BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 64 hits from Alexander Technological Education Institute of Thessaloniki   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359885
PNG
(CHEMBL409741)
Show SMILES Clc1ccccc1\C=C1/S\C(NC1=O)=N\c1nc2ccccc2s1
Show InChI InChI=1S/C17H10ClN3OS2/c18-11-6-2-1-5-10(11)9-14-15(22)20-17(24-14)21-16-19-12-7-3-4-8-13(12)23-16/h1-9H,(H,19,20,21,22)/b14-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Cyclooxygenase


(Homo sapiens (human))
BDBM11639
PNG
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of human recombinant COX-2 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359883
PNG
(CHEMBL407152)
Show SMILES [O-][N+](=O)c1cccc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)c1
Show InChI InChI=1S/C17H10N4O3S2/c22-15-14(9-10-4-3-5-11(8-10)21(23)24)26-17(19-15)20-16-18-12-6-1-2-7-13(12)25-16/h1-9H,(H,18,19,20,22)/b14-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 310n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359887
PNG
(CHEMBL259902)
Show SMILES Clc1ccc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)cc1
Show InChI InChI=1S/C17H10ClN3OS2/c18-11-7-5-10(6-8-11)9-14-15(22)20-17(24-14)21-16-19-12-3-1-2-4-13(12)23-16/h1-9H,(H,19,20,21,22)/b14-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 310n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359884
PNG
(CHEMBL409276)
Show SMILES [O-][N+](=O)c1ccc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)cc1
Show InChI InChI=1S/C17H10N4O3S2/c22-15-14(9-10-5-7-11(8-6-10)21(23)24)26-17(19-15)20-16-18-12-3-1-2-4-13(12)25-16/h1-9H,(H,18,19,20,22)/b14-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 510n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359893
PNG
(CHEMBL260063)
Show SMILES O=C1N\C(S\C1=C/c1ccccc1)=N/c1nc2ccccc2s1
Show InChI InChI=1S/C17H11N3OS2/c21-15-14(10-11-6-2-1-3-7-11)23-17(19-15)20-16-18-12-8-4-5-9-13(12)22-16/h1-10H,(H,18,19,20,21)/b14-10-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359888
PNG
(CHEMBL1929524)
Show SMILES Oc1cccc(\C=C2/S\C(NC2=O)=N/c2nc3ccccc3s2)c1
Show InChI InChI=1S/C17H11N3O2S2/c21-11-5-3-4-10(8-11)9-14-15(22)19-17(24-14)20-16-18-12-6-1-2-7-13(12)23-16/h1-9,21H,(H,18,19,20,22)/b14-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.61E+3n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359889
PNG
(CHEMBL259883)
Show SMILES Oc1ccc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)cc1
Show InChI InChI=1S/C17H11N3O2S2/c21-11-7-5-10(6-8-11)9-14-15(22)19-17(24-14)20-16-18-12-3-1-2-4-13(12)23-16/h1-9,21H,(H,18,19,20,22)/b14-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.91E+3n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359900
PNG
(CHEMBL260125)
Show SMILES Oc1ccc(\C=C2/S\C(NC2=O)=N/c2nsc3ccccc23)cc1
Show InChI InChI=1S/C17H11N3O2S2/c21-11-7-5-10(6-8-11)9-14-16(22)19-17(23-14)18-15-12-3-1-2-4-13(12)24-20-15/h1-9,21H,(H,18,19,20,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.77E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50339185
PNG
((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)
Show SMILES COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
Show InChI InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.95E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359886
PNG
(CHEMBL261268)
Show SMILES Clc1cccc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)c1
Show InChI InChI=1S/C17H10ClN3OS2/c18-11-5-3-4-10(8-11)9-14-15(22)20-17(24-14)21-16-19-12-6-1-2-7-13(12)23-16/h1-9H,(H,19,20,21,22)/b14-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.24E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359892
PNG
(CHEMBL258735)
Show SMILES COc1ccc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)cc1
Show InChI InChI=1S/C18H13N3O2S2/c1-23-12-8-6-11(7-9-12)10-15-16(22)20-18(25-15)21-17-19-13-4-2-3-5-14(13)24-17/h2-10H,1H3,(H,19,20,21,22)/b15-10-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.82E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359899
PNG
(CHEMBL263909)
Show SMILES Clc1ccc(\C=C2/S\C(NC2=O)=N/c2nsc3ccccc23)cc1
Show InChI InChI=1S/C17H10ClN3OS2/c18-11-7-5-10(6-8-11)9-14-16(22)20-17(23-14)19-15-12-3-1-2-4-13(12)24-21-15/h1-9H,(H,19,20,21,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.82E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359894
PNG
(CHEMBL407151)
Show SMILES [O-][N+](=O)c1ccccc1\C=C1/S\C(NC1=O)=N/c1nsc2ccccc12
Show InChI InChI=1S/C17H10N4O3S2/c22-16-14(9-10-5-1-3-7-12(10)21(23)24)25-17(19-16)18-15-11-6-2-4-8-13(11)26-20-15/h1-9H,(H,18,19,20,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM22372
PNG
(4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...)
Show SMILES C[C@@H](Cc1ccc(O)c(O)c1)[C@H](C)Cc1ccc(O)c(O)c1
Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3/t11-,12+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.13E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359901
PNG
(CHEMBL260886)
Show SMILES COc1cc(\C=C2/S\C(NC2=O)=N/c2nsc3ccccc23)ccc1O
Show InChI InChI=1S/C18H13N3O3S2/c1-24-13-8-10(6-7-12(13)22)9-15-17(23)20-18(25-15)19-16-11-4-2-3-5-14(11)26-21-16/h2-9,22H,1H3,(H,19,20,21,23)/b15-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.39E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359891
PNG
(CHEMBL1926825)
Show SMILES COc1cc(\C=C2/S\C(NC2=O)=N/c2nc3ccccc3s2)cc(OC)c1O
Show InChI InChI=1S/C19H15N3O4S2/c1-25-12-7-10(8-13(26-2)16(12)23)9-15-17(24)21-19(28-15)22-18-20-11-5-3-4-6-14(11)27-18/h3-9,23H,1-2H3,(H,20,21,22,24)/b15-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.39E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM11639
PNG
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 3.45E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359888
PNG
(CHEMBL1929524)
Show SMILES Oc1cccc(\C=C2/S\C(NC2=O)=N/c2nc3ccccc3s2)c1
Show InChI InChI=1S/C17H11N3O2S2/c21-11-5-3-4-10(8-11)9-14-15(22)19-17(24-14)20-16-18-12-6-1-2-7-13(12)23-16/h1-9,21H,(H,18,19,20,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.47E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359890
PNG
(CHEMBL263119)
Show SMILES COc1cc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)ccc1O
Show InChI InChI=1S/C18H13N3O3S2/c1-24-13-8-10(6-7-12(13)22)9-15-16(23)20-18(26-15)21-17-19-11-4-2-3-5-14(11)25-17/h2-9,22H,1H3,(H,19,20,21,23)/b15-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.55E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359882
PNG
(CHEMBL260059)
Show SMILES [O-][N+](=O)c1ccccc1\C=C1/S\C(NC1=O)=N\c1nc2ccccc2s1
Show InChI InChI=1S/C17H10N4O3S2/c22-15-14(9-10-5-1-3-7-12(10)21(23)24)26-17(19-15)20-16-18-11-6-2-4-8-13(11)25-16/h1-9H,(H,18,19,20,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.55E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359886
PNG
(CHEMBL261268)
Show SMILES Clc1cccc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)c1
Show InChI InChI=1S/C17H10ClN3OS2/c18-11-5-3-4-10(8-11)9-14-15(22)20-17(24-14)21-16-19-12-6-1-2-7-13(12)23-16/h1-9H,(H,19,20,21,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.55E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359894
PNG
(CHEMBL407151)
Show SMILES [O-][N+](=O)c1ccccc1\C=C1/S\C(NC1=O)=N/c1nsc2ccccc12
Show InChI InChI=1S/C17H10N4O3S2/c22-16-14(9-10-5-1-3-7-12(10)21(23)24)25-17(19-16)18-15-11-6-2-4-8-13(11)26-20-15/h1-9H,(H,18,19,20,22)/b14-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.55E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359889
PNG
(CHEMBL259883)
Show SMILES Oc1ccc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)cc1
Show InChI InChI=1S/C17H11N3O2S2/c21-11-7-5-10(6-8-11)9-14-15(22)19-17(24-14)20-16-18-12-3-1-2-4-13(12)23-16/h1-9,21H,(H,18,19,20,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.63E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359896
PNG
(CHEMBL410649)
Show SMILES [O-][N+](=O)c1ccc(\C=C2/S\C(NC2=O)=N/c2nsc3ccccc23)cc1
Show InChI InChI=1S/C17H10N4O3S2/c22-16-14(9-10-5-7-11(8-6-10)21(23)24)25-17(19-16)18-15-12-3-1-2-4-13(12)26-20-15/h1-9H,(H,18,19,20,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.66E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359890
PNG
(CHEMBL263119)
Show SMILES COc1cc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)ccc1O
Show InChI InChI=1S/C18H13N3O3S2/c1-24-13-8-10(6-7-12(13)22)9-15-16(23)20-18(26-15)21-17-19-11-4-2-3-5-14(11)25-17/h2-9,22H,1H3,(H,19,20,21,23)/b15-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.98E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359883
PNG
(CHEMBL407152)
Show SMILES [O-][N+](=O)c1cccc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)c1
Show InChI InChI=1S/C17H10N4O3S2/c22-15-14(9-10-4-3-5-11(8-10)21(23)24)26-17(19-15)20-16-18-12-6-1-2-7-13(12)25-16/h1-9H,(H,18,19,20,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.20E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359897
PNG
(CHEMBL264164)
Show SMILES Clc1ccccc1\C=C1/S\C(NC1=O)=N/c1nsc2ccccc12
Show InChI InChI=1S/C17H10ClN3OS2/c18-12-7-3-1-5-10(12)9-14-16(22)20-17(23-14)19-15-11-6-2-4-8-13(11)24-21-15/h1-9H,(H,19,20,21,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.36E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359887
PNG
(CHEMBL259902)
Show SMILES Clc1ccc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)cc1
Show InChI InChI=1S/C17H10ClN3OS2/c18-11-7-5-10(6-8-11)9-14-15(22)20-17(24-14)21-16-19-12-3-1-2-4-13(12)23-16/h1-9H,(H,19,20,21,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.00E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359884
PNG
(CHEMBL409276)
Show SMILES [O-][N+](=O)c1ccc(\C=C2/S\C(NC2=O)=N\c2nc3ccccc3s2)cc1
Show InChI InChI=1S/C17H10N4O3S2/c22-15-14(9-10-5-7-11(8-6-10)21(23)24)26-17(19-15)20-16-18-12-3-1-2-4-13(12)25-16/h1-9H,(H,18,19,20,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.01E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359899
PNG
(CHEMBL263909)
Show SMILES Clc1ccc(\C=C2/S\C(NC2=O)=N/c2nsc3ccccc23)cc1
Show InChI InChI=1S/C17H10ClN3OS2/c18-11-7-5-10(6-8-11)9-14-16(22)20-17(23-14)19-15-12-3-1-2-4-13(12)24-21-15/h1-9H,(H,19,20,21,22)/b14-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.24E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359896
PNG
(CHEMBL410649)
Show SMILES [O-][N+](=O)c1ccc(\C=C2/S\C(NC2=O)=N/c2nsc3ccccc23)cc1
Show InChI InChI=1S/C17H10N4O3S2/c22-16-14(9-10-5-7-11(8-6-10)21(23)24)25-17(19-16)18-15-12-3-1-2-4-13(12)26-20-15/h1-9H,(H,18,19,20,22)/b14-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.62E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359885
PNG
(CHEMBL409741)
Show SMILES Clc1ccccc1\C=C1/S\C(NC1=O)=N\c1nc2ccccc2s1
Show InChI InChI=1S/C17H10ClN3OS2/c18-11-6-2-1-5-10(11)9-14-15(22)20-17(24-14)21-16-19-12-7-3-4-8-13(12)23-16/h1-9H,(H,19,20,21,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.10E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359895
PNG
(CHEMBL261267)
Show SMILES [O-][N+](=O)c1cccc(\C=C2/S\C(NC2=O)=N/c2nsc3ccccc23)c1
Show InChI InChI=1S/C17H10N4O3S2/c22-16-14(9-10-4-3-5-11(8-10)21(23)24)25-17(19-16)18-15-12-6-1-2-7-13(12)26-20-15/h1-9H,(H,18,19,20,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.94E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM24518
PNG
((2E,5E)-5-[(3-nitrophenyl)methylidene]-2-(1,3-thia...)
Show SMILES [O-][N+](=O)c1cccc(\C=C2\S\C(NC2=O)=N\c2nccs2)c1
Show InChI InChI=1S/C13H8N4O3S2/c18-11-10(7-8-2-1-3-9(6-8)17(19)20)22-13(15-11)16-12-14-4-5-21-12/h1-7H,(H,14,15,16,18)/b10-7+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.91E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM24515
PNG
((2E,5E)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]...)
Show SMILES COc1cc(\C=C2\S\C(NC2=O)=N\c2nccs2)ccc1O
Show InChI InChI=1S/C14H11N3O3S2/c1-20-10-6-8(2-3-9(10)18)7-11-12(19)16-14(22-11)17-13-15-4-5-21-13/h2-7,18H,1H3,(H,15,16,17,19)/b11-7+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.95E+4n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359898
PNG
(CHEMBL412064)
Show SMILES Clc1cccc(\C=C2/S\C(NC2=O)=N/c2nsc3ccccc23)c1
Show InChI InChI=1S/C17H10ClN3OS2/c18-11-5-3-4-10(8-11)9-14-16(22)20-17(23-14)19-15-12-6-1-2-7-13(12)24-21-15/h1-9H,(H,19,20,21,22)/b14-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359902
PNG
(CHEMBL1926826)
Show SMILES COc1cc(\C=C2/S\C(NC2=O)=N\c2nsc3ccccc23)cc(OC)c1O
Show InChI InChI=1S/C19H15N3O4S2/c1-25-12-7-10(8-13(26-2)16(12)23)9-15-18(24)21-19(27-15)20-17-11-5-3-4-6-14(11)28-22-17/h3-9,23H,1-2H3,(H,20,21,22,24)/b15-9-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359893
PNG
(CHEMBL260063)
Show SMILES O=C1N\C(S\C1=C/c1ccccc1)=N/c1nc2ccccc2s1
Show InChI InChI=1S/C17H11N3OS2/c21-15-14(10-11-6-2-1-3-7-11)23-17(19-15)20-16-18-12-8-4-5-9-13(12)22-16/h1-10H,(H,18,19,20,21)/b14-10-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM24521
PNG
((2E,5E)-5-[(2-chlorophenyl)methylidene]-2-(1,3-thi...)
Show SMILES Clc1ccccc1\C=C1\S\C(NC1=O)=N\c1nccs1
Show InChI InChI=1S/C13H8ClN3OS2/c14-9-4-2-1-3-8(9)7-10-11(18)16-13(20-10)17-12-15-5-6-19-12/h1-7H,(H,15,16,17,18)/b10-7+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.15E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM24513
PNG
((2E,5E)-5-[(4-hydroxyphenyl)methylidene]-2-(1,3-th...)
Show SMILES Oc1ccc(\C=C2\S\C(NC2=O)=N\c2nccs2)cc1
Show InChI InChI=1S/C13H9N3O2S2/c17-9-3-1-8(2-4-9)7-10-11(18)15-13(20-10)16-12-14-5-6-19-12/h1-7,17H,(H,14,15,16,18)/b10-7+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.16E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM24519
PNG
((2E,5E)-5-[(4-chlorophenyl)methylidene]-2-(1,3-thi...)
Show SMILES Clc1ccc(\C=C2\S\C(NC2=O)=N\c2nccs2)cc1
Show InChI InChI=1S/C13H8ClN3OS2/c14-9-3-1-8(2-4-9)7-10-11(18)16-13(20-10)17-12-15-5-6-19-12/h1-7H,(H,15,16,17,18)/b10-7+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM50359904
PNG
(CHEMBL1926827)
Show SMILES COc1cc(\C=C2/S\C(NC2=O)=N/c2nccs2)cc(OC)c1O
Show InChI InChI=1S/C15H13N3O4S2/c1-21-9-5-8(6-10(22-2)12(9)19)7-11-13(20)17-15(24-11)18-14-16-3-4-23-14/h3-7,19H,1-2H3,(H,16,17,18,20)/b11-7-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.22E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM24520
PNG
((2E,5E)-5-[(3-chlorophenyl)methylidene]-2-(1,3-thi...)
Show SMILES Clc1cccc(\C=C2\S\C(NC2=O)=N\c2nccs2)c1
Show InChI InChI=1S/C13H8ClN3OS2/c14-9-3-1-2-8(6-9)7-10-11(18)16-13(20-10)17-12-15-4-5-19-12/h1-7H,(H,15,16,17,18)/b10-7+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.25E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Lipoxygenase-1


(Glycine max (soybean))
BDBM24520
PNG
((2E,5E)-5-[(3-chlorophenyl)methylidene]-2-(1,3-thi...)
Show SMILES Clc1cccc(\C=C2\S\C(NC2=O)=N\c2nccs2)c1
Show InChI InChI=1S/C13H8ClN3OS2/c14-9-3-1-2-8(6-9)7-10-11(18)16-13(20-10)17-12-15-4-5-19-12/h1-7H,(H,15,16,17,18)/b10-7+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.26E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of soybean LOX type 1 pre-incubated for 4 mins at 7x10'-7 w/v concentration assessed as inhibition of sodium linoleate to 13-hydroperoxyli...


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359895
PNG
(CHEMBL261267)
Show SMILES [O-][N+](=O)c1cccc(\C=C2/S\C(NC2=O)=N/c2nsc3ccccc23)c1
Show InChI InChI=1S/C17H10N4O3S2/c22-16-14(9-10-4-3-5-11(8-10)21(23)24)25-17(19-16)18-15-12-6-1-2-7-13(12)26-20-15/h1-9H,(H,18,19,20,22)/b14-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.26E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM24517
PNG
((2E,5E)-5-[(4-nitrophenyl)methylidene]-2-(1,3-thia...)
Show SMILES [O-][N+](=O)c1ccc(\C=C2\S\C(NC2=O)=N\c2nccs2)cc1
Show InChI InChI=1S/C13H8N4O3S2/c18-11-10(7-8-1-3-9(4-2-8)17(19)20)22-13(15-11)16-12-14-5-6-21-12/h1-7H,(H,14,15,16,18)/b10-7+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.41E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM24513
PNG
((2E,5E)-5-[(4-hydroxyphenyl)methylidene]-2-(1,3-th...)
Show SMILES Oc1ccc(\C=C2\S\C(NC2=O)=N\c2nccs2)cc1
Show InChI InChI=1S/C13H9N3O2S2/c17-9-3-1-8(2-4-9)7-10-11(18)15-13(20-10)16-12-14-5-6-19-12/h1-7,17H,(H,14,15,16,18)/b10-7+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.58E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359903
PNG
(CHEMBL409502)
Show SMILES O=C1N\C(S\C1=C/c1ccccc1)=N\c1nsc2ccccc12
Show InChI InChI=1S/C17H11N3OS2/c21-16-14(10-11-6-2-1-3-7-11)22-17(19-16)18-15-12-8-4-5-9-13(12)23-20-15/h1-10H,(H,18,19,20,21)/b14-10-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Ovis aries (Sheep))
BDBM50359902
PNG
(CHEMBL1926826)
Show SMILES COc1cc(\C=C2/S\C(NC2=O)=N\c2nsc3ccccc23)cc(OC)c1O
Show InChI InChI=1S/C19H15N3O4S2/c1-25-12-7-10(8-13(26-2)16(12)23)9-15-18(24)21-19(27-15)20-17-11-5-3-4-6-14(11)28-22-17/h3-9,23H,1-2H3,(H,20,21,22,24)/b15-9-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Alexander Technological Education Institute of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of ovine COX1 assessed as PGF2alpha production by enzyme immunoassay


Eur J Med Chem 47: 111-24 (2012)


Article DOI: 10.1016/j.ejmech.2011.10.029
BindingDB Entry DOI: 10.7270/Q2K937ZK
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 64 total )  |  Next  |  Last  >>
Jump to: