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Compile Data Set for Download or QSAR

Found 160 hits from Biographics Laboratory 3R   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162384
PNG
(CHEMBL194283 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES COc1ccc(cc1)C(CNCCc1cc(C)cc(C)c1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C29H43N3O/c1-23-19-24(2)21-25(20-23)13-14-30-22-29(26-9-11-28(33-3)12-10-26)32-17-15-31(16-18-32)27-7-5-4-6-8-27/h9-12,19-21,27,29-30H,4-8,13-18,22H2,1-3H3
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50n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162418
PNG
(CHEMBL195671 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES COc1ccc(cc1)C(CNCCc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C27H37Cl2N3O/c1-33-26-9-7-22(8-10-26)27(20-30-12-11-21-17-23(28)19-24(29)18-21)32-15-13-31(14-16-32)25-5-3-2-4-6-25/h7-10,17-19,25,27,30H,2-6,11-16,20H2,1H3
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62n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162346
PNG
(CHEMBL365551 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES Clc1cc(Cl)cc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccccc2)c1
Show InChI InChI=1S/C26H35Cl2N3/c27-23-17-21(18-24(28)19-23)11-12-29-20-26(22-7-3-1-4-8-22)31-15-13-30(14-16-31)25-9-5-2-6-10-25/h1,3-4,7-8,17-19,25-26,29H,2,5-6,9-16,20H2
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80n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162366
PNG
(CHEMBL193850 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES COc1ccccc1CCNCC(N1CCN(CC1)C1CCCCC1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C28H38F3N3O/c1-35-27-10-6-5-7-23(27)15-16-32-21-26(22-11-13-24(14-12-22)28(29,30)31)34-19-17-33(18-20-34)25-8-3-2-4-9-25/h5-7,10-14,25-26,32H,2-4,8-9,15-21H2,1H3
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118n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162361
PNG
(CHEMBL193507 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES FC(F)(F)c1ccc(cc1)C(CNCCc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C27H34Cl2F3N3/c28-23-16-20(17-24(29)18-23)10-11-33-19-26(21-6-8-22(9-7-21)27(30,31)32)35-14-12-34(13-15-35)25-4-2-1-3-5-25/h6-9,16-18,25-26,33H,1-5,10-15,19H2
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129n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162424
PNG
(1-{2-[4-(3,4-Dichloro-phenyl)-piperazin-1-yl]-4-me...)
Show SMILES CC(C)CC(CNC(=O)Nc1ccc(C)cc1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C24H32Cl2N4O/c1-17(2)14-21(16-27-24(31)28-19-6-4-18(3)5-7-19)30-12-10-29(11-13-30)20-8-9-22(25)23(26)15-20/h4-9,15,17,21H,10-14,16H2,1-3H3,(H2,27,28,31)
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179n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162376
PNG
(CHEMBL195480 | [2-(4-tert-Butyl-phenyl)-2-(4-cyclo...)
Show SMILES COc1ccccc1CCNCC(N1CCN(CC1)C1CCCCC1)c1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C31H47N3O/c1-31(2,3)27-16-14-25(15-17-27)29(24-32-19-18-26-10-8-9-13-30(26)35-4)34-22-20-33(21-23-34)28-11-6-5-7-12-28/h8-10,13-17,28-29,32H,5-7,11-12,18-24H2,1-4H3
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216n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162373
PNG
(CHEMBL193938 | [2-(4-tert-Butyl-phenyl)-2-(4-cyclo...)
Show SMILES CC(C)(C)c1ccc(cc1)C(CNCCc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C30H43Cl2N3/c1-30(2,3)25-11-9-24(10-12-25)29(22-33-14-13-23-19-26(31)21-27(32)20-23)35-17-15-34(16-18-35)28-7-5-4-6-8-28/h9-12,19-21,28-29,33H,4-8,13-18,22H2,1-3H3
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224n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162357
PNG
(CHEMBL195293 | [2-(4-tert-Butyl-phenyl)-2-(4-cyclo...)
Show SMILES CC(C)(C)c1ccc(cc1)C(CNCCc1ccc(cc1)C(F)(F)F)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C31H44F3N3/c1-30(2,3)26-15-11-25(12-16-26)29(37-21-19-36(20-22-37)28-7-5-4-6-8-28)23-35-18-17-24-9-13-27(14-10-24)31(32,33)34/h9-16,28-29,35H,4-8,17-23H2,1-3H3
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231n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162372
PNG
(1-[2-(4-Cyclohexyl-piperazin-1-yl)-4-methyl-pentyl...)
Show SMILES CC(C)CC(CNC(=O)Nc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C23H36Cl2N4O/c1-17(2)12-22(16-26-23(30)27-20-14-18(24)13-19(25)15-20)29-10-8-28(9-11-29)21-6-4-3-5-7-21/h13-15,17,21-22H,3-12,16H2,1-2H3,(H2,26,27,30)
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296n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162386
PNG
((4-{2-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-pip...)
Show SMILES CN(C)c1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(C)(C)C)cc1
Show InChI InChI=1S/C32H50N4/c1-32(2,3)28-15-13-27(14-16-28)31(25-33-20-19-26-11-17-29(18-12-26)34(4)5)36-23-21-35(22-24-36)30-9-7-6-8-10-30/h11-18,30-31,33H,6-10,19-25H2,1-5H3
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312n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162405
PNG
(1-{2-[4-(3,4-Dichloro-phenyl)-piperazin-1-yl]-4-me...)
Show SMILES CC(C)CC(CNC(=O)Nc1cc(C)cc(C)c1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C25H34Cl2N4O/c1-17(2)11-22(16-28-25(32)29-20-13-18(3)12-19(4)14-20)31-9-7-30(8-10-31)21-5-6-23(26)24(27)15-21/h5-6,12-15,17,22H,7-11,16H2,1-4H3,(H2,28,29,32)
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313n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162412
PNG
(1-[2-Biphenyl-4-yl-2-(4-cyclohexyl-piperazin-1-yl)...)
Show SMILES Cc1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)-c2ccccc2)cc1
Show InChI InChI=1S/C32H40N4O/c1-25-12-18-29(19-13-25)34-32(37)33-24-31(28-16-14-27(15-17-28)26-8-4-2-5-9-26)36-22-20-35(21-23-36)30-10-6-3-7-11-30/h2,4-5,8-9,12-19,30-31H,3,6-7,10-11,20-24H2,1H3,(H2,33,34,37)
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316n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162356
PNG
(1-[2-Biphenyl-4-yl-2-(4-cyclohexyl-piperazin-1-yl)...)
Show SMILES Cc1cc(C)cc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)-c2ccccc2)c1
Show InChI InChI=1S/C33H42N4O/c1-25-21-26(2)23-30(22-25)35-33(38)34-24-32(29-15-13-28(14-16-29)27-9-5-3-6-10-27)37-19-17-36(18-20-37)31-11-7-4-8-12-31/h3,5-6,9-10,13-16,21-23,31-32H,4,7-8,11-12,17-20,24H2,1-2H3,(H2,34,35,38)
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326n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162432
PNG
(CHEMBL364047 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES COc1ccccc1C(CNCCc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C27H37Cl2N3O/c1-33-27-10-6-5-9-25(27)26(20-30-12-11-21-17-22(28)19-23(29)18-21)32-15-13-31(14-16-32)24-7-3-2-4-8-24/h5-6,9-10,17-19,24,26,30H,2-4,7-8,11-16,20H2,1H3
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344n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162411
PNG
(CHEMBL194161 | [2-(4-tert-Butyl-phenyl)-2-(4-cyclo...)
Show SMILES COc1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(C)(C)C)cc1
Show InChI InChI=1S/C31H47N3O/c1-31(2,3)27-14-12-26(13-15-27)30(24-32-19-18-25-10-16-29(35-4)17-11-25)34-22-20-33(21-23-34)28-8-6-5-7-9-28/h10-17,28,30,32H,5-9,18-24H2,1-4H3
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346n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162349
PNG
(CHEMBL193973 | [2-(4-tert-Butyl-phenyl)-2-(4-cyclo...)
Show SMILES CC(C)(C)c1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(C)(C)C)cc1
Show InChI InChI=1S/C34H53N3/c1-33(2,3)29-16-12-27(13-17-29)20-21-35-26-32(28-14-18-30(19-15-28)34(4,5)6)37-24-22-36(23-25-37)31-10-8-7-9-11-31/h12-19,31-32,35H,7-11,20-26H2,1-6H3
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349n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162425
PNG
(CHEMBL365596 | [2-(4-tert-Butyl-phenyl)-2-(4-cyclo...)
Show SMILES CC(C)(C)c1ccc(cc1)C(CNCCc1ccccc1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C30H45N3/c1-30(2,3)27-16-14-26(15-17-27)29(24-31-19-18-25-10-6-4-7-11-25)33-22-20-32(21-23-33)28-12-8-5-9-13-28/h4,6-7,10-11,14-17,28-29,31H,5,8-9,12-13,18-24H2,1-3H3
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350n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162413
PNG
(CHEMBL427357 | [2-(4-Methoxy-phenyl)-ethyl]-[2-(4-...)
Show SMILES COc1ccc(CCNCC(N2CCN(CC2)c2ccccc2)c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C28H32F3N3O/c1-35-26-13-7-22(8-14-26)15-16-32-21-27(23-9-11-24(12-10-23)28(29,30)31)34-19-17-33(18-20-34)25-5-3-2-4-6-25/h2-14,27,32H,15-21H2,1H3
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393n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162394
PNG
(1-(4-Chloro-phenyl)-3-[2-(4-cyclohexyl-piperazin-1...)
Show SMILES CC(C)CC(CNC(=O)Nc1ccc(Cl)cc1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C23H37ClN4O/c1-18(2)16-22(17-25-23(29)26-20-10-8-19(24)9-11-20)28-14-12-27(13-15-28)21-6-4-3-5-7-21/h8-11,18,21-22H,3-7,12-17H2,1-2H3,(H2,25,26,29)
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429n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162371
PNG
(CHEMBL194435 | Dimethyl-{4-[1-(4-phenyl-piperazin-...)
Show SMILES CN(C)c1ccc(cc1)C(CNCCc1ccc(C)cc1)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C29H38N4/c1-24-9-11-25(12-10-24)17-18-30-23-29(26-13-15-27(16-14-26)31(2)3)33-21-19-32(20-22-33)28-7-5-4-6-8-28/h4-16,29-30H,17-23H2,1-3H3
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435n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162408
PNG
(CHEMBL365806 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES COc1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C28H38F3N3O/c1-35-26-13-7-22(8-14-26)15-16-32-21-27(23-9-11-24(12-10-23)28(29,30)31)34-19-17-33(18-20-34)25-5-3-2-4-6-25/h7-14,25,27,32H,2-6,15-21H2,1H3
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477n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162410
PNG
(1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluorom...)
Show SMILES FC(F)(F)c1ccc(cc1)C(CNC(=O)Nc1ccccc1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C26H33F3N4O/c27-26(28,29)21-13-11-20(12-14-21)24(19-30-25(34)31-22-7-3-1-4-8-22)33-17-15-32(16-18-33)23-9-5-2-6-10-23/h1,3-4,7-8,11-14,23-24H,2,5-6,9-10,15-19H2,(H2,30,31,34)
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479n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162367
PNG
(CHEMBL194135 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES FC(F)(F)c1ccc(cc1)C(CNCCc1ccccc1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C27H36F3N3/c28-27(29,30)24-13-11-23(12-14-24)26(21-31-16-15-22-7-3-1-4-8-22)33-19-17-32(18-20-33)25-9-5-2-6-10-25/h1,3-4,7-8,11-14,25-26,31H,2,5-6,9-10,15-21H2
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484n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162407
PNG
(CHEMBL195657 | [2-(4-tert-Butyl-phenyl)-2-(4-pheny...)
Show SMILES COc1ccccc1CCNCC(N1CCN(CC1)c1ccccc1)c1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C31H41N3O/c1-31(2,3)27-16-14-25(15-17-27)29(24-32-19-18-26-10-8-9-13-30(26)35-4)34-22-20-33(21-23-34)28-11-6-5-7-12-28/h5-17,29,32H,18-24H2,1-4H3
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488n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162369
PNG
(CHEMBL195081 | [2-Biphenyl-4-yl-2-(4-cyclohexyl-pi...)
Show SMILES Cc1cc(C)cc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)-c2ccccc2)c1
Show InChI InChI=1S/C34H45N3/c1-27-23-28(2)25-29(24-27)17-18-35-26-34(32-15-13-31(14-16-32)30-9-5-3-6-10-30)37-21-19-36(20-22-37)33-11-7-4-8-12-33/h3,5-6,9-10,13-16,23-25,33-35H,4,7-8,11-12,17-22,26H2,1-2H3
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517n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162398
PNG
(CHEMBL193828 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES Cc1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C28H38F3N3/c1-22-7-9-23(10-8-22)15-16-32-21-27(24-11-13-25(14-12-24)28(29,30)31)34-19-17-33(18-20-34)26-5-3-2-4-6-26/h7-14,26-27,32H,2-6,15-21H2,1H3
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545n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162379
PNG
(CHEMBL195406 | [2-(4-Methoxy-phenyl)-2-(4-phenyl-p...)
Show SMILES COc1ccc(cc1)C(CNCCc1ccc(C)cc1)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C28H35N3O/c1-23-8-10-24(11-9-23)16-17-29-22-28(25-12-14-27(32-2)15-13-25)31-20-18-30(19-21-31)26-6-4-3-5-7-26/h3-15,28-29H,16-22H2,1-2H3
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597n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162393
PNG
(CHEMBL193535 | Dimethyl-(4-{2-[2-(4-phenyl-piperaz...)
Show SMILES CN(C)c1ccc(CCNCC(N2CCN(CC2)c2ccccc2)c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C29H35F3N4/c1-34(2)26-14-8-23(9-15-26)16-17-33-22-28(24-10-12-25(13-11-24)29(30,31)32)36-20-18-35(19-21-36)27-6-4-3-5-7-27/h3-15,28,33H,16-22H2,1-2H3
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605n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162409
PNG
(CHEMBL191959 | [2-(4-tert-Butyl-phenyl)-ethyl]-[2-...)
Show SMILES COc1ccc(cc1)C(CNCCc1ccc(cc1)C(C)(C)C)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C31H47N3O/c1-31(2,3)27-14-10-25(11-15-27)18-19-32-24-30(26-12-16-29(35-4)17-13-26)34-22-20-33(21-23-34)28-8-6-5-7-9-28/h10-17,28,30,32H,5-9,18-24H2,1-4H3
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629n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162428
PNG
(CHEMBL193633 | [2-(4-tert-Butyl-phenyl)-2-(4-pheny...)
Show SMILES COc1ccc(CCNCC(N2CCN(CC2)c2ccccc2)c2ccc(cc2)C(C)(C)C)cc1
Show InChI InChI=1S/C31H41N3O/c1-31(2,3)27-14-12-26(13-15-27)30(24-32-19-18-25-10-16-29(35-4)17-11-25)34-22-20-33(21-23-34)28-8-6-5-7-9-28/h5-17,30,32H,18-24H2,1-4H3
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768n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162360
PNG
(CHEMBL372858 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES FC(F)(F)c1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C28H35F6N3/c29-27(30,31)23-10-6-21(7-11-23)14-15-35-20-26(22-8-12-24(13-9-22)28(32,33)34)37-18-16-36(17-19-37)25-4-2-1-3-5-25/h6-13,25-26,35H,1-5,14-20H2
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782n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162433
PNG
(1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-methoxy-ph...)
Show SMILES COc1ccc(cc1)C(CNC(=O)Nc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C26H34Cl2N4O2/c1-34-24-9-7-19(8-10-24)25(18-29-26(33)30-22-16-20(27)15-21(28)17-22)32-13-11-31(12-14-32)23-5-3-2-4-6-23/h7-10,15-17,23,25H,2-6,11-14,18H2,1H3,(H2,29,30,33)
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830n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162380
PNG
(CHEMBL179752 | [2-(4-tert-Butyl-phenyl)-ethyl]-[2-...)
Show SMILES CC(C)(C)c1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C31H44F3N3/c1-30(2,3)26-13-9-24(10-14-26)17-18-35-23-29(25-11-15-27(16-12-25)31(32,33)34)37-21-19-36(20-22-37)28-7-5-4-6-8-28/h9-16,28-29,35H,4-8,17-23H2,1-3H3
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832n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162391
PNG
(CHEMBL192412 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES Fc1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C27H35F4N3/c28-24-12-6-21(7-13-24)14-15-32-20-26(22-8-10-23(11-9-22)27(29,30)31)34-18-16-33(17-19-34)25-4-2-1-3-5-25/h6-13,25-26,32H,1-5,14-20H2
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895n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162348
PNG
(1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(2-methoxy-ph...)
Show SMILES COc1ccccc1C(CNC(=O)Nc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C26H34Cl2N4O2/c1-34-25-10-6-5-9-23(25)24(18-29-26(33)30-21-16-19(27)15-20(28)17-21)32-13-11-31(12-14-32)22-7-3-2-4-8-22/h5-6,9-10,15-17,22,24H,2-4,7-8,11-14,18H2,1H3,(H2,29,30,33)
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897n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162417
PNG
(1-(4-tert-Butyl-phenyl)-3-[2-(4-cyclohexyl-piperaz...)
Show SMILES COc1ccc(cc1)C(CNC(=O)Nc1ccc(cc1)C(C)(C)C)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C30H44N4O2/c1-30(2,3)24-12-14-25(15-13-24)32-29(35)31-22-28(23-10-16-27(36-4)17-11-23)34-20-18-33(19-21-34)26-8-6-5-7-9-26/h10-17,26,28H,5-9,18-22H2,1-4H3,(H2,31,32,35)
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910n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162419
PNG
(CHEMBL193809 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES COc1ccc(cc1)C(CNCCc1ccc(C)cc1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C28H41N3O/c1-23-8-10-24(11-9-23)16-17-29-22-28(25-12-14-27(32-2)15-13-25)31-20-18-30(19-21-31)26-6-4-3-5-7-26/h8-15,26,28-29H,3-7,16-22H2,1-2H3
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914n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162389
PNG
(CHEMBL363181 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES COc1ccc(cc1)C(CNCCc1ccc(cc1)C(F)(F)F)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C28H38F3N3O/c1-35-26-13-9-23(10-14-26)27(34-19-17-33(18-20-34)25-5-3-2-4-6-25)21-32-16-15-22-7-11-24(12-8-22)28(29,30)31/h7-14,25,27,32H,2-6,15-21H2,1H3
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929n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162362
PNG
(1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluorom...)
Show SMILES FC(F)(F)c1ccc(cc1)C(CNC(=O)Nc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C26H31Cl2F3N4O/c27-20-14-21(28)16-22(15-20)33-25(36)32-17-24(18-6-8-19(9-7-18)26(29,30)31)35-12-10-34(11-13-35)23-4-2-1-3-5-23/h6-9,14-16,23-24H,1-5,10-13,17H2,(H2,32,33,36)
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932n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162388
PNG
(1-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperaz...)
Show SMILES CC(C)(C)c1ccc(cc1)C(CNC(=O)Nc1ccc(cc1)C(F)(F)F)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C30H41F3N4O/c1-29(2,3)23-11-9-22(10-12-23)27(37-19-17-36(18-20-37)26-7-5-4-6-8-26)21-34-28(38)35-25-15-13-24(14-16-25)30(31,32)33/h9-16,26-27H,4-8,17-21H2,1-3H3,(H2,34,35,38)
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972n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162397
PNG
(1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-dimethylam...)
Show SMILES CN(C)c1ccc(cc1)C(CNC(=O)Nc1cc(Cl)cc(Cl)c1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C27H37Cl2N5O/c1-32(2)24-10-8-20(9-11-24)26(19-30-27(35)31-23-17-21(28)16-22(29)18-23)34-14-12-33(13-15-34)25-6-4-3-5-7-25/h8-11,16-18,25-26H,3-7,12-15,19H2,1-2H3,(H2,30,31,35)
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987n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162395
PNG
(1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-methoxy-ph...)
Show SMILES COc1ccc(cc1)C(CNC(=O)Nc1ccc(F)cc1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C26H35FN4O2/c1-33-24-13-7-20(8-14-24)25(19-28-26(32)29-22-11-9-21(27)10-12-22)31-17-15-30(16-18-31)23-5-3-2-4-6-23/h7-14,23,25H,2-6,15-19H2,1H3,(H2,28,29,32)
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1.03E+3n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162401
PNG
(CHEMBL372496 | [2-(4-Cyclohexyl-piperazin-1-yl)-2-...)
Show SMILES COc1ccc(cc1)C(CNCCc1ccccc1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C27H39N3O/c1-31-26-14-12-24(13-15-26)27(22-28-17-16-23-8-4-2-5-9-23)30-20-18-29(19-21-30)25-10-6-3-7-11-25/h2,4-5,8-9,12-15,25,27-28H,3,6-7,10-11,16-22H2,1H3
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1.04E+3n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162429
PNG
(1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluorom...)
Show SMILES Cc1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C27H35F3N4O/c1-20-7-13-23(14-8-20)32-26(35)31-19-25(21-9-11-22(12-10-21)27(28,29)30)34-17-15-33(16-18-34)24-5-3-2-4-6-24/h7-14,24-25H,2-6,15-19H2,1H3,(H2,31,32,35)
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1.07E+3n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162400
PNG
((4-{2-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-triflu...)
Show SMILES CN(C)c1ccc(CCNCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C29H41F3N4/c1-34(2)26-14-8-23(9-15-26)16-17-33-22-28(24-10-12-25(13-11-24)29(30,31)32)36-20-18-35(19-21-36)27-6-4-3-5-7-27/h8-15,27-28,33H,3-7,16-22H2,1-2H3
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1.08E+3n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162392
PNG
(1-[2-(4-Cyclohexyl-piperazin-1-yl)-2-(4-trifluorom...)
Show SMILES Fc1ccc(NC(=O)NCC(N2CCN(CC2)C2CCCCC2)c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C26H32F4N4O/c27-21-10-12-22(13-11-21)32-25(35)31-18-24(19-6-8-20(9-7-19)26(28,29)30)34-16-14-33(15-17-34)23-4-2-1-3-5-23/h6-13,23-24H,1-5,14-18H2,(H2,31,32,35)
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1.11E+3n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162387
PNG
(1-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperaz...)
Show SMILES CC(C)(C)c1ccc(cc1)C(CNC(=O)Nc1ccc(F)cc1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C29H41FN4O/c1-29(2,3)23-11-9-22(10-12-23)27(21-31-28(35)32-25-15-13-24(30)14-16-25)34-19-17-33(18-20-34)26-7-5-4-6-8-26/h9-16,26-27H,4-8,17-21H2,1-3H3,(H2,31,32,35)
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1.12E+3n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162421
PNG
(1-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperaz...)
Show SMILES CC(C)(C)c1ccc(cc1)C(CNC(=O)Nc1ccccc1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C29H42N4O/c1-29(2,3)24-16-14-23(15-17-24)27(22-30-28(34)31-25-10-6-4-7-11-25)33-20-18-32(19-21-33)26-12-8-5-9-13-26/h4,6-7,10-11,14-17,26-27H,5,8-9,12-13,18-22H2,1-3H3,(H2,30,31,34)
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1.13E+3n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162347
PNG
(CHEMBL194885 | [2-(4-Fluoro-phenyl)-ethyl]-[2-(4-p...)
Show SMILES Fc1ccc(CCNCC(N2CCN(CC2)c2ccccc2)c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C27H29F4N3/c28-24-12-6-21(7-13-24)14-15-32-20-26(22-8-10-23(11-9-22)27(29,30)31)34-18-16-33(17-19-34)25-4-2-1-3-5-25/h1-13,26,32H,14-20H2
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1.20E+3n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair
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