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Compile Data Set for Download or QSAR

Found 211 hits from Anhui Medical University   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50126186
PNG
(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Show SMILES C\C(=C/C(=O)Nc1ccccc1C(O)=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H17NO3/c1-14(16-11-10-15-6-2-3-7-17(15)13-16)12-20(23)22-19-9-5-4-8-18(19)21(24)25/h2-13H,1H3,(H,22,23)(H,24,25)/b14-12+
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n/an/a 93n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of human telomerase


Eur J Med Chem 112: 231-51 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50079528
PNG
(CHEMBL3417316)
Show SMILES CC1=C(O)C(=O)C=C2C1=CC=C1[C@@]2(C)CC[C@@]2(C)[C@@H]3C[C@@](C)(CC[C@]3(C)CC[C@]12C)C(=O)NCCO
Show InChI InChI=1S/C31H43NO4/c1-19-20-7-8-23-29(4,21(20)17-22(34)25(19)35)12-14-31(6)24-18-28(3,26(36)32-15-16-33)10-9-27(24,2)11-13-30(23,31)5/h7-8,17,24,33,35H,9-16,18H2,1-6H3,(H,32,36)/t24-,27-,28-,29+,30-,31+/m1/s1
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n/an/a 110n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 95: 166-73 (2015)


Article DOI: 10.1016/j.ejmech.2015.03.039
BindingDB Entry DOI: 10.7270/Q2W097NH
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM15581
PNG
(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C
Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3
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n/an/a 189n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-A expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50022026
PNG
(CHEMBL3297792)
Show SMILES O=C(SCc1ccco1)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C15H10O4S/c16-14-12(8-10-4-1-2-6-13(10)19-14)15(17)20-9-11-5-3-7-18-11/h1-8H,9H2
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n/an/a 210n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-B assessed as H2O2 production using p-tyramine substrate by fluorimetric method


Bioorg Med Chem 22: 3732-8 (2014)


Article DOI: 10.1016/j.bmc.2014.05.002
BindingDB Entry DOI: 10.7270/Q25B0425
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149979
PNG
(CHEMBL3770592)
Show SMILES CC1Oc2ccccc2C2CC(=NN2C1=O)c1ccc(F)cc1
Show InChI InChI=1S/C23H22BrN5O5S/c1-14(30)27-19(12-22(31)29-21-11-8-16(24)13-26-21)23(32)28-17-9-6-15(7-10-17)18-4-2-3-5-20(18)35(25,33)34/h2-11,13,19H,12H2,1H3,(H,27,30)(H,28,32)(H2,25,33,34)(H,26,29,31)
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n/an/a 221n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149968
PNG
(CHEMBL3770343)
Show SMILES Fc1ccc(cc1)C1=NN2C(C1)c1cc(Cl)ccc1OCC2=O
Show InChI InChI=1S/C30H34ClN5O3/c1-35(2)20-23-8-4-5-9-25(23)21-10-12-22(13-11-21)29(38)33-26(30(39)36-16-6-3-7-17-36)18-28(37)34-27-15-14-24(31)19-32-27/h4-5,8-15,19,26H,3,6-7,16-18,20H2,1-2H3,(H,33,38)(H,32,34,37)/t26-/m0/s1
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n/an/a 242n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50126186
PNG
(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Show SMILES C\C(=C/C(=O)Nc1ccccc1C(O)=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H17NO3/c1-14(16-11-10-15-6-2-3-7-17(15)13-16)12-20(23)22-19-9-5-4-8-18(19)21(24)25/h2-13H,1H3,(H,22,23)(H,24,25)/b14-12+
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n/an/a 280n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 74: 717-25 (2014)


Article DOI: 10.1016/j.ejmech.2013.06.014
BindingDB Entry DOI: 10.7270/Q21G0NRG
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50126186
PNG
(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Show SMILES C\C(=C/C(=O)Nc1ccccc1C(O)=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H17NO3/c1-14(16-11-10-15-6-2-3-7-17(15)13-16)12-20(23)22-19-9-5-4-8-18(19)21(24)25/h2-13H,1H3,(H,22,23)(H,24,25)/b14-12+
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n/an/a 280n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 90: 889-96 (2015)


Article DOI: 10.1016/j.ejmech.2014.12.013
BindingDB Entry DOI: 10.7270/Q29S1SP6
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM15579
PNG
(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C
Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1
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n/an/a 321n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50079529
PNG
(CHEMBL3417317)
Show SMILES CCC(O)NC(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CC=C5C(C)=C(O)C(=O)C=C5[C@]4(C)CC[C@@]3(C)[C@@H]2C1
Show InChI InChI=1S/C32H45NO4/c1-8-25(35)33-27(37)29(4)12-11-28(3)13-15-31(6)23-10-9-20-19(2)26(36)22(34)17-21(20)30(23,5)14-16-32(31,7)24(28)18-29/h9-10,17,24-25,35-36H,8,11-16,18H2,1-7H3,(H,33,37)/t24-,25?,28-,29-,30+,31-,32+/m1/s1
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n/an/a 340n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 95: 166-73 (2015)


Article DOI: 10.1016/j.ejmech.2015.03.039
BindingDB Entry DOI: 10.7270/Q2W097NH
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149970
PNG
(CHEMBL3769793)
Show SMILES CC1Oc2ccccc2C2CC(=NN2C1=O)c1ccccc1Cl
Show InChI InChI=1S/C26H26BrN5O7S/c1-2-39-24(34)15-30-26(36)20(13-23(33)32-22-12-11-18(27)14-29-22)31-25(35)17-9-7-16(8-10-17)19-5-3-4-6-21(19)40(28,37)38/h3-12,14,20H,2,13,15H2,1H3,(H,30,36)(H,31,35)(H2,28,37,38)(H,29,32,33)
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n/an/a 348n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50126186
PNG
(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Show SMILES C\C(=C/C(=O)Nc1ccccc1C(O)=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C21H17NO3/c1-14(16-11-10-15-6-2-3-7-17(15)13-16)12-20(23)22-19-9-5-4-8-18(19)21(24)25/h2-13H,1H3,(H,22,23)(H,24,25)/b14-12+
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n/an/a 410n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 95: 166-73 (2015)


Article DOI: 10.1016/j.ejmech.2015.03.039
BindingDB Entry DOI: 10.7270/Q2W097NH
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149978
PNG
(CHEMBL3770032)
Show SMILES CC1Oc2ccccc2C2CC(=NN2C1=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C23H23BrN6O5S/c24-15-7-10-20(27-13-15)30-21(31)11-18(29-22(32)12-25)23(33)28-16-8-5-14(6-9-16)17-3-1-2-4-19(17)36(26,34)35/h1-10,13,18H,11-12,25H2,(H,28,33)(H,29,32)(H2,26,34,35)(H,27,30,31)
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n/an/a 452n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149969
PNG
(CHEMBL3769971)
Show SMILES COc1ccc(cc1)C1=NN2C(C1)c1cc(Br)cc(Br)c1OCC2=O
Show InChI InChI=1S/C24H24BrN5O5S/c1-2-22(31)29-19(13-23(32)30-21-12-9-16(25)14-27-21)24(33)28-17-10-7-15(8-11-17)18-5-3-4-6-20(18)36(26,34)35/h3-12,14,19H,2,13H2,1H3,(H,28,33)(H,29,31)(H2,26,34,35)(H,27,30,32)
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n/an/a 467n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50446421
PNG
(CHEMBL3109740)
Show SMILES C\C(=C/C(=O)Nc1ccc(cc1C(O)=O)N1CCOCC1)c1ccc2ccccc2c1
Show InChI InChI=1S/C25H24N2O4/c1-17(19-7-6-18-4-2-3-5-20(18)15-19)14-24(28)26-23-9-8-21(16-22(23)25(29)30)27-10-12-31-13-11-27/h2-9,14-16H,10-13H2,1H3,(H,26,28)(H,29,30)/b17-14+
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n/an/a 470n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of human telomerase


Eur J Med Chem 112: 231-51 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149967
PNG
(CHEMBL3771168)
Show SMILES Clc1ccc(cc1)C1=NN2C(C1)c1cc(Cl)ccc1OCC2=O
Show InChI InChI=1S/C24H29ClN6O3/c1-30(2)22(26)16-6-8-17(9-7-16)23(33)28-19(24(34)31-12-4-3-5-13-31)14-21(32)29-20-11-10-18(25)15-27-20/h6-11,15,19,26H,3-5,12-14H2,1-2H3,(H,28,33)(H,27,29,32)/t19-/m0/s1
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n/an/a 504n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149975
PNG
(CHEMBL3770982)
Show SMILES Fc1ccccc1C1=NN2C(C1)c1cc(Cl)ccc1OCC2=O
Show InChI InChI=1S/C32H36BrN5O3/c33-26-14-15-29(34-21-26)36-30(39)20-28(32(41)38-18-4-1-5-19-38)35-31(40)24-12-10-23(11-13-24)27-9-3-2-8-25(27)22-37-16-6-7-17-37/h2-3,8-15,21,28H,1,4-7,16-20,22H2,(H,35,40)(H,34,36,39)/t28-/m0/s1
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n/an/a 584n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50071058
PNG
((2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,1...)
Show SMILES C[C@]12CC[C@](C)(C[C@H]1[C@]1(C)CC[C@]3(C)C(=CC=c4c3cc(O)c(O)c4=C)[C@@]1(C)CC2)C(O)=O
Show InChI InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,30-31H,1,9-14,16H2,2-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
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n/an/a 780n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 95: 166-73 (2015)


Article DOI: 10.1016/j.ejmech.2015.03.039
BindingDB Entry DOI: 10.7270/Q2W097NH
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50446919
PNG
(CHEMBL3115514)
Show SMILES CCCCSCC(=O)N1N=C(C[C@@H]1c1ccc(cc1)C(F)(F)F)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C25H23F3N2O3S/c1-2-3-12-34-15-23(31)30-21(16-8-10-18(11-9-16)25(26,27)28)14-20(29-30)19-13-17-6-4-5-7-22(17)33-24(19)32/h4-11,13,21H,2-3,12,14-15H2,1H3/t21-/m1/s1
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n/an/a 920n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 74: 717-25 (2014)


Article DOI: 10.1016/j.ejmech.2013.06.014
BindingDB Entry DOI: 10.7270/Q21G0NRG
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM29158
PNG
(3-carboxamido coumarin, 8)
Show SMILES Cc1cccc(NC(=O)c2cc3ccccc3oc2=O)c1
Show InChI InChI=1S/C17H13NO3/c1-11-5-4-7-13(9-11)18-16(19)14-10-12-6-2-3-8-15(12)21-17(14)20/h2-10H,1H3,(H,18,19)
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n/an/a 930n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-B expressed in baculovirus infected insect cell microsomes assessed as p-tyramine conversion to resorufin and H2O...


Eur J Med Chem 80: 278-84 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.060
BindingDB Entry DOI: 10.7270/Q2S46TJH
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50160391
PNG
(CHEMBL3786231)
Show SMILES CCCCN(CCCC)CC(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C28H33N3O3/c1-3-5-16-30(17-6-4-2)20-27(32)31-25(21-12-8-7-9-13-21)19-24(29-31)23-18-22-14-10-11-15-26(22)34-28(23)33/h7-15,18,25H,3-6,16-17,19-20H2,1-2H3
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n/an/a 980n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay


Eur J Med Chem 112: 231-51 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50062612
PNG
(CHEMBL3397662)
Show SMILES CCCc1nn(C)c(C(N)=O)c1NC(=O)\C=C\c1ccco1
Show InChI InChI=1S/C15H18N4O3/c1-3-5-11-13(14(15(16)21)19(2)18-11)17-12(20)8-7-10-6-4-9-22-10/h4,6-9H,3,5H2,1-2H3,(H2,16,21)(H,17,20)/b8-7+
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n/an/a 1.02E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 90: 889-96 (2015)


Article DOI: 10.1016/j.ejmech.2014.12.013
BindingDB Entry DOI: 10.7270/Q29S1SP6
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50446917
PNG
(CHEMBL3115522)
Show SMILES CCCSCC(=O)N1N=C(C)C[C@@H]1c1cc(Br)cc(Br)c1O
Show InChI InChI=1S/C15H18Br2N2O2S/c1-3-4-22-8-14(20)19-13(5-9(2)18-19)11-6-10(16)7-12(17)15(11)21/h6-7,13,21H,3-5,8H2,1-2H3/t13-/m1/s1
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n/an/a 1.04E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 74: 717-25 (2014)


Article DOI: 10.1016/j.ejmech.2013.06.014
BindingDB Entry DOI: 10.7270/Q21G0NRG
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50446915
PNG
(CHEMBL3115524)
Show SMILES COC(=O)CSCC(=O)N1N=C(C)C[C@@H]1c1cc(Br)cc(Br)c1O
Show InChI InChI=1S/C15H16Br2N2O4S/c1-8-3-12(10-4-9(16)5-11(17)15(10)22)19(18-8)13(20)6-24-7-14(21)23-2/h4-5,12,22H,3,6-7H2,1-2H3/t12-/m1/s1
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PubMed
n/an/a 1.19E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 74: 717-25 (2014)


Article DOI: 10.1016/j.ejmech.2013.06.014
BindingDB Entry DOI: 10.7270/Q21G0NRG
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50160320
PNG
(CHEMBL3786261)
Show SMILES CC(=O)Oc1ccccc1C1CC(C)=NN1C(=O)CCl
Show InChI InChI=1S/C14H15ClN2O3/c1-9-7-12(17(16-9)14(19)8-15)11-5-3-4-6-13(11)20-10(2)18/h3-6,12H,7-8H2,1-2H3
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n/an/a 1.27E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay


Eur J Med Chem 112: 231-51 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149965
PNG
(CHEMBL3771008)
Show SMILES Clc1ccccc1C1=NN2C(C1)c1ccccc1OCC2=O
Show InChI InChI=1S/C24H29ClN6O3/c1-30(2)22(26)16-6-8-17(9-7-16)23(33)28-19(24(34)31-12-4-3-5-13-31)14-21(32)29-20-11-10-18(25)15-27-20/h6-11,15,19,26H,3-5,12-14H2,1-2H3,(H,28,33)(H,27,29,32)/t19-/m1/s1
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n/an/a 1.32E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50079533
PNG
(CHEMBL3417322)
Show SMILES CN(C)CCN1CCN(CC1)C(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CC=C5C(C)=C(O)C(=O)C=C5[C@]4(C)CC[C@@]3(C)[C@@H]2C1
Show InChI InChI=1S/C37H55N3O3/c1-25-26-9-10-29-35(4,27(26)23-28(41)31(25)42)14-16-37(6)30-24-34(3,12-11-33(30,2)13-15-36(29,37)5)32(43)40-21-19-39(20-22-40)18-17-38(7)8/h9-10,23,30,42H,11-22,24H2,1-8H3/t30-,33-,34-,35+,36-,37+/m1/s1
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n/an/a 1.41E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 95: 166-73 (2015)


Article DOI: 10.1016/j.ejmech.2015.03.039
BindingDB Entry DOI: 10.7270/Q2W097NH
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149966
PNG
(CHEMBL3770839)
Show SMILES Cc1ccc(cc1)C1=NN2C(C1)c1cc(Cl)ccc1OCC2=O
Show InChI InChI=1S/C32H36ClN5O4/c33-26-12-13-29(34-21-26)36-30(39)20-28(32(41)38-14-4-1-5-15-38)35-31(40)24-10-8-23(9-11-24)27-7-3-2-6-25(27)22-37-16-18-42-19-17-37/h2-3,6-13,21,28H,1,4-5,14-20,22H2,(H,35,40)(H,34,36,39)/t28-/m0/s1
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n/an/a 1.63E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149972
PNG
(CHEMBL3770481)
Show SMILES Fc1ccc(cc1)C1=NN2C(C1)c1ccccc1OCC2=O
Show InChI InChI=1S/C22H20BrN3O4S/c23-17-9-11-18(12-10-17)26-21(27)13-14-25-22(28)16-7-5-15(6-8-16)19-3-1-2-4-20(19)31(24,29)30/h1-12H,13-14H2,(H,25,28)(H,26,27)(H2,24,29,30)
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PubMed
n/an/a 1.78E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50062608
PNG
(CHEMBL3397658)
Show SMILES CCCc1nn(C)c(C(N)=O)c1NC(=O)\C=C\c1ccccc1
Show InChI InChI=1S/C17H20N4O2/c1-3-7-13-15(16(17(18)23)21(2)20-13)19-14(22)11-10-12-8-5-4-6-9-12/h4-6,8-11H,3,7H2,1-2H3,(H2,18,23)(H,19,22)/b11-10+
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PubMed
n/an/a 1.98E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 90: 889-96 (2015)


Article DOI: 10.1016/j.ejmech.2014.12.013
BindingDB Entry DOI: 10.7270/Q29S1SP6
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50379997
PNG
(CHEMBL2012477)
Show SMILES CC1CCN(CC(=O)N2N=C(CC2c2ccccc2)c2cc3ccccc3oc2=O)CC1
Show InChI InChI=1S/C26H27N3O3/c1-18-11-13-28(14-12-18)17-25(30)29-23(19-7-3-2-4-8-19)16-22(27-29)21-15-20-9-5-6-10-24(20)32-26(21)31/h2-10,15,18,23H,11-14,16-17H2,1H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase supercoiling activity in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA assay


Eur J Med Chem 51: 294-9 (2012)


Article DOI: 10.1016/j.ejmech.2012.02.040
BindingDB Entry DOI: 10.7270/Q28053M9
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50446921
PNG
(CHEMBL3115509)
Show SMILES CCCCSCC(=O)N1N=C(C[C@@H]1c1ccccc1C(F)(F)F)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C25H23F3N2O3S/c1-2-3-12-34-15-23(31)30-21(17-9-5-6-10-19(17)25(26,27)28)14-20(29-30)18-13-16-8-4-7-11-22(16)33-24(18)32/h4-11,13,21H,2-3,12,14-15H2,1H3/t21-/m1/s1
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n/an/a 2.00E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 74: 717-25 (2014)


Article DOI: 10.1016/j.ejmech.2013.06.014
BindingDB Entry DOI: 10.7270/Q21G0NRG
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50060593
PNG
(CHEMBL3394522)
Show SMILES CC1=NN(C(C1)c1cc(Br)cc(Br)c1O)C(=O)CN1CCNCC1
Show InChI InChI=1S/C16H20Br2N4O2/c1-10-6-14(12-7-11(17)8-13(18)16(12)24)22(20-10)15(23)9-21-4-2-19-3-5-21/h7-8,14,19,24H,2-6,9H2,1H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A using p-tyramine as substrate assessed as production of H2O2 incubated for 15 mins prior to substrate addition ...


Bioorg Med Chem 23: 515-25 (2015)


Article DOI: 10.1016/j.bmc.2014.12.010
BindingDB Entry DOI: 10.7270/Q2R2132N
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50079532
PNG
(CHEMBL3417321)
Show SMILES CC1=C(O)C(=O)C=C2C1=CC=C1[C@@]2(C)CC[C@@]2(C)[C@@H]3C[C@@](C)(CC[C@]3(C)CC[C@]12C)C(=O)N1CCN(CCO)CC1
Show InChI InChI=1S/C35H50N2O4/c1-23-24-7-8-27-33(4,25(24)21-26(39)29(23)40)12-14-35(6)28-22-32(3,10-9-31(28,2)11-13-34(27,35)5)30(41)37-17-15-36(16-18-37)19-20-38/h7-8,21,28,38,40H,9-20,22H2,1-6H3/t28-,31-,32-,33+,34-,35+/m1/s1
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n/an/a 2.01E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 95: 166-73 (2015)


Article DOI: 10.1016/j.ejmech.2015.03.039
BindingDB Entry DOI: 10.7270/Q2W097NH
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50105463
PNG
(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Show SMILES CCn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12
Show InChI InChI=1S/C21H19N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,23H,2,22H2,1H3/p+1
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n/an/a 2.10E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cell extracts after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 74: 717-25 (2014)


Article DOI: 10.1016/j.ejmech.2013.06.014
BindingDB Entry DOI: 10.7270/Q21G0NRG
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50105463
PNG
(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Show SMILES CCn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12
Show InChI InChI=1S/C21H19N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,23H,2,22H2,1H3/p+1
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n/an/a 2.10E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA


Eur J Med Chem 90: 889-96 (2015)


Article DOI: 10.1016/j.ejmech.2014.12.013
BindingDB Entry DOI: 10.7270/Q29S1SP6
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50160330
PNG
(CHEMBL3785281)
Show SMILES CN1CCN(CC(=O)N2N=C(C)CC2c2ccccc2O)CC1
Show InChI InChI=1S/C17H24N4O2/c1-13-11-15(14-5-3-4-6-16(14)22)21(18-13)17(23)12-20-9-7-19(2)8-10-20/h3-6,15,22H,7-12H2,1-2H3
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n/an/a 2.10E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay


Eur J Med Chem 112: 231-51 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50160326
PNG
(CHEMBL3787380)
Show SMILES CC(=O)Oc1ccccc1C1CC(C)=NN1C(=O)CN1CCCCC1
Show InChI InChI=1S/C19H25N3O3/c1-14-12-17(16-8-4-5-9-18(16)25-15(2)23)22(20-14)19(24)13-21-10-6-3-7-11-21/h4-5,8-9,17H,3,6-7,10-13H2,1-2H3
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n/an/a 2.12E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay


Eur J Med Chem 112: 231-51 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50149963
PNG
(CHEMBL3770527)
Show SMILES O=C1COc2ccccc2C2CC(=NN12)c1ccccc1
Show InChI InChI=1S/C24H21ClN4O4S/c25-18-9-10-20-17(13-18)14-21(29-20)24(31)28-12-11-27-23(30)16-7-5-15(6-8-16)19-3-1-2-4-22(19)34(26,32)33/h1-10,13-14,29H,11-12H2,(H,27,30)(H,28,31)(H2,26,32,33)
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n/an/a 2.20E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-A expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50160312
PNG
(CHEMBL3786734)
Show SMILES ClCC(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C20H15ClN2O3/c21-12-19(24)23-17(13-6-2-1-3-7-13)11-16(22-23)15-10-14-8-4-5-9-18(14)26-20(15)25/h1-10,17H,11-12H2
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n/an/a 2.27E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay


Eur J Med Chem 112: 231-51 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50060579
PNG
(CHEMBL3394516)
Show SMILES Oc1ccc(Cl)cc1C1CC(=NN1C(=O)CN1CCNCC1)c1ccc(F)cc1
Show InChI InChI=1S/C21H22ClFN4O2/c22-15-3-6-20(28)17(11-15)19-12-18(14-1-4-16(23)5-2-14)25-27(19)21(29)13-26-9-7-24-8-10-26/h1-6,11,19,24,28H,7-10,12-13H2
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n/an/a 2.40E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A using p-tyramine as substrate assessed as production of H2O2 incubated for 15 mins prior to substrate addition ...


Bioorg Med Chem 23: 515-25 (2015)


Article DOI: 10.1016/j.bmc.2014.12.010
BindingDB Entry DOI: 10.7270/Q2R2132N
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50105463
PNG
(2,7-diamino-10-ethyl-9-phenylphenanthridinium brom...)
Show SMILES CCn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12
Show InChI InChI=1S/C21H19N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,23H,2,22H2,1H3/p+1
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n/an/a 2.47E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase supercoiling activity in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA assay


Eur J Med Chem 51: 294-9 (2012)


Article DOI: 10.1016/j.ejmech.2012.02.040
BindingDB Entry DOI: 10.7270/Q28053M9
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149974
PNG
(CHEMBL3769823)
Show SMILES Clc1ccc2OCC(=O)N3N=C(CC3c2c1)c1ccccc1
Show InChI InChI=1S/C22H20BrN3O4S/c23-18-11-9-17(10-12-18)22(28)26-14-13-25-21(27)16-7-5-15(6-8-16)19-3-1-2-4-20(19)31(24,29)30/h1-12H,13-14H2,(H,25,27)(H,26,28)(H2,24,29,30)
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n/an/a 2.57E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149973
PNG
(CHEMBL3770540)
Show SMILES COc1ccc(cc1)C1=NN2C(C1)c1cc(Cl)ccc1OCC2=O
Show InChI InChI=1S/C32H36ClN5O3/c33-26-14-15-29(34-21-26)36-30(39)20-28(32(41)38-18-4-1-5-19-38)35-31(40)24-12-10-23(11-13-24)27-9-3-2-8-25(27)22-37-16-6-7-17-37/h2-3,8-15,21,28H,1,4-7,16-20,22H2,(H,35,40)(H,34,36,39)/t28-/m0/s1
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n/an/a 2.72E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM15581
PNG
(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C
Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3
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n/an/a 2.76E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A using p-tyramine as substrate assessed as production of H2O2 incubated for 15 mins prior to substrate addition ...


Bioorg Med Chem 23: 515-25 (2015)


Article DOI: 10.1016/j.bmc.2014.12.010
BindingDB Entry DOI: 10.7270/Q2R2132N
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM15579
PNG
(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C
Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1
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n/an/a 2.82E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-B using p-tyramine as substrate assessed as production of H2O2 incubated for 15 mins prior to substrate addition ...


Bioorg Med Chem 23: 515-25 (2015)


Article DOI: 10.1016/j.bmc.2014.12.010
BindingDB Entry DOI: 10.7270/Q2R2132N
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50149963
PNG
(CHEMBL3770527)
Show SMILES O=C1COc2ccccc2C2CC(=NN12)c1ccccc1
Show InChI InChI=1S/C24H21ClN4O4S/c25-18-9-10-20-17(13-18)14-21(29-20)24(31)28-12-11-27-23(30)16-7-5-15(6-8-16)19-3-1-2-4-22(19)34(26,32)33/h1-10,13-14,29H,11-12H2,(H,27,30)(H,28,31)(H2,26,32,33)
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n/an/a 2.88E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human microsomal MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate assessed as H2O2 produc...


Bioorg Med Chem 24: 1741-8 (2016)


Article DOI: 10.1016/j.bmc.2016.02.045
BindingDB Entry DOI: 10.7270/Q2T72K99
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))
BDBM50016105
PNG
(CHEMBL3261198)
Show SMILES Cc1ccccc1NC(=O)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C17H13NO3/c1-11-6-2-4-8-14(11)18-16(19)13-10-12-7-3-5-9-15(12)21-17(13)20/h2-10H,1H3,(H,18,19)
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n/an/a 2.96E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-B expressed in baculovirus infected insect cell microsomes assessed as p-tyramine conversion to resorufin and H2O...


Eur J Med Chem 80: 278-84 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.060
BindingDB Entry DOI: 10.7270/Q2S46TJH
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50160384
PNG
(CHEMBL3786296)
Show SMILES FC(F)(F)c1ccccc1C1CC(=NN1C(=O)CN1CCOCC1)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C25H22F3N3O4/c26-25(27,28)19-7-3-2-6-17(19)21-14-20(18-13-16-5-1-4-8-22(16)35-24(18)33)29-31(21)23(32)15-30-9-11-34-12-10-30/h1-8,13,21H,9-12,14-15H2
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n/an/a 3.03E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay


Eur J Med Chem 112: 231-51 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50160396
PNG
(CHEMBL3787509)
Show SMILES CNCC(=O)N1N=C(CC1c1ccccc1)c1cc2ccccc2oc1=O
Show InChI InChI=1S/C21H19N3O3/c1-22-13-20(25)24-18(14-7-3-2-4-8-14)12-17(23-24)16-11-15-9-5-6-10-19(15)27-21(16)26/h2-11,18,22H,12-13H2,1H3
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n/an/a 3.15E+3n/an/an/an/an/an/a



Anhui Medical University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human MGC-803 cells after 24 hrs by TRAP-PCR-ELISA assay


Eur J Med Chem 112: 231-51 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.009
BindingDB Entry DOI: 10.7270/Q2SB47N4
More data for this
Ligand-Target Pair
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