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Compile Data Set for Download or QSAR

Found 28 hits from CNRS UMR-8113   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM13530
PNG
(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1
Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)
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n/an/a 100n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174413
PNG
(2-(2-Diethylamino-ethyl)-9-hydroxy-5,11-dimethyl-6...)
Show SMILES CCN(CC)CCn1ccc2c(C)c3[nH+]c4ccc(O)cc4c3c(C)c2c1
Show InChI InChI=1S/C23H27N3O/c1-5-25(6-2)11-12-26-10-9-18-16(4)23-22(15(3)20(18)14-26)19-13-17(27)7-8-21(19)24-23/h7-10,13-14,27H,5-6,11-12H2,1-4H3/p+1
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n/an/a 300n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50004235
PNG
((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...)
Show SMILES Cc1c2[nH+]c3ccc(O)cc3c2c(C)c2cn(C)ccc12
Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1
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n/an/a 400n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM50004227
PNG
(5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...)
Show SMILES Cc1c2[nH]c3ccc(O)cc3c2c(C)c2cnccc12
Show InChI InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3
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n/an/a 400n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory activity against Fibroblast growth factor receptor 3


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50004227
PNG
(5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...)
Show SMILES Cc1c2[nH]c3ccc(O)cc3c2c(C)c2cnccc12
Show InChI InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3
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n/an/a 400n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50004227
PNG
(5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...)
Show SMILES Cc1c2[nH]c3ccc(O)cc3c2c(C)c2cnccc12
Show InChI InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3
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n/an/a 400n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50004235
PNG
((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...)
Show SMILES Cc1c2[nH+]c3ccc(O)cc3c2c(C)c2cn(C)ccc12
Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1
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n/an/a 400n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174413
PNG
(2-(2-Diethylamino-ethyl)-9-hydroxy-5,11-dimethyl-6...)
Show SMILES CCN(CC)CCn1ccc2c(C)c3[nH+]c4ccc(O)cc4c3c(C)c2c1
Show InChI InChI=1S/C23H27N3O/c1-5-25(6-2)11-12-26-10-9-18-16(4)23-22(15(3)20(18)14-26)19-13-17(27)7-8-21(19)24-23/h7-10,13-14,27H,5-6,11-12H2,1-4H3/p+1
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n/an/a 450n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM50004235
PNG
((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...)
Show SMILES Cc1c2[nH+]c3ccc(O)cc3c2c(C)c2cn(C)ccc12
Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1
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n/an/a 500n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory activity against Fibroblast growth factor receptor 3


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174412
PNG
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)
Show SMILES COc1ccc2[nH]c3c(C)c4ccncc4c(C)c3c2c1
Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3
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n/an/a 600n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor


(Homo sapiens (Human))
BDBM50004227
PNG
(5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...)
Show SMILES Cc1c2[nH]c3ccc(O)cc3c2c(C)c2cnccc12
Show InChI InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3
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n/an/a 600n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory activity against Platelet-derived growth factor receptor alpha


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor


(Homo sapiens (Human))
BDBM50004235
PNG
((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...)
Show SMILES Cc1c2[nH+]c3ccc(O)cc3c2c(C)c2cn(C)ccc12
Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1
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n/an/a 700n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory activity against Platelet-derived growth factor receptor alpha


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174412
PNG
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)
Show SMILES COc1ccc2[nH]c3c(C)c4ccncc4c(C)c3c2c1
Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3
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n/an/a 800n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174410
PNG
(1-(3-Diethylamino-propylamino)-5,11-dimethyl-6H-py...)
Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ccc(O)cc4c3c(C)c12
Show InChI InChI=1S/C24H30N4O/c1-5-28(6-2)13-7-11-25-24-22-16(4)21-19-14-17(29)8-9-20(19)27-23(21)15(3)18(22)10-12-26-24/h8-10,12,14,27,29H,5-7,11,13H2,1-4H3,(H,25,26)
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n/an/a 1.20E+3n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174410
PNG
(1-(3-Diethylamino-propylamino)-5,11-dimethyl-6H-py...)
Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ccc(O)cc4c3c(C)c12
Show InChI InChI=1S/C24H30N4O/c1-5-28(6-2)13-7-11-25-24-22-16(4)21-19-14-17(29)8-9-20(19)27-23(21)15(3)18(22)10-12-26-24/h8-10,12,14,27,29H,5-7,11,13H2,1-4H3,(H,25,26)
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n/an/a 1.40E+3n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM50174408
PNG
(1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...)
Show SMILES CCN(CC)CCCNc1nccc2c(C)c3n(C)c4ccc(O)cc4c3c(C)c12
Show InChI InChI=1S/C25H32N4O/c1-6-29(7-2)14-8-12-26-25-23-17(4)22-20-15-18(30)9-10-21(20)28(5)24(22)16(3)19(23)11-13-27-25/h9-11,13,15,30H,6-8,12,14H2,1-5H3,(H,26,27)
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n/an/a 1.40E+3n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory activity against Fibroblast growth factor receptor 3


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174411
PNG
(CHEMBL197610 | N,N-Diethyl-N'-(10-methyl-11H-pyrid...)
Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ncccc4c3cc12
Show InChI InChI=1S/C22H27N5/c1-4-27(5-2)13-7-11-23-21-19-14-18-17-8-6-10-24-22(17)26-20(18)15(3)16(19)9-12-25-21/h6,8-10,12,14H,4-5,7,11,13H2,1-3H3,(H,23,25)(H,24,26)
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n/an/a 1.90E+3n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor


(Homo sapiens (Human))
BDBM50174408
PNG
(1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...)
Show SMILES CCN(CC)CCCNc1nccc2c(C)c3n(C)c4ccc(O)cc4c3c(C)c12
Show InChI InChI=1S/C25H32N4O/c1-6-29(7-2)14-8-12-26-25-23-17(4)22-20-15-18(30)9-10-21(20)28(5)24(22)16(3)19(23)11-13-27-25/h9-11,13,15,30H,6-8,12,14H2,1-5H3,(H,26,27)
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n/an/a 2.00E+3n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory activity against Platelet-derived growth factor receptor alpha


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174407
PNG
(CHEMBL279472 | N,N-Diethyl-N'-(9-methoxy-5-methyl-...)
Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ccc(OC)cc4c3cc12
Show InChI InChI=1S/C24H30N4O/c1-5-28(6-2)13-7-11-25-24-21-15-20-19-14-17(29-4)8-9-22(19)27-23(20)16(3)18(21)10-12-26-24/h8-10,12,14-15,27H,5-7,11,13H2,1-4H3,(H,25,26)
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n/an/a 2.00E+3n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174411
PNG
(CHEMBL197610 | N,N-Diethyl-N'-(10-methyl-11H-pyrid...)
Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ncccc4c3cc12
Show InChI InChI=1S/C22H27N5/c1-4-27(5-2)13-7-11-23-21-19-14-18-17-8-6-10-24-22(17)26-20(18)15(3)16(19)9-12-25-21/h6,8-10,12,14H,4-5,7,11,13H2,1-3H3,(H,23,25)(H,24,26)
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n/an/a 2.30E+3n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174407
PNG
(CHEMBL279472 | N,N-Diethyl-N'-(9-methoxy-5-methyl-...)
Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ccc(OC)cc4c3cc12
Show InChI InChI=1S/C24H30N4O/c1-5-28(6-2)13-7-11-25-24-21-15-20-19-14-17(29-4)8-9-22(19)27-23(20)16(3)18(21)10-12-26-24/h8-10,12,14-15,27H,5-7,11,13H2,1-4H3,(H,25,26)
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n/an/a 2.50E+3n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174408
PNG
(1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...)
Show SMILES CCN(CC)CCCNc1nccc2c(C)c3n(C)c4ccc(O)cc4c3c(C)c12
Show InChI InChI=1S/C25H32N4O/c1-6-29(7-2)14-8-12-26-25-23-17(4)22-20-15-18(30)9-10-21(20)28(5)24(22)16(3)19(23)11-13-27-25/h9-11,13,15,30H,6-8,12,14H2,1-5H3,(H,26,27)
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n/an/a 2.50E+3n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174408
PNG
(1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...)
Show SMILES CCN(CC)CCCNc1nccc2c(C)c3n(C)c4ccc(O)cc4c3c(C)c12
Show InChI InChI=1S/C25H32N4O/c1-6-29(7-2)14-8-12-26-25-23-17(4)22-20-15-18(30)9-10-21(20)28(5)24(22)16(3)19(23)11-13-27-25/h9-11,13,15,30H,6-8,12,14H2,1-5H3,(H,26,27)
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n/an/a 3.60E+3n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50004233
PNG
(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Show SMILES Cc1c2[nH]c3ccccc3c2c(C)c2cnccc12
Show InChI InChI=1S/C17H14N2/c1-10-14-9-18-8-7-12(14)11(2)17-16(10)13-5-3-4-6-15(13)19-17/h3-9,19H,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174409
PNG
(9-Bromo-5,11-dimethyl-6H-pyrido[4,3-b]carbazole | ...)
Show SMILES Cc1c2[nH]c3ccc(Br)cc3c2c(C)c2cnccc12
Show InChI InChI=1S/C17H13BrN2/c1-9-14-8-19-6-5-12(14)10(2)17-16(9)13-7-11(18)3-4-15(13)20-17/h3-8,20H,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50004233
PNG
(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)
Show SMILES Cc1c2[nH]c3ccccc3c2c(C)c2cnccc12
Show InChI InChI=1S/C17H14N2/c1-10-14-9-18-8-7-12(14)11(2)17-16(10)13-5-3-4-6-15(13)19-17/h3-9,19H,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50174409
PNG
(9-Bromo-5,11-dimethyl-6H-pyrido[4,3-b]carbazole | ...)
Show SMILES Cc1c2[nH]c3ccc(Br)cc3c2c(C)c2cnccc12
Show InChI InChI=1S/C17H13BrN2/c1-9-14-8-19-6-5-12(14)10(2)17-16(9)13-7-11(18)3-4-15(13)20-17/h3-8,20H,1-2H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM13530
PNG
(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1
Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)
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n/an/a 1.00E+4n/an/an/an/an/an/a



CNRS UMR-8113

Curated by ChEMBL


Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus


J Med Chem 48: 6194-201 (2005)


Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR
More data for this
Ligand-Target Pair