BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 43 hits from Bristol-Myers Squibb Pharma Research Laboratories   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145742
PNG
((R)-1-(2,4-Dichloro-phenylamino)-4-pyridin-4-yl-1-...)
Show SMILES Cc1ccccc1[C@@H](Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C22H20Cl2N2O/c1-15-4-2-3-5-18(15)22(26-20-8-7-17(23)14-19(20)24)21(27)9-6-16-10-12-25-13-11-16/h2-5,7-8,10-14,22,26H,6,9H2,1H3/t22-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
154n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145735
PNG
(1-(2-Bromo-phenyl)-1-(2,4-dichloro-phenylamino)-4-...)
Show SMILES Clc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C21H17BrCl2N2O/c22-17-4-2-1-3-16(17)21(26-19-7-6-15(23)13-18(19)24)20(27)8-5-14-9-11-25-12-10-14/h1-4,6-7,9-13,21,26H,5,8H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
204n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145751
PNG
((R)-1-(2-Chloro-4-methyl-phenylamino)-4-pyridin-4-...)
Show SMILES Cc1ccc(N[C@@H](C(=O)CCc2ccncc2)c2ccccc2C)c(Cl)c1
Show InChI InChI=1S/C23H23ClN2O/c1-16-7-9-21(20(24)15-16)26-23(19-6-4-3-5-17(19)2)22(27)10-8-18-11-13-25-14-12-18/h3-7,9,11-15,23,26H,8,10H2,1-2H3/t23-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
244n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145754
PNG
(1-(2,4-Dichloro-phenylamino)-1-(2-ethyl-phenyl)-4-...)
Show SMILES CCc1ccccc1C(Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C23H22Cl2N2O/c1-2-17-5-3-4-6-19(17)23(27-21-9-8-18(24)15-20(21)25)22(28)10-7-16-11-13-26-14-12-16/h3-6,8-9,11-15,23,27H,2,7,10H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
330n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145731
PNG
(1-(2,4-Dichloro-phenylamino)-1-(2,6-dimethyl-pheny...)
Show SMILES Cc1cccc(C)c1C(Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C23H22Cl2N2O/c1-15-4-3-5-16(2)22(15)23(27-20-8-7-18(24)14-19(20)25)21(28)9-6-17-10-12-26-13-11-17/h3-5,7-8,10-14,23,27H,6,9H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
338n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145749
PNG
(1-(2,4-Dichloro-phenylamino)-4-pyridin-4-yl-1-o-to...)
Show SMILES Cc1ccccc1C(Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C22H20Cl2N2O/c1-15-4-2-3-5-18(15)22(26-20-8-7-17(23)14-19(20)24)21(27)9-6-16-10-12-25-13-11-16/h2-5,7-8,10-14,22,26H,6,9H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
370n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145732
PNG
(2-(2,4-Dichloro-phenylamino)-1-(3-hydroxy-4-methox...)
Show SMILES COc1ccc(cc1O)C(=O)C(Nc1ccc(Cl)cc1Cl)c1ccccc1C
Show InChI InChI=1S/C22H19Cl2NO3/c1-13-5-3-4-6-16(13)21(25-18-9-8-15(23)12-17(18)24)22(27)14-7-10-20(28-2)19(26)11-14/h3-12,21,25-26H,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
387n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145745
PNG
(1-(2-Fluoro-4-methyl-phenylamino)-4-pyridin-4-yl-1...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2C)c(F)c1
Show InChI InChI=1S/C23H23FN2O/c1-16-7-9-21(20(24)15-16)26-23(19-6-4-3-5-17(19)2)22(27)10-8-18-11-13-25-14-12-18/h3-7,9,11-15,23,26H,8,10H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
439n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145758
PNG
(1-(4-Chloro-2-trifluoromethyl-phenylamino)-4-pyrid...)
Show SMILES Cc1ccccc1C(Nc1ccc(Cl)cc1C(F)(F)F)C(=O)CCc1ccncc1
Show InChI InChI=1S/C23H20ClF3N2O/c1-15-4-2-3-5-18(15)22(21(30)9-6-16-10-12-28-13-11-16)29-20-8-7-17(24)14-19(20)23(25,26)27/h2-5,7-8,10-14,22,29H,6,9H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
469n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145733
PNG
(1-(2,4-Dichloro-phenylamino)-1-(4-fluoro-2-methyl-...)
Show SMILES Cc1cc(F)ccc1C(Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C22H19Cl2FN2O/c1-14-12-17(25)4-5-18(14)22(27-20-6-3-16(23)13-19(20)24)21(28)7-2-15-8-10-26-11-9-15/h3-6,8-13,22,27H,2,7H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
512n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145739
PNG
(CHEMBL81912 | N-{3-[2-(2-Bromo-phenyl)-2-(2,4-dich...)
Show SMILES CC(=O)Nc1cccc(c1)C(=O)C(Nc1ccc(Cl)cc1Cl)c1ccccc1Br
Show InChI InChI=1S/C22H17BrCl2N2O2/c1-13(28)26-16-6-4-5-14(11-16)22(29)21(17-7-2-3-8-18(17)23)27-20-10-9-15(24)12-19(20)25/h2-12,21,27H,1H3,(H,26,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
514n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145741
PNG
((R)-1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenyl...)
Show SMILES Cc1ccc(N[C@@H](C(=O)CCc2ccncc2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C22H20BrClN2O/c1-15-6-8-20(19(24)14-15)26-22(17-4-2-3-5-18(17)23)21(27)9-7-16-10-12-25-13-11-16/h2-6,8,10-14,22,26H,7,9H2,1H3/t22-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
546n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity of compound towards human corticotropin releasing factor (h-CRF1) receptor showed a 2-fold activity in racemic mixture


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145755
PNG
(1-(4-Methyl-2-trifluoromethyl-phenylamino)-4-pyrid...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2C)c(c1)C(F)(F)F
Show InChI InChI=1S/C24H23F3N2O/c1-16-7-9-21(20(15-16)24(25,26)27)29-23(19-6-4-3-5-17(19)2)22(30)10-8-18-11-13-28-14-12-18/h3-7,9,11-15,23,29H,8,10H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
641n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145740
PNG
(1-(2-Chloro-4-methyl-phenylamino)-4-pyridin-4-yl-1...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2C=C)c(Cl)c1
Show InChI InChI=1S/C24H23ClN2O/c1-3-19-6-4-5-7-20(19)24(27-22-10-8-17(2)16-21(22)25)23(28)11-9-18-12-14-26-15-13-18/h3-8,10,12-16,24,27H,1,9,11H2,2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
752n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145729
PNG
(1-(2-Chloro-4-methyl-phenylamino)-4-pyridin-4-yl-1...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2C)c(Cl)c1
Show InChI InChI=1S/C23H23ClN2O/c1-16-7-9-21(20(24)15-16)26-23(19-6-4-3-5-17(19)2)22(27)10-8-18-11-13-25-14-12-18/h3-7,9,11-15,23,26H,8,10H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
922n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145759
PNG
(1-(2,4-Dichloro-phenylamino)-4-pyridin-4-yl-1-(2-t...)
Show SMILES FC(F)(F)c1ccccc1C(Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C22H17Cl2F3N2O/c23-15-6-7-19(18(24)13-15)29-21(16-3-1-2-4-17(16)22(25,26)27)20(30)8-5-14-9-11-28-12-10-14/h1-4,6-7,9-13,21,29H,5,8H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.00E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145730
PNG
(1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C22H20BrClN2O/c1-15-6-8-20(19(24)14-15)26-22(17-4-2-3-5-18(17)23)21(27)9-7-16-10-12-25-13-11-16/h2-6,8,10-14,22,26H,7,9H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.04E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity of compound towards human Corticotropin releasing factor receptor 1


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145737
PNG
(2-(2-Bromo-phenyl)-2-(2-chloro-4-methyl-phenylamin...)
Show SMILES COc1ccc(cc1O)C(=O)C(Nc1ccc(C)cc1Cl)c1ccccc1Br
Show InChI InChI=1S/C22H19BrClNO3/c1-13-7-9-18(17(24)11-13)25-21(15-5-3-4-6-16(15)23)22(27)14-8-10-20(28-2)19(26)12-14/h3-12,21,25-26H,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.07E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145764
PNG
(3-[2-(2-Bromo-phenyl)-2-(2-chloro-4-methyl-phenyla...)
Show SMILES CNC(=O)c1cccc(c1)C(=O)C(Nc1ccc(C)cc1Cl)c1ccccc1Br
Show InChI InChI=1S/C23H20BrClN2O2/c1-14-10-11-20(19(25)12-14)27-21(17-8-3-4-9-18(17)24)22(28)15-6-5-7-16(13-15)23(29)26-2/h3-13,21,27H,1-2H3,(H,26,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.08E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145761
PNG
((S)-1-(2,4-Dichloro-phenylamino)-4-pyridin-4-yl-1-...)
Show SMILES Cc1ccccc1[C@H](Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C22H20Cl2N2O/c1-15-4-2-3-5-18(15)22(26-20-8-7-17(23)14-19(20)24)21(27)9-6-16-10-12-25-13-11-16/h2-5,7-8,10-14,22,26H,6,9H2,1H3/t22-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.18E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145728
PNG
(1-(2-Chloro-4-methyl-phenylamino)-1-(2-isopropyl-p...)
Show SMILES CC(C)c1ccccc1C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C25H27ClN2O/c1-17(2)20-6-4-5-7-21(20)25(28-23-10-8-18(3)16-22(23)26)24(29)11-9-19-12-14-27-15-13-19/h4-8,10,12-17,25,28H,9,11H2,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.30E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145752
PNG
(1-(2-Chloro-4-methyl-phenylamino)-1-(2-chloro-phen...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2Cl)c(Cl)c1
Show InChI InChI=1S/C22H20Cl2N2O/c1-15-6-8-20(19(24)14-15)26-22(17-4-2-3-5-18(17)23)21(27)9-7-16-10-12-25-13-11-16/h2-6,8,10-14,22,26H,7,9H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.35E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity of compound towards human Corticotropin releasing factor receptor 1


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145753
PNG
(1-(2-Chloro-4-methyl-phenylamino)-1-(3-chloro-phen...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2cccc(Cl)c2)c(Cl)c1
Show InChI InChI=1S/C22H20Cl2N2O/c1-15-5-7-20(19(24)13-15)26-22(17-3-2-4-18(23)14-17)21(27)8-6-16-9-11-25-12-10-16/h2-5,7,9-14,22,26H,6,8H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>5.00E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145763
PNG
(1-(2-Bromo-phenyl)-1-(2-chloro-phenylamino)-4-pyri...)
Show SMILES Clc1ccccc1NC(C(=O)CCc1ccncc1)c1ccccc1Br
Show InChI InChI=1S/C21H18BrClN2O/c22-17-6-2-1-5-16(17)21(25-19-8-4-3-7-18(19)23)20(26)10-9-15-11-13-24-14-12-15/h1-8,11-14,21,25H,9-10H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
7.33E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145765
PNG
(1-(2-Chloro-4-methyl-phenylamino)-1-phenyl-4-pyrid...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2)c(Cl)c1
Show InChI InChI=1S/C22H21ClN2O/c1-16-7-9-20(19(23)15-16)25-22(18-5-3-2-4-6-18)21(26)10-8-17-11-13-24-14-12-17/h2-7,9,11-15,22,25H,8,10H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145766
PNG
(1-(2-Chloro-4-methyl-phenylamino)-1-(4-chloro-phen...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccc(Cl)cc2)c(Cl)c1
Show InChI InChI=1S/C22H20Cl2N2O/c1-15-2-8-20(19(24)14-15)26-22(17-4-6-18(23)7-5-17)21(27)9-3-16-10-12-25-13-11-16/h2,4-8,10-14,22,26H,3,9H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145760
PNG
(1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...)
Show SMILES Cc1ccc(NC(C(=O)CCc2cccnc2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C22H20BrClN2O/c1-15-8-10-20(19(24)13-15)26-22(17-6-2-3-7-18(17)23)21(27)11-9-16-5-4-12-25-14-16/h2-8,10,12-14,22,26H,9,11H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145756
PNG
(1-(2-Chloro-4-methyl-phenylamino)-1-(2,6-dimethoxy...)
Show SMILES COc1cccc(OC)c1C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C24H25ClN2O3/c1-16-7-9-19(18(25)15-16)27-24(20(28)10-8-17-11-13-26-14-12-17)23-21(29-2)5-4-6-22(23)30-3/h4-7,9,11-15,24,27H,8,10H2,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145757
PNG
(1-(2-Chloro-4-methyl-phenylamino)-4-pyridin-4-yl-1...)
Show SMILES Cc1ccc(cc1)C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C23H23ClN2O/c1-16-3-7-19(8-4-16)23(26-21-9-5-17(2)15-20(21)24)22(27)10-6-18-11-13-25-14-12-18/h3-5,7-9,11-15,23,26H,6,10H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145762
PNG
(1-(2-Chloro-4-methyl-phenylamino)-1-(2,4-dimethoxy...)
Show SMILES COc1ccc(C(Nc2ccc(C)cc2Cl)C(=O)CCc2ccncc2)c(OC)c1
Show InChI InChI=1S/C24H25ClN2O3/c1-16-4-8-21(20(25)14-16)27-24(19-7-6-18(29-2)15-23(19)30-3)22(28)9-5-17-10-12-26-13-11-17/h4,6-8,10-15,24,27H,5,9H2,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145750
PNG
(1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...)
Show SMILES Cc1ccc(NC(C(=O)Cc2ccncc2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C21H18BrClN2O/c1-14-6-7-19(18(23)12-14)25-21(16-4-2-3-5-17(16)22)20(26)13-15-8-10-24-11-9-15/h2-12,21,25H,13H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145747
PNG
(2-(2,4-Dichloro-phenylamino)-1-(3,4-dimethoxy-phen...)
Show SMILES COc1ccc(cc1OC)C(=O)C(Nc1ccc(Cl)cc1Cl)c1ccccc1C
Show InChI InChI=1S/C23H21Cl2NO3/c1-14-6-4-5-7-17(14)22(26-19-10-9-16(24)13-18(19)25)23(27)15-8-11-20(28-2)21(12-15)29-3/h4-13,22,26H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145746
PNG
(1-(2-Chloro-4-methyl-phenylamino)-4-pyridin-4-yl-1...)
Show SMILES Cc1cccc(c1)C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C23H23ClN2O/c1-16-4-3-5-19(14-16)23(26-21-8-6-17(2)15-20(21)24)22(27)9-7-18-10-12-25-13-11-18/h3-6,8,10-15,23,26H,7,9H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145748
PNG
(1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...)
Show SMILES Cc1ccc(NC(C(=O)CCc2cnc[nH]2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C20H19BrClN3O/c1-13-6-8-18(17(22)10-13)25-20(15-4-2-3-5-16(15)21)19(26)9-7-14-11-23-12-24-14/h2-6,8,10-12,20,25H,7,9H2,1H3,(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145744
PNG
(1-(2-Chloro-4-methyl-phenylamino)-1-(3-methoxy-phe...)
Show SMILES COc1cccc(c1)C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C23H23ClN2O2/c1-16-6-8-21(20(24)14-16)26-23(18-4-3-5-19(15-18)28-2)22(27)9-7-17-10-12-25-13-11-17/h3-6,8,10-15,23,26H,7,9H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145743
PNG
(1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccccc2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C23H21BrClNO/c1-16-11-13-21(20(25)15-16)26-23(18-9-5-6-10-19(18)24)22(27)14-12-17-7-3-2-4-8-17/h2-11,13,15,23,26H,12,14H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145738
PNG
(1-(2-Chloro-4-methyl-phenylamino)-1-(2-methoxy-phe...)
Show SMILES COc1ccccc1C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C23H23ClN2O2/c1-16-7-9-20(19(24)15-16)26-23(18-5-3-4-6-22(18)28-2)21(27)10-8-17-11-13-25-14-12-17/h3-7,9,11-15,23,26H,8,10H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145736
PNG
(1-(2-Chloro-4-methyl-phenylamino)-1-(2-fluoro-phen...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2F)c(Cl)c1
Show InChI InChI=1S/C22H20ClFN2O/c1-15-6-8-20(18(23)14-15)26-22(17-4-2-3-5-19(17)24)21(27)9-7-16-10-12-25-13-11-16/h2-6,8,10-14,22,26H,7,9H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity of compound towards human Corticotropin releasing factor receptor 1


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145734
PNG
(1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccc(F)cc2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C23H20BrClFNO/c1-15-6-12-21(20(25)14-15)27-23(18-4-2-3-5-19(18)24)22(28)13-9-16-7-10-17(26)11-8-16/h2-8,10-12,14,23,27H,9,13H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145727
PNG
(2-(2,4-Dichloro-phenylamino)-1-(3-hydroxy-phenyl)-...)
Show SMILES Cc1ccccc1C(Nc1ccc(Cl)cc1Cl)C(=O)c1cccc(O)c1
Show InChI InChI=1S/C21H17Cl2NO2/c1-13-5-2-3-8-17(13)20(21(26)14-6-4-7-16(25)11-14)24-19-10-9-15(22)12-18(19)23/h2-12,20,24-25H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145726
PNG
(1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...)
Show SMILES Cc1ccc(NC(C(=O)CCc2ccccn2)c2ccccc2Br)c(Cl)c1
Show InChI InChI=1S/C22H20BrClN2O/c1-15-9-11-20(19(24)14-15)26-22(17-7-2-3-8-18(17)23)21(27)12-10-16-6-4-5-13-25-16/h2-9,11,13-14,22,26H,10,12H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145724
PNG
(1-(2-Bromo-phenyl)-1-[(2-chloro-phenyl)-methyl-ami...)
Show SMILES CN(C(C(=O)CCc1ccncc1)c1ccccc1Br)c1ccccc1Cl
Show InChI InChI=1S/C22H20BrClN2O/c1-26(20-9-5-4-8-19(20)24)22(17-6-2-3-7-18(17)23)21(27)11-10-16-12-14-25-15-13-16/h2-9,12-15,22H,10-11H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50145725
PNG
(1-(2-Chloro-4-methyl-phenylamino)-1-(2,5-dimethoxy...)
Show SMILES COc1ccc(OC)c(c1)C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1
Show InChI InChI=1S/C24H25ClN2O3/c1-16-4-7-21(20(25)14-16)27-24(19-15-18(29-2)6-9-23(19)30-3)22(28)8-5-17-10-12-26-13-11-17/h4,6-7,9-15,24,27H,5,8H2,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharma Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor


J Med Chem 47: 2426-9 (2004)


Article DOI: 10.1021/jm049974i
BindingDB Entry DOI: 10.7270/Q2PZ5888
More data for this
Ligand-Target Pair