inhib. data with enzyme = 'Dengue Virus 2 (DENV2) NS2B-NS3 Protease' and Substrate = 'BDBM33263'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dengue Virus 2 (DENV2) NS2B-NS3 Protease


(Dengue virus 2 (strain TSV01))
BDBM33265
PNG
(guanidine, 5)
Show SMILES Cc1ccc(cc1)C(=NN=C(N)N)P(O)O
Show InChI InChI=1S/C9H13N4O2P/c1-6-2-4-7(5-3-6)8(16(14)15)12-13-9(10)11/h2-5,14-15H,1H3,(H4,10,11,13)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
1.40E+4 -6.57n/an/an/an/an/a8.523



University of Alabama at Birmingham



Assay Description
All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...


Bioorg Med Chem 13: 257-64 (2005)


Article DOI: 10.1016/j.bmc.2004.09.036
BindingDB Entry DOI: 10.7270/Q2QV3JVQ
More data for this
Ligand-Target Pair
Dengue Virus 2 (DENV2) NS2B-NS3 Protease


(Dengue virus 2 (strain TSV01))
BDBM33264
PNG
(guanidine, 4)
Show SMILES NC(N)=NN=C1C(=O)Nc2ccccc12
Show InChI InChI=1S/C9H9N5O/c10-9(11)14-13-7-5-3-1-2-4-6(5)12-8(7)15/h1-4H,(H4,10,11,14)(H,12,13,15)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
2.30E+4 -6.28n/an/an/an/an/a8.523



University of Alabama at Birmingham



Assay Description
All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...


Bioorg Med Chem 13: 257-64 (2005)


Article DOI: 10.1016/j.bmc.2004.09.036
BindingDB Entry DOI: 10.7270/Q2QV3JVQ
More data for this
Ligand-Target Pair
Dengue Virus 2 (DENV2) NS2B-NS3 Protease


(Dengue virus 2 (strain TSV01))
BDBM33261
PNG
(biguanidine, 1)
Show SMILES NC(N)=NN=Cc1ccc(C=NN=C(N)N)cc1
Show InChI InChI=1S/C10H14N8/c11-9(12)17-15-5-7-1-2-8(4-3-7)6-16-18-10(13)14/h1-6H,(H4,11,12,17)(H4,13,14,18)
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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4.40E+4 -5.90n/an/an/an/an/a8.523



University of Alabama at Birmingham



Assay Description
All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...


Bioorg Med Chem 13: 257-64 (2005)


Article DOI: 10.1016/j.bmc.2004.09.036
BindingDB Entry DOI: 10.7270/Q2QV3JVQ
More data for this
Ligand-Target Pair
Dengue Virus 2 (DENV2) NS2B-NS3 Protease


(Dengue virus 2 (strain TSV01))
BDBM33260
PNG
(biguanidine, 2)
Show SMILES NC(=N)NN=CC=NN=C(N)N
Show InChI InChI=1S/C4H10N8/c5-3(6)11-9-1-2-10-12-4(7)8/h1-2H,(H4,5,6,11)(H4,7,8,12)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
4.23E+5 -4.57n/an/an/an/an/a8.523



University of Alabama at Birmingham



Assay Description
All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...


Bioorg Med Chem 13: 257-64 (2005)


Article DOI: 10.1016/j.bmc.2004.09.036
BindingDB Entry DOI: 10.7270/Q2QV3JVQ
More data for this
Ligand-Target Pair
Dengue Virus 2 (DENV2) NS2B-NS3 Protease


(Dengue virus 2 (strain TSV01))
BDBM33262
PNG
(biguanidine, 3)
Show SMILES NC(N)NNc1ccc(NN=C(N)N)cc1
Show InChI InChI=1S/C8H16N8/c9-7(10)15-13-5-1-2-6(4-3-5)14-16-8(11)12/h1-4,7,13-15H,9-10H2,(H4,11,12,16)
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MMDB

B.MOAD
GoogleScholar
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PC cid
PC sid
UniChem

Patents

Article
PubMed
1.78E+6 -3.72n/an/an/an/an/a8.523



University of Alabama at Birmingham



Assay Description
All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...


Bioorg Med Chem 13: 257-64 (2005)


Article DOI: 10.1016/j.bmc.2004.09.036
BindingDB Entry DOI: 10.7270/Q2QV3JVQ
More data for this
Ligand-Target Pair