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Compile Data Set for Download or QSAR

Found 28 hits from Almirall Research Center   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31629
PNG
(Aminopyridine N-oxide, 55)
Show SMILES COc1cc(F)c(c(F)c1)-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C19H12F4N2O3/c1-28-10-7-14(22)16(15(23)8-10)18-17(24)12(4-5-25(18)27)19(26)11-3-2-9(20)6-13(11)21/h2-8H,24H2,1H3
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n/an/a 5n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31630
PNG
(Aminopyridine N-oxide, 56)
Show SMILES Cc1cc(O)ccc1-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C19H14F2N2O3/c1-10-8-12(24)3-5-13(10)18-17(22)15(6-7-23(18)26)19(25)14-4-2-11(20)9-16(14)21/h2-9,24H,22H2,1H3
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n/an/a 8n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31621
PNG
(Aminopyridine N-oxide, 47)
Show SMILES Nc1c(cc[n+]([O-])c1-c1c(Cl)cccc1Cl)C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C18H10Cl2F2N2O2/c19-12-2-1-3-13(20)15(12)17-16(23)11(6-7-24(17)26)18(25)10-5-4-9(21)8-14(10)22/h1-8H,23H2
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n/an/a 9n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31632
PNG
(Aminopyridine N-oxide, 58)
Show SMILES Cc1cc(OCCN2CCOCC2)ccc1-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C25H25F2N3O4/c1-16-14-18(34-13-10-29-8-11-33-12-9-29)3-5-19(16)24-23(28)21(6-7-30(24)32)25(31)20-4-2-17(26)15-22(20)27/h2-7,14-15H,8-13,28H2,1H3
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n/an/a 14n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31624
PNG
(Aminopyridine N-oxide, 50)
Show SMILES COc1cccc(OC)c1-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C20H16F2N2O4/c1-27-15-4-3-5-16(28-2)17(15)19-18(23)13(8-9-24(19)26)20(25)12-7-6-11(21)10-14(12)22/h3-10H,23H2,1-2H3
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n/an/a 15n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31623
PNG
(Aminopyridine N-oxide, 49)
Show SMILES Cc1cccc(C)c1-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C20H16F2N2O2/c1-11-4-3-5-12(2)17(11)19-18(23)15(8-9-24(19)26)20(25)14-7-6-13(21)10-16(14)22/h3-10H,23H2,1-2H3
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n/an/a 17n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31622
PNG
(Aminopyridine N-oxide, 48)
Show SMILES Nc1c(cc[n+]([O-])c1-c1c(F)cccc1F)C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C18H10F4N2O2/c19-9-4-5-10(14(22)8-9)18(25)11-6-7-24(26)17(16(11)23)15-12(20)2-1-3-13(15)21/h1-8H,23H2
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n/an/a 17n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31634
PNG
(Aminopyridine N-oxide, 60)
Show SMILES COCCOc1ccc(c(C)c1)-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C22H20F2N2O4/c1-13-11-15(30-10-9-29-2)4-6-16(13)21-20(25)18(7-8-26(21)28)22(27)17-5-3-14(23)12-19(17)24/h3-8,11-12H,9-10,25H2,1-2H3
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n/an/a 20n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31619
PNG
(Aminopyridine N-oxide, 45)
Show SMILES Cc1ccccc1-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C19H14F2N2O2/c1-11-4-2-3-5-13(11)18-17(22)15(8-9-23(18)25)19(24)14-7-6-12(20)10-16(14)21/h2-10H,22H2,1H3
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n/an/a 21n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31618
PNG
(Aminopyridine N-oxide, 44)
Show SMILES COc1ccccc1-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C19H14F2N2O3/c1-26-16-5-3-2-4-13(16)18-17(22)14(8-9-23(18)25)19(24)12-7-6-11(20)10-15(12)21/h2-10H,22H2,1H3
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n/an/a 23n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31612
PNG
(Aminopyridine N-oxide, 38)
Show SMILES Nc1c(cc[n+]([O-])c1-c1ccccc1Cl)C(=O)c1ccccc1Cl
Show InChI InChI=1S/C18H12Cl2N2O2/c19-14-7-3-1-5-11(14)17-16(21)13(9-10-22(17)24)18(23)12-6-2-4-8-15(12)20/h1-10H,21H2
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n/an/a 24n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31626
PNG
(Aminopyridine N-oxide, 52)
Show SMILES Nc1c(cc[n+]([O-])c1-c1cccc2OCOc12)C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C19H12F2N2O4/c20-10-4-5-11(14(21)8-10)18(24)12-6-7-23(25)17(16(12)22)13-2-1-3-15-19(13)27-9-26-15/h1-8H,9,22H2
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n/an/a 24n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31625
PNG
(Aminopyridine N-oxide, 51)
Show SMILES COc1cccc(c1OC)-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C20H16F2N2O4/c1-27-16-5-3-4-14(20(16)28-2)18-17(23)13(8-9-24(18)26)19(25)12-7-6-11(21)10-15(12)22/h3-10H,23H2,1-2H3
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n/an/a 37n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31628
PNG
(Aminopyridine N-oxide, 54)
Show SMILES Cc1cc(Cl)ccc1-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C19H13ClF2N2O2/c1-10-8-11(20)2-4-13(10)18-17(23)15(6-7-24(18)26)19(25)14-5-3-12(21)9-16(14)22/h2-9H,23H2,1H3
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n/an/a 38n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31615
PNG
(Aminopyridine N-oxide, 41)
Show SMILES Nc1c(cc[n+]([O-])c1-c1ccccc1Cl)C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C18H11ClF2N2O2/c19-14-4-2-1-3-11(14)17-16(22)13(7-8-23(17)25)18(24)12-6-5-10(20)9-15(12)21/h1-9H,22H2
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n/an/a 39n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31633
PNG
(Aminopyridine N-oxide, 59)
Show SMILES Cc1cc(ccc1-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C26H26F2N4O4/c1-16-14-17(26(34)30-7-9-31-10-12-36-13-11-31)2-4-19(16)24-23(29)21(6-8-32(24)35)25(33)20-5-3-18(27)15-22(20)28/h2-6,8,14-15H,7,9-13,29H2,1H3,(H,30,34)
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n/an/a 42n/an/an/an/a7.525



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Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31635
PNG
(Aminopyridine N-oxide, 61)
Show SMILES COCCNC(=O)c1ccc(c(C)c1)-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C23H21F2N3O4/c1-13-11-14(23(30)27-8-10-32-2)3-5-16(13)21-20(26)18(7-9-28(21)31)22(29)17-6-4-15(24)12-19(17)25/h3-7,9,11-12H,8,10,26H2,1-2H3,(H,27,30)
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n/an/a 70n/an/an/an/a7.525



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Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31627
PNG
(Aminopyridine N-oxide, 53)
Show SMILES Nc1c(cc[n+]([O-])c1-c1ccc(F)cc1F)C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C18H10F4N2O2/c19-9-1-3-11(14(21)7-9)17-16(23)13(5-6-24(17)26)18(25)12-4-2-10(20)8-15(12)22/h1-8H,23H2
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n/an/a 126n/an/an/an/a7.525



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Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31613
PNG
(Aminopyridine N-oxide, 39)
Show SMILES COc1ccccc1C(=O)c1cc[n+]([O-])c(c1N)-c1ccccc1Cl
Show InChI InChI=1S/C19H15ClN2O3/c1-25-16-9-5-3-7-13(16)19(23)14-10-11-22(24)18(17(14)21)12-6-2-4-8-15(12)20/h2-11H,21H2,1H3
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n/an/a 149n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31609
PNG
(Aminopyridine N-oxide, 35)
Show SMILES Nc1c(cc[n+]([O-])c1-c1ccccc1Cl)C(=O)c1ccccc1
Show InChI InChI=1S/C18H13ClN2O2/c19-15-9-5-4-8-13(15)17-16(20)14(10-11-21(17)23)18(22)12-6-2-1-3-7-12/h1-11H,20H2
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n/an/a 174n/an/an/an/a7.525



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Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31620
PNG
(Aminopyridine N-oxide, 46)
Show SMILES CC(C)c1ccccc1-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C21H18F2N2O2/c1-12(2)14-5-3-4-6-15(14)20-19(24)17(9-10-25(20)27)21(26)16-8-7-13(22)11-18(16)23/h3-12H,24H2,1-2H3
PDB
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n/an/a 208n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31616
PNG
(Aminopyridine N-oxide, 42)
Show SMILES Nc1c(cc[n+]([O-])c1-c1cccc(Cl)c1)C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C18H11ClF2N2O2/c19-11-3-1-2-10(8-11)17-16(22)14(6-7-23(17)25)18(24)13-5-4-12(20)9-15(13)21/h1-9H,22H2
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n/an/a 228n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31610
PNG
(Aminopyridine N-oxide, 36)
Show SMILES Cc1ccccc1-c1c(N)c(cc[n+]1[O-])C(=O)c1ccccc1
Show InChI InChI=1S/C19H16N2O2/c1-13-7-5-6-10-15(13)18-17(20)16(11-12-21(18)23)19(22)14-8-3-2-4-9-14/h2-12H,20H2,1H3
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n/an/a 411n/an/an/an/a7.525



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Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31631
PNG
(Aminopyridine N-oxide, 57)
Show SMILES Cc1cc(ccc1-c1c(N)c(cc[n+]1[O-])C(=O)c1ccc(F)cc1F)C(O)=O
Show InChI InChI=1S/C20H14F2N2O4/c1-10-8-11(20(26)27)2-4-13(10)18-17(23)15(6-7-24(18)28)19(25)14-5-3-12(21)9-16(14)22/h2-9H,23H2,1H3,(H,26,27)
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n/an/a 491n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31617
PNG
(Aminopyridine N-oxide, 43)
Show SMILES Nc1c(cc[n+]([O-])c1-c1ccc(Cl)cc1)C(=O)c1ccc(F)cc1F
Show InChI InChI=1S/C18H11ClF2N2O2/c19-11-3-1-10(2-4-11)17-16(22)14(7-8-23(17)25)18(24)13-6-5-12(20)9-15(13)21/h1-9H,22H2
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n/an/a 802n/an/an/an/a7.525



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Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31608
PNG
(Aminopyridine N-oxide, 34)
Show SMILES Nc1c(cc[n+]([O-])c1-c1ccccc1)C(=O)c1ccccc1
Show InChI InChI=1S/C18H14N2O2/c19-16-15(18(21)14-9-5-2-6-10-14)11-12-20(22)17(16)13-7-3-1-4-8-13/h1-12H,19H2
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n/an/a 967n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31614
PNG
(Aminopyridine N-oxide, 40)
Show SMILES Nc1c(cc[n+]([O-])c1-c1ccccc1Cl)C(=O)c1ccccc1C(F)(F)F
Show InChI InChI=1S/C19H12ClF3N2O2/c20-15-8-4-2-6-12(15)17-16(24)13(9-10-25(17)27)18(26)11-5-1-3-7-14(11)19(21,22)23/h1-10H,24H2
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n/an/a 1.66E+3n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM31611
PNG
(Aminopyridine N-oxide, 37)
Show SMILES Nc1c(cc[n+]([O-])c1-c1ccc(Cl)cc1)C(=O)c1ccccc1
Show InChI InChI=1S/C18H13ClN2O2/c19-14-8-6-12(7-9-14)17-16(20)15(10-11-21(17)23)18(22)13-4-2-1-3-5-13/h1-11H,20H2
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n/an/a 2.53E+3n/an/an/an/a7.525



Almirall Research Center



Assay Description
Enzymatic activity assay was performed in 96-well microtiter plates. Various concentrations of the test compound or vehicle controls were preincubate...


J Med Chem 52: 5531-45 (2009)


Article DOI: 10.1021/jm9008604
BindingDB Entry DOI: 10.7270/Q25719B5
More data for this
Ligand-Target Pair