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Compile Data Set for Download or QSAR

Found 110 hits from Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223480
PNG
(US9320734, PtdIns(3,4,5)trisphosphate)
Show SMILES CCCCCCCCCCCCCCCC(=O)OCC(COP([O-])(=O)OC1[C@H](O)[C@H](OP([O-])([O-])=O)C(OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H]1O)OC(=O)CCCCCCCCCCCCCCC
Show InChI InChI=1S/C41H82O22P4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)57-31-33(59-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-58-67(55,56)63-38-36(44)39(60-64(46,47)48)41(62-66(52,53)54)40(37(38)45)61-65(49,50)51/h33,36-41,44-45H,3-32H2,1-2H3,(H,55,56)(H2,46,47,48)(H2,49,50,51)(H2,52,53,54)/p-7/t33?,36-,37-,38?,39-,40+,41?/m0/s1
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260n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304369
PNG
(4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonam...)
Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)
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2.40E+3n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304369
PNG
(4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonam...)
Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)
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2.40E+3n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50338949
PNG
(4-Tetradecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfo...)
Show SMILES CCCCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C22H35N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-20-15-17-21(18-16-20)29(26,27)25-22-24-23-19-28-22/h15-19H,2-14H2,1H3,(H,24,25)
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6.70E+3n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50338950
PNG
(4-Hexadecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfon...)
Show SMILES CCCCCCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C24H39N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22-17-19-23(20-18-22)31(28,29)27-24-26-25-21-30-24/h17-21H,2-16H2,1H3,(H,26,27)
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6.90E+3n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50338948
PNG
(4-Octyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamid...)
Show SMILES CCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C16H23N3O2S2/c1-2-3-4-5-6-7-8-14-9-11-15(12-10-14)23(20,21)19-16-18-17-13-22-16/h9-13H,2-8H2,1H3,(H,18,19)
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8.40E+3n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50338951
PNG
(4-Octadecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfon...)
Show SMILES CCCCCCCCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C26H43N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24-19-21-25(22-20-24)33(30,31)29-26-28-27-23-32-26/h19-23H,2-18H2,1H3,(H,28,29)
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1.14E+4n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304368
PNG
(CHEMBL595582 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...)
Show SMILES CCCCCCCCCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C18H26N4O3S2/c1-2-3-4-5-6-7-8-9-17(23)20-15-10-12-16(13-11-15)27(24,25)22-18-21-19-14-26-18/h10-14H,2-9H2,1H3,(H,20,23)(H,21,22)
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2.18E+4n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304370
PNG
(CHEMBL593946 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C10H10N4O3S2/c1-7(15)12-8-2-4-9(5-3-8)19(16,17)14-10-13-11-6-18-10/h2-6H,1H3,(H,12,15)(H,13,14)
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>5.00E+4n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304371
PNG
(CHEMBL611216 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...)
Show SMILES COCCOCCOCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C15H20N4O6S2/c1-23-6-7-24-8-9-25-10-14(20)17-12-2-4-13(5-3-12)27(21,22)19-15-18-16-11-26-15/h2-5,11H,6-10H2,1H3,(H,17,20)(H,18,19)
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>5.00E+4n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50034417
PNG
(4-Amino-N-[1,3,4]thiadiazol-2-yl-benzenesulfonamid...)
Show SMILES Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C8H8N4O2S2/c9-6-1-3-7(4-2-6)16(13,14)12-8-11-10-5-15-8/h1-5H,9H2,(H,11,12)
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>5.00E+4n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50338946
PNG
(4-Butyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamid...)
Show SMILES CCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C12H15N3O2S2/c1-2-3-4-10-5-7-11(8-6-10)19(16,17)15-12-14-13-9-18-12/h5-9H,2-4H2,1H3,(H,14,15)
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>5.00E+4n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50338947
PNG
(4-Hexyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamid...)
Show SMILES CCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C14H19N3O2S2/c1-2-3-4-5-6-12-7-9-13(10-8-12)21(18,19)17-14-16-15-11-20-14/h7-11H,2-6H2,1H3,(H,16,17)
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>5.00E+4n/an/an/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223474
PNG
(US9320734, 415)
Show SMILES COc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3c(C)noc3C)cc2)nc(OC)n1
Show InChI InChI=1S/C17H19N5O7S2/c1-10-16(11(2)29-20-10)31(25,26)21-12-5-7-13(8-6-12)30(23,24)22-14-9-15(27-3)19-17(18-14)28-4/h5-9,21H,1-4H3,(H,18,19,22)
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n/an/a 1.00E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223476
PNG
(US9320734, 389)
Show SMILES CC1=NN(C(=O)c2ccc(Cl)cc2)C(=O)C1\N=N\c1ccc(cc1)S(=O)(=O)Nc1nnc(C)s1
Show InChI InChI=1S/C20H16ClN7O4S2/c1-11-17(19(30)28(26-11)18(29)13-3-5-14(21)6-4-13)24-23-15-7-9-16(10-8-15)34(31,32)27-20-25-22-12(2)33-20/h3-10,17H,1-2H3,(H,25,27)/b24-23+
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n/an/a 5.00E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304369
PNG
(4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonam...)
Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)
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n/an/a 6.30E+3n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304368
PNG
(CHEMBL595582 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...)
Show SMILES CCCCCCCCCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C18H26N4O3S2/c1-2-3-4-5-6-7-8-9-17(23)20-15-10-12-16(13-11-15)27(24,25)22-18-21-19-14-26-18/h10-14H,2-9H2,1H3,(H,20,23)(H,21,22)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304369
PNG
(4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonam...)
Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304368
PNG
(CHEMBL595582 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...)
Show SMILES CCCCCCCCCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C18H26N4O3S2/c1-2-3-4-5-6-7-8-9-17(23)20-15-10-12-16(13-11-15)27(24,25)22-18-21-19-14-26-18/h10-14H,2-9H2,1H3,(H,20,23)(H,21,22)
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n/an/a 1.50E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50034417
PNG
(4-Amino-N-[1,3,4]thiadiazol-2-yl-benzenesulfonamid...)
Show SMILES Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C8H8N4O2S2/c9-6-1-3-7(4-2-6)16(13,14)12-8-11-10-5-15-8/h1-5H,9H2,(H,11,12)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blotting using specific antibodies against phospho-Ser473-AKT in MiaPaCa-2 cells.Inhibition of AKT was meas...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50034417
PNG
(4-Amino-N-[1,3,4]thiadiazol-2-yl-benzenesulfonamid...)
Show SMILES Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C8H8N4O2S2/c9-6-1-3-7(4-2-6)16(13,14)12-8-11-10-5-15-8/h1-5H,9H2,(H,11,12)
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Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223477
PNG
(US9320734, 316)
Show SMILES CC1=NN(C(=O)c2ccc(Cl)cc2)C(=O)C1\N=N\c1ccc(cc1)S(=O)(=O)Nc1ncccn1
Show InChI InChI=1S/C21H16ClN7O4S/c1-13-18(20(31)29(27-13)19(30)14-3-5-15(22)6-4-14)26-25-16-7-9-17(10-8-16)34(32,33)28-21-23-11-2-12-24-21/h2-12,18H,1H3,(H,23,24,28)/b26-25+
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n/an/a 2.40E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223482
PNG
(US9320734, 441)
Show SMILES CCOc1ccccc1C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C16H15NO4/c1-2-21-14-10-6-4-8-12(14)15(18)17-13-9-5-3-7-11(13)16(19)20/h3-10H,2H2,1H3,(H,17,18)(H,19,20)
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n/an/a 2.50E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blotting using specific antibodies against phospho-Ser473-AKT in MiaPaCa-2 cells.Inhibition of AKT was meas...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304367
PNG
(CHEMBL595786 | N-(4-(N-(5-methyl-1,3,4-thiadiazol-...)
Show SMILES Cc1nnc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc2)s1
Show InChI InChI=1S/C19H16N4O4S3/c1-13-20-21-19(28-13)23-29(24,25)17-10-7-16(8-11-17)22-30(26,27)18-9-6-14-4-2-3-5-15(14)12-18/h2-12,22H,1H3,(H,21,23)
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Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blotting using specific antibodies against phospho-Ser473-AKT in MiaPaCa-2 cells.Inhibition of AKT was meas...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50034417
PNG
(4-Amino-N-[1,3,4]thiadiazol-2-yl-benzenesulfonamid...)
Show SMILES Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C8H8N4O2S2/c9-6-1-3-7(4-2-6)16(13,14)12-8-11-10-5-15-8/h1-5H,9H2,(H,11,12)
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Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304370
PNG
(CHEMBL593946 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C10H10N4O3S2/c1-7(15)12-8-2-4-9(5-3-8)19(16,17)14-10-13-11-6-18-10/h2-6H,1H3,(H,12,15)(H,13,14)
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Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223483
PNG
(US9320734, 445)
Show SMILES COc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccco3)cc2)nc(OC)n1
Show InChI InChI=1S/C17H16N4O6S/c1-25-15-10-14(19-17(20-15)26-2)21-28(23,24)12-7-5-11(6-8-12)18-16(22)13-4-3-9-27-13/h3-10H,1-2H3,(H,18,22)(H,19,20,21)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blotting using specific antibodies against phospho-Ser473-AKT in MiaPaCa-2 cells.Inhibition of AKT was meas...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223473
PNG
(US9320734, 444)
Show SMILES COc1cc(NS(=O)(=O)c2ccc(Nc3ccco3)cc2)nc(OC)n1
Show InChI InChI=1S/C16H16N4O5S/c1-23-15-10-13(18-16(19-15)24-2)20-26(21,22)12-7-5-11(6-8-12)17-14-4-3-9-25-14/h3-10,17H,1-2H3,(H,18,19,20)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blotting using specific antibodies against phospho-Ser473-AKT in MiaPaCa-2 cells.Inhibition of AKT was meas...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223475
PNG
(US9320734, 345)
Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2cccc3cccnc23)s1
Show InChI InChI=1S/C11H9N5O4S3/c12-22(17,18)11-15-14-10(21-11)16-23(19,20)8-5-1-3-7-4-2-6-13-9(7)8/h1-6H,(H,14,16)(H2,12,17,18)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223485
PNG
(US9320734, 456)
Show SMILES Nc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C14H14N6O6S4/c15-9-1-5-11(6-2-9)29(23,24)19-10-3-7-12(8-4-10)30(25,26)20-13-17-18-14(27-13)28(16,21)22/h1-8,19H,15H2,(H,17,20)(H2,16,21,22)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blotting using specific antibodies against phospho-Ser473-AKT in MiaPaCa-2 cells.Inhibition of AKT was meas...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223481
PNG
(US9320734, 439)
Show SMILES OC(=O)c1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccccc1
Show InChI InChI=1S/C21H16N2O4/c24-19(15-10-4-5-11-16(15)21(26)27)23-18-13-7-6-12-17(18)20(25)22-14-8-2-1-3-9-14/h1-13H,(H,22,25)(H,23,24)(H,26,27)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blotting using specific antibodies against phospho-Ser473-AKT in MiaPaCa-2 cells.Inhibition of AKT was meas...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304371
PNG
(CHEMBL611216 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...)
Show SMILES COCCOCCOCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C15H20N4O6S2/c1-23-6-7-24-8-9-25-10-14(20)17-12-2-4-13(5-3-12)27(21,22)19-15-18-16-11-26-15/h2-5,11H,6-10H2,1H3,(H,17,20)(H,18,19)
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Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223484
PNG
(US9320734, 450)
Show SMILES COc1cc(NS(=O)(=O)c2ccc(NC(C)=O)cc2)nc(OC)n1
Show InChI InChI=1S/C14H16N4O5S/c1-9(19)15-10-4-6-11(7-5-10)24(20,21)18-12-8-13(22-2)17-14(16-12)23-3/h4-8H,1-3H3,(H,15,19)(H,16,17,18)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
Inhibition of AKT was measured by Western blotting using specific antibodies against phospho-Ser473-AKT in MiaPaCa-2 cells.Inhibition of AKT was meas...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223477
PNG
(US9320734, 316)
Show SMILES CC1=NN(C(=O)c2ccc(Cl)cc2)C(=O)C1\N=N\c1ccc(cc1)S(=O)(=O)Nc1ncccn1
Show InChI InChI=1S/C21H16ClN7O4S/c1-13-18(20(31)29(27-13)19(30)14-3-5-15(22)6-4-14)26-25-16-7-9-17(10-8-16)34(32,33)28-21-23-11-2-12-24-21/h2-12,18H,1H3,(H,23,24,28)/b26-25+
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n/an/an/a 390n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223475
PNG
(US9320734, 345)
Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2cccc3cccnc23)s1
Show InChI InChI=1S/C11H9N5O4S3/c12-22(17,18)11-15-14-10(21-11)16-23(19,20)8-5-1-3-7-4-2-6-13-9(7)8/h1-6H,(H,14,16)(H2,12,17,18)
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n/an/an/a 1.79E+3n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223476
PNG
(US9320734, 389)
Show SMILES CC1=NN(C(=O)c2ccc(Cl)cc2)C(=O)C1\N=N\c1ccc(cc1)S(=O)(=O)Nc1nnc(C)s1
Show InChI InChI=1S/C20H16ClN7O4S2/c1-11-17(19(30)28(26-11)18(29)13-3-5-14(21)6-4-13)24-23-15-7-9-16(10-8-15)34(31,32)27-20-25-22-12(2)33-20/h3-10,17H,1-2H3,(H,25,27)/b24-23+
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n/an/an/a 4.58E+3n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223474
PNG
(US9320734, 415)
Show SMILES COc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3c(C)noc3C)cc2)nc(OC)n1
Show InChI InChI=1S/C17H19N5O7S2/c1-10-16(11(2)29-20-10)31(25,26)21-12-5-7-13(8-6-12)30(23,24)22-14-9-15(27-3)19-17(18-14)28-4/h5-9,21H,1-4H3,(H,18,19,22)
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n/an/an/a 6.27E+3n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50034417
PNG
(4-Amino-N-[1,3,4]thiadiazol-2-yl-benzenesulfonamid...)
Show SMILES Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C8H8N4O2S2/c9-6-1-3-7(4-2-6)16(13,14)12-8-11-10-5-15-8/h1-5H,9H2,(H,11,12)
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Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304368
PNG
(CHEMBL595582 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...)
Show SMILES CCCCCCCCCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C18H26N4O3S2/c1-2-3-4-5-6-7-8-9-17(23)20-15-10-12-16(13-11-15)27(24,25)22-18-21-19-14-26-18/h10-14H,2-9H2,1H3,(H,20,23)(H,21,22)
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n/an/an/a 1.02E+4n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304370
PNG
(CHEMBL593946 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C10H10N4O3S2/c1-7(15)12-8-2-4-9(5-3-8)19(16,17)14-10-13-11-6-18-10/h2-6H,1H3,(H,12,15)(H,13,14)
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Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304371
PNG
(CHEMBL611216 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...)
Show SMILES COCCOCCOCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C15H20N4O6S2/c1-23-6-7-24-8-9-25-10-14(20)17-12-2-4-13(5-3-12)27(21,22)19-15-18-16-11-26-15/h2-5,11H,6-10H2,1H3,(H,17,20)(H,18,19)
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n/an/an/a 2.04E+4n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304369
PNG
(4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonam...)
Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)
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Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50034417
PNG
(4-Amino-N-[1,3,4]thiadiazol-2-yl-benzenesulfonamid...)
Show SMILES Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C8H8N4O2S2/c9-6-1-3-7(4-2-6)16(13,14)12-8-11-10-5-15-8/h1-5H,9H2,(H,11,12)
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n/an/an/a 450n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304368
PNG
(CHEMBL595582 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...)
Show SMILES CCCCCCCCCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C18H26N4O3S2/c1-2-3-4-5-6-7-8-9-17(23)20-15-10-12-16(13-11-15)27(24,25)22-18-21-19-14-26-18/h10-14H,2-9H2,1H3,(H,20,23)(H,21,22)
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n/an/an/a 1.96E+4n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304369
PNG
(4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonam...)
Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)
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n/an/an/a 4.08E+4n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50304369
PNG
(4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonam...)
Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Show InChI InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)
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n/an/an/a 1.35E+4n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50338952
PNG
(4-Dodecyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzen...)
Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nnc(C)s1
Show InChI InChI=1S/C21H33N3O2S2/c1-3-4-5-6-7-8-9-10-11-12-13-19-14-16-20(17-15-19)28(25,26)24-21-23-22-18(2)27-21/h14-17H,3-13H2,1-2H3,(H,23,24)
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n/an/an/a 8.32E+3n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50338953
PNG
(4-Dodecyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzene...)
Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nnc(CC)s1
Show InChI InChI=1S/C22H35N3O2S2/c1-3-5-6-7-8-9-10-11-12-13-14-19-15-17-20(18-16-19)29(26,27)25-22-24-23-21(4-2)28-22/h15-18H,3-14H2,1-2H3,(H,24,25)
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n/an/an/a 7.59E+3n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM50338954
PNG
(CHEMBL1685054 | N-(5-tert-Butyl-1,3,4-thiadiazol-2...)
Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nnc(s1)C(C)(C)C
Show InChI InChI=1S/C24H39N3O2S2/c1-5-6-7-8-9-10-11-12-13-14-15-20-16-18-21(19-17-20)31(28,29)27-23-26-25-22(30-23)24(2,3)4/h16-19H,5-15H2,1-4H3,(H,26,27)
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n/an/an/a 4.07E+3n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Akt)


(Homo sapiens (Human))
BDBM223478
PNG
(US9320734, 110)
Show SMILES CCc1nnc(NS(=O)(=O)c2ccc(NC(C)=O)cc2)s1
Show InChI InChI=1S/C12H14N4O3S2/c1-3-11-14-15-12(20-11)16-21(18,19)10-6-4-9(5-7-10)13-8(2)17/h4-7H,3H2,1-2H3,(H,13,17)(H,15,16)
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n/an/an/a 6.03E+3n/an/an/an/an/a



Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona

US Patent


Assay Description
SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...


US Patent US9320734 (2016)


BindingDB Entry DOI: 10.7270/Q2QF8RRM
More data for this
Ligand-Target Pair
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