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Compile Data Set for Download or QSAR

Found 188 hits from ALLERGAN, INC.   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350507
PNG
((2S)-2-({[(3,4- dichlorophenyl)amino]carbonyl}amin...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1/C16H14Cl2N2O3/c17-12-7-6-11(9-13(12)18)19-16(23)20-14(15(21)22)8-10-4-2-1-3-5-10/h1-7,9,14H,8H2,(H,21,22)(H2,19,20,23)
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n/an/an/an/a 1.00E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350508
PNG
((2S)-2-({[(4- nitrophenyl)amino]carbonyl}amino)- 3...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)Nc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1/C16H15N3O5/c20-15(21)14(10-11-4-2-1-3-5-11)18-16(22)17-12-6-8-13(9-7-12)19(23)24/h1-9,14H,10H2,(H,20,21)(H2,17,18,22)
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n/an/an/an/a 574n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350509
PNG
(3-phenyl-2-[({[4- (trifluoromethoxy)phenyl]amino} ...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)Nc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1/C17H15F3N2O4/c18-17(19,20)26-13-8-6-12(7-9-13)21-16(25)22-14(15(23)24)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,23,24)(H2,21,22,25)
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n/an/an/an/a 1.57E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350510
PNG
(2-({[(3,4- dimethoxyphenyl)amino]carbonyl} amino)-...)
Show SMILES COc1ccc(NC(=O)NC(Cc2ccccc2)C(O)=O)cc1OC
Show InChI InChI=1/C18H20N2O5/c1-24-15-9-8-13(11-16(15)25-2)19-18(23)20-14(17(21)22)10-12-6-4-3-5-7-12/h3-9,11,14H,10H2,1-2H3,(H,21,22)(H2,19,20,23)
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n/an/an/an/a 2.79E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM414430
PNG
(US10434112, Table 1.8 | methyl 2-({[(4- iodophenyl...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)Nc1ccc(I)cc1
Show InChI InChI=1S/C16H15IN2O3/c17-12-6-8-13(9-7-12)18-16(22)19-14(15(20)21)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,20,21)(H2,18,19,22)/t14-/m1/s1
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n/an/an/an/a 14.3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350513
PNG
((2R)-2-({[(4- bromophenyl)amino]carbonyl}amino)- 3...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1/C16H15BrN2O3/c17-12-6-8-13(9-7-12)18-16(22)19-14(15(20)21)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,20,21)(H2,18,19,22)/t14-/s2
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n/an/an/an/a 31n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350513
PNG
((2R)-2-({[(4- bromophenyl)amino]carbonyl}amino)- 3...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1/C16H15BrN2O3/c17-12-6-8-13(9-7-12)18-16(22)19-14(15(20)21)10-11-4-2-1-3-5-11/h1-9,14H,10H2,(H,20,21)(H2,18,19,22)/t14-/s2
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n/an/an/an/a 1.82E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350515
PNG
((2S,3S)-2-({[(4- bromophenyl)amino]carbonyl}amino)...)
Show SMILES CC[C@H](C)[C@H](NC(=O)Nc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1/C13H17BrN2O3/c1-3-8(2)11(12(17)18)16-13(19)15-10-6-4-9(14)5-7-10/h4-8,11H,3H2,1-2H3,(H,17,18)(H2,15,16,19)/t8-,11-/s2
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n/an/an/an/a 4.10n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350516
PNG
((2S)-({[(4- bromophenyl)amino]carbonyl}amino) (phe...)
Show SMILES OC(=O)[C@@H](NC(=O)Nc1ccc(Br)cc1)c1ccccc1
Show InChI InChI=1/C15H13BrN2O3/c16-11-6-8-12(9-7-11)17-15(21)18-13(14(19)20)10-4-2-1-3-5-10/h1-9,13H,(H,19,20)(H2,17,18,21)/t13-/s2
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n/an/an/an/a 25.8n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350517
PNG
(2-({[(4- bromophenyl)amino]carbonyl}amino)- 3-(1H-...)
Show SMILES OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1/C18H16BrN3O3/c19-12-5-7-13(8-6-12)21-18(25)22-16(17(23)24)9-11-10-20-15-4-2-1-3-14(11)15/h1-8,10,16,20H,9H2,(H,23,24)(H2,21,22,25)
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n/an/an/an/a 67n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350518
PNG
((2S)-2-({[(4- bromophenyl)amino]carbonyl}amino)- 3...)
Show SMILES CC(C)[C@H](NC(=O)Nc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1/C12H15BrN2O3/c1-7(2)10(11(16)17)15-12(18)14-9-5-3-8(13)4-6-9/h3-7,10H,1-2H3,(H,16,17)(H2,14,15,18)/t10-/s2
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n/an/an/an/a 72n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350519
PNG
((2S)-2-({[(4-bromo-2- fluorophenyl)amino]carbonyl}...)
Show SMILES CC(C)[C@H](NC(=O)Nc1ccc(Br)cc1F)C(O)=O
Show InChI InChI=1/C12H14BrFN2O3/c1-6(2)10(11(17)18)16-12(19)15-9-4-3-7(13)5-8(9)14/h3-6,10H,1-2H3,(H,17,18)(H2,15,16,19)/t10-/s2
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n/an/an/an/a 152n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350520
PNG
(1-(4-chlorophenyl)-3-(2,4-dioxo- 1,3-diazaspiro[4,...)
Show SMILES Clc1ccc(NC(=O)NN2C(=O)NC3(CCCCC3)C2=O)cc1
Show InChI InChI=1S/C15H17ClN4O3/c16-10-4-6-11(7-5-10)17-13(22)19-20-12(21)15(18-14(20)23)8-2-1-3-9-15/h4-7H,1-3,8-9H2,(H,18,23)(H2,17,19,22)
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n/an/an/an/a 49n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350521
PNG
(1-(4-chlorophenyl)-3-(4-ethyl-4- methyl-2,5-dioxoi...)
Show SMILES CCC1(C)NC(=O)N(NC(=O)Nc2ccc(Cl)cc2)C1=O
Show InChI InChI=1/C13H15ClN4O3/c1-3-13(2)10(19)18(12(21)16-13)17-11(20)15-9-6-4-8(14)5-7-9/h4-7H,3H2,1-2H3,(H,16,21)(H2,15,17,20)
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n/an/an/an/a 157n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350522
PNG
(1-[4-methyl-2,5-dioxo-4-(2- phenylethyl)imidazolid...)
Show SMILES CC1(CCc2ccccc2)NC(=O)N(NC(=O)Nc2ccccc2)C1=O
Show InChI InChI=1/C19H20N4O3/c1-19(13-12-14-8-4-2-5-9-14)16(24)23(18(26)21-19)22-17(25)20-15-10-6-3-7-11-15/h2-11H,12-13H2,1H3,(H,21,26)(H2,20,22,25)
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n/an/an/an/a 223n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350523
PNG
(1-(8-methyl-2,4-dioxo-1,3- diazaspiro[4,5]decan-3-...)
Show SMILES CC1CCC2(CC1)NC(=O)N(NC(=O)Nc1ccc(C)cc1)C2=O
Show InChI InChI=1S/C17H22N4O3/c1-11-3-5-13(6-4-11)18-15(23)20-21-14(22)17(19-16(21)24)9-7-12(2)8-10-17/h3-6,12H,7-10H2,1-2H3,(H,19,24)(H2,18,20,23)
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n/an/an/an/a 363n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350524
PNG
(1-(2-fluorophenyl)-3-[4-methyl- 2,5-dioxo-4-(2- ph...)
Show SMILES CC1(CCc2ccccc2)NC(=O)N(NC(=O)Nc2ccccc2F)C1=O
Show InChI InChI=1/C19H19FN4O3/c1-19(12-11-13-7-3-2-4-8-13)16(25)24(18(27)22-19)23-17(26)21-15-10-6-5-9-14(15)20/h2-10H,11-12H2,1H3,(H,22,27)(H2,21,23,26)
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n/an/an/an/a 258n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350525
PNG
(N-(4-bromophenyl)-2-(4,4-dimethyl- 2,5-dioxoimidaz...)
Show SMILES CC1(C)NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C13H14BrN3O3/c1-13(2)11(19)17(12(20)16-13)7-10(18)15-9-5-3-8(14)4-6-9/h3-6H,7H2,1-2H3,(H,15,18)(H,16,20)
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n/an/an/an/a 719n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350526
PNG
(N-(4-bromophenyl)-2-(4,4-diethyl- 2,5-dioxoimidazo...)
Show SMILES CCC1(CC)NC(=O)N(CC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C15H18BrN3O3/c1-3-15(4-2)13(21)19(14(22)18-15)9-12(20)17-11-7-5-10(16)6-8-11/h5-8H,3-4,9H2,1-2H3,(H,17,20)(H,18,22)
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n/an/an/an/a 96n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350527
PNG
(N-(4-bromophenyl)-2-(2,4-dioxo-1,3- diazaspiro[4.5...)
Show SMILES Brc1ccc(NC(=O)CN2C(=O)NC3(CCCCC3)C2=O)cc1
Show InChI InChI=1S/C16H18BrN3O3/c17-11-4-6-12(7-5-11)18-13(21)10-20-14(22)16(19-15(20)23)8-2-1-3-9-16/h4-7H,1-3,8-10H2,(H,18,21)(H,19,23)
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n/an/an/an/a 738n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM414448
PNG
(N-(4-bromophenyl)-2-(2,4-dioxo-1,3- diazaspiro[4.4...)
Show SMILES Brc1ccc(NC(=O)NN2C(=O)NC3(CCCC3)C2=O)cc1
Show InChI InChI=1S/C14H15BrN4O3/c15-9-3-5-10(6-4-9)16-12(21)18-19-11(20)14(17-13(19)22)7-1-2-8-14/h3-6H,1-2,7-8H2,(H,17,22)(H2,16,18,21)
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n/an/an/an/a 322n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM414449
PNG
(N-(4-bromophenyl)-2-(2,5-dioxo-4,4- dipropylimidaz...)
Show SMILES CCCC1(CCC)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C16H21BrN4O3/c1-3-9-16(10-4-2)13(22)21(15(24)19-16)20-14(23)18-12-7-5-11(17)6-8-12/h5-8H,3-4,9-10H2,1-2H3,(H,19,24)(H2,18,20,23)
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n/an/an/an/a 645n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM414450
PNG
(N-(4-bromophenyl)-2-(4-ethyl-2,5- dioxo-4-phenylim...)
Show SMILES CCC1(NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O)c1ccccc1
Show InChI InChI=1S/C18H17BrN4O3/c1-2-18(12-6-4-3-5-7-12)15(24)23(17(26)21-18)22-16(25)20-14-10-8-13(19)9-11-14/h3-11H,2H2,1H3,(H,21,26)(H2,20,22,25)
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n/an/an/an/a 523n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM414451
PNG
(N-(4-bromophenyl)-2-(4-cyclopropyl- 4-methyl-2,5-d...)
Show SMILES CC1(NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O)C1CC1
Show InChI InChI=1S/C14H15BrN4O3/c1-14(8-2-3-8)11(20)19(13(22)17-14)18-12(21)16-10-6-4-9(15)5-7-10/h4-8H,2-3H2,1H3,(H,17,22)(H2,16,18,21)
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n/an/an/an/a 166n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM414452
PNG
(N-(4-bromophenyl)-2-(2,4-dioxo-1,3- diazaspiro[4.6...)
Show SMILES Brc1ccc(NC(=O)NN2C(=O)NC3(CCCCCC3)C2=O)cc1
Show InChI InChI=1S/C16H19BrN4O3/c17-11-5-7-12(8-6-11)18-14(23)20-21-13(22)16(19-15(21)24)9-3-1-2-4-10-16/h5-8H,1-4,9-10H2,(H,19,24)(H2,18,20,23)
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n/an/an/an/a 679n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM414453
PNG
(N-(4-bromophenyl)-2-(4-ethyl-4- methyl-2,5-dioxoim...)
Show SMILES CCC1(C)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1S/C13H15BrN4O3/c1-3-13(2)10(19)18(12(21)16-13)17-11(20)15-9-6-4-8(14)5-7-9/h4-7H,3H2,1-2H3,(H,16,21)(H2,15,17,20)
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n/an/an/an/a 485n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM414454
PNG
(N-(4-chlorophenyl)-2-(4,4-diethyl- 2,5-dioxoimidaz...)
Show SMILES CCC1(CC)NC(=O)N(NC(=O)Nc2ccc(Cl)cc2)C1=O
Show InChI InChI=1S/C14H17ClN4O3/c1-3-14(4-2)11(20)19(13(22)17-14)18-12(21)16-10-7-5-9(15)6-8-10/h5-8H,3-4H2,1-2H3,(H,17,22)(H2,16,18,21)
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n/an/an/an/a 314n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM414455
PNG
(2-(4,4-diethyl-2,5-dioxoimidazolidin- 1-yl)-N-(4-f...)
Show SMILES CCC1(CC)NC(=O)N(NC(=O)Nc2ccc(F)cc2)C1=O
Show InChI InChI=1S/C14H17FN4O3/c1-3-14(4-2)11(20)19(13(22)17-14)18-12(21)16-10-7-5-9(15)6-8-10/h5-8H,3-4H2,1-2H3,(H,17,22)(H2,16,18,21)
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n/an/an/an/a 2.77E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350592
PNG
(1-(4-bromophenyl)-3-[4- methyl-2,5-dioxo-4-(2- phe...)
Show SMILES CC1(CCc2ccccc2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1/C19H19BrN4O3/c1-19(12-11-13-5-3-2-4-6-13)16(25)24(18(27)22-19)23-17(26)21-15-9-7-14(20)8-10-15/h2-10H,11-12H2,1H3,(H,22,27)(H2,21,23,26)
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n/an/an/an/a 860n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350537
PNG
(N-(4-bromophenyl)-1,3,3a,4,7,7a- hexahydro-1,3-dio...)
Show SMILES Brc1ccc(NC(=O)CN2C(=O)C3C4CC(C=C4)C3C2=O)cc1
Show InChI InChI=1/C17H15BrN2O3/c18-11-3-5-12(6-4-11)19-13(21)8-20-16(22)14-9-1-2-10(7-9)15(14)17(20)23/h1-6,9-10,14-15H,7-8H2,(H,19,21)
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n/an/an/an/a 5.75E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350538
PNG
(N-(4-bromophenyl)-1,3,3a,4,7,7a- hexahydro-1,3-dio...)
Show SMILES Brc1ccc(NC(=O)CN2C(=O)C3CC=CCC3C2=O)cc1
Show InChI InChI=1/C16H15BrN2O3/c17-10-5-7-11(8-6-10)18-14(20)9-19-15(21)12-3-1-2-4-13(12)16(19)22/h1-2,5-8,12-13H,3-4,9H2,(H,18,20)
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n/an/an/an/a 3.95E+5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350539
PNG
(1-(4-bromophenyl)-3-[4-ethyl- 2,5-dioxo-4-(2- phen...)
Show SMILES CCC1(CCc2ccccc2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Show InChI InChI=1/C20H21BrN4O3/c1-2-20(13-12-14-6-4-3-5-7-14)17(26)25(19(28)23-20)24-18(27)22-16-10-8-15(21)9-11-16/h3-11H,2,12-13H2,1H3,(H,23,28)(H2,22,24,27)
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n/an/an/an/a 3.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350540
PNG
(US10208071, Compound 2 | US10434112, Compound 2 | ...)
Show SMILES CCC[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(O)=O
Show InChI InChI=1/C14H18BrN3O4/c1-2-3-11(13(21)16-8-12(19)20)18-14(22)17-10-6-4-9(15)5-7-10/h4-7,11H,2-3,8H2,1H3,(H,16,21)(H,19,20)(H2,17,18,22)/t11-/s2
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n/an/an/an/a 2.00E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350541
PNG
(US10208071, Compound 3 | US10434112, Compound 3 | ...)
Show SMILES CC[C@H](C)[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(O)=O
Show InChI InChI=1/C15H20BrN3O4/c1-3-9(2)13(14(22)17-8-12(20)21)19-15(23)18-11-6-4-10(16)5-7-11/h4-7,9,13H,3,8H2,1-2H3,(H,17,22)(H,20,21)(H2,18,19,23)/t9-,13-/s2
PDB

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n/an/an/an/a 1.98E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350542
PNG
(1-(4-bromophenyl)-3-[4-ethyl- 2,5-dioxo-4-(propan-...)
Show SMILES CCC1(NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O)C(C)C
Show InChI InChI=1/C15H19BrN4O3/c1-4-15(9(2)3)12(21)20(14(23)18-15)19-13(22)17-11-7-5-10(16)6-8-11/h5-9H,4H2,1-3H3,(H,18,23)(H2,17,19,22)
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n/an/an/an/a 6.70E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350543
PNG
((2S,3S)-2-{[(4-bromo-2- fluorophenyl)carbamoyl]ami...)
Show SMILES CC[C@H](C)[C@H](NC(=O)Nc1ccc(Br)cc1F)C(O)=O
Show InChI InChI=1/C13H16BrFN2O3/c1-3-7(2)11(12(18)19)17-13(20)16-10-5-4-8(14)6-9(10)15/h4-7,11H,3H2,1-2H3,(H,18,19)(H2,16,17,20)/t7-,11-/s2
PDB

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n/an/an/an/a 3.10E+4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350544
PNG
(2-{[(2S)-2-{[(4- bromophenyl)carbamoyl] amino}-4- ...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NC(C)(C)C(O)=O
Show InChI InChI=1/C17H24BrN3O4/c1-10(2)9-13(14(22)21-17(3,4)15(23)24)20-16(25)19-12-7-5-11(18)6-8-12/h5-8,10,13H,9H2,1-4H3,(H,21,22)(H,23,24)(H2,19,20,25)/t13-/s2
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n/an/an/an/a 1.66E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350545
PNG
(US10208071, Compound 7 | US10434112, Compound 7 | ...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1F)C(=O)NCC(O)=O
Show InChI InChI=1/C15H19BrFN3O4/c1-8(2)5-12(14(23)18-7-13(21)22)20-15(24)19-11-4-3-9(16)6-10(11)17/h3-4,6,8,12H,5,7H2,1-2H3,(H,18,23)(H,21,22)(H2,19,20,24)/t12-/s2
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n/an/an/an/a 3.57E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350546
PNG
(US10208071, Compound 8 | US10434112, Compound 90 |...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(=O)NCC(O)=O
Show InChI InChI=1/C15H20BrN3O4/c1-9(2)7-12(14(22)17-8-13(20)21)19-15(23)18-11-5-3-10(16)4-6-11/h3-6,9,12H,7-8H2,1-2H3,(H,17,22)(H,20,21)(H2,18,19,23)/t12-/s2
PDB

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n/an/an/an/a 780n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350547
PNG
((2S)-2-{[(4- bromophenyl)carbamoyl]amino}-4- methy...)
Show SMILES CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1/C13H17BrN2O3/c1-8(2)7-11(12(17)18)16-13(19)15-10-5-3-9(14)4-6-10/h3-6,8,11H,7H2,1-2H3,(H,17,18)(H2,15,16,19)/t11-/s2
PDB

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n/an/an/an/a 5.95E+3n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350548
PNG
(2-{[(4- bromophenyl)carbamoyl]amino}-N- (2-oxoazep...)
Show SMILES Brc1ccc(NC(=O)NC(Cc2ccccc2)C(=O)NC2CCCCNC2=O)cc1
Show InChI InChI=1/C22H25BrN4O3/c23-16-9-11-17(12-10-16)25-22(30)27-19(14-15-6-2-1-3-7-15)21(29)26-18-8-4-5-13-24-20(18)28/h1-3,6-7,9-12,18-19H,4-5,8,13-14H2,(H,24,28)(H,26,29)(H2,25,27,30)
PDB

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n/an/an/an/a 11n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350549
PNG
(3-[(4- iodophenyl)carbamoyl] spiro[bicyclo[2.2.1]h...)
Show SMILES OC(=O)C1C2C=CC(C1C(=O)Nc1ccc(I)cc1)C21CC1
Show InChI InChI=1/C17H16INO3/c18-9-1-3-10(4-2-9)19-15(20)13-11-5-6-12(14(13)16(21)22)17(11)7-8-17/h1-6,11-14H,7-8H2,(H,19,20)(H,21,22)
PDB

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n/an/an/an/a 1.60n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350550
PNG
(3-[(4- bromophenyl)carbamoyl] spiro[bicyclo[2.2.1]...)
Show SMILES OC(=O)C1C2C=CC(C1C(=O)Nc1ccc(Br)cc1)C21CC1
Show InChI InChI=1/C17H16BrNO3/c18-9-1-3-10(4-2-9)19-15(20)13-11-5-6-12(14(13)16(21)22)17(11)7-8-17/h1-6,11-14H,7-8H2,(H,19,20)(H,21,22)
PDB

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n/an/an/an/a 4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350551
PNG
(1-(4-acetylphenyl)-3-{3-(4- cyanophenyl)-2-[2-(1H-...)
Show SMILES CC(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1/C30H26N6O3/c1-19(37)21-6-9-24(10-7-21)34-30(39)35-25-11-8-23-14-28(22-4-2-20(16-31)3-5-22)36(29(38)27(23)15-25)13-12-26-17-32-18-33-26/h2-11,15,17-18,28H,12-14H2,1H3,(H,32,33)(H2,34,35,39)
PDB

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n/an/an/an/a 11n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM414473
PNG
(US10434112, Compound 14 | rel-(2R,3S)-3-[(4- bromo...)
Show SMILES OC(=O)C1C2CCC(C1C(=O)N[C]=1=C=CC(Br)=CC=1)C21CC1
Show InChI InChI=1S/C17H17BrNO3/c18-9-1-3-10(4-2-9)19-15(20)13-11-5-6-12(14(13)16(21)22)17(11)7-8-17/h1-3,11-14H,5-8H2,(H,19,20)(H,21,22)
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n/an/an/an/a 4n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350553
PNG
(3-[(4- iodophenyl)carbamoyl] spiro[bicyclo[2.2.1]h...)
Show SMILES OC(=O)C1C2CCC(C1C(=O)Nc1ccc(I)cc1)C21CC1
Show InChI InChI=1/C17H18INO3/c18-9-1-3-10(4-2-9)19-15(20)13-11-5-6-12(14(13)16(21)22)17(11)7-8-17/h1-4,11-14H,5-8H2,(H,19,20)(H,21,22)
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n/an/an/an/a 0.600n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350554
PNG
(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Show SMILES CSc1ccc(NC(=O)Nc2ccc3CC(N(CCCN)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1/C27H27N5O2S/c1-35-23-11-9-21(10-12-23)30-27(34)31-22-8-7-20-15-25(19-5-3-18(17-29)4-6-19)32(14-2-13-28)26(33)24(20)16-22/h3-12,16,25H,2,13-15,28H2,1H3,(H2,30,31,34)
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n/an/an/an/a 2.5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350555
PNG
(1-{3-(4-cyanophenyl)-2-[2- (1H-imidazol-4-yl)ethyl...)
Show SMILES CSc1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1/C29H26N6O2S/c1-38-25-10-8-22(9-11-25)33-29(37)34-23-7-6-21-14-27(20-4-2-19(16-30)3-5-20)35(28(36)26(21)15-23)13-12-24-17-31-18-32-24/h2-11,15,17-18,27H,12-14H2,1H3,(H,31,32)(H2,33,34,37)
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n/an/an/an/a 5.5n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350556
PNG
(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Show SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCCN)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1/C27H27N5O4S/c1-37(35,36)23-11-9-21(10-12-23)30-27(34)31-22-8-7-20-15-25(19-5-3-18(17-29)4-6-19)32(14-2-13-28)26(33)24(20)16-22/h3-12,16,25H,2,13-15,28H2,1H3,(H2,30,31,34)
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n/an/an/an/a 10n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM350557
PNG
(1-{3-(4-cyanophenyl)-2-[2- (1H-imidazol-4-yl)ethyl...)
Show SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(cc2)C#N)cc1
Show InChI InChI=1/C29H26N6O4S/c1-40(38,39)25-10-8-22(9-11-25)33-29(37)34-23-7-6-21-14-27(20-4-2-19(16-30)3-5-20)35(28(36)26(21)15-23)13-12-24-17-31-18-32-24/h2-11,15,17-18,27H,12-14H2,1H3,(H,31,32)(H2,33,34,37)
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n/an/an/an/a 20n/an/an/an/a



ALLERGAN, INC.

US Patent


Assay Description
HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...


US Patent US10434112 (2019)

More data for this
Ligand-Target Pair
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