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Compile Data Set for Download or QSAR

Found 1 hit of Enz. Inhib. data with enzyme = 'Dual specificity mitogen-activated protein kinase kinase 1' and Substrate = 'myelin basic protein'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual specificity mitogen-activated protein kinase kinase 1


(Homo sapiens (human))
BDBM28044
PNG
(7-amino-4-(3-phenylphenyl)thieno[2,3-c]pyridine-2-...)
Show SMILES NC(=O)c1cc2c(cnc(N)c2s1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C20H15N3OS/c21-19-18-15(10-17(25-18)20(22)24)16(11-23-19)14-8-4-7-13(9-14)12-5-2-1-3-6-12/h1-11H,(H2,21,23)(H2,22,24)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.30E+4n/an/an/an/a7.522



Abbott Laboratories



Assay Description
MEK1 cascade HTRF assays were carried out using inactive Erk2 as a downstream kinase with biotin-MBP protein as the final substrate. The reaction was...


Bioorg Med Chem Lett 19: 1722-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.088
BindingDB Entry DOI: 10.7270/Q2VH5M4P
More data for this
Ligand-Target Pair