BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 701 hits from Acetylon Pharmaceuticals, Inc.   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase


(Homo sapiens (human))
BDBM139285
PNG
(US8614223, 62 | US8614223, 66)
Show SMILES C[C@@H](Nc1ncc(cn1)C(=O)NO)c1ccccc1
Show InChI InChI=1S/C13H14N4O2/c1-9(10-5-3-2-4-6-10)16-13-14-7-11(8-15-13)12(18)17-19/h2-9,19H,1H3,(H,17,18)(H,14,15,16)/t9-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139312
PNG
(US8614223, 90)
Show SMILES ONC(=O)c1cnc(NC2(CC2)c2ccccc2Cl)nc1
Show InChI InChI=1S/C14H13ClN4O2/c15-11-4-2-1-3-10(11)14(5-6-14)18-13-16-7-9(8-17-13)12(20)19-21/h1-4,7-8,21H,5-6H2,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139258
PNG
(US8614223, 34)
Show SMILES ONC(=O)c1cnc(NCc2cccc(Cl)c2)nc1
Show InChI InChI=1S/C12H11ClN4O2/c13-10-3-1-2-8(4-10)5-14-12-15-6-9(7-16-12)11(18)17-19/h1-4,6-7,19H,5H2,(H,17,18)(H,14,15,16)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139338
PNG
(US8614223, 124)
Show SMILES ONC(=O)c1cnc(NC2(CC2)c2c(F)cccc2F)nc1
Show InChI InChI=1S/C14H12F2N4O2/c15-9-2-1-3-10(16)11(9)14(4-5-14)19-13-17-6-8(7-18-13)12(21)20-22/h1-3,6-7,22H,4-5H2,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213161
PNG
(US9278963, 008)
Show SMILES COc1ccc(NC(=O)N2CCC(CC2)(Nc2ncc(cn2)C(=O)NO)c2ccccc2)cc1
Show InChI InChI=1S/C24H26N6O4/c1-34-20-9-7-19(8-10-20)27-23(32)30-13-11-24(12-14-30,18-5-3-2-4-6-18)28-22-25-15-17(16-26-22)21(31)29-33/h2-10,15-16,33H,11-14H2,1H3,(H,27,32)(H,29,31)(H,25,26,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.5n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213156
PNG
(US9278963, 003)
Show SMILES CC(=O)N1CCC(CC1)(Nc1ncc(cn1)C(=O)NO)c1ccccc1
Show InChI InChI=1S/C18H21N5O3/c1-13(24)23-9-7-18(8-10-23,15-5-3-2-4-6-15)21-17-19-11-14(12-20-17)16(25)22-26/h2-6,11-12,26H,7-10H2,1H3,(H,22,25)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.60n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213163
PNG
(US9278963, 010)
Show SMILES ONC(=O)c1cnc(NC2(CCN(CC2)C(=O)Nc2ccccc2F)c2ccccc2)nc1
Show InChI InChI=1S/C23H23FN6O3/c24-18-8-4-5-9-19(18)27-22(32)30-12-10-23(11-13-30,17-6-2-1-3-7-17)28-21-25-14-16(15-26-21)20(31)29-33/h1-9,14-15,33H,10-13H2,(H,27,32)(H,29,31)(H,25,26,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.70n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213169
PNG
(US9278963, 016)
Show SMILES CNC(=O)N1CCC(CC1)(Nc1ncc(cn1)C(=O)NO)c1ccccc1
Show InChI InChI=1S/C18H22N6O3/c1-19-17(26)24-9-7-18(8-10-24,14-5-3-2-4-6-14)22-16-20-11-13(12-21-16)15(25)23-27/h2-6,11-12,27H,7-10H2,1H3,(H,19,26)(H,23,25)(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.70n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213154
PNG
(US9278963, 001)
Show SMILES ONC(=O)c1cnc(NC2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)nc1
Show InChI InChI=1S/C23H24N6O3/c30-20(28-32)17-15-24-21(25-16-17)27-23(18-7-3-1-4-8-18)11-13-29(14-12-23)22(31)26-19-9-5-2-6-10-19/h1-10,15-16,32H,11-14H2,(H,26,31)(H,28,30)(H,24,25,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.90n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213179
PNG
(US9278963, 028)
Show SMILES ONC(=O)c1cnc(NC2(CCN(CC2)C(=O)Cc2c[nH]c3ccccc23)c2ccccc2)nc1
Show InChI InChI=1S/C26H26N6O3/c33-23(14-18-15-27-22-9-5-4-8-21(18)22)32-12-10-26(11-13-32,20-6-2-1-3-7-20)30-25-28-16-19(17-29-25)24(34)31-35/h1-9,15-17,27,35H,10-14H2,(H,31,34)(H,28,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139273
PNG
(US8614223, 49)
Show SMILES COc1cc(F)ccc1CNc1ncc(cn1)C(=O)NO
Show InChI InChI=1S/C13H13FN4O3/c1-21-11-4-10(14)3-2-8(11)5-15-13-16-6-9(7-17-13)12(19)18-20/h2-4,6-7,20H,5H2,1H3,(H,18,19)(H,15,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139260
PNG
(US8614223, 36)
Show SMILES ONC(=O)c1cnc(NCc2ccc(Cl)cc2)nc1
Show InChI InChI=1S/C12H11ClN4O2/c13-10-3-1-8(2-4-10)5-14-12-15-6-9(7-16-12)11(18)17-19/h1-4,6-7,19H,5H2,(H,17,18)(H,14,15,16)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139259
PNG
(US8614223, 35)
Show SMILES ONC(=O)c1cnc(NCc2ccccc2)nc1
Show InChI InChI=1S/C12H12N4O2/c17-11(16-18)10-7-14-12(15-8-10)13-6-9-4-2-1-3-5-9/h1-5,7-8,18H,6H2,(H,16,17)(H,13,14,15)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139257
PNG
(US8614223, 33)
Show SMILES ONC(=O)c1cnc(NCc2ccccc2Cl)nc1
Show InChI InChI=1S/C12H11ClN4O2/c13-10-4-2-1-3-8(10)5-14-12-15-6-9(7-16-12)11(18)17-19/h1-4,6-7,19H,5H2,(H,17,18)(H,14,15,16)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139256
PNG
(US8614223, 32 | US8614223, 67)
Show SMILES CC(Nc1ncc(cn1)C(=O)NO)c1ccccc1
Show InChI InChI=1S/C13H14N4O2/c1-9(10-5-3-2-4-6-10)16-13-14-7-11(8-15-13)12(18)17-19/h2-9,19H,1H3,(H,17,18)(H,14,15,16)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139329
PNG
(US8614223, 107)
Show SMILES ONC(=O)c1cnc(NCc2ccc(cc2)-c2ccccc2)nc1
Show InChI InChI=1S/C18H16N4O2/c23-17(22-24)16-11-20-18(21-12-16)19-10-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9,11-12,24H,10H2,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139324
PNG
(US8614223, 102)
Show SMILES ONC(=O)c1cnc(NC2(CC2)c2cc3ccccc3s2)nc1
Show InChI InChI=1S/C16H14N4O2S/c21-14(20-22)11-8-17-15(18-9-11)19-16(5-6-16)13-7-10-3-1-2-4-12(10)23-13/h1-4,7-9,22H,5-6H2,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139319
PNG
(US8614223, 97)
Show SMILES OCc1ccc(cc1)C1(CC1)Nc1ncc(cn1)C(=O)NO
Show InChI InChI=1S/C15H16N4O3/c20-9-10-1-3-12(4-2-10)15(5-6-15)18-14-16-7-11(8-17-14)13(21)19-22/h1-4,7-8,20,22H,5-6,9H2,(H,19,21)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139316
PNG
(US8614223, 94)
Show SMILES ONC(=O)c1cnc(NC2(CC2)c2cccc(Cl)c2)nc1
Show InChI InChI=1S/C14H13ClN4O2/c15-11-3-1-2-10(6-11)14(4-5-14)18-13-16-7-9(8-17-13)12(20)19-21/h1-3,6-8,21H,4-5H2,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213167
PNG
(US9278963, 014)
Show SMILES ONC(=O)c1cnc(NC2(CCN(CC2)C(=O)Nc2ccc(F)cc2)c2ccccc2)nc1
Show InChI InChI=1S/C23H23FN6O3/c24-18-6-8-19(9-7-18)27-22(32)30-12-10-23(11-13-30,17-4-2-1-3-5-17)28-21-25-14-16(15-26-21)20(31)29-33/h1-9,14-15,33H,10-13H2,(H,27,32)(H,29,31)(H,25,26,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213168
PNG
(US9278963, 015)
Show SMILES Cc1ccc(NC(=O)N2CCC(CC2)(Nc2ncc(cn2)C(=O)NO)c2ccccc2)cc1
Show InChI InChI=1S/C24H26N6O3/c1-17-7-9-20(10-8-17)27-23(32)30-13-11-24(12-14-30,19-5-3-2-4-6-19)28-22-25-15-18(16-26-22)21(31)29-33/h2-10,15-16,33H,11-14H2,1H3,(H,27,32)(H,29,31)(H,25,26,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139335
PNG
(US8614223, 121)
Show SMILES ONC(=O)c1cnc(NC2(CC2)c2cccc(c2)C(F)(F)F)nc1
Show InChI InChI=1S/C15H13F3N4O2/c16-15(17,18)11-3-1-2-10(6-11)14(4-5-14)21-13-19-7-9(8-20-13)12(23)22-24/h1-3,6-8,24H,4-5H2,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139339
PNG
(US8614223, 125)
Show SMILES ONC(=O)c1cnc(NC2(CC2)c2cccc(OC(F)(F)F)c2)nc1
Show InChI InChI=1S/C15H13F3N4O3/c16-15(17,18)25-11-3-1-2-10(6-11)14(4-5-14)21-13-19-7-9(8-20-13)12(23)22-24/h1-3,6-8,24H,4-5H2,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139340
PNG
(US8614223, 126)
Show SMILES ONC(=O)c1cnc(NC2(CC2)c2cc(ccc2F)C(F)(F)F)nc1
Show InChI InChI=1S/C15H12F4N4O2/c16-11-2-1-9(15(17,18)19)5-10(11)14(3-4-14)22-13-20-6-8(7-21-13)12(24)23-25/h1-2,5-7,25H,3-4H2,(H,23,24)(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139341
PNG
(US8614223, 127)
Show SMILES Cc1ccccc1C1(CC1)Nc1ncc(cn1)C(=O)NO
Show InChI InChI=1S/C15H16N4O2/c1-10-4-2-3-5-12(10)15(6-7-15)18-14-16-8-11(9-17-14)13(20)19-21/h2-5,8-9,21H,6-7H2,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139342
PNG
(US8614223, 128)
Show SMILES ONC(=O)c1cnc(NC2(CC2)c2ccc3OCOc3c2)nc1
Show InChI InChI=1S/C15H14N4O4/c20-13(19-21)9-6-16-14(17-7-9)18-15(3-4-15)10-1-2-11-12(5-10)23-8-22-11/h1-2,5-7,21H,3-4,8H2,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139270
PNG
(US8614223, 46)
Show SMILES ONC(=O)c1cnc(NCc2ccc3OCOc3c2)nc1
Show InChI InChI=1S/C13H12N4O4/c18-12(17-19)9-5-15-13(16-6-9)14-4-8-1-2-10-11(3-8)21-7-20-10/h1-3,5-6,19H,4,7H2,(H,17,18)(H,14,15,16)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139264
PNG
(US8614223, 40)
Show SMILES ONC(=O)c1cnc(NCc2cccc(c2)C(F)(F)F)nc1
Show InChI InChI=1S/C13H11F3N4O2/c14-13(15,16)10-3-1-2-8(4-10)5-17-12-18-6-9(7-19-12)11(21)20-22/h1-4,6-7,22H,5H2,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139277
PNG
(US8614223, 53)
Show SMILES ONC(=O)c1cnc(NCc2ccc(F)c(Cl)c2)nc1
Show InChI InChI=1S/C12H10ClFN4O2/c13-9-3-7(1-2-10(9)14)4-15-12-16-5-8(6-17-12)11(19)18-20/h1-3,5-6,20H,4H2,(H,18,19)(H,15,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139283
PNG
(US8614223, 60)
Show SMILES ONC(=O)c1cnc(NC(c2ccccc2)c2ccccc2)nc1
Show InChI InChI=1S/C18H16N4O2/c23-17(22-24)15-11-19-18(20-12-15)21-16(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-12,16,24H,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139285
PNG
(US8614223, 62 | US8614223, 66)
Show SMILES C[C@@H](Nc1ncc(cn1)C(=O)NO)c1ccccc1
Show InChI InChI=1S/C13H14N4O2/c1-9(10-5-3-2-4-6-10)16-13-14-7-11(8-15-13)12(18)17-19/h2-9,19H,1H3,(H,17,18)(H,14,15,16)/t9-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139256
PNG
(US8614223, 32 | US8614223, 67)
Show SMILES CC(Nc1ncc(cn1)C(=O)NO)c1ccccc1
Show InChI InChI=1S/C13H14N4O2/c1-9(10-5-3-2-4-6-10)16-13-14-7-11(8-15-13)12(18)17-19/h2-9,19H,1H3,(H,17,18)(H,14,15,16)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139293
PNG
(US8614223, 71)
Show SMILES CC(C)(Nc1ncc(cn1)C(=O)NO)c1ccccc1F
Show InChI InChI=1S/C14H15FN4O2/c1-14(2,10-5-3-4-6-11(10)15)18-13-16-7-9(8-17-13)12(20)19-21/h3-8,21H,1-2H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139295
PNG
(US8614223, 73)
Show SMILES ONC(=O)c1cnc(NC2(CC2)c2ccccc2)nc1
Show InChI InChI=1S/C14H14N4O2/c19-12(18-20)10-8-15-13(16-9-10)17-14(6-7-14)11-4-2-1-3-5-11/h1-5,8-9,20H,6-7H2,(H,18,19)(H,15,16,17)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139302
PNG
(US8614223, 80)
Show SMILES CC(C)(Nc1ncc(cn1)C(=O)NO)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C14H14Cl2N4O2/c1-14(2,9-3-4-10(15)11(16)5-9)19-13-17-6-8(7-18-13)12(21)20-22/h3-7,22H,1-2H3,(H,20,21)(H,17,18,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139304
PNG
(US8614223, 82)
Show SMILES ONC(=O)c1cnc(NC2(CC2)c2ccccc2F)nc1
Show InChI InChI=1S/C14H13FN4O2/c15-11-4-2-1-3-10(11)14(5-6-14)18-13-16-7-9(8-17-13)12(20)19-21/h1-4,7-8,21H,5-6H2,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139309
PNG
(US8614223, 87)
Show SMILES ONC(=O)c1cnc(NC2(CC2)c2cccc(F)c2)nc1
Show InChI InChI=1S/C14H13FN4O2/c15-11-3-1-2-10(6-11)14(4-5-14)18-13-16-7-9(8-17-13)12(20)19-21/h1-3,6-8,21H,4-5H2,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139313
PNG
(US8614223, 91)
Show SMILES ONC(=O)c1cnc(NC2(CC2)c2ccccc2C(F)(F)F)nc1
Show InChI InChI=1S/C15H13F3N4O2/c16-15(17,18)11-4-2-1-3-10(11)14(5-6-14)21-13-19-7-9(8-20-13)12(23)22-24/h1-4,7-8,24H,5-6H2,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213162
PNG
(US9278963, 009)
Show SMILES ONC(=O)c1cnc(NC2(CCN(CC2)c2ccccc2)c2ccccc2)nc1
Show InChI InChI=1S/C22H23N5O2/c28-20(26-29)17-15-23-21(24-16-17)25-22(18-7-3-1-4-8-18)11-13-27(14-12-22)19-9-5-2-6-10-19/h1-10,15-16,29H,11-14H2,(H,26,28)(H,23,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.10n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213165
PNG
(US9278963, 012)
Show SMILES CN(C(=O)N1CCC(CC1)(Nc1ncc(cn1)C(=O)NO)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H26N6O3/c1-29(20-10-6-3-7-11-20)23(32)30-14-12-24(13-15-30,19-8-4-2-5-9-19)27-22-25-16-18(17-26-22)21(31)28-33/h2-11,16-17,33H,12-15H2,1H3,(H,28,31)(H,25,26,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.20n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213170
PNG
(US9278963, 017)
Show SMILES ONC(=O)c1cnc(NC2(CCN(CC2)C(=S)Nc2ccccc2)c2ccccc2)nc1
Show InChI InChI=1S/C23H24N6O2S/c30-20(28-31)17-15-24-21(25-16-17)27-23(18-7-3-1-4-8-18)11-13-29(14-12-23)22(32)26-19-9-5-2-6-10-19/h1-10,15-16,31H,11-14H2,(H,26,32)(H,28,30)(H,24,25,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.40n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM249365
PNG
(US9464073, 002)
Show SMILES ONC(=O)c1cnc(NC2(CCOCC2)c2cc(F)ccc2F)nc1
Show InChI InChI=1S/C16H16F2N4O3/c17-11-1-2-13(18)12(7-11)16(3-5-25-6-4-16)21-15-19-8-10(9-20-15)14(23)22-24/h1-2,7-9,24H,3-6H2,(H,22,23)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.40n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US9464073 (2016)


BindingDB Entry DOI: 10.7270/Q2TD9W8Z
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213166
PNG
(US9278963, 013)
Show SMILES ONC(=O)c1cnc(NC2(CCN(CC2)C(=O)Nc2cccc(F)c2)c2ccccc2)nc1
Show InChI InChI=1S/C23H23FN6O3/c24-18-7-4-8-19(13-18)27-22(32)30-11-9-23(10-12-30,17-5-2-1-3-6-17)28-21-25-14-16(15-26-21)20(31)29-33/h1-8,13-15,33H,9-12H2,(H,27,32)(H,29,31)(H,25,26,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.5n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213155
PNG
(US9278963, 002)
Show SMILES ONC(=O)c1cnc(NC2(CCN(CC2)C(=O)OCc2ccccc2)c2ccccc2)nc1
Show InChI InChI=1S/C24H25N5O4/c30-21(28-32)19-15-25-22(26-16-19)27-24(20-9-5-2-6-10-20)11-13-29(14-12-24)23(31)33-17-18-7-3-1-4-8-18/h1-10,15-16,32H,11-14,17H2,(H,28,30)(H,25,26,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.60n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213179
PNG
(US9278963, 028)
Show SMILES ONC(=O)c1cnc(NC2(CCN(CC2)C(=O)Cc2c[nH]c3ccccc23)c2ccccc2)nc1
Show InChI InChI=1S/C26H26N6O3/c33-23(14-18-15-27-22-9-5-4-8-21(18)22)32-12-10-26(11-13-32,20-6-2-1-3-7-20)30-25-28-16-19(17-29-25)24(34)31-35/h1-9,15-17,27,35H,10-14H2,(H,31,34)(H,28,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.80n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM249364
PNG
(US9464073, 001)
Show SMILES ONC(=O)c1cnc(NC2(CCCCC2)c2cc(F)cc(F)c2)nc1
Show InChI InChI=1S/C17H18F2N4O2/c18-13-6-12(7-14(19)8-13)17(4-2-1-3-5-17)22-16-20-9-11(10-21-16)15(24)23-25/h6-10,25H,1-5H2,(H,23,24)(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.90n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US9464073 (2016)


BindingDB Entry DOI: 10.7270/Q2TD9W8Z
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM213157
PNG
(US9278963, 004)
Show SMILES CCON1CCC(CC1)(Nc1ncc(cn1)C(=O)NO)c1ccccc1
Show InChI InChI=1S/C18H23N5O3/c1-2-26-23-10-8-18(9-11-23,15-6-4-3-5-7-15)21-17-19-12-14(13-20-17)16(24)22-25/h3-7,12-13,25H,2,8-11H2,1H3,(H,22,24)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.90n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
The compounds were diluted in assay buffer (50 mM HEPES, pH 7.4, 100 mM KCl, 0.001% Tween-20, 0.05% BSA, 20 uM TCEP) to 6 fold their final concentrat...


US Patent US9278963 (2016)


BindingDB Entry DOI: 10.7270/Q2GT5M0K
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139362
PNG
(US8614223, 148)
Show SMILES ONC(=O)c1cnc(NC2(CCCC2)c2ccc(F)cc2)nc1
Show InChI InChI=1S/C16H17FN4O2/c17-13-5-3-12(4-6-13)16(7-1-2-8-16)20-15-18-9-11(10-19-15)14(22)21-23/h3-6,9-10,23H,1-2,7-8H2,(H,21,22)(H,18,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139247
PNG
(US8614223, 23)
Show SMILES COc1cc(Nc2ncc(cn2)C(=O)NO)cc(OC)c1
Show InChI InChI=1S/C13H14N4O4/c1-20-10-3-9(4-11(5-10)21-2)16-13-14-6-8(7-15-13)12(18)17-19/h3-7,19H,1-2H3,(H,17,18)(H,14,15,16)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM139246
PNG
(US8614223, 22)
Show SMILES ONC(=O)c1cnc(Nc2cccc(c2)C(F)(F)F)nc1
Show InChI InChI=1S/C12H9F3N4O2/c13-12(14,15)8-2-1-3-9(4-8)18-11-16-5-7(6-17-11)10(20)19-21/h1-6,21H,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3n/an/an/an/an/an/a



Acetylon Pharmaceuticals, Inc.

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 701 total )  |  Next  |  Last  >>
Jump to: