BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 101 hits from AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250432
PNG
(US9464044, 22)
Show SMILES CN(CC1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C23H30FN3O4S/c1-27(32(30,31)18-5-3-2-4-17(18)24)13-22(6-7-22)21(29)26-19-15-8-14-9-16(19)12-23(10-14,11-15)20(25)28/h2-5,14-16,19H,6-13H2,1H3,(H2,25,28)(H,26,29)/t14?,15?,16?,19-,23?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0200n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250460
PNG
(US9464044, 62)
Show SMILES CN(C1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O)S(=O)(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C22H28ClN3O4S/c1-26(31(29,30)17-4-2-3-16(23)9-17)22(5-6-22)20(28)25-18-14-7-13-8-15(18)12-21(10-13,11-14)19(24)27/h2-4,9,13-15,18H,5-8,10-12H2,1H3,(H2,24,27)(H,25,28)/t13?,14?,15?,18-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.120n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250418
PNG
(US9464044, 8)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CNS(=O)(=O)c4cccc(Cl)c4F)CC1)C(C3)C2
Show InChI InChI=1S/C22H27ClFN3O4S/c23-15-2-1-3-16(17(15)24)32(30,31)26-11-21(4-5-21)20(29)27-18-13-6-12-7-14(18)10-22(8-12,9-13)19(25)28/h1-3,12-14,18,26H,4-11H2,(H2,25,28)(H,27,29)/t12?,13?,14?,18-,22?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.300n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM50112152
PNG
(CHEMBL3608401 | US9464044, 84)
Show SMILES CC(C)(NS(=O)(=O)c1c(F)cccc1F)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C21H27F2N3O4S/c1-20(2,26-31(29,30)17-14(22)4-3-5-15(17)23)19(28)25-16-12-6-11-7-13(16)10-21(8-11,9-12)18(24)27/h3-5,11-13,16,26H,6-10H2,1-2H3,(H2,24,27)(H,25,28)/t11?,12?,13?,16-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 0.360n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250453
PNG
(US9464044, 50)
Show SMILES Cn1ccc2cccc(c12)S(=O)(=O)NC1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C24H30N4O4S/c1-28-8-5-15-3-2-4-18(20(15)28)33(31,32)27-24(6-7-24)22(30)26-19-16-9-14-10-17(19)13-23(11-14,12-16)21(25)29/h2-5,8,14,16-17,19,27H,6-7,9-13H2,1H3,(H2,25,29)(H,26,30)/t14?,16?,17?,19-,23?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.400n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM50112133
PNG
(CHEMBL3609861 | US9464044, 71)
Show SMILES CC(C)(NS(=O)(=O)c1ccccc1F)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C21H28FN3O4S/c1-20(2,25-30(28,29)16-6-4-3-5-15(16)22)19(27)24-17-13-7-12-8-14(17)11-21(9-12,10-13)18(23)26/h3-6,12-14,17,25H,7-11H2,1-2H3,(H2,23,26)(H,24,27)/t12?,13?,14?,17-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 0.600n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM50112143
PNG
(CHEMBL3609871 | US9464044, 73)
Show SMILES CC(C)(NS(=O)(=O)c1cccc(Cl)c1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C21H28ClN3O4S/c1-20(2,25-30(28,29)16-5-3-4-15(22)8-16)19(27)24-17-13-6-12-7-14(17)11-21(9-12,10-13)18(23)26/h3-5,8,12-14,17,25H,6-7,9-11H2,1-2H3,(H2,23,26)(H,24,27)/t12?,13?,14?,17-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 0.830n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250486
PNG
(US9464044, 119)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)c1cccc(NS(=O)(=O)c4cc(Cl)cc(Cl)c4)c1)C(C3)C2
Show InChI InChI=1S/C24H25Cl2N3O4S/c25-17-7-18(26)9-20(8-17)34(32,33)29-19-3-1-2-14(6-19)22(30)28-21-15-4-13-5-16(21)12-24(10-13,11-15)23(27)31/h1-3,6-9,13,15-16,21,29H,4-5,10-12H2,(H2,27,31)(H,28,30)/t13?,15?,16?,21-,24?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.900n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250474
PNG
(US9464044, 102)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)c1cccc(NS(=O)(=O)c4cccs4)c1)C(C3)C2
Show InChI InChI=1S/C22H25N3O4S2/c23-21(27)22-10-13-7-15(11-22)19(16(8-13)12-22)24-20(26)14-3-1-4-17(9-14)25-31(28,29)18-5-2-6-30-18/h1-6,9,13,15-16,19,25H,7-8,10-12H2,(H2,23,27)(H,24,26)/t13?,15?,16?,19-,22?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.10n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250436
PNG
(US9464044, 28)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CNS(=O)(=O)c4ccccc4)CC1)C(C3)C2
Show InChI InChI=1S/C22H29N3O4S/c23-19(26)22-10-14-8-15(11-22)18(16(9-14)12-22)25-20(27)21(6-7-21)13-24-30(28,29)17-4-2-1-3-5-17/h1-5,14-16,18,24H,6-13H2,(H2,23,26)(H,25,27)/t14?,15?,16?,18-,22?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.20n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250466
PNG
(US9464044, 72)
Show SMILES CN(C(C)(C)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C22H30FN3O4S/c1-21(2,26(3)31(29,30)17-7-5-4-6-16(17)23)20(28)25-18-14-8-13-9-15(18)12-22(10-13,11-14)19(24)27/h4-7,13-15,18H,8-12H2,1-3H3,(H2,24,27)(H,25,28)/t13?,14?,15?,18-,22?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.20n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250435
PNG
(US9464044, 26)
Show SMILES Cn1ccc2cc(ccc12)S(=O)(=O)NCC1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C25H32N4O4S/c1-29-7-4-16-10-19(2-3-20(16)29)34(32,33)27-14-24(5-6-24)23(31)28-21-17-8-15-9-18(21)13-25(11-15,12-17)22(26)30/h2-4,7,10,15,17-18,21,27H,5-6,8-9,11-14H2,1H3,(H2,26,30)(H,28,31)/t15?,17?,18?,21-,25?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.20n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250437
PNG
(US9464044, 31)
Show SMILES CN(CC1(CC1)C(=O)NC12CC3CC(CC(C3)C1)C2)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C22H29FN2O3S/c1-25(29(27,28)19-5-3-2-4-18(19)23)14-21(6-7-21)20(26)24-22-11-15-8-16(12-22)10-17(9-15)13-22/h2-5,15-17H,6-14H2,1H3,(H,24,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.20n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250438
PNG
(US9464044, 32)
Show SMILES CCN(CC1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C24H32FN3O4S/c1-2-28(33(31,32)19-6-4-3-5-18(19)25)14-23(7-8-23)22(30)27-20-16-9-15-10-17(20)13-24(11-15,12-16)21(26)29/h3-6,15-17,20H,2,7-14H2,1H3,(H2,26,29)(H,27,30)/t15?,16?,17?,20-,24?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.40n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250439
PNG
(US9464044, 33)
Show SMILES OCCC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CNS(=O)(=O)c4ccccc4F)CC1)C(C3)C2
Show InChI InChI=1S/C24H31FN2O5S/c25-18-3-1-2-4-19(18)33(31,32)26-14-23(6-7-23)22(30)27-21-16-9-15-10-17(21)13-24(11-15,12-16)20(29)5-8-28/h1-4,15-17,21,26,28H,5-14H2,(H,27,30)/t15?,16?,17?,21-,24?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.5n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250444
PNG
(US9464044, 40)
Show SMILES Cc1cccc(F)c1S(=O)(=O)NC1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C22H28FN3O4S/c1-12-3-2-4-16(23)18(12)31(29,30)26-22(5-6-22)20(28)25-17-14-7-13-8-15(17)11-21(9-13,10-14)19(24)27/h2-4,13-15,17,26H,5-11H2,1H3,(H2,24,27)(H,25,28)/t13?,14?,15?,17-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.70n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250472
PNG
(US9464044, 99)
Show SMILES CN(c1cccc(c1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O)S(=O)(=O)c1ccccc1C(F)(F)F
Show InChI InChI=1S/C26H28F3N3O4S/c1-32(37(35,36)21-8-3-2-7-20(21)26(27,28)29)19-6-4-5-16(11-19)23(33)31-22-17-9-15-10-18(22)14-25(12-15,13-17)24(30)34/h2-8,11,15,17-18,22H,9-10,12-14H2,1H3,(H2,30,34)(H,31,33)/t15?,17?,18?,22-,25?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.90n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM50112142
PNG
(CHEMBL3609870 | US9464044, 81)
Show SMILES CC(C)(NS(=O)(=O)c1ccccc1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C21H29N3O4S/c1-20(2,24-29(27,28)16-6-4-3-5-7-16)19(26)23-17-14-8-13-9-15(17)12-21(10-13,11-14)18(22)25/h3-7,13-15,17,24H,8-12H2,1-2H3,(H2,22,25)(H,23,26)/t13?,14?,15?,17-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.10n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM50112127
PNG
(CHEMBL3608407 | US9464044, 76)
Show SMILES CC(C)(NS(=O)(=O)c1ccccc1F)C(=O)N[C@H]1C2CC3CC1CC(CO)(C3)C2
Show InChI InChI=1S/C21H29FN2O4S/c1-20(2,24-29(27,28)17-6-4-3-5-16(17)22)19(26)23-18-14-7-13-8-15(18)11-21(9-13,10-14)12-25/h3-6,13-15,18,24-25H,7-12H2,1-2H3,(H,23,26)/t13?,14?,15?,18-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.40n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250420
PNG
(US9464044, 10)
Show SMILES Cc1cccc(F)c1S(=O)(=O)NCC1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C23H30FN3O4S/c1-13-3-2-4-17(24)19(13)32(30,31)26-12-22(5-6-22)21(29)27-18-15-7-14-8-16(18)11-23(9-14,10-15)20(25)28/h2-4,14-16,18,26H,5-12H2,1H3,(H2,25,28)(H,27,29)/t14?,15?,16?,18-,23?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.5n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM50112126
PNG
(CHEMBL3608406 | US9464044, 74)
Show SMILES CC(C)(NS(=O)(=O)c1ccccc1F)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C#N
Show InChI InChI=1S/C21H26FN3O3S/c1-20(2,25-29(27,28)17-6-4-3-5-16(17)22)19(26)24-18-14-7-13-8-15(18)11-21(9-13,10-14)12-23/h3-6,13-15,18,25H,7-11H2,1-2H3,(H,24,26)/t13?,14?,15?,18-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.60n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250417
PNG
(US9464044, 7)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CNS(=O)(=O)c4cccc(Cl)c4)CC1)C(C3)C2
Show InChI InChI=1S/C22H28ClN3O4S/c23-16-2-1-3-17(8-16)31(29,30)25-12-21(4-5-21)20(28)26-18-14-6-13-7-15(18)11-22(9-13,10-14)19(24)27/h1-3,8,13-15,18,25H,4-7,9-12H2,(H2,24,27)(H,26,28)/t13?,14?,15?,18-,22?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.60n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250480
PNG
(US9464044, 113)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)c1cccc([N-]S(=O)(=O)c4cccc(Cl)c4F)c1)C(C3)C2
Show InChI InChI=1S/C24H24ClFN3O4S/c25-18-5-2-6-19(20(18)26)34(32,33)29-17-4-1-3-14(9-17)22(30)28-21-15-7-13-8-16(21)12-24(10-13,11-15)23(27)31/h1-6,9,13,15-16,21H,7-8,10-12H2,(H2,27,31)(H,28,30)/q-1/t13?,15?,16?,21-,24?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.70n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250416
PNG
(US9464044, 5)
Show SMILES Cc1c(Cl)cccc1S(=O)(=O)NCC1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C23H30ClN3O4S/c1-13-17(24)3-2-4-18(13)32(30,31)26-12-22(5-6-22)21(29)27-19-15-7-14-8-16(19)11-23(9-14,10-15)20(25)28/h2-4,14-16,19,26H,5-12H2,1H3,(H2,25,28)(H,27,29)/t14?,15?,16?,19-,23?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.70n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250423
PNG
(US9464044, 13)
Show SMILES CN(CC1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O)S(=O)(=O)c1c(C)cccc1F
Show InChI InChI=1S/C24H32FN3O4S/c1-14-4-3-5-18(25)20(14)33(31,32)28(2)13-23(6-7-23)22(30)27-19-16-8-15-9-17(19)12-24(10-15,11-16)21(26)29/h3-5,15-17,19H,6-13H2,1-2H3,(H2,26,29)(H,27,30)/t15?,16?,17?,19-,24?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.80n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250459
PNG
(US9464044, 61)
Show SMILES CN(C1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C22H28FN3O4S/c1-26(31(29,30)17-5-3-2-4-16(17)23)22(6-7-22)20(28)25-18-14-8-13-9-15(18)12-21(10-13,11-14)19(24)27/h2-5,13-15,18H,6-12H2,1H3,(H2,24,27)(H,25,28)/t13?,14?,15?,18-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.80n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250477
PNG
(US9464044, 106)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)c1cccc(NS(=O)(=O)c4ccccc4Cl)c1)C(C3)C2
Show InChI InChI=1S/C24H26ClN3O4S/c25-19-6-1-2-7-20(19)33(31,32)28-18-5-3-4-15(10-18)22(29)27-21-16-8-14-9-17(21)13-24(11-14,12-16)23(26)30/h1-7,10,14,16-17,21,28H,8-9,11-13H2,(H2,26,30)(H,27,29)/t14?,16?,17?,21-,24?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.80n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250484
PNG
(US9464044, 117)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)c1cccc(NS(=O)(=O)c4c(Cl)cc(Cl)cc4Cl)c1)C(C3)C2
Show InChI InChI=1S/C24H24Cl3N3O4S/c25-16-7-18(26)21(19(27)8-16)35(33,34)30-17-3-1-2-13(6-17)22(31)29-20-14-4-12-5-15(20)11-24(9-12,10-14)23(28)32/h1-3,6-8,12,14-15,20,30H,4-5,9-11H2,(H2,28,32)(H,29,31)/t12?,14?,15?,20-,24?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250426
PNG
(US9464044, 16)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CNS(=O)(=O)c4cc(Cl)c(Cl)cc4F)CC1)C(C3)C2
Show InChI InChI=1S/C22H26Cl2FN3O4S/c23-14-5-16(25)17(6-15(14)24)33(31,32)27-10-21(1-2-21)20(30)28-18-12-3-11-4-13(18)9-22(7-11,8-12)19(26)29/h5-6,11-13,18,27H,1-4,7-10H2,(H2,26,29)(H,28,30)/t11?,12?,13?,18-,22?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM50112141
PNG
(CHEMBL3609869 | US9464044, 3)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CNS(=O)(=O)c4ccccc4F)CC1)C(C3)C2
Show InChI InChI=1S/C22H28FN3O4S/c23-16-3-1-2-4-17(16)31(29,30)25-12-21(5-6-21)20(28)26-18-14-7-13-8-15(18)11-22(9-13,10-14)19(24)27/h1-4,13-15,18,25H,5-12H2,(H2,24,27)(H,26,28)/t13?,14?,15?,18-,22?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 6.20n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250465
PNG
(US9464044, 70)
Show SMILES Cc1c(Cl)cccc1S(=O)(=O)NCC(C)(C)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C23H32ClN3O4S/c1-13-17(24)5-4-6-18(13)32(30,31)26-12-22(2,3)21(29)27-19-15-7-14-8-16(19)11-23(9-14,10-15)20(25)28/h4-6,14-16,19,26H,7-12H2,1-3H3,(H2,25,28)(H,27,29)/t14?,15?,16?,19-,23?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.20n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250446
PNG
(US9464044, 42)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CC1)NS(=O)(=O)c1ccc(F)cc1)C(C3)C2
Show InChI InChI=1S/C21H26FN3O4S/c22-15-1-3-16(4-2-15)30(28,29)25-21(5-6-21)19(27)24-17-13-7-12-8-14(17)11-20(9-12,10-13)18(23)26/h1-4,12-14,17,25H,5-11H2,(H2,23,26)(H,24,27)/t12?,13?,14?,17-,20?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.40n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250443
PNG
(US9464044, 38)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CC1)NS(=O)(=O)c1cccc(Cl)c1)C(C3)C2
Show InChI InChI=1S/C21H26ClN3O4S/c22-15-2-1-3-16(8-15)30(28,29)25-21(4-5-21)19(27)24-17-13-6-12-7-14(17)11-20(9-12,10-13)18(23)26/h1-3,8,12-14,17,25H,4-7,9-11H2,(H2,23,26)(H,24,27)/t12?,13?,14?,17-,20?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.70n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250463
PNG
(US9464044, 67)
Show SMILES CC(C)(CNS(=O)(=O)c1cccc(Cl)c1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C22H30ClN3O4S/c1-21(2,12-25-31(29,30)17-5-3-4-16(23)8-17)20(28)26-18-14-6-13-7-15(18)11-22(9-13,10-14)19(24)27/h3-5,8,13-15,18,25H,6-7,9-12H2,1-2H3,(H2,24,27)(H,26,28)/t13?,14?,15?,18-,22?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.10n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250488
PNG
(US9464044, 121)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)c1cccc(NS(=O)(=O)c4ccc(F)cc4F)c1)C(C3)C2
Show InChI InChI=1S/C24H25F2N3O4S/c25-17-4-5-20(19(26)9-17)34(32,33)29-18-3-1-2-14(8-18)22(30)28-21-15-6-13-7-16(21)12-24(10-13,11-15)23(27)31/h1-5,8-9,13,15-16,21,29H,6-7,10-12H2,(H2,27,31)(H,28,30)/t13?,15?,16?,21-,24?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.80n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250454
PNG
(US9464044, 55)
Show SMILES Clc1cccc(c1)S(=O)(=O)NC1(CC1)C(=O)NC1CC2CCC1C2
Show InChI InChI=1S/C17H21ClN2O3S/c18-13-2-1-3-14(10-13)24(22,23)20-17(6-7-17)16(21)19-15-9-11-4-5-12(15)8-11/h1-3,10-12,15,20H,4-9H2,(H,19,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.30n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM50112140
PNG
(CHEMBL3609868 | US9464044, 68)
Show SMILES CC(C)(CNS(=O)(=O)c1ccccc1F)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C22H30FN3O4S/c1-21(2,12-25-31(29,30)17-6-4-3-5-16(17)23)20(28)26-18-14-7-13-8-15(18)11-22(9-13,10-14)19(24)27/h3-6,13-15,18,25H,7-12H2,1-2H3,(H2,24,27)(H,26,28)/t13?,14?,15?,18-,22?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 8.90n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250455
PNG
(US9464044, 57)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CC1)NC(=O)c1ccc(F)c(F)c1)C(C3)C2
Show InChI InChI=1S/C22H25F2N3O3/c23-15-2-1-12(7-16(15)24)18(28)27-22(3-4-22)20(30)26-17-13-5-11-6-14(17)10-21(8-11,9-13)19(25)29/h1-2,7,11,13-14,17H,3-6,8-10H2,(H2,25,29)(H,26,30)(H,27,28)/t11?,13?,14?,17-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.30n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250422
PNG
(US9464044, 12)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CNS(=O)(=O)c4c(F)cc(F)cc4F)CC1)C(C3)C2
Show InChI InChI=1S/C22H26F3N3O4S/c23-14-5-15(24)18(16(25)6-14)33(31,32)27-10-21(1-2-21)20(30)28-17-12-3-11-4-13(17)9-22(7-11,8-12)19(26)29/h5-6,11-13,17,27H,1-4,7-10H2,(H2,26,29)(H,28,30)/t11?,12?,13?,17-,22?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.5n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250434
PNG
(US9464044, 25)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CNC(=O)c4ccc(F)c(F)c4)CC1)C(C3)C2
Show InChI InChI=1S/C23H27F2N3O3/c24-16-2-1-13(7-17(16)25)19(29)27-11-22(3-4-22)21(31)28-18-14-5-12-6-15(18)10-23(8-12,9-14)20(26)30/h1-2,7,12,14-15,18H,3-6,8-11H2,(H2,26,30)(H,27,29)(H,28,31)/t12?,14?,15?,18-,23?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.60n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM50112153
PNG
(CHEMBL3608402 | US9464044, 83)
Show SMILES CC(C)(NS(=O)(=O)c1cc(F)cc(F)c1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C21H27F2N3O4S/c1-20(2,26-31(29,30)16-6-14(22)5-15(23)7-16)19(28)25-17-12-3-11-4-13(17)10-21(8-11,9-12)18(24)27/h5-7,11-13,17,26H,3-4,8-10H2,1-2H3,(H2,24,27)(H,25,28)/t11?,12?,13?,17-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 9.90n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250445
PNG
(US9464044, 41)
Show SMILES Cc1c(Cl)cccc1S(=O)(=O)NC1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C22H28ClN3O4S/c1-12-16(23)3-2-4-17(12)31(29,30)26-22(5-6-22)20(28)25-18-14-7-13-8-15(18)11-21(9-13,10-14)19(24)27/h2-4,13-15,18,26H,5-11H2,1H3,(H2,24,27)(H,25,28)/t13?,14?,15?,18-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 10n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250421
PNG
(US9464044, 11 | US9464044, 24)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CNS(=O)(=O)c4cccc(F)c4F)CC1)C(C3)C2
Show InChI InChI=1S/C22H27F2N3O4S/c23-15-2-1-3-16(17(15)24)32(30,31)26-11-21(4-5-21)20(29)27-18-13-6-12-7-14(18)10-22(8-12,9-13)19(25)28/h1-3,12-14,18,26H,4-11H2,(H2,25,28)(H,27,29)/t12?,13?,14?,18-,22?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 10.4n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250457
PNG
(US9464044, 59)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CC1)NC(=O)c1cccc(F)c1F)C(C3)C2
Show InChI InChI=1S/C22H25F2N3O3/c23-15-3-1-2-14(16(15)24)18(28)27-22(4-5-22)20(30)26-17-12-6-11-7-13(17)10-21(8-11,9-12)19(25)29/h1-3,11-13,17H,4-10H2,(H2,25,29)(H,26,30)(H,27,28)/t11?,12?,13?,17-,21?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 11.2n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250491
PNG
(US9464044, 125)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)c1cccc(NS(=O)(=O)c4ccccc4C(F)(F)F)c1F)C(C3)C2
Show InChI InChI=1S/C25H25F4N3O4S/c26-20-16(22(33)31-21-14-8-13-9-15(21)12-24(10-13,11-14)23(30)34)4-3-6-18(20)32-37(35,36)19-7-2-1-5-17(19)25(27,28)29/h1-7,13-15,21,32H,8-12H2,(H2,30,34)(H,31,33)/t13?,14?,15?,21-,24?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 11.6n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250458
PNG
(US9464044, 60)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)C1(CC1)NS(=O)(=O)c1ccccc1)C(C3)C2
Show InChI InChI=1S/C21H27N3O4S/c22-18(25)20-10-13-8-14(11-20)17(15(9-13)12-20)23-19(26)21(6-7-21)24-29(27,28)16-4-2-1-3-5-16/h1-5,13-15,17,24H,6-12H2,(H2,22,25)(H,23,26)/t13?,14?,15?,17-,20?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12.6n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250490
PNG
(US9464044, 123)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)c1cccc(NS(=O)(=O)c4c(F)cccc4F)c1)C(C3)C2
Show InChI InChI=1S/C24H25F2N3O4S/c25-18-5-2-6-19(26)21(18)34(32,33)29-17-4-1-3-14(9-17)22(30)28-20-15-7-13-8-16(20)12-24(10-13,11-15)23(27)31/h1-6,9,13,15-16,20,29H,7-8,10-12H2,(H2,27,31)(H,28,30)/t13?,15?,16?,20-,24?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12.8n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250470
PNG
(US9464044, 95)
Show SMILES NC(=O)C12CC3CC(C1)[C@H](NC(=O)c1cccc(NS(=O)(=O)c4cccc(Cl)c4)c1)C(C3)C2
Show InChI InChI=1S/C24H26ClN3O4S/c25-18-4-2-6-20(10-18)33(31,32)28-19-5-1-3-15(9-19)22(29)27-21-16-7-14-8-17(21)13-24(11-14,12-16)23(26)30/h1-6,9-10,14,16-17,21,28H,7-8,11-13H2,(H2,26,30)(H,27,29)/t14?,16?,17?,21-,24?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 13.1n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250424
PNG
(US9464044, 14)
Show SMILES Cc1cc(c(Cl)cc1Cl)S(=O)(=O)NCC1(CC1)C(=O)N[C@H]1C2CC3CC1CC(C3)(C2)C(N)=O
Show InChI InChI=1S/C23H29Cl2N3O4S/c1-12-4-18(17(25)7-16(12)24)33(31,32)27-11-22(2-3-22)21(30)28-19-14-5-13-6-15(19)10-23(8-13,9-14)20(26)29/h4,7,13-15,19,27H,2-3,5-6,8-11H2,1H3,(H2,26,29)(H,28,30)/t13?,14?,15?,19-,23?
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 13.3n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (human))
BDBM250414
PNG
(US9464044, 1)
Show SMILES Cc1c(Cl)cccc1S(=O)(=O)NCC1(CC1)C(=O)N[C@H]1C2CC3CC(C2)CC1C3
Show InChI InChI=1S/C22H29ClN2O3S/c1-13-18(23)3-2-4-19(13)29(27,28)24-12-22(5-6-22)21(26)25-20-16-8-14-7-15(10-16)11-17(20)9-14/h2-4,14-17,20,24H,5-12H2,1H3,(H,25,26)/t14?,15?,16?,17?,20-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 14.2n/an/an/an/an/an/a



AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

US Patent


Assay Description
The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...


US Patent US9464044 (2016)


BindingDB Entry DOI: 10.7270/Q2SJ1JH0
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 101 total )  |  Next  |  Last  >>
Jump to: