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Compile Data Set for Download or QSAR

Found 3 hits from Arena Pharmaceuticals, Inc   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50307811
PNG
(1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)phenyl)-3-(...)
Show SMILES Cn1ncc(Br)c1-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C17H14BrClN4O/c1-23-16(15(18)10-20-23)11-3-2-4-14(9-11)22-17(24)21-13-7-5-12(19)6-8-13/h2-10H,1H3,(H2,21,22,24)
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 19n/an/an/an/a



Arena Pharmaceuticals, Inc

Curated by ChEMBL


Assay Description
Activity at human 5HT2A receptor expressed in HEK293 cells assessed as [3H]inositol phosphate production by scintillation counting


J Med Chem 53: 1923-36 (2010)


Article DOI: 10.1021/jm9007328
BindingDB Entry DOI: 10.7270/Q24B31FP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50307813
PNG
(1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)phenyl)-3-(...)
Show SMILES Cn1ncc(Br)c1-c1cccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)c1
Show InChI InChI=1S/C18H14BrF3N4O2/c1-26-16(15(19)10-23-26)11-3-2-4-13(9-11)25-17(27)24-12-5-7-14(8-6-12)28-18(20,21)22/h2-10H,1H3,(H2,24,25,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 120n/an/an/an/a



Arena Pharmaceuticals, Inc

Curated by ChEMBL


Assay Description
Activity at human 5HT2A receptor expressed in HEK293 cells assessed as [3H]inositol phosphate production by scintillation counting


J Med Chem 53: 1923-36 (2010)


Article DOI: 10.1021/jm9007328
BindingDB Entry DOI: 10.7270/Q24B31FP
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50307812
PNG
(1-[3-(4-Bromo-2-methyl-2Hpyrazol-3-yl)-4-methoxyph...)
Show SMILES COc1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1-c1c(Br)cnn1C
Show InChI InChI=1S/C18H16BrClN4O2/c1-24-17(15(19)10-21-24)14-9-13(7-8-16(14)26-2)23-18(25)22-12-5-3-11(20)4-6-12/h3-10H,1-2H3,(H2,22,23,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 0.700n/an/an/an/a



Arena Pharmaceuticals, Inc

Curated by ChEMBL


Assay Description
Activity at human 5HT2A receptor expressed in HEK293 cells assessed as [3H]inositol phosphate production by scintillation counting


J Med Chem 53: 1923-36 (2010)


Article DOI: 10.1021/jm9007328
BindingDB Entry DOI: 10.7270/Q24B31FP
More data for this
Ligand-Target Pair