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Compile Data Set for Download or QSAR

Found 81 hits from Brandeis University   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398421
PNG
(CHEMBL2178616)
Show SMILES CC(N=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C18H19ClN4O4/c1-11(22-25)12-5-4-6-13(9-12)18(2,3)21-17(24)20-14-7-8-15(19)16(10-14)23(26)27/h4-11H,1-3H3,(H2,20,21,24)
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n/an/a 0.660n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398409
PNG
(CHEMBL2178626)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2cccnc2c1
Show InChI InChI=1S/C22H23N3O/c1-15(2)17-7-5-9-18(13-17)22(3,4)25-21(26)24-19-11-10-16-8-6-12-23-20(16)14-19/h5-14H,1H2,2-4H3,(H2,24,25,26)
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n/an/a 0.800n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398423
PNG
(CHEMBL2178619)
Show SMILES CC(N=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2cccnc2c1
Show InChI InChI=1S/C21H22N4O2/c1-14(25-27)16-6-4-8-17(12-16)21(2,3)24-20(26)23-18-10-9-15-7-5-11-22-19(15)13-18/h4-14H,1-3H3,(H2,23,24,26)
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n/an/a 0.900n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398419
PNG
(CHEMBL2178618)
Show SMILES CC(N=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C22H23N3O2/c1-15(25-27)17-9-6-10-19(13-17)22(2,3)24-21(26)23-20-12-11-16-7-4-5-8-18(16)14-20/h4-15H,1-3H3,(H2,23,24,26)
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n/an/a 1n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398414
PNG
(CHEMBL2178644)
Show SMILES CC(N=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C19H19ClF3N3O2/c1-11(26-28)12-5-4-6-13(9-12)18(2,3)25-17(27)24-14-7-8-16(20)15(10-14)19(21,22)23/h4-11H,1-3H3,(H2,24,25,27)
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n/an/a 1n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398423
PNG
(CHEMBL2178619)
Show SMILES CC(N=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2cccnc2c1
Show InChI InChI=1S/C21H22N4O2/c1-14(25-27)16-6-4-8-17(12-16)21(2,3)24-20(26)23-18-10-9-15-7-5-11-22-19(15)13-18/h4-14H,1-3H3,(H2,23,24,26)
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n/an/a 1.20n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398412
PNG
(CHEMBL2178653)
Show SMILES COc1cc(NC(=O)NC(C)(C)c2cccc(c2)C(C)=C)ccc1Cl
Show InChI InChI=1S/C20H23ClN2O2/c1-13(2)14-7-6-8-15(11-14)20(3,4)23-19(24)22-16-9-10-17(21)18(12-16)25-5/h6-12H,1H2,2-5H3,(H2,22,23,24)
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n/an/a 1.30n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398422
PNG
(CHEMBL2178622)
Show SMILES CO\N=C(/C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C23H25N3O2/c1-16(26-28-4)18-10-7-11-20(14-18)23(2,3)25-22(27)24-21-13-12-17-8-5-6-9-19(17)15-21/h5-15H,1-4H3,(H2,24,25,27)/b26-16+
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n/an/a 1.60n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398415
PNG
(CHEMBL2178625)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2ncccc2c1
Show InChI InChI=1S/C22H23N3O/c1-15(2)16-7-5-9-18(13-16)22(3,4)25-21(26)24-19-10-11-20-17(14-19)8-6-12-23-20/h5-14H,1H2,2-4H3,(H2,24,25,26)
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n/an/a 1.80n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398421
PNG
(CHEMBL2178616)
Show SMILES CC(N=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C18H19ClN4O4/c1-11(22-25)12-5-4-6-13(9-12)18(2,3)21-17(24)20-14-7-8-15(19)16(10-14)23(26)27/h4-11H,1-3H3,(H2,20,21,24)
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n/an/a 2n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398420
PNG
(CHEMBL2178658)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C23H24N2O/c1-16(2)18-10-7-11-20(14-18)23(3,4)25-22(26)24-21-13-12-17-8-5-6-9-19(17)15-21/h5-15H,1H2,2-4H3,(H2,24,25,26)
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n/an/a 2.10n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398419
PNG
(CHEMBL2178618)
Show SMILES CC(N=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C22H23N3O2/c1-15(25-27)17-9-6-10-19(13-17)22(2,3)24-21(26)23-20-12-11-16-7-4-5-8-18(16)14-20/h4-15H,1-3H3,(H2,23,24,26)
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n/an/a 2.30n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398418
PNG
(CHEMBL2178654)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(N)=O
Show InChI InChI=1S/C20H22ClN3O2/c1-12(2)13-6-5-7-14(10-13)20(3,4)24-19(26)23-15-8-9-17(21)16(11-15)18(22)25/h5-11H,1H2,2-4H3,(H2,22,25)(H2,23,24,26)
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n/an/a 2.30n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398418
PNG
(CHEMBL2178654)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(N)=O
Show InChI InChI=1S/C20H22ClN3O2/c1-12(2)13-6-5-7-14(10-13)20(3,4)24-19(26)23-15-8-9-17(21)16(11-15)18(22)25/h5-11H,1H2,2-4H3,(H2,22,25)(H2,23,24,26)
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n/an/a 3n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398415
PNG
(CHEMBL2178625)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2ncccc2c1
Show InChI InChI=1S/C22H23N3O/c1-15(2)16-7-5-9-18(13-16)22(3,4)25-21(26)24-19-10-11-20-17(14-19)8-6-12-23-20/h5-14H,1H2,2-4H3,(H2,24,25,26)
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n/an/a 4n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398414
PNG
(CHEMBL2178644)
Show SMILES CC(N=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C19H19ClF3N3O2/c1-11(26-28)12-5-4-6-13(9-12)18(2,3)25-17(27)24-14-7-8-16(20)15(10-14)19(21,22)23/h4-11H,1-3H3,(H2,24,25,27)
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n/an/a 4n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398416
PNG
(CHEMBL2178632)
Show SMILES CC(C)(NC(=O)Nc1ccc(Cl)c(c1)C(N)=O)c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C23H22ClN3O2/c1-23(2,17-10-6-9-16(13-17)15-7-4-3-5-8-15)27-22(29)26-18-11-12-20(24)19(14-18)21(25)28/h3-14H,1-2H3,(H2,25,28)(H2,26,27,29)
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n/an/a 4n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398417
PNG
(CHEMBL2178652)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C20H20ClF3N2O/c1-12(2)13-6-5-7-14(10-13)19(3,4)26-18(27)25-15-8-9-17(21)16(11-15)20(22,23)24/h5-11H,1H2,2-4H3,(H2,25,26,27)
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n/an/a 4n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398408
PNG
(CHEMBL2178617)
Show SMILES CC(N=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(N)=O
Show InChI InChI=1S/C19H21ClN4O3/c1-11(24-27)12-5-4-6-13(9-12)19(2,3)23-18(26)22-14-7-8-16(20)15(10-14)17(21)25/h4-11H,1-3H3,(H2,21,25)(H2,22,23,26)
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n/an/a 5n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398413
PNG
(CHEMBL2178620)
Show SMILES CO\N=C(/C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C20H21ClF3N3O2/c1-12(27-29-4)13-6-5-7-14(10-13)19(2,3)26-18(28)25-15-8-9-17(21)16(11-15)20(22,23)24/h5-11H,1-4H3,(H2,25,26,28)/b27-12+
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n/an/a 5n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398411
PNG
(CHEMBL2178621)
Show SMILES CO\N=C(/C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(N)=O
Show InChI InChI=1S/C20H23ClN4O3/c1-12(25-28-4)13-6-5-7-14(10-13)20(2,3)24-19(27)23-15-8-9-17(21)16(11-15)18(22)26/h5-11H,1-4H3,(H2,22,26)(H2,23,24,27)/b25-12+
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n/an/a 5n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398411
PNG
(CHEMBL2178621)
Show SMILES CO\N=C(/C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(N)=O
Show InChI InChI=1S/C20H23ClN4O3/c1-12(25-28-4)13-6-5-7-14(10-13)20(2,3)24-19(27)23-15-8-9-17(21)16(11-15)18(22)26/h5-11H,1-4H3,(H2,22,26)(H2,23,24,27)/b25-12+
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398412
PNG
(CHEMBL2178653)
Show SMILES COc1cc(NC(=O)NC(C)(C)c2cccc(c2)C(C)=C)ccc1Cl
Show InChI InChI=1S/C20H23ClN2O2/c1-13(2)14-7-6-8-15(11-14)20(3,4)23-19(24)22-16-9-10-17(21)18(12-16)25-5/h6-12H,1H2,2-5H3,(H2,22,23,24)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398410
PNG
(CHEMBL2178651)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H20Cl2N2O/c1-12(2)13-6-5-7-14(10-13)19(3,4)23-18(24)22-15-8-9-16(20)17(21)11-15/h5-11H,1H2,2-4H3,(H2,22,23,24)
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n/an/a 6n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398409
PNG
(CHEMBL2178626)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2cccnc2c1
Show InChI InChI=1S/C22H23N3O/c1-15(2)17-7-5-9-18(13-17)22(3,4)25-21(26)24-19-11-10-16-8-6-12-23-20(16)14-19/h5-14H,1H2,2-4H3,(H2,24,25,26)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398408
PNG
(CHEMBL2178617)
Show SMILES CC(N=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(N)=O
Show InChI InChI=1S/C19H21ClN4O3/c1-11(24-27)12-5-4-6-13(9-12)19(2,3)23-18(26)22-14-7-8-16(20)15(10-14)17(21)25/h4-11H,1-3H3,(H2,21,25)(H2,22,23,26)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398407
PNG
(CHEMBL2178655)
Show SMILES CNC(=O)c1cc(NC(=O)NC(C)(C)c2cccc(c2)C(C)=C)ccc1Cl
Show InChI InChI=1S/C21H24ClN3O2/c1-13(2)14-7-6-8-15(11-14)21(3,4)25-20(27)24-16-9-10-18(22)17(12-16)19(26)23-5/h6-12H,1H2,2-5H3,(H,23,26)(H2,24,25,27)
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n/an/a 7n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398406
PNG
(CHEMBL2178657)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2OCCOc2c1
Show InChI InChI=1S/C21H24N2O3/c1-14(2)15-6-5-7-16(12-15)21(3,4)23-20(24)22-17-8-9-18-19(13-17)26-11-10-25-18/h5-9,12-13H,1,10-11H2,2-4H3,(H2,22,23,24)
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n/an/a 7.20n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398402
PNG
(CHEMBL2178656)
Show SMILES CN(C)C(=O)c1cc(NC(=O)NC(C)(C)c2cccc(c2)C(C)=C)ccc1Cl
Show InChI InChI=1S/C22H26ClN3O2/c1-14(2)15-8-7-9-16(12-15)22(3,4)25-21(28)24-17-10-11-19(23)18(13-17)20(27)26(5)6/h7-13H,1H2,2-6H3,(H2,24,25,28)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398404
PNG
(CHEMBL2178635)
Show SMILES CC(=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C19H18ClF3N2O2/c1-11(26)12-5-4-6-13(9-12)18(2,3)25-17(27)24-14-7-8-16(20)15(10-14)19(21,22)23/h4-10H,1-3H3,(H2,24,25,27)
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n/an/a 9n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398405
PNG
(CHEMBL1606928)
Show SMILES COc1ccc(NC(=O)NC(C)(C)c2cccc(c2)C(C)=C)cc1
Show InChI InChI=1S/C20H24N2O2/c1-14(2)15-7-6-8-16(13-15)20(3,4)22-19(23)21-17-9-11-18(24-5)12-10-17/h6-13H,1H2,2-5H3,(H2,21,22,23)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398403
PNG
(CHEMBL2178647)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C19H21BrN2O/c1-13(2)14-6-5-7-15(12-14)19(3,4)22-18(23)21-17-10-8-16(20)9-11-17/h5-12H,1H2,2-4H3,(H2,21,22,23)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398402
PNG
(CHEMBL2178656)
Show SMILES CN(C)C(=O)c1cc(NC(=O)NC(C)(C)c2cccc(c2)C(C)=C)ccc1Cl
Show InChI InChI=1S/C22H26ClN3O2/c1-14(2)15-8-7-9-16(12-15)22(3,4)25-21(28)24-17-10-11-19(23)18(13-17)20(27)26(5)6/h7-13H,1H2,2-6H3,(H2,24,25,28)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398422
PNG
(CHEMBL2178622)
Show SMILES CO\N=C(/C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C23H25N3O2/c1-16(26-28-4)18-10-7-11-20(14-18)23(2,3)25-22(27)24-21-13-12-17-8-5-6-9-19(17)15-21/h5-15H,1-4H3,(H2,24,25,27)/b26-16+
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n/an/a 13n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398407
PNG
(CHEMBL2178655)
Show SMILES CNC(=O)c1cc(NC(=O)NC(C)(C)c2cccc(c2)C(C)=C)ccc1Cl
Show InChI InChI=1S/C21H24ClN3O2/c1-13(2)14-7-6-8-15(11-14)21(3,4)25-20(27)24-16-9-10-18(22)17(12-16)19(26)23-5/h6-12H,1H2,2-5H3,(H,23,26)(H2,24,25,27)
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n/an/a 14n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398416
PNG
(CHEMBL2178632)
Show SMILES CC(C)(NC(=O)Nc1ccc(Cl)c(c1)C(N)=O)c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C23H22ClN3O2/c1-23(2,17-10-6-9-16(13-17)15-7-4-3-5-8-15)27-22(29)26-18-11-12-20(24)19(14-18)21(25)28/h3-14H,1-2H3,(H2,25,28)(H2,26,27,29)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398413
PNG
(CHEMBL2178620)
Show SMILES CO\N=C(/C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C20H21ClF3N3O2/c1-12(27-29-4)13-6-5-7-14(10-13)19(2,3)26-18(28)25-15-8-9-17(21)16(11-15)20(22,23)24/h5-11H,1-4H3,(H2,25,26,28)/b27-12+
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n/an/a 18n/an/an/an/an/an/a



Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398403
PNG
(CHEMBL2178647)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Br)cc1
Show InChI InChI=1S/C19H21BrN2O/c1-13(2)14-6-5-7-15(12-14)19(3,4)22-18(23)21-17-10-8-16(20)9-11-17/h5-12H,1H2,2-4H3,(H2,21,22,23)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398446
PNG
(CHEMBL2178623)
Show SMILES C[C-](N=[O+]CCN)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C20H24ClN5O4/c1-13(25-30-10-9-22)14-5-4-6-15(11-14)20(2,3)24-19(27)23-16-7-8-17(21)18(12-16)26(28)29/h4-8,11-12H,9-10,22H2,1-3H3,(H2,23,24,27)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398445
PNG
(CHEMBL2178646)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C19H21ClN2O/c1-13(2)14-6-5-7-15(12-14)19(3,4)22-18(23)21-17-10-8-16(20)9-11-17/h5-12H,1H2,2-4H3,(H2,21,22,23)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398417
PNG
(CHEMBL2178652)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C20H20ClF3N2O/c1-12(2)13-6-5-7-14(10-13)19(3,4)26-18(27)25-15-8-9-17(21)16(11-15)20(22,23)24/h5-11H,1H2,2-4H3,(H2,25,26,27)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398404
PNG
(CHEMBL2178635)
Show SMILES CC(=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C19H18ClF3N2O2/c1-11(26)12-5-4-6-13(9-12)18(2,3)25-17(27)24-14-7-8-16(20)15(10-14)19(21,22)23/h4-10H,1-3H3,(H2,24,25,27)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398405
PNG
(CHEMBL1606928)
Show SMILES COc1ccc(NC(=O)NC(C)(C)c2cccc(c2)C(C)=C)cc1
Show InChI InChI=1S/C20H24N2O2/c1-14(2)15-7-6-8-16(13-15)20(3,4)22-19(23)21-17-9-11-18(24-5)12-10-17/h6-13H,1H2,2-5H3,(H2,21,22,23)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398446
PNG
(CHEMBL2178623)
Show SMILES C[C-](N=[O+]CCN)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C20H24ClN5O4/c1-13(25-30-10-9-22)14-5-4-6-15(11-14)20(2,3)24-19(27)23-16-7-8-17(21)18(12-16)26(28)29/h4-8,11-12H,9-10,22H2,1-3H3,(H2,23,24,27)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398445
PNG
(CHEMBL2178646)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C19H21ClN2O/c1-13(2)14-6-5-7-15(12-14)19(3,4)22-18(23)21-17-10-8-16(20)9-11-17/h5-12H,1H2,2-4H3,(H2,21,22,23)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398435
PNG
(CHEMBL2178634)
Show SMILES CC(=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C18H19ClN2O2/c1-12(22)13-5-4-6-14(11-13)18(2,3)21-17(23)20-16-9-7-15(19)8-10-16/h4-11H,1-3H3,(H2,20,21,23)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398434
PNG
(CHEMBL2178639)
Show SMILES NC(=O)c1cc(NC(=O)NC2(CC2)c2cccc(c2)-c2ccccc2)ccc1Cl
Show InChI InChI=1S/C23H20ClN3O2/c24-20-10-9-18(14-19(20)21(25)28)26-22(29)27-23(11-12-23)17-8-4-7-16(13-17)15-5-2-1-3-6-15/h1-10,13-14H,11-12H2,(H2,25,28)(H2,26,27,29)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH incubated for 5 mins by fluoresce...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398420
PNG
(CHEMBL2178658)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C23H24N2O/c1-16(2)18-10-7-11-20(14-18)23(3,4)25-22(26)24-21-13-12-17-8-5-6-9-19(17)15-21/h5-15H,1H2,2-4H3,(H2,24,25,26)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398410
PNG
(CHEMBL2178651)
Show SMILES CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C19H20Cl2N2O/c1-12(2)13-6-5-7-14(10-13)19(3,4)23-18(24)22-15-8-9-16(20)17(21)11-15/h5-11H,1H2,2-4H3,(H2,22,23,24)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
Inosine-5-monophosphate dehydrogenase (IMPDH)


(Cryptosporidium parvum)
BDBM50398436
PNG
(CHEMBL2178636)
Show SMILES CC(=O)c1cccc(c1)C(C)(C)NC(=O)Nc1ccc(Cl)c(c1)C(N)=O
Show InChI InChI=1S/C19H20ClN3O3/c1-11(24)12-5-4-6-13(9-12)19(2,3)23-18(26)22-14-7-8-16(20)15(10-14)17(21)25/h4-10H,1-3H3,(H2,21,25)(H2,22,23,26)
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Brandeis University

Curated by ChEMBL


Assay Description
Inhibition of Cryptosporidium parvum recombinant IMPDH expressed in Escherichia coli assessed as production of NADH in presence of 0.05% fatty acid f...


J Med Chem 55: 7759-71 (2012)


Article DOI: 10.1021/jm3007917
BindingDB Entry DOI: 10.7270/Q2GM88GS
More data for this
Ligand-Target Pair
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