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Compile Data Set for Download or QSAR

Found 3 hits from Astra Charnwood   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Cavia porcellus)
BDBM50408719
PNG
(CHEMBL107779)
Show SMILES CCN(CC)CCOc1ccccc1C(=O)Cc1ccccc1
Show InChI InChI=1S/C20H25NO2/c1-3-21(4-2)14-15-23-20-13-9-8-12-18(20)19(22)16-17-10-6-5-7-11-17/h5-13H,3-4,14-16H2,1-2H3
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PubMed
n/an/an/a 214n/an/an/an/an/a



Astra Charnwood

Curated by ChEMBL


Assay Description
The compound was tested for antagonistic activity against Muscarinic acetylcholine receptor M3 in guinea pig trachea


J Med Chem 42: 3210-6 (1999)


Article DOI: 10.1021/jm980409n
BindingDB Entry DOI: 10.7270/Q2P84D4V
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Cavia porcellus)
BDBM50408721
PNG
(CHEMBL323050)
Show SMILES CCCOc1ccccc1C(=O)NC1CCCCC1CN1CCCCC1
Show InChI InChI=1S/C22H34N2O2/c1-2-16-26-21-13-7-5-11-19(21)22(25)23-20-12-6-4-10-18(20)17-24-14-8-3-9-15-24/h5,7,11,13,18,20H,2-4,6,8-10,12,14-17H2,1H3,(H,23,25)
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Similars

Article
PubMed
n/an/an/a 1.48E+4n/an/an/an/an/a



Astra Charnwood

Curated by ChEMBL


Assay Description
The compound was tested for antagonistic activity against Muscarinic acetylcholine receptor M3 in guinea pig trachea


J Med Chem 42: 3210-6 (1999)


Article DOI: 10.1021/jm980409n
BindingDB Entry DOI: 10.7270/Q2P84D4V
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Cavia porcellus)
BDBM50408720
PNG
(CHEMBL109489)
Show SMILES O=C(Nc1ccccc1)OC1CCCCC1CN1CCOCC1
Show InChI InChI=1S/C18H26N2O3/c21-18(19-16-7-2-1-3-8-16)23-17-9-5-4-6-15(17)14-20-10-12-22-13-11-20/h1-3,7-8,15,17H,4-6,9-14H2,(H,19,21)
MMDB

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CHEMBL
PC cid
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PubMed
n/an/an/a 2.88E+3n/an/an/an/an/a



Astra Charnwood

Curated by ChEMBL


Assay Description
The compound was tested for antagonistic activity against Muscarinic acetylcholine receptor M3 in guinea pig trachea


J Med Chem 42: 3210-6 (1999)


Article DOI: 10.1021/jm980409n
BindingDB Entry DOI: 10.7270/Q2P84D4V
More data for this
Ligand-Target Pair