Compile Data Set for Download or QSAR

Found 24 hits of Enz. Inhib. data with enzyme = 'Epidermal growth factor receptor' and Substrate = 'Poly(Glu,Tyr)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13911 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(O)=O Show InChI InChI=1S/C23H20N6O2/c1-2-18-19(23(30)31)13-29-21(18)22(24-14-26-29)27-17-8-9-20-16(10-17)11-25-28(20)12-15-6-4-3-5-7-15/h3-11,13-14H,2,12H2,1H3,(H,30,31)(H,24,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13921 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-[3-(...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)NCCCn1ccnc1 Show InChI InChI=1S/C29H29N9O/c1-2-24-25(29(39)31-11-6-13-36-14-12-30-20-36)18-38-27(24)28(32-19-34-38)35-23-9-10-26-22(15-23)16-33-37(26)17-21-7-4-3-5-8-21/h3-5,7-10,12,14-16,18-20H,2,6,11,13,17H2,1H3,(H,31,39)(H,32,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13923 (2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...) Show SMILES CCc1c(NC(=O)OCCn2ccnc2)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12 Show InChI InChI=1S/C28H27N9O2/c1-2-23-24(34-28(38)39-13-12-35-11-10-29-19-35)17-37-26(23)27(30-18-32-37)33-22-8-9-25-21(14-22)15-31-36(25)16-20-6-4-3-5-7-20/h3-11,14-15,17-19H,2,12-13,16H2,1H3,(H,34,38)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13902 (CHEMBL372112 | ethyl 5-ethyl-4-(1H-indazol-5-ylami...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4[nH]ncc4c3)c2c1CC Show InChI InChI=1S/C18H18N6O2/c1-3-13-14(18(25)26-4-2)9-24-16(13)17(19-10-21-24)22-12-5-6-15-11(7-12)8-20-23-15/h5-10H,3-4H2,1-2H3,(H,20,23)(H,19,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13901 (CHEMBL370934 | ethyl 4-[(3-bromophenyl)amino]-5-et...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3cccc(Br)c3)c2c1CC Show InChI InChI=1S/C17H17BrN4O2/c1-3-13-14(17(23)24-4-2)9-22-15(13)16(19-10-20-22)21-12-7-5-6-11(18)8-12/h5-10H,3-4H2,1-2H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13913 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-meth...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)NC Show InChI InChI=1S/C24H23N7O/c1-3-19-20(24(32)25-2)14-31-22(19)23(26-15-28-31)29-18-9-10-21-17(11-18)12-27-30(21)13-16-7-5-4-6-8-16/h4-12,14-15H,3,13H2,1-2H3,(H,25,32)(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13900 (CHEMBL196018 | ethyl 4-[(3-chloro-4-fluorophenyl)a...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc(F)c(Cl)c3)c2c1CC Show InChI InChI=1S/C17H16ClFN4O2/c1-3-11-12(17(24)25-4-2)8-23-15(11)16(20-9-21-23)22-10-5-6-14(19)13(18)7-10/h5-9H,3-4H2,1-2H3,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13904 (CHEMBL196925 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1CC Show InChI InChI=1S/C25H24N6O2/c1-3-20-21(25(32)33-4-2)15-31-23(20)24(26-16-28-31)29-19-10-11-22-18(12-19)13-27-30(22)14-17-8-6-5-7-9-17/h5-13,15-16H,3-4,14H2,1-2H3,(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13906 (CHEMBL425738 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnn2c1 Show InChI InChI=1S/C23H20N6O2/c1-2-31-23(30)18-11-21-22(24-15-26-29(21)14-18)27-19-8-9-20-17(10-19)12-25-28(20)13-16-6-4-3-5-7-16/h3-12,14-15H,2,13H2,1H3,(H,24,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13912 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(N)=O Show InChI InChI=1S/C23H21N7O/c1-2-18-19(22(24)31)13-30-21(18)23(25-14-27-30)28-17-8-9-20-16(10-17)11-26-29(20)12-15-6-4-3-5-7-15/h3-11,13-14H,2,12H2,1H3,(H2,24,31)(H,25,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13922 (3-(1H-imidazol-1-yl)propyl 4-[(1-benzyl-1H-indazol...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)OCCCn1ccnc1 Show InChI InChI=1S/C29H28N8O2/c1-2-24-25(29(38)39-14-6-12-35-13-11-30-20-35)18-37-27(24)28(31-19-33-37)34-23-9-10-26-22(15-23)16-32-36(26)17-21-7-4-3-5-8-21/h3-5,7-11,13,15-16,18-20H,2,6,12,14,17H2,1H3,(H,31,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13903 (ethyl 5-ethyl-4-{[(1R)-1-phenylethyl]amino}pyrrolo...) Show SMILES CCOC(=O)c1cn2ncnc(N[C@H](C)c3ccccc3)c2c1CC Show InChI InChI=1S/C19H22N4O2/c1-4-15-16(19(24)25-5-2)11-23-17(15)18(20-12-21-23)22-13(3)14-9-7-6-8-10-14/h6-13H,4-5H2,1-3H3,(H,20,21,22)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13907 (CHEMBL196738 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1C Show InChI InChI=1S/C24H22N6O2/c1-3-32-24(31)20-14-30-22(16(20)2)23(25-15-27-30)28-19-9-10-21-18(11-19)12-26-29(21)13-17-7-5-4-6-8-17/h4-12,14-15H,3,13H2,1-2H3,(H,25,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13908 (CHEMBL365606 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1C(C)C Show InChI InChI=1S/C26H26N6O2/c1-4-34-26(33)21-15-32-24(23(21)17(2)3)25(27-16-29-32)30-20-10-11-22-19(12-20)13-28-31(22)14-18-8-6-5-7-9-18/h5-13,15-17H,4,14H2,1-3H3,(H,27,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13914 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N,N-di...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)N(C)C Show InChI InChI=1S/C25H25N7O/c1-4-20-21(25(33)30(2)3)15-32-23(20)24(26-16-28-32)29-19-10-11-22-18(12-19)13-27-31(22)14-17-8-6-5-7-9-17/h5-13,15-16H,4,14H2,1-3H3,(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13915 (CHEMBL372523 | benzyl N-{4-[(1-benzyl-1H-indazol-5...) Show SMILES CCc1c(NC(=O)OCc2ccccc2)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12 Show InChI InChI=1S/C30H27N7O2/c1-2-25-26(35-30(38)39-19-22-11-7-4-8-12-22)18-37-28(25)29(31-20-33-37)34-24-13-14-27-23(15-24)16-32-36(27)17-21-9-5-3-6-10-21/h3-16,18,20H,2,17,19H2,1H3,(H,35,38)(H,31,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13916 (CHEMBL373025 | pyrrolo[2,1-f][1,2,4]triazine analo...) Show SMILES CCc1c(CO)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12 Show InChI InChI=1S/C23H22N6O/c1-2-20-18(14-30)13-29-22(20)23(24-15-26-29)27-19-8-9-21-17(10-19)11-25-28(21)12-16-6-4-3-5-7-16/h3-11,13,15,30H,2,12,14H2,1H3,(H,24,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13905 (CHEMBL194349 | ethyl 5-ethyl-4-[(4-phenoxyphenyl)a...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2c1CC Show InChI InChI=1S/C23H22N4O3/c1-3-19-20(23(28)29-4-2)14-27-21(19)22(24-15-25-27)26-16-10-12-18(13-11-16)30-17-8-6-5-7-9-17/h5-15H,3-4H2,1-2H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13918 (1-benzyl-N-[6-(ethoxymethyl)-5-ethylpyrrolo[1,2-a]...) Show SMILES CCOCc1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1CC Show InChI InChI=1S/C25H26N6O/c1-3-22-20(16-32-4-2)15-31-24(22)25(26-17-28-31)29-21-10-11-23-19(12-21)13-27-30(23)14-18-8-6-5-7-9-18/h5-13,15,17H,3-4,14,16H2,1-2H3,(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13909 (CHEMBL438805 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)OCC Show InChI InChI=1S/C26H26N6O2/c1-3-8-21-22(26(33)34-4-2)16-32-24(21)25(27-17-29-32)30-20-11-12-23-19(13-20)14-28-31(23)15-18-9-6-5-7-10-18/h5-7,9-14,16-17H,3-4,8,15H2,1-2H3,(H,27,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13919 (2-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrr...) Show SMILES CCc1c(CC(N)=O)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12 Show InChI InChI=1S/C24H23N7O/c1-2-20-18(11-22(25)32)14-31-23(20)24(26-15-28-31)29-19-8-9-21-17(10-19)12-27-30(21)13-16-6-4-3-5-7-16/h3-10,12,14-15H,2,11,13H2,1H3,(H2,25,32)(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13920 (2-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrr...) Show SMILES CCc1c(CC(O)=O)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12 Show InChI InChI=1S/C24H22N6O2/c1-2-20-18(11-22(31)32)14-30-23(20)24(25-15-27-30)28-19-8-9-21-17(10-19)12-26-29(21)13-16-6-4-3-5-7-16/h3-10,12,14-15H,2,11,13H2,1H3,(H,31,32)(H,25,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13917 (1-benzyl-N-{5-ethyl-6-[(ethylamino)methyl]pyrrolo[...) Show SMILES CCNCc1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1CC Show InChI InChI=1S/C25H27N7/c1-3-22-20(13-26-4-2)16-32-24(22)25(27-17-29-32)30-21-10-11-23-19(12-21)14-28-31(23)15-18-8-6-5-7-9-18/h5-12,14,16-17,26H,3-4,13,15H2,1-2H3,(H,27,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (human))	BDBM13910 (CHEMBL197568 | ethyl 5-benzyl-4-[(1-benzyl-1H-inda...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1Cc1ccccc1 Show InChI InChI=1S/C30H26N6O2/c1-2-38-30(37)26-19-36-28(25(26)15-21-9-5-3-6-10-21)29(31-20-33-36)34-24-13-14-27-23(16-24)17-32-35(27)18-22-11-7-4-8-12-22/h3-14,16-17,19-20H,2,15,18H2,1H3,(H,31,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair