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Compile Data Set for Download or QSAR

Found 14 hits from AMITECH THERAPEUTIC SOLUTIONS, INC.   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a 52n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Kit (Kit)


(Homo sapiens (Human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a 170n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor


(Homo sapiens (Human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a 300n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a 520n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
CDKL2


(Homo sapiens (Human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a 5.10E+3n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
PITSLRE serine/threonine-protein kinase CDC2L1


(Homo sapiens (Human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a 7.50E+3n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a>1.00E+4n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
RAF serine/threonine protein kinase


(Homo sapiens (human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a>1.00E+4n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
Macrophage colony stimulating factor receptor


(Homo sapiens (human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a>1.00E+4n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a>1.00E+4n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a>1.00E+4n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
PAK1


(Homo sapiens (Human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a>1.00E+4n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Re


(Homo sapiens (Human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a>1.00E+4n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))
BDBM205483
PNG
(US9260417, 6)
Show SMILES CSc1nc(N)cc(Oc2ccc(cc2)-c2nnc(Nc3cccc(c3)C(F)(F)F)[nH]2)n1
Show InChI InChI=1S/C20H16F3N7OS/c1-32-19-26-15(24)10-16(27-19)31-14-7-5-11(6-8-14)17-28-18(30-29-17)25-13-4-2-3-12(9-13)20(21,22)23/h2-10H,1H3,(H2,24,26,27)(H2,25,28,29,30)
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n/an/an/a>1.00E+4n/an/an/an/an/a



AMITECH THERAPEUTIC SOLUTIONS, INC.

US Patent


Assay Description
For the competitive binding assay, test compounds were screened at 10 uM against 70 diverse kinase targets for competitive binding using the KINOMEsc...


US Patent US9260417 (2016)


BindingDB Entry DOI: 10.7270/Q270807Z
More data for this
Ligand-Target Pair