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Compile Data Set for Download or QSAR

Found 3 hits from Biota Scientific Management Pty. Ltd.   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA polymerase (alpha/delta/epsilon)


(Homo sapiens)
BDBM50021053
PNG
(CHEMBL3287609)
Show SMILES C[C@@]1(O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1c1ccc2c(N)ncnn12
Show InChI InChI=1S/C12H19N4O13P3/c1-12(18)9(17)8(4-26-31(22,23)29-32(24,25)28-30(19,20)21)27-10(12)6-2-3-7-11(13)14-5-15-16(6)7/h2-3,5,8-10,17-18H,4H2,1H3,(H,22,23)(H,24,25)(H2,13,14,15)(H2,19,20,21)/t8-,9-,10+,12-/m1/s1
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PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Biota Scientific Management Pty. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human DNA polymerase alpha


ACS Med Chem Lett 5: 679-84 (2014)


Article DOI: 10.1021/ml500077j
BindingDB Entry DOI: 10.7270/Q2B56MBN
More data for this
Ligand-Target Pair
DNA polymerase gamma subunit 1


(Homo sapiens (human))
BDBM50021053
PNG
(CHEMBL3287609)
Show SMILES C[C@@]1(O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1c1ccc2c(N)ncnn12
Show InChI InChI=1S/C12H19N4O13P3/c1-12(18)9(17)8(4-26-31(22,23)29-32(24,25)28-30(19,20)21)27-10(12)6-2-3-7-11(13)14-5-15-16(6)7/h2-3,5,8-10,17-18H,4H2,1H3,(H,22,23)(H,24,25)(H2,13,14,15)(H2,19,20,21)/t8-,9-,10+,12-/m1/s1
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KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Biota Scientific Management Pty. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human DNA polymerase gamma


ACS Med Chem Lett 5: 679-84 (2014)


Article DOI: 10.1021/ml500077j
BindingDB Entry DOI: 10.7270/Q2B56MBN
More data for this
Ligand-Target Pair
DNA polymerase beta


(Homo sapiens)
BDBM50021053
PNG
(CHEMBL3287609)
Show SMILES C[C@@]1(O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1c1ccc2c(N)ncnn12
Show InChI InChI=1S/C12H19N4O13P3/c1-12(18)9(17)8(4-26-31(22,23)29-32(24,25)28-30(19,20)21)27-10(12)6-2-3-7-11(13)14-5-15-16(6)7/h2-3,5,8-10,17-18H,4H2,1H3,(H,22,23)(H,24,25)(H2,13,14,15)(H2,19,20,21)/t8-,9-,10+,12-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Biota Scientific Management Pty. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human DNA polymerase beta


ACS Med Chem Lett 5: 679-84 (2014)


Article DOI: 10.1021/ml500077j
BindingDB Entry DOI: 10.7270/Q2B56MBN
More data for this
Ligand-Target Pair