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Compile Data Set for Download or QSAR

Found 27 hits from AmorePacific Corporation R&D Center   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM11639
PNG
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
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n/an/a 26.2n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422587
PNG
(CHEMBL423892)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=S)c1-c1ccc(F)cc1
Show InChI InChI=1S/C22H15FO3S2/c1-28(24,25)17-12-8-15(9-13-17)21-20(14-6-10-16(23)11-7-14)22(27)18-4-2-3-5-19(18)26-21/h2-13H,1H3
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n/an/a 73.1n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422584
PNG
(CHEMBL69026)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1ccccc1F
Show InChI InChI=1S/C22H15FO4S/c1-28(25,26)15-12-10-14(11-13-15)22-20(16-6-2-4-8-18(16)23)21(24)17-7-3-5-9-19(17)27-22/h2-13H,1H3
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n/an/a 76.1n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422578
PNG
(CHEMBL422623)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=S)c1-c1ccccc1
Show InChI InChI=1S/C22H16O3S2/c1-27(23,24)17-13-11-16(12-14-17)21-20(15-7-3-2-4-8-15)22(26)18-9-5-6-10-19(18)25-21/h2-14H,1H3
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n/an/a 101n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422570
PNG
(CHEMBL435189)
Show SMILES NS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1ccccc1
Show InChI InChI=1S/C21H15NO4S/c22-27(24,25)16-12-10-15(11-13-16)21-19(14-6-2-1-3-7-14)20(23)17-8-4-5-9-18(17)26-21/h1-13H,(H2,22,24,25)
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n/an/a 105n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422577
PNG
(CHEMBL133065)
Show SMILES NS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1ccc(F)cc1
Show InChI InChI=1S/C21H14FNO4S/c22-15-9-5-13(6-10-15)19-20(24)17-3-1-2-4-18(17)27-21(19)14-7-11-16(12-8-14)28(23,25)26/h1-12H,(H2,23,25,26)
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n/an/a 126n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422591
PNG
(CHEMBL133507)
Show SMILES COc1ccc(cc1)-c1c(oc2ccccc2c1=S)-c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C23H18O4S2/c1-26-17-11-7-15(8-12-17)21-22(16-9-13-18(14-10-16)29(2,24)25)27-20-6-4-3-5-19(20)23(21)28/h3-14H,1-2H3
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n/an/a 142n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422586
PNG
(CHEMBL132721)
Show SMILES NS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1ccccc1F
Show InChI InChI=1S/C21H14FNO4S/c22-17-7-3-1-5-15(17)19-20(24)16-6-2-4-8-18(16)27-21(19)13-9-11-14(12-10-13)28(23,25)26/h1-12H,(H2,23,25,26)
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n/an/a 177n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422590
PNG
(CHEMBL132190)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=S)c1-c1ccccc1F
Show InChI InChI=1S/C22H15FO3S2/c1-28(24,25)15-12-10-14(11-13-15)21-20(16-6-2-4-8-18(16)23)22(27)17-7-3-5-9-19(17)26-21/h2-13H,1H3
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n/an/a 194n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422589
PNG
(CHEMBL134512)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1ccc(F)cc1
Show InChI InChI=1S/C22H15FO4S/c1-28(25,26)17-12-8-15(9-13-17)22-20(14-6-10-16(23)11-7-14)21(24)18-4-2-3-5-19(18)27-22/h2-13H,1H3
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n/an/a 202n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422585
PNG
(CHEMBL134628)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C22H14Cl2O4S/c1-29(26,27)15-9-6-13(7-10-15)22-20(14-8-11-17(23)18(24)12-14)21(25)16-4-2-3-5-19(16)28-22/h2-12H,1H3
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n/an/a 269n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422571
PNG
(CHEMBL132562)
Show SMILES CSc1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C22H17NO4S2/c1-28-16-10-6-14(7-11-16)20-21(24)18-4-2-3-5-19(18)27-22(20)15-8-12-17(13-9-15)29(23,25)26/h2-13H,1H3,(H2,23,25,26)
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n/an/a 283n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422580
PNG
(CHEMBL334774)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1cc2ccccc2s1
Show InChI InChI=1S/C24H16O4S2/c1-30(26,27)17-12-10-15(11-13-17)24-22(21-14-16-6-2-5-9-20(16)29-21)23(25)18-7-3-4-8-19(18)28-24/h2-14H,1H3
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n/an/a 323n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422572
PNG
(CHEMBL336206)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1ccc(Cl)cc1
Show InChI InChI=1S/C22H15ClO4S/c1-28(25,26)17-12-8-15(9-13-17)22-20(14-6-10-16(23)11-7-14)21(24)18-4-2-3-5-19(18)27-22/h2-13H,1H3
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n/an/a 340n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422576
PNG
(CHEMBL134756)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C22H14Cl2O4S/c1-29(26,27)15-9-6-13(7-10-15)22-20(16-11-8-14(23)12-18(16)24)21(25)17-4-2-3-5-19(17)28-22/h2-12H,1H3
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n/an/a 359n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422592
PNG
(CHEMBL133421)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1cccc(Cl)c1
Show InChI InChI=1S/C22H15ClO4S/c1-28(25,26)17-11-9-14(10-12-17)22-20(15-5-4-6-16(23)13-15)21(24)18-7-2-3-8-19(18)27-22/h2-13H,1H3
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n/an/a 365n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422568
PNG
(CHEMBL335024)
Show SMILES COc1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C22H17NO5S/c1-27-16-10-6-14(7-11-16)20-21(24)18-4-2-3-5-19(18)28-22(20)15-8-12-17(13-9-15)29(23,25)26/h2-13H,1H3,(H2,23,25,26)
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n/an/a 392n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422574
PNG
(CHEMBL133787)
Show SMILES COc1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C23H18O5S/c1-27-17-11-7-15(8-12-17)21-22(24)19-5-3-4-6-20(19)28-23(21)16-9-13-18(14-10-16)29(2,25)26/h3-14H,1-2H3
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n/an/a 516n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422588
PNG
(CHEMBL133660)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=S)c1-c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C22H14Cl2O3S2/c1-29(25,26)15-9-6-13(7-10-15)21-20(14-8-11-17(23)18(24)12-14)22(28)16-4-2-3-5-19(16)27-21/h2-12H,1H3
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n/an/a 520n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422573
PNG
(CHEMBL132371)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1cccc(F)c1
Show InChI InChI=1S/C22H15FO4S/c1-28(25,26)17-11-9-14(10-12-17)22-20(15-5-4-6-16(23)13-15)21(24)18-7-2-3-8-19(18)27-22/h2-13H,1H3
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n/an/a 532n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422582
PNG
(CHEMBL334335)
Show SMILES NS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1ccc2OCOc2c1
Show InChI InChI=1S/C22H15NO6S/c23-30(25,26)15-8-5-13(6-9-15)22-20(14-7-10-18-19(11-14)28-12-27-18)21(24)16-3-1-2-4-17(16)29-22/h1-11H,12H2,(H2,23,25,26)
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n/an/a 925n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422575
PNG
(CHEMBL133659)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1ccccc1
Show InChI InChI=1S/C22H16O4S/c1-27(24,25)17-13-11-16(12-14-17)22-20(15-7-3-2-4-8-15)21(23)18-9-5-6-10-19(18)26-22/h2-14H,1H3
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n/an/a 929n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422581
PNG
(CHEMBL336354)
Show SMILES Cc1ccccc1-c1c(oc2ccccc2c1=O)-c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C23H18O4S/c1-15-7-3-4-8-18(15)21-22(24)19-9-5-6-10-20(19)27-23(21)16-11-13-17(14-12-16)28(2,25)26/h3-14H,1-2H3
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n/an/a 947n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422579
PNG
(CHEMBL307981)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccc(F)cc2c(=O)c1-c1cccnc1
Show InChI InChI=1S/C21H14FNO4S/c1-28(25,26)16-7-4-13(5-8-16)21-19(14-3-2-10-23-12-14)20(24)17-11-15(22)6-9-18(17)27-21/h2-12H,1H3
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n/an/a 1.26E+3n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422569
PNG
(CHEMBL72000)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1cccnc1
Show InChI InChI=1S/C21H15NO4S/c1-27(24,25)16-10-8-14(9-11-16)21-19(15-5-4-12-22-13-15)20(23)17-6-2-3-7-18(17)26-21/h2-13H,1H3
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n/an/a 1.32E+3n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422567
PNG
(CHEMBL334520)
Show SMILES COc1ccc(cn1)-c1c(oc2ccccc2c1=O)-c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C22H17NO5S/c1-27-19-12-9-15(13-23-19)20-21(24)17-5-3-4-6-18(17)28-22(20)14-7-10-16(11-8-14)29(2,25)26/h3-13H,1-2H3
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n/an/a 2.30E+3n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50422583
PNG
(CHEMBL134774)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1cccc2ccccc12
Show InChI InChI=1S/C26H18O4S/c1-31(28,29)19-15-13-18(14-16-19)26-24(25(27)22-10-4-5-12-23(22)30-26)21-11-6-8-17-7-2-3-9-20(17)21/h2-16H,1H3
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n/an/a 3.75E+3n/an/an/an/an/an/a



AmorePacific Corporation R&D Center

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against prostaglandin G/H synthase 2 using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 13: 413-7 (2003)


Article DOI: 10.1016/s0960-894x(02)00952-6
More data for this
Ligand-Target Pair