BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 8 hits from AmorePacific R&D Center   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50218963
PNG
(CHEMBL297626)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(Cl)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H17ClO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 26.5n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against prostaglandin G/H synthase 2 in mouse peritoneal macrophages


Bioorg Med Chem Lett 14: 1757-60 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.048
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50218964
PNG
(CHEMBL44223)
Show SMILES CC1(C)OC(=C(C1=O)c1cc(F)cc(F)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H16F2O4S/c1-19(2)18(22)16(12-8-13(20)10-14(21)9-12)17(25-19)11-4-6-15(7-5-11)26(3,23)24/h4-10H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 52.9n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against prostaglandin G/H synthase 2 in mouse peritoneal macrophages


Bioorg Med Chem Lett 14: 1757-60 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.048
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50224241
PNG
(CHEMBL298888)
Show SMILES C[S+]([O-])c1ccc(cc1)C1=C(C(=O)C(C)(C)O1)c1cccc(Cl)c1
Show InChI InChI=1S/C19H17ClO3S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(23-19)12-7-9-15(10-8-12)24(3)22/h4-11H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 831n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against prostaglandin G/H synthase 2 in mouse peritoneal macrophages


Bioorg Med Chem Lett 14: 1757-60 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.048
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus (Mouse))
BDBM50224242
PNG
(CHEMBL295497)
Show SMILES C[S+]([O-])c1ccc(cc1)C1=C(C(=O)C(C)(C)O1)c1cc(F)cc(F)c1
Show InChI InChI=1S/C19H16F2O3S/c1-19(2)18(22)16(12-8-13(20)10-14(21)9-12)17(24-19)11-4-6-15(7-5-11)25(3)23/h4-10H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.75E+3n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against prostaglandin G/H synthase 2 in mouse peritoneal macrophages


Bioorg Med Chem Lett 14: 1757-60 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.048
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218963
PNG
(CHEMBL297626)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(Cl)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H17ClO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.30E+3n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against prostaglandin G/H synthase 1 in mouse peritoneal macrophages


Bioorg Med Chem Lett 14: 1757-60 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.048
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218964
PNG
(CHEMBL44223)
Show SMILES CC1(C)OC(=C(C1=O)c1cc(F)cc(F)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H16F2O4S/c1-19(2)18(22)16(12-8-13(20)10-14(21)9-12)17(25-19)11-4-6-15(7-5-11)26(3,23)24/h4-10H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.32E+4n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against prostaglandin G/H synthase 1 in mouse peritoneal macrophages


Bioorg Med Chem Lett 14: 1757-60 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.048
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50224241
PNG
(CHEMBL298888)
Show SMILES C[S+]([O-])c1ccc(cc1)C1=C(C(=O)C(C)(C)O1)c1cccc(Cl)c1
Show InChI InChI=1S/C19H17ClO3S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(23-19)12-7-9-15(10-8-12)24(3)22/h4-11H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.38E+4n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against prostaglandin G/H synthase 1 in mouse peritoneal macrophages


Bioorg Med Chem Lett 14: 1757-60 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.048
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50224242
PNG
(CHEMBL295497)
Show SMILES C[S+]([O-])c1ccc(cc1)C1=C(C(=O)C(C)(C)O1)c1cc(F)cc(F)c1
Show InChI InChI=1S/C19H16F2O3S/c1-19(2)18(22)16(12-8-13(20)10-14(21)9-12)17(24-19)11-4-6-15(7-5-11)25(3)23/h4-10H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.75E+4n/an/an/an/an/an/a



AmorePacific R&D Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against prostaglandin G/H synthase 1 in mouse peritoneal macrophages


Bioorg Med Chem Lett 14: 1757-60 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.048
More data for this
Ligand-Target Pair