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Compile Data Set for Download or QSAR

Found 1019 hits from Bayer Research Center   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin K


(Homo sapiens (human))
BDBM19807
PNG
(CHEMBL100563 | benzyl N-[(1S)-1-({1-[(2S)-2-{[(ben...)
Show SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NC1CN(CC1=O)C(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C32H42N4O7/c1-21(2)15-25(34-31(40)42-19-23-11-7-5-8-12-23)29(38)33-27-17-36(18-28(27)37)30(39)26(16-22(3)4)35-32(41)43-20-24-13-9-6-10-14-24/h5-14,21-22,25-27H,15-20H2,1-4H3,(H,33,38)(H,34,40)(H,35,41)/t25-,26-,27?/m0/s1
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2n/an/an/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against Cathepsin K


Bioorg Med Chem Lett 11: 2951-4 (2001)


Article DOI: 10.1016/s0960-894x(01)00600-x
BindingDB Entry DOI: 10.7270/Q23R0S5W
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Cathepsin (H and K)


(Homo sapiens (human))
BDBM50106075
PNG
((S)-1-[2-Oxo-2-(3,4,5-trimethoxy-phenyl)-ethyl]-pi...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCCN1CC(=O)c1cc(OC)c(OC)c(OC)c1)\C=C\c1ccccc1
Show InChI InChI=1S/C30H40N2O5/c1-6-21(2)24(16-15-22-12-8-7-9-13-22)31-30(34)25-14-10-11-17-32(25)20-26(33)23-18-27(35-3)29(37-5)28(19-23)36-4/h7-9,12-13,15-16,18-19,21,24-25H,6,10-11,14,17,20H2,1-5H3,(H,31,34)/b16-15+/t21-,24+,25-/m0/s1
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790n/an/an/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against cathepsin K


Bioorg Med Chem Lett 11: 2951-4 (2001)


Article DOI: 10.1016/s0960-894x(01)00600-x
BindingDB Entry DOI: 10.7270/Q23R0S5W
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 1


(Homo sapiens (human))
BDBM50164702
PNG
(4-[4-(3H-Benzoimidazol-5-ylamino)-5-trifluoromethy...)
Show SMILES NS(=O)(=O)c1ccc(Nc2ncc(c(Nc3ccc4nc[nH]c4c3)n2)C(F)(F)F)cc1
Show InChI InChI=1S/C18H14F3N7O2S/c19-18(20,21)13-8-23-17(27-10-1-4-12(5-2-10)31(22,29)30)28-16(13)26-11-3-6-14-15(7-11)25-9-24-14/h1-9H,(H,24,25)(H2,22,29,30)(H2,23,26,27,28)
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n/an/a 0.100n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against Cyclin dependent kinase 1


Bioorg Med Chem Lett 15: 1973-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.076
BindingDB Entry DOI: 10.7270/Q2610ZT5
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147315
PNG
(2-(4-(3-fluorophenyl)piperidine-1-carbonyl)-4-(2-m...)
Show SMILES COCCc1c(C)n(oc1=O)C(=O)N1CCC(CC1)c1cccc(F)c1
Show InChI InChI=1S/C19H23FN2O4/c1-13-17(8-11-25-2)18(23)26-22(13)19(24)21-9-6-14(7-10-21)15-4-3-5-16(20)12-15/h3-5,12,14H,6-11H2,1-2H3
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n/an/a 0.200n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 1


(Homo sapiens (human))
BDBM50164693
PNG
(CHEMBL194721 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Show SMILES FC(F)(F)c1cnc(Nc2ccc3nc[nH]c3c2)nc1Nc1ccccc1Cl
Show InChI InChI=1S/C18H12ClF3N6/c19-12-3-1-2-4-13(12)27-16-11(18(20,21)22)8-23-17(28-16)26-10-5-6-14-15(7-10)25-9-24-14/h1-9H,(H,24,25)(H2,23,26,27,28)
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n/an/a 0.900n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against Cyclin dependent kinase 1


Bioorg Med Chem Lett 15: 1973-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.076
BindingDB Entry DOI: 10.7270/Q2610ZT5
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Homo sapiens (Human))
BDBM50147297
PNG
(4-Isopropyl-2-[4-(3-methoxy-phenyl)-piperazine-1-c...)
Show SMILES COc1cccc(c1)N1CCN(CC1)C(=O)n1oc(=O)c(C(C)C)c1C
Show InChI InChI=1S/C19H25N3O4/c1-13(2)17-14(3)22(26-18(17)23)19(24)21-10-8-20(9-11-21)15-6-5-7-16(12-15)25-4/h5-7,12-13H,8-11H2,1-4H3
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n/an/a 1n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147299
PNG
(4-Butyl-3-methyl-2-(4-methyl-piperidine-1-carbonyl...)
Show SMILES CCCCc1c(C)n(oc1=O)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C15H24N2O3/c1-4-5-6-13-12(3)17(20-14(13)18)15(19)16-9-7-11(2)8-10-16/h11H,4-10H2,1-3H3
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Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50215791
PNG
(2-((2-acetamidopyridin-4-yl)methylamino)-N-(2,2-di...)
Show SMILES CC(=O)Nc1cc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1
Show InChI InChI=1S/C22H18F2N4O4/c1-13(29)27-20-10-14(8-9-25-20)12-26-17-5-3-2-4-16(17)21(30)28-15-6-7-18-19(11-15)32-22(23,24)31-18/h2-11,26H,12H2,1H3,(H,28,30)(H,25,27,29)
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n/an/a 1n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cKit by FRET assay


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50215758
PNG
(2-((2-aminopyridin-4-yl)methylamino)-N-(2,2-difluo...)
Show SMILES Nc1cc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1
Show InChI InChI=1S/C20H16F2N4O3/c21-20(22)28-16-6-5-13(10-17(16)29-20)26-19(27)14-3-1-2-4-15(14)25-11-12-7-8-24-18(23)9-12/h1-10,25H,11H2,(H2,23,24)(H,26,27)
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n/an/a 1n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cKit by FRET assay


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Homo sapiens (Human))
BDBM50147251
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1cccs1
Show InChI InChI=1S/C14H18N2O3S/c1-9(2)12-10(3)16(19-13(12)17)14(18)15(4)8-11-6-5-7-20-11/h5-7,9H,8H2,1-4H3
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n/an/a 2n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (human))
BDBM50091927
PNG
(1-(2,6-Dichloro-phenyl)-1-(4'-fluoro-6-hydroxymeth...)
Show SMILES Cc1cc(F)ccc1-c1cc(ccc1CO)N(C(N)=O)c1c(Cl)cccc1Cl
Show InChI InChI=1S/C21H17Cl2FN2O2/c1-12-9-14(24)6-8-16(12)17-10-15(7-5-13(17)11-27)26(21(25)28)20-18(22)3-2-4-19(20)23/h2-10,27H,11H2,1H3,(H2,25,28)
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n/an/a 2n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory activity against Mitogen-activated protein kinase p38 alpha 2 expressed in E. coli.


Bioorg Med Chem Lett 10: 2047-50 (2000)


Article DOI: 10.1016/s0960-894x(00)00270-5
BindingDB Entry DOI: 10.7270/Q2FB526H
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Homo sapiens (Human))
BDBM50147270
PNG
(3-Methyl-4-(2-phenoxy-ethyl)-2-(piperidine-1-carbo...)
Show SMILES Cc1c(CCOc2ccccc2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C18H22N2O4/c1-14-16(10-13-23-15-8-4-2-5-9-15)17(21)24-20(14)18(22)19-11-6-3-7-12-19/h2,4-5,8-9H,3,6-7,10-13H2,1H3
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n/an/a 2n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147243
PNG
(4-Isopropyl-3-methyl-2-(piperidine-1-carbonyl)-2H-...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCCCC1
Show InChI InChI=1S/C13H20N2O3/c1-9(2)11-10(3)15(18-12(11)16)13(17)14-7-5-4-6-8-14/h9H,4-8H2,1-3H3
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Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Estrogen receptor


(RAT)
BDBM17292
PNG
((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Show SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2O
Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
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n/an/a 2n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Binding to Estrogen receptor- alpha (ER alpha) receptor


Bioorg Med Chem Lett 12: 2875-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00613-3
BindingDB Entry DOI: 10.7270/Q2F18Z2H
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cyclin-dependent kinase 1


(Homo sapiens (human))
BDBM50164726
PNG
((3H-Benzoimidazol-5-yl)-(4-isobutoxy-5-trifluorome...)
Show SMILES CC(C)COc1nc(Nc2ccc3nc[nH]c3c2)ncc1C(F)(F)F
Show InChI InChI=1S/C16H16F3N5O/c1-9(2)7-25-14-11(16(17,18)19)6-20-15(24-14)23-10-3-4-12-13(5-10)22-8-21-12/h3-6,8-9H,7H2,1-2H3,(H,21,22)(H,20,23,24)
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n/an/a 2n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against Cyclin dependent kinase 1


Bioorg Med Chem Lett 15: 1973-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.076
BindingDB Entry DOI: 10.7270/Q2610ZT5
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50215766
PNG
(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Show SMILES NC(=O)c1cc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1
Show InChI InChI=1S/C21H16F2N4O4/c22-21(23)30-17-6-5-13(10-18(17)31-21)27-20(29)14-3-1-2-4-15(14)26-11-12-7-8-25-16(9-12)19(24)28/h1-10,26H,11H2,(H2,24,28)(H,27,29)
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Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cKit by FRET assay


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Estrogen receptor


(Rattus norvegicus)
BDBM17292
PNG
((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Show SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2O
Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
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Bayer Research Center

Curated by ChEMBL


Assay Description
Binding to Estrogen receptor- beta (ER beta) receptor


Bioorg Med Chem Lett 12: 2875-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00613-3
BindingDB Entry DOI: 10.7270/Q2F18Z2H
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Hormone-sensitive lipase (HSL)


(Homo sapiens (Human))
BDBM50138735
PNG
((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCC[C@H](C)C1
Show InChI InChI=1S/C14H22N2O3/c1-9(2)12-11(4)16(19-13(12)17)14(18)15-7-5-6-10(3)8-15/h9-10H,5-8H2,1-4H3/t10-/m0/s1
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n/an/a 3n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50215793
PNG
(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Show SMILES CNC(=O)c1cc(CNc2ccsc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1
Show InChI InChI=1S/C20H16F2N4O4S/c1-23-18(27)14-8-11(4-6-24-14)10-25-13-5-7-31-17(13)19(28)26-12-2-3-15-16(9-12)30-20(21,22)29-15/h2-9,25H,10H2,1H3,(H,23,27)(H,26,28)
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Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cKit by FRET assay


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 1


(Homo sapiens (human))
BDBM50164724
PNG
(CHEMBL193922 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Show SMILES FC(F)(F)c1cnc(Nc2ccc3nc[nH]c3c2)nc1Nc1cccc(Cl)c1
Show InChI InChI=1S/C18H12ClF3N6/c19-10-2-1-3-11(6-10)26-16-13(18(20,21)22)8-23-17(28-16)27-12-4-5-14-15(7-12)25-9-24-14/h1-9H,(H,24,25)(H2,23,26,27,28)
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n/an/a 3n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against Cyclin dependent kinase 1


Bioorg Med Chem Lett 15: 1973-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.076
BindingDB Entry DOI: 10.7270/Q2610ZT5
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM50215761
PNG
(1-(5-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Show SMILES CNC(=O)Nc1ccc(CNc2ncsc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)cn1
Show InChI InChI=1S/C19H16F2N6O4S/c1-22-18(29)27-14-5-2-10(7-23-14)8-24-16-15(32-9-25-16)17(28)26-11-3-4-12-13(6-11)31-19(20,21)30-12/h2-7,9,24H,8H2,1H3,(H,26,28)(H2,22,23,27,29)
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n/an/a 3n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147251
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1cccs1
Show InChI InChI=1S/C14H18N2O3S/c1-9(2)12-10(3)16(19-13(12)17)14(18)15(4)8-11-6-5-7-20-11/h5-7,9H,8H2,1-4H3
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n/an/a 3n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50215774
PNG
(CHEMBL246424 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Show SMILES CNc1nccc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)n1
Show InChI InChI=1S/C20H17F2N5O3/c1-23-19-24-9-8-13(27-19)11-25-15-5-3-2-4-14(15)18(28)26-12-6-7-16-17(10-12)30-20(21,22)29-16/h2-10,25H,11H2,1H3,(H,26,28)(H,23,24,27)
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n/an/a 3n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cKit by FRET assay


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147281
PNG
(4-Isobutyl-3-methyl-2-(4-methyl-piperidine-1-carbo...)
Show SMILES CC(C)Cc1c(C)n(oc1=O)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C15H24N2O3/c1-10(2)9-13-12(4)17(20-14(13)18)15(19)16-7-5-11(3)6-8-16/h10-11H,5-9H2,1-4H3
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n/an/a 3n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147257
PNG
(4-(2-Ethoxy-ethyl)-3-methyl-2-(4-methyl-piperidine...)
Show SMILES CCOCCc1c(C)n(oc1=O)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C15H24N2O4/c1-4-20-10-7-13-12(3)17(21-14(13)18)15(19)16-8-5-11(2)6-9-16/h11H,4-10H2,1-3H3
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n/an/a 3n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50215788
PNG
(CHEMBL399534 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Show SMILES CNc1cc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1
Show InChI InChI=1S/C21H18F2N4O3/c1-24-19-10-13(8-9-25-19)12-26-16-5-3-2-4-15(16)20(28)27-14-6-7-17-18(11-14)30-21(22,23)29-17/h2-11,26H,12H2,1H3,(H,24,25)(H,27,28)
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n/an/a 3n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cKit by FRET assay


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Homo sapiens (Human))
BDBM50147253
PNG
(2-(4-(3-fluorophenyl)piperidine-1-carbonyl)-4-isop...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCC(CC1)c1cccc(F)c1
Show InChI InChI=1S/C19H23FN2O3/c1-12(2)17-13(3)22(25-18(17)23)19(24)21-9-7-14(8-10-21)15-5-4-6-16(20)11-15/h4-6,11-12,14H,7-10H2,1-3H3
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n/an/a 4n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Homo sapiens (Human))
BDBM50147279
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1ccccc1F
Show InChI InChI=1S/C16H19FN2O3/c1-10(2)14-11(3)19(22-15(14)20)16(21)18(4)9-12-7-5-6-8-13(12)17/h5-8,10H,9H2,1-4H3
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n/an/a 4n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 1


(Homo sapiens (human))
BDBM50164706
PNG
((3H-Benzoimidazol-5-yl)-(4-o-tolyloxy-5-trifluorom...)
Show SMILES Cc1ccccc1Oc1nc(Nc2ccc3nc[nH]c3c2)ncc1C(F)(F)F
Show InChI InChI=1S/C19H14F3N5O/c1-11-4-2-3-5-16(11)28-17-13(19(20,21)22)9-23-18(27-17)26-12-6-7-14-15(8-12)25-10-24-14/h2-10H,1H3,(H,24,25)(H,23,26,27)
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n/an/a 4n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against Cyclin dependent kinase 1


Bioorg Med Chem Lett 15: 1973-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.076
BindingDB Entry DOI: 10.7270/Q2610ZT5
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 1


(Homo sapiens (human))
BDBM50164711
PNG
(CHEMBL195423 | N*2*-(3H-Benzoimidazol-5-yl)-5-brom...)
Show SMILES Fc1ccc(Nc2nc(Nc3ccc4nc[nH]c4c3)ncc2Br)cc1
Show InChI InChI=1S/C17H12BrFN6/c18-13-8-20-17(24-12-5-6-14-15(7-12)22-9-21-14)25-16(13)23-11-3-1-10(19)2-4-11/h1-9H,(H,21,22)(H2,20,23,24,25)
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n/an/a 4n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against Cyclin dependent kinase 1


Bioorg Med Chem Lett 15: 1973-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.076
BindingDB Entry DOI: 10.7270/Q2610ZT5
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Homo sapiens (Human))
BDBM50147245
PNG
(4-Isobutyl-3-methyl-2-(4-phenyl-piperidine-1-carbo...)
Show SMILES CC(C)Cc1c(C)n(oc1=O)C(=O)N1CCC(CC1)c1ccccc1
Show InChI InChI=1S/C20H26N2O3/c1-14(2)13-18-15(3)22(25-19(18)23)20(24)21-11-9-17(10-12-21)16-7-5-4-6-8-16/h4-8,14,17H,9-13H2,1-3H3
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n/an/a 4n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 1


(Homo sapiens (human))
BDBM50164725
PNG
(CHEMBL193367 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Show SMILES FC(F)(F)c1cnc(Nc2ccc3nc[nH]c3c2)nc1Nc1ccc(Cl)cc1
Show InChI InChI=1S/C18H12ClF3N6/c19-10-1-3-11(4-2-10)26-16-13(18(20,21)22)8-23-17(28-16)27-12-5-6-14-15(7-12)25-9-24-14/h1-9H,(H,24,25)(H2,23,26,27,28)
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n/an/a 4n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibitory concentration against Cyclin dependent kinase 1


Bioorg Med Chem Lett 15: 1973-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.02.076
BindingDB Entry DOI: 10.7270/Q2610ZT5
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50215770
PNG
(1-(5-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Show SMILES CCNC(=O)Nc1ccc(CNc2ncsc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)cn1
Show InChI InChI=1S/C20H18F2N6O4S/c1-2-23-19(30)28-15-6-3-11(8-24-15)9-25-17-16(33-10-26-17)18(29)27-12-4-5-13-14(7-12)32-20(21,22)31-13/h3-8,10,25H,2,9H2,1H3,(H,27,29)(H2,23,24,28,30)
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n/an/a 4n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cKit by FRET assay


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50215759
PNG
(CHEMBL247423 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Show SMILES OCCOCCNc1cc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1
Show InChI InChI=1S/C24H24F2N4O5/c25-24(26)34-20-6-5-17(14-21(20)35-24)30-23(32)18-3-1-2-4-19(18)29-15-16-7-8-27-22(13-16)28-9-11-33-12-10-31/h1-8,13-14,29,31H,9-12,15H2,(H,27,28)(H,30,32)
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Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cKit by FRET assay


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50215758
PNG
(2-((2-aminopyridin-4-yl)methylamino)-N-(2,2-difluo...)
Show SMILES Nc1cc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1
Show InChI InChI=1S/C20H16F2N4O3/c21-20(22)28-16-6-5-13(10-17(16)29-20)26-19(27)14-3-1-2-4-15(14)25-11-12-7-8-24-18(23)9-12/h1-10,25H,11H2,(H2,23,24)(H,26,27)
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n/an/a 4n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cKit by FRET assay


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147241
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1ccco1
Show InChI InChI=1S/C14H18N2O4/c1-9(2)12-10(3)16(20-13(12)17)14(18)15(4)8-11-6-5-7-19-11/h5-7,9H,8H2,1-4H3
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Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147267
PNG
(4-Cyclohexyl-3-methyl-2-(4-methyl-piperidine-1-car...)
Show SMILES CC1CCN(CC1)C(=O)n1oc(=O)c(C2CCCCC2)c1C
Show InChI InChI=1S/C17H26N2O3/c1-12-8-10-18(11-9-12)17(21)19-13(2)15(16(20)22-19)14-6-4-3-5-7-14/h12,14H,3-11H2,1-2H3
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Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147272
PNG
(4-(2-Methoxy-ethyl)-3-methyl-2-(4-m-tolyl-piperidi...)
Show SMILES COCCc1c(C)n(oc1=O)C(=O)N1CCC(CC1)c1cccc(C)c1
Show InChI InChI=1S/C20H26N2O4/c1-14-5-4-6-17(13-14)16-7-10-21(11-8-16)20(24)22-15(2)18(9-12-25-3)19(23)26-22/h4-6,13,16H,7-12H2,1-3H3
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Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147270
PNG
(3-Methyl-4-(2-phenoxy-ethyl)-2-(piperidine-1-carbo...)
Show SMILES Cc1c(CCOc2ccccc2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C18H22N2O4/c1-14-16(10-13-23-15-8-4-2-5-9-15)17(21)24-20(14)18(22)19-11-6-3-7-12-19/h2,4-5,8-9H,3,6-7,10-13H2,1H3
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Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Epidermal growth factor receptor and ErbB2 (HER1 and HER2)


(Homo sapiens (human))
BDBM50114250
PNG
(1-(5-tert-Butyl-2-methyl-2H-pyrazol-3-yl)-3-(4-pyr...)
Show SMILES Cn1nc(cc1NC(=O)Nc1ccc(Cc2ccncc2)cc1)C(C)(C)C
Show InChI InChI=1S/C21H25N5O/c1-21(2,3)18-14-19(26(4)25-18)24-20(27)23-17-7-5-15(6-8-17)13-16-9-11-22-12-10-16/h5-12,14H,13H2,1-4H3,(H2,23,24,27)
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n/an/a 4.20n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human epidermal growth factor receptor-2


Bioorg Med Chem Lett 12: 1559-62 (2002)


Article DOI: 10.1016/s0960-894x(02)00238-x
BindingDB Entry DOI: 10.7270/Q2CV4H28
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Homo sapiens (Human))
BDBM50147298
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1cccc(F)c1
Show InChI InChI=1S/C16H19FN2O3/c1-10(2)14-11(3)19(22-15(14)20)16(21)18(4)9-12-6-5-7-13(17)8-12/h5-8,10H,9H2,1-4H3
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PubMed
n/an/a 5n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Homo sapiens (Human))
BDBM50147248
PNG
(4-(2-Methoxy-ethyl)-3-methyl-2-(4-phenyl-piperidin...)
Show SMILES COCCc1c(C)n(oc1=O)C(=O)N1CCC(CC1)c1ccccc1
Show InChI InChI=1S/C19H24N2O4/c1-14-17(10-13-24-2)18(22)25-21(14)19(23)20-11-8-16(9-12-20)15-6-4-3-5-7-15/h3-7,16H,8-13H2,1-2H3
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n/an/a 5n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
RAF serine/threonine protein kinase


(Homo sapiens (human))
BDBM50215791
PNG
(2-((2-acetamidopyridin-4-yl)methylamino)-N-(2,2-di...)
Show SMILES CC(=O)Nc1cc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1
Show InChI InChI=1S/C22H18F2N4O4/c1-13(29)27-20-10-14(8-9-25-20)12-26-17-5-3-2-4-16(17)21(30)28-15-6-7-18-19(11-15)32-22(23,24)31-18/h2-11,26H,12H2,1H3,(H,28,30)(H,25,27,29)
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PubMed
n/an/a 5n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of b-Raf


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50215761
PNG
(1-(5-((5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Show SMILES CNC(=O)Nc1ccc(CNc2ncsc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)cn1
Show InChI InChI=1S/C19H16F2N6O4S/c1-22-18(29)27-14-5-2-10(7-23-14)8-24-16-15(32-9-25-16)17(28)26-11-3-4-12-13(6-11)31-19(20,21)30-12/h2-7,9,24H,8H2,1H3,(H,26,28)(H2,22,23,27,29)
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n/an/a 5n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cKit by FRET assay


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50215773
PNG
(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)carba...)
Show SMILES CNC(=O)c1cc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1
Show InChI InChI=1S/C22H18F2N4O4/c1-25-21(30)17-10-13(8-9-26-17)12-27-16-5-3-2-4-15(16)20(29)28-14-6-7-18-19(11-14)32-22(23,24)31-18/h2-11,27H,12H2,1H3,(H,25,30)(H,28,29)
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n/an/a 5n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cKit by FRET assay


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147303
PNG
(4-Benzyl-3-methyl-2-(piperidine-1-carbonyl)-2H-iso...)
Show SMILES Cc1c(Cc2ccccc2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C17H20N2O3/c1-13-15(12-14-8-4-2-5-9-14)16(20)22-19(13)17(21)18-10-6-3-7-11-18/h2,4-5,8-9H,3,6-7,10-12H2,1H3
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n/an/a 5n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147289
PNG
(4-Isobutyl-3-methyl-2-(piperidine-1-carbonyl)-2H-i...)
Show SMILES CC(C)Cc1c(C)n(oc1=O)C(=O)N1CCCCC1
Show InChI InChI=1S/C14H22N2O3/c1-10(2)9-12-11(3)16(19-13(12)17)14(18)15-7-5-4-6-8-15/h10H,4-9H2,1-3H3
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PubMed
n/an/a 5n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Hormone sensitive lipase


(Homo sapiens (Human))
BDBM50147260
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1ccccc1
Show InChI InChI=1S/C16H20N2O3/c1-11(2)14-12(3)18(21-15(14)19)16(20)17(4)10-13-8-6-5-7-9-13/h5-9,11H,10H2,1-4H3
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n/an/a 5n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cells


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50215775
PNG
(1-(4-((2-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)ca...)
Show SMILES CNC(=O)Nc1cc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1
Show InChI InChI=1S/C22H19F2N5O4/c1-25-21(31)29-19-10-13(8-9-26-19)12-27-16-5-3-2-4-15(16)20(30)28-14-6-7-17-18(11-14)33-22(23,24)32-17/h2-11,27H,12H2,1H3,(H,28,30)(H2,25,26,29,31)
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PubMed
n/an/a 5n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cKit by FRET assay


Bioorg Med Chem Lett 17: 4378-81 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.075
BindingDB Entry DOI: 10.7270/Q28K78S7
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Homo sapiens (Human))
BDBM50147276
PNG
(4-Cyclopentyl-3-methyl-2-(piperidine-1-carbonyl)-2...)
Show SMILES Cc1c(C2CCCC2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C15H22N2O3/c1-11-13(12-7-3-4-8-12)14(18)20-17(11)15(19)16-9-5-2-6-10-16/h12H,2-10H2,1H3
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PubMed
n/an/a 6n/an/an/an/an/an/a



Bayer Research Center

Curated by ChEMBL


Assay Description
Inhibition of human recombinant hormone sensitive lipase (HSL)


Bioorg Med Chem Lett 14: 3155-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.015
BindingDB Entry DOI: 10.7270/Q2NV9HQ5
More data for this
Ligand-Target Pair
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