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Compile Data Set for Download or QSAR

Found 45 hits from Albert Einstein College of Medicine of Yeshiva University   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50246593
PNG
(7-((1,3-dihydroxypropan-2-ylamino)methyl)-3H-pyrro...)
Show SMILES OCC(CO)NCc1c[nH]c2c1nc[nH]c2=O
Show InChI InChI=1S/C10H14N4O3/c15-3-7(4-16)11-1-6-2-12-9-8(6)13-5-14-10(9)17/h2,5,7,11-12,15-16H,1,3-4H2,(H,13,14,17)
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0.00520n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Equilibrium binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50246590
PNG
(7-(((3R,4S)-3-hydroxy-4-(propylthiomethyl)pyrrolid...)
Show SMILES CCCSC[C@H]1CN(Cc2c[nH]c3c2nc[nH]c3=O)C[C@@H]1O
Show InChI InChI=1S/C15H22N4O2S/c1-2-3-22-8-11-6-19(7-12(11)20)5-10-4-16-14-13(10)17-9-18-15(14)21/h4,9,11-12,16,20H,2-3,5-8H2,1H3,(H,17,18,21)/t11-,12+/m1/s1
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0.00980n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Equilibrium binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM22109
PNG
(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Show SMILES OC[C@H]1CN(Cc2c[nH]c3c2nc[nH]c3=O)C[C@@H]1O
Show InChI InChI=1S/C12H16N4O3/c17-5-8-3-16(4-9(8)18)2-7-1-13-11-10(7)14-6-15-12(11)19/h1,6,8-9,13,17-18H,2-5H2,(H,14,15,19)/t8-,9+/m1/s1
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0.0107n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Equilibrium binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50247151
PNG
(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)
Show SMILES CSC[C@H]1CN(Cc2c[nH]c3c2nc[nH]c3=O)C[C@@H]1O
Show InChI InChI=1S/C13H18N4O2S/c1-20-6-9-4-17(5-10(9)18)3-8-2-14-12-11(8)15-7-16-13(12)19/h2,7,9-10,14,18H,3-6H2,1H3,(H,15,16,19)/t9-,10+/m1/s1
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0.0196n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Equilibrium binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50195587
PNG
(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)
Show SMILES OC[C@H]1N[C@H]([C@H](O)[C@@H]1O)c1c[nH]c2c1nc[nH]c2=O
Show InChI InChI=1S/C11H14N4O4/c16-2-5-9(17)10(18)7(15-5)4-1-12-8-6(4)13-3-14-11(8)19/h1,3,5,7,9-10,12,15-18H,2H2,(H,13,14,19)/t5-,7+,9-,10+/m1/s1
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0.0579n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Equilibrium binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50247151
PNG
(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)
Show SMILES CSC[C@H]1CN(Cc2c[nH]c3c2nc[nH]c3=O)C[C@@H]1O
Show InChI InChI=1S/C13H18N4O2S/c1-20-6-9-4-17(5-10(9)18)3-8-2-14-12-11(8)15-7-16-13(12)19/h2,7,9-10,14,18H,3-6H2,1H3,(H,15,16,19)/t9-,10+/m1/s1
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0.100n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Initial binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50246593
PNG
(7-((1,3-dihydroxypropan-2-ylamino)methyl)-3H-pyrro...)
Show SMILES OCC(CO)NCc1c[nH]c2c1nc[nH]c2=O
Show InChI InChI=1S/C10H14N4O3/c15-3-7(4-16)11-1-6-2-12-9-8(6)13-5-14-10(9)17/h2,5,7,11-12,15-16H,1,3-4H2,(H,13,14,17)
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0.110n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Initial binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50246590
PNG
(7-(((3R,4S)-3-hydroxy-4-(propylthiomethyl)pyrrolid...)
Show SMILES CCCSC[C@H]1CN(Cc2c[nH]c3c2nc[nH]c3=O)C[C@@H]1O
Show InChI InChI=1S/C15H22N4O2S/c1-2-3-22-8-11-6-19(7-12(11)20)5-10-4-16-14-13(10)17-9-18-15(14)21/h4,9,11-12,16,20H,2-3,5-8H2,1H3,(H,17,18,21)/t11-,12+/m1/s1
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0.117n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Initial binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM22109
PNG
(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Show SMILES OC[C@H]1CN(Cc2c[nH]c3c2nc[nH]c3=O)C[C@@H]1O
Show InChI InChI=1S/C12H16N4O3/c17-5-8-3-16(4-9(8)18)2-7-1-13-11-10(7)14-6-15-12(11)19/h1,6,8-9,13,17-18H,2-5H2,(H,14,15,19)/t8-,9+/m1/s1
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1.10n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Initial binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50195587
PNG
(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)
Show SMILES OC[C@H]1N[C@H]([C@H](O)[C@@H]1O)c1c[nH]c2c1nc[nH]c2=O
Show InChI InChI=1S/C11H14N4O4/c16-2-5-9(17)10(18)7(15-5)4-1-12-8-6(4)13-3-14-11(8)19/h1,3,5,7,9-10,12,15-18H,2H2,(H,13,14,19)/t5-,7+,9-,10+/m1/s1
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3.30n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Initial binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50246594
PNG
((+/-)-7-((1-hydroxy-3-(methylthio)propan-2-ylamino...)
Show SMILES CSCC(CO)NCc1c[nH]c2c1nc[nH]c2=O
Show InChI InChI=1S/C11H16N4O2S/c1-18-5-8(4-16)12-2-7-3-13-10-9(7)14-6-15-11(10)17/h3,6,8,12-13,16H,2,4-5H2,1H3,(H,14,15,17)
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4.30n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Initial binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50246591
PNG
((+/-)-5'-deoxy-4'-fluoro-5'-methylthio-DADMe-ImmH ...)
Show SMILES CSC[C@@]1(F)CN(Cc2c[nH]c3c2nc[nH]c3=O)C[C@@H]1O
Show InChI InChI=1S/C13H17FN4O2S/c1-21-6-13(14)5-18(4-9(13)19)3-8-2-15-11-10(8)16-7-17-12(11)20/h2,7,9,15,19H,3-6H2,1H3,(H,16,17,20)/t9-,13-/m0/s1
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5.80n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Initial binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50246592
PNG
(5'-deoxy-4'-hydroxy-5'-methylthio-DADMe-ImmH | CHE...)
Show SMILES CSC[C@@]1(O)CN(Cc2c[nH]c3c2nc[nH]c3=O)C[C@@H]1O
Show InChI InChI=1S/C13H18N4O3S/c1-21-6-13(20)5-17(4-9(13)18)3-8-2-14-11-10(8)15-7-16-12(11)19/h2,7,9,14,18,20H,3-6H2,1H3,(H,15,16,19)/t9-,13-/m0/s1
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7.90n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Initial binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50247149
PNG
(5'-Methylthio-ImmH | CHEMBL473929 | US9290501, (A))
Show SMILES CSC[C@H]1N[C@H]([C@H](O)[C@@H]1O)c1c[nH]c2c1nc[nH]c2=O
Show InChI InChI=1S/C12H16N4O3S/c1-20-3-6-10(17)11(18)8(16-6)5-2-13-9-7(5)14-4-15-12(9)19/h2,4,6,8,10-11,13,16-18H,3H2,1H3,(H,14,15,19)/t6-,8+,10-,11+/m1/s1
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101n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Initial binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Purine nucleoside phosphorylase


(Homo sapiens (human))
BDBM50247150
PNG
(5'-phenylthio-ImmH | CHEMBL474328 | US9290501, (B))
Show SMILES O[C@@H]1[C@@H](CSc2ccccc2)N[C@H]([C@@H]1O)c1c[nH]c2c1nc[nH]c2=O
Show InChI InChI=1S/C17H18N4O3S/c22-15-11(7-25-9-4-2-1-3-5-9)21-13(16(15)23)10-6-18-14-12(10)19-8-20-17(14)24/h1-6,8,11,13,15-16,18,21-23H,7H2,(H,19,20,24)/t11-,13+,15-,16+/m1/s1
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160n/an/an/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL


Assay Description
Initial binding affinity to wild type human PNP


Bioorg Med Chem Lett 18: 5900-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.047
BindingDB Entry DOI: 10.7270/Q2SX6F4H
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144817
PNG
(US8952150, 143)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccc(F)cc3)n2)cc1F
Show InChI InChI=1S/C36H36F2N8O5/c37-27-10-6-24(7-11-27)23-41-33(49)26-8-12-28(13-9-26)42-35-44-34(45-36(46-35)43-29-14-15-31(47)30(38)22-29)40-17-19-51-21-20-50-18-16-39-32(48)25-4-2-1-3-5-25/h1-15,22,47H,16-21,23H2,(H,39,48)(H,41,49)(H3,40,42,43,44,45,46)
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n/an/a 16.5n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144813
PNG
(US8952150, 118)
Show SMILES Oc1ccc(Nc2nc(NCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3)n2)cc1
Show InChI InChI=1S/C34H34N8O4/c43-29-17-15-28(16-18-29)39-34-41-32(36-20-22-46-21-19-35-30(44)25-9-5-2-6-10-25)40-33(42-34)38-27-13-11-26(12-14-27)31(45)37-23-24-7-3-1-4-8-24/h1-18,43H,19-23H2,(H,35,44)(H,37,45)(H3,36,38,39,40,41,42)
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n/an/a 20.9n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144810
PNG
(US8952150, 99)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccc(F)cc3)n2)cc1
Show InChI InChI=1S/C36H37FN8O5/c37-28-10-6-25(7-11-28)24-40-33(48)27-8-12-29(13-9-27)41-35-43-34(44-36(45-35)42-30-14-16-31(46)17-15-30)39-19-21-50-23-22-49-20-18-38-32(47)26-4-2-1-3-5-26/h1-17,46H,18-24H2,(H,38,47)(H,40,48)(H3,39,41,42,43,44,45)
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n/an/a 23.7n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144815
PNG
(US8952150, 136)
Show SMILES Oc1ccc(Nc2nc(NCCOCCNC(=O)c3ccc(F)cc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3)n2)cc1
Show InChI InChI=1S/C34H33FN8O4/c35-26-10-6-24(7-11-26)30(45)36-18-20-47-21-19-37-32-41-33(43-34(42-32)40-28-14-16-29(44)17-15-28)39-27-12-8-25(9-13-27)31(46)38-22-23-4-2-1-3-5-23/h1-17,44H,18-22H2,(H,36,45)(H,38,46)(H3,37,39,40,41,42,43)
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n/an/a 23.9n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144812
PNG
(US8952150, 110)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3F)n2)cc1
Show InChI InChI=1S/C36H37FN8O5/c37-31-9-5-4-8-27(31)24-40-33(48)26-10-12-28(13-11-26)41-35-43-34(44-36(45-35)42-29-14-16-30(46)17-15-29)39-19-21-50-23-22-49-20-18-38-32(47)25-6-2-1-3-7-25/h1-17,46H,18-24H2,(H,38,47)(H,40,48)(H3,39,41,42,43,44,45)
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n/an/a 31.3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144819
PNG
(US8952150, 147)
Show SMILES Oc1ccc(Nc2nc(NCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccc(F)cc3)n2)cc1
Show InChI InChI=1S/C34H33FN8O4/c35-26-10-6-23(7-11-26)22-38-31(46)25-8-12-27(13-9-25)39-33-41-32(42-34(43-33)40-28-14-16-29(44)17-15-28)37-19-21-47-20-18-36-30(45)24-4-2-1-3-5-24/h1-17,44H,18-22H2,(H,36,45)(H,38,46)(H3,37,39,40,41,42,43)
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n/an/a 31.7n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144814
PNG
(US8952150, 124)
Show SMILES CN(c1ccc(cc1)C(=O)NCc1ccccc1)c1nc(NCCOCCOCCNC(=O)c2ccccc2)nc(Nc2ccc(O)cc2)n1
Show InChI InChI=1S/C37H40N8O5/c1-45(31-16-12-29(13-17-31)34(48)40-26-27-8-4-2-5-9-27)37-43-35(42-36(44-37)41-30-14-18-32(46)19-15-30)39-21-23-50-25-24-49-22-20-38-33(47)28-10-6-3-7-11-28/h2-19,46H,20-26H2,1H3,(H,38,47)(H,40,48)(H2,39,41,42,43,44)
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n/an/a 34n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144816
PNG
(US8952150, 137)
Show SMILES COc1ccc(cc1)C(=O)NCCOCCNc1nc(Nc2ccc(O)cc2)nc(Nc2ccc(cc2)C(=O)NCc2ccccc2)n1
Show InChI InChI=1S/C35H36N8O5/c1-47-30-17-9-26(10-18-30)31(45)36-19-21-48-22-20-37-33-41-34(43-35(42-33)40-28-13-15-29(44)16-14-28)39-27-11-7-25(8-12-27)32(46)38-23-24-5-3-2-4-6-24/h2-18,44H,19-23H2,1H3,(H,36,45)(H,38,46)(H3,37,39,40,41,42,43)
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n/an/a 36.7n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144795
PNG
(US8952150, 22 | US8952150, 83)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3)n2)cc1
Show InChI InChI=1S/C36H38N8O5/c45-31-17-15-30(16-18-31)41-36-43-34(38-20-22-49-24-23-48-21-19-37-32(46)27-9-5-2-6-10-27)42-35(44-36)40-29-13-11-28(12-14-29)33(47)39-25-26-7-3-1-4-8-26/h1-18,45H,19-25H2,(H,37,46)(H,39,47)(H3,38,40,41,42,43,44)
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n/an/a 42.7n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144818
PNG
(US8952150, 146)
Show SMILES OC(=O)c1cc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccc(F)cc3)n2)ccc1O
Show InChI InChI=1S/C37H37FN8O7/c38-27-10-6-24(7-11-27)23-41-33(49)26-8-12-28(13-9-26)42-36-44-35(45-37(46-36)43-29-14-15-31(47)30(22-29)34(50)51)40-17-19-53-21-20-52-18-16-39-32(48)25-4-2-1-3-5-25/h1-15,22,47H,16-21,23H2,(H,39,48)(H,41,49)(H,50,51)(H3,40,42,43,44,45,46)
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n/an/a 44.8n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144811
PNG
(US8952150, 105)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3cccc(F)c3)n2)cc1
Show InChI InChI=1S/C36H37FN8O5/c37-28-8-4-5-25(23-28)24-40-33(48)27-9-11-29(12-10-27)41-35-43-34(44-36(45-35)42-30-13-15-31(46)16-14-30)39-18-20-50-22-21-49-19-17-38-32(47)26-6-2-1-3-7-26/h1-16,23,46H,17-22,24H2,(H,38,47)(H,40,48)(H3,39,41,42,43,44,45)
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n/an/a 47.5n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144801
PNG
(US8952150, 64)
Show SMILES O=C(NCCOCCOCCNc1nc(Nc2ccc(cc2)C(=O)NCc2ccccc2)nc(Nc2ccc3[nH]ncc3c2)n1)c1ccccc1
Show InChI InChI=1S/C37H38N10O4/c48-33(27-9-5-2-6-10-27)38-17-19-50-21-22-51-20-18-39-35-44-36(46-37(45-35)43-31-15-16-32-29(23-31)25-41-47-32)42-30-13-11-28(12-14-30)34(49)40-24-26-7-3-1-4-8-26/h1-16,23,25H,17-22,24H2,(H,38,48)(H,40,49)(H,41,47)(H3,39,42,43,44,45,46)
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n/an/a 115n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144790
PNG
(US8952150, 8 | US8952150, T26A)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCCOCCOCCN=[N+]=[N-])n2)cc1
Show InChI InChI=1S/C35H43N11O7/c36-46-40-17-21-53-25-24-51-19-15-38-32(49)27-6-8-28(9-7-27)41-34-43-33(44-35(45-34)42-29-10-12-30(47)13-11-29)39-16-20-52-23-22-50-18-14-37-31(48)26-4-2-1-3-5-26/h1-13,47H,14-25H2,(H,37,48)(H,38,49)(H3,39,41,42,43,44,45)
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n/an/a 224n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144790
PNG
(US8952150, 8 | US8952150, T26A)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCCOCCOCCN=[N+]=[N-])n2)cc1
Show InChI InChI=1S/C35H43N11O7/c36-46-40-17-21-53-25-24-51-19-15-38-32(49)27-6-8-28(9-7-27)41-34-43-33(44-35(45-34)42-29-10-12-30(47)13-11-29)39-16-20-52-23-22-50-18-14-37-31(48)26-4-2-1-3-5-26/h1-13,47H,14-25H2,(H,37,48)(H,38,49)(H3,39,41,42,43,44,45)
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n/an/a 378n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144795
PNG
(US8952150, 22 | US8952150, 83)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3)n2)cc1
Show InChI InChI=1S/C36H38N8O5/c45-31-17-15-30(16-18-31)41-36-43-34(38-20-22-49-24-23-48-21-19-37-32(46)27-9-5-2-6-10-27)42-35(44-36)40-29-13-11-28(12-14-29)33(47)39-25-26-7-3-1-4-8-26/h1-18,45H,19-25H2,(H,37,46)(H,39,47)(H3,38,40,41,42,43,44)
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n/an/a 609n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144809
PNG
(US8952150, 91)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccc(Cl)cc3)n2)cc1
Show InChI InChI=1S/C36H37ClN8O5/c37-28-10-6-25(7-11-28)24-40-33(48)27-8-12-29(13-9-27)41-35-43-34(44-36(45-35)42-30-14-16-31(46)17-15-30)39-19-21-50-23-22-49-20-18-38-32(47)26-4-2-1-3-5-26/h1-17,46H,18-24H2,(H,38,47)(H,40,48)(H3,39,41,42,43,44,45)
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n/an/a 620n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144807
PNG
(US8952150, 87)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3cccc(Cl)c3)n2)cc1
Show InChI InChI=1S/C36H37ClN8O5/c37-28-8-4-5-25(23-28)24-40-33(48)27-9-11-29(12-10-27)41-35-43-34(44-36(45-35)42-30-13-15-31(46)16-14-30)39-18-20-50-22-21-49-19-17-38-32(47)26-6-2-1-3-7-26/h1-16,23,46H,17-22,24H2,(H,38,47)(H,40,48)(H3,39,41,42,43,44,45)
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n/an/a 710n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144797
PNG
(US8952150, 44)
Show SMILES CCCCCCNC(=O)c1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(O)cc3)n2)cc1
Show InChI InChI=1S/C35H44N8O5/c1-2-3-4-8-19-36-32(46)27-11-13-28(14-12-27)39-34-41-33(42-35(43-34)40-29-15-17-30(44)18-16-29)38-21-23-48-25-24-47-22-20-37-31(45)26-9-6-5-7-10-26/h5-7,9-18,44H,2-4,8,19-25H2,1H3,(H,36,46)(H,37,45)(H3,38,39,40,41,42,43)
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n/an/a 760n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144808
PNG
(US8952150, 88)
Show SMILES COc1cccc(CNC(=O)c2ccc(Nc3nc(NCCOCCOCCNC(=O)c4ccccc4)nc(Nc4ccc(O)cc4)n3)cc2)c1
Show InChI InChI=1S/C37H40N8O6/c1-49-32-9-5-6-26(24-32)25-40-34(48)28-10-12-29(13-11-28)41-36-43-35(44-37(45-36)42-30-14-16-31(46)17-15-30)39-19-21-51-23-22-50-20-18-38-33(47)27-7-3-2-4-8-27/h2-17,24,46H,18-23,25H2,1H3,(H,38,47)(H,40,48)(H3,39,41,42,43,44,45)
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n/an/a 820n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144806
PNG
(US8952150, 86)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccc3-c3ccccc3)n2)cc1
Show InChI InChI=1S/C42H42N8O5/c51-36-21-19-35(20-22-36)47-42-49-40(44-24-26-55-28-27-54-25-23-43-38(52)31-11-5-2-6-12-31)48-41(50-42)46-34-17-15-32(16-18-34)39(53)45-29-33-13-7-8-14-37(33)30-9-3-1-4-10-30/h1-22,51H,23-29H2,(H,43,52)(H,45,53)(H3,44,46,47,48,49,50)
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n/an/a 870n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144803
PNG
(US8952150, 69)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)OCc3ccccc3)n2)cc1
Show InChI InChI=1S/C36H37N7O6/c44-31-17-15-30(16-18-31)40-36-42-34(38-20-22-48-24-23-47-21-19-37-32(45)27-9-5-2-6-10-27)41-35(43-36)39-29-13-11-28(12-14-29)33(46)49-25-26-7-3-1-4-8-26/h1-18,44H,19-25H2,(H,37,45)(H3,38,39,40,41,42,43)
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n/an/a 890n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144804
PNG
(US8952150, 70)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(cc3)C(=O)NCc3ccccn3)n2)cc1
Show InChI InChI=1S/C35H37N9O5/c45-30-15-13-28(14-16-30)41-35-43-33(38-19-21-49-23-22-48-20-18-37-31(46)25-6-2-1-3-7-25)42-34(44-35)40-27-11-9-26(10-12-27)32(47)39-24-29-8-4-5-17-36-29/h1-17,45H,18-24H2,(H,37,46)(H,39,47)(H3,38,40,41,42,43,44)
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n/an/a 1.05E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144796
PNG
(US8952150, 43)
Show SMILES COC(=O)CCCCCCNC(=O)c1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(O)cc3)n2)cc1
Show InChI InChI=1S/C37H46N8O7/c1-50-32(47)11-7-2-3-8-20-38-34(49)28-12-14-29(15-13-28)41-36-43-35(44-37(45-36)42-30-16-18-31(46)19-17-30)40-22-24-52-26-25-51-23-21-39-33(48)27-9-5-4-6-10-27/h4-6,9-10,12-19,46H,2-3,7-8,11,20-26H2,1H3,(H,38,49)(H,39,48)(H3,40,41,42,43,44,45)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144802
PNG
(US8952150, 65)
Show SMILES CCCCCCNC(=O)c1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc4[nH]ncc4c3)n2)cc1
Show InChI InChI=1S/C36H44N10O4/c1-2-3-4-8-17-37-33(48)27-11-13-29(14-12-27)41-35-43-34(44-36(45-35)42-30-15-16-31-28(24-30)25-40-46-31)39-19-21-50-23-22-49-20-18-38-32(47)26-9-6-5-7-10-26/h5-7,9-16,24-25H,2-4,8,17-23H2,1H3,(H,37,48)(H,38,47)(H,40,46)(H3,39,41,42,43,44,45)
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n/an/a 1.38E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144800
PNG
(US8952150, 59)
Show SMILES Oc1ccc(Nc2nc(NCCOCCNC(=O)c3ccccc3)nc(Nc3ccccc3)n2)cc1
Show InChI InChI=1S/C26H27N7O3/c34-22-13-11-21(12-14-22)30-26-32-24(31-25(33-26)29-20-9-5-2-6-10-20)28-16-18-36-17-15-27-23(35)19-7-3-1-4-8-19/h1-14,34H,15-18H2,(H,27,35)(H3,28,29,30,31,32,33)
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n/an/a 2.46E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144798
PNG
(US8952150, 53)
Show SMILES O=C(NCCOCCOCCNc1nc(Nc2ccccc2)nc(Nc2ccc3cn[nH]c3c2)n1)c1ccccc1
Show InChI InChI=1S/C29H31N9O3/c39-26(21-7-3-1-4-8-21)30-13-15-40-17-18-41-16-14-31-27-35-28(33-23-9-5-2-6-10-23)37-29(36-27)34-24-12-11-22-20-32-38-25(22)19-24/h1-12,19-20H,13-18H2,(H,30,39)(H,32,38)(H3,31,33,34,35,36,37)
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n/an/a 4.04E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144791
PNG
(US8952150, 4)
Show SMILES Oc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccccc3)n2)cc1
Show InChI InChI=1S/C28H31N7O4/c36-24-13-11-23(12-14-24)32-28-34-26(33-27(35-28)31-22-9-5-2-6-10-22)30-16-18-39-20-19-38-17-15-29-25(37)21-7-3-1-4-8-21/h1-14,36H,15-20H2,(H,29,37)(H3,30,31,32,33,34,35)
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n/an/a 4.85E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144799
PNG
(US8952150, 57)
Show SMILES OC(=O)Cc1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccccc3)n2)cc1
Show InChI InChI=1S/C30H33N7O5/c38-26(39)21-22-11-13-25(14-12-22)34-30-36-28(35-29(37-30)33-24-9-5-2-6-10-24)32-16-18-42-20-19-41-17-15-31-27(40)23-7-3-1-4-8-23/h1-14H,15-21H2,(H,31,40)(H,38,39)(H3,32,33,34,35,36,37)
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n/an/a 5.57E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144794
PNG
(US8952150, 17)
Show SMILES COC(=O)c1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(O)cc3)n2)cc1
Show InChI InChI=1S/C30H33N7O6/c1-41-27(40)22-7-9-23(10-8-22)33-29-35-28(36-30(37-29)34-24-11-13-25(38)14-12-24)32-16-18-43-20-19-42-17-15-31-26(39)21-5-3-2-4-6-21/h2-14,38H,15-20H2,1H3,(H,31,39)(H3,32,33,34,35,36,37)
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n/an/a 6.57E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair
Prostaglandin transporter (PGT)


(Rattus norvegicus (Rat))
BDBM144793
PNG
(US8952150, 16)
Show SMILES CC(C)(C)NC(=O)c1ccc(Nc2nc(NCCOCCOCCNC(=O)c3ccccc3)nc(Nc3ccc(O)cc3)n2)cc1
Show InChI InChI=1S/C33H40N8O5/c1-33(2,3)41-29(44)24-9-11-25(12-10-24)36-31-38-30(39-32(40-31)37-26-13-15-27(42)16-14-26)35-18-20-46-22-21-45-19-17-34-28(43)23-7-5-4-6-8-23/h4-16,42H,17-22H2,1-3H3,(H,34,43)(H,41,44)(H3,35,36,37,38,39,40)
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n/an/a 9.77E+3n/an/an/an/an/an/a



Albert Einstein College of Medicine of Yeshiva University

US Patent


Assay Description
MDCK cells stably transfected with rat PGT (Endo et al., 2002) were seeded at 15-20% confluence on 24-well plates. The day on which the cells were se...


US Patent US8952150 (2015)


BindingDB Entry DOI: 10.7270/Q2VD6X56
More data for this
Ligand-Target Pair