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Compile Data Set for Download or QSAR

Found 129 hits from CSIR-Indian Institute of Chemical Biology   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lipoxygenase (SLO)


(Glycine max (Soybean))
BDBM222272
PNG
(5-(4-Bromo-phenyl)-4[2-(4-bromo-phenyl)-2-oxo-ethy...)
Show SMILES COC(=O)c1c(C)oc(c1CC(=O)c1ccc(Br)cc1)-c1ccc(Br)cc1
Show InChI InChI=1S/C21H16Br2O4/c1-12-19(21(25)26-2)17(11-18(24)13-3-7-15(22)8-4-13)20(27-12)14-5-9-16(23)10-6-14/h3-10H,11H2,1-2H3
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70.9n/an/an/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology



Assay Description
The crystal structure of soybean lipoxygenase-1 (PDB code: 3PZW), was used in our docking experiments. The 3D structure of 3PZW was reported by Chrus...


Bioorg Chem 71: 97-101 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.016
BindingDB Entry DOI: 10.7270/Q2F76BCD
More data for this
Ligand-Target Pair
Lipoxygenase (SLO)


(Glycine max (Soybean))
BDBM222273
PNG
(5-(4-Bromo-phenyl)-4[2-(4-bromo-phenyl)-2-oxo-ethy...)
Show SMILES CCOC(=O)c1c(C)oc(c1CC(=O)c1ccc(Br)cc1)-c1ccc(Br)cc1
Show InChI InChI=1S/C22H18Br2O4/c1-3-27-22(26)20-13(2)28-21(15-6-10-17(24)11-7-15)18(20)12-19(25)14-4-8-16(23)9-5-14/h4-11H,3,12H2,1-2H3
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141n/an/an/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology



Assay Description
The crystal structure of soybean lipoxygenase-1 (PDB code: 3PZW), was used in our docking experiments. The 3D structure of 3PZW was reported by Chrus...


Bioorg Chem 71: 97-101 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.016
BindingDB Entry DOI: 10.7270/Q2F76BCD
More data for this
Ligand-Target Pair
Lipoxygenase (SLO)


(Glycine max (Soybean))
BDBM222270
PNG
(Methyl 2-methyl-5-(4-methylphenyl)-4-[2-(4-methylp...)
Show SMILES COC(=O)c1c(C)oc(c1CC(=O)c1ccc(C)cc1)-c1ccc(C)cc1
Show InChI InChI=1S/C23H22O4/c1-14-5-9-17(10-6-14)20(24)13-19-21(23(25)26-4)16(3)27-22(19)18-11-7-15(2)8-12-18/h5-12H,13H2,1-4H3
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179n/an/an/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology



Assay Description
The crystal structure of soybean lipoxygenase-1 (PDB code: 3PZW), was used in our docking experiments. The 3D structure of 3PZW was reported by Chrus...


Bioorg Chem 71: 97-101 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.016
BindingDB Entry DOI: 10.7270/Q2F76BCD
More data for this
Ligand-Target Pair
Lipoxygenase (SLO)


(Glycine max (Soybean))
BDBM32020
PNG
(4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...)
Show SMILES CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1
Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3
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232n/an/an/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology



Assay Description
The crystal structure of soybean lipoxygenase-1 (PDB code: 3PZW), was used in our docking experiments. The 3D structure of 3PZW was reported by Chrus...


Bioorg Chem 71: 97-101 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.016
BindingDB Entry DOI: 10.7270/Q2F76BCD
More data for this
Ligand-Target Pair
Lipoxygenase (SLO)


(Glycine max (Soybean))
BDBM222271
PNG
(2-Methyl-4-(2-oxo-2-p-tolyl-ethyl)-5-p-tolyl-furan...)
Show SMILES CCOC(=O)c1c(C)oc(c1CC(=O)c1ccc(C)cc1)-c1ccc(C)cc1
Show InChI InChI=1S/C24H24O4/c1-5-27-24(26)22-17(4)28-23(19-12-8-16(3)9-13-19)20(22)14-21(25)18-10-6-15(2)7-11-18/h6-13H,5,14H2,1-4H3
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246n/an/an/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology



Assay Description
The crystal structure of soybean lipoxygenase-1 (PDB code: 3PZW), was used in our docking experiments. The 3D structure of 3PZW was reported by Chrus...


Bioorg Chem 71: 97-101 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.016
BindingDB Entry DOI: 10.7270/Q2F76BCD
More data for this
Ligand-Target Pair
Lipoxygenase (SLO)


(Glycine max (Soybean))
BDBM222274
PNG
(5-(4-Chloro-phenyl)-4[2-(4-chloro-phenyl)-2-oxo-et...)
Show SMILES COC(=O)c1c(C)oc(c1CC(=O)c1ccc(Cl)cc1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H16Cl2O4/c1-12-19(21(25)26-2)17(11-18(24)13-3-7-15(22)8-4-13)20(27-12)14-5-9-16(23)10-6-14/h3-10H,11H2,1-2H3
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313n/an/an/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology



Assay Description
The crystal structure of soybean lipoxygenase-1 (PDB code: 3PZW), was used in our docking experiments. The 3D structure of 3PZW was reported by Chrus...


Bioorg Chem 71: 97-101 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.016
BindingDB Entry DOI: 10.7270/Q2F76BCD
More data for this
Ligand-Target Pair
Lipoxygenase (SLO)


(Glycine max (Soybean))
BDBM222275
PNG
(5-(4-Chloro-phenyl)-4[2-(4-chloro-phenyl)-2-oxo-et...)
Show SMILES CCOC(=O)c1c(C)oc(c1CC(=O)c1ccc(Cl)cc1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C22H18Cl2O4/c1-3-27-22(26)20-13(2)28-21(15-6-10-17(24)11-7-15)18(20)12-19(25)14-4-8-16(23)9-5-14/h4-11H,3,12H2,1-2H3
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345n/an/an/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology



Assay Description
The crystal structure of soybean lipoxygenase-1 (PDB code: 3PZW), was used in our docking experiments. The 3D structure of 3PZW was reported by Chrus...


Bioorg Chem 71: 97-101 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.016
BindingDB Entry DOI: 10.7270/Q2F76BCD
More data for this
Ligand-Target Pair
Lipoxygenase (SLO)


(Glycine max (Soybean))
BDBM222277
PNG
(5-(3-Chloro-4-methyl-phenyl)-4-[2-(3-chloro-4-meth...)
Show SMILES COC(=O)c1c(C)oc(c1CC(=O)c1ccc(C)c(Cl)c1)-c1ccc(C)c(Cl)c1
Show InChI InChI=1S/C23H20Cl2O4/c1-12-5-7-15(9-18(12)24)20(26)11-17-21(23(27)28-4)14(3)29-22(17)16-8-6-13(2)19(25)10-16/h5-10H,11H2,1-4H3
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357n/an/an/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology



Assay Description
The crystal structure of soybean lipoxygenase-1 (PDB code: 3PZW), was used in our docking experiments. The 3D structure of 3PZW was reported by Chrus...


Bioorg Chem 71: 97-101 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.016
BindingDB Entry DOI: 10.7270/Q2F76BCD
More data for this
Ligand-Target Pair
Lipoxygenase (SLO)


(Glycine max (Soybean))
BDBM222276
PNG
(5-(3-Chloro-4-methyl-phenyl)-4-[2-(3-chloro-4-meth...)
Show SMILES CCOC(=O)c1c(C)oc(c1CC(=O)c1ccc(C)c(Cl)c1)-c1ccc(C)c(Cl)c1
Show InChI InChI=1S/C24H22Cl2O4/c1-5-29-24(28)22-15(4)30-23(17-9-7-14(3)20(26)11-17)18(22)12-21(27)16-8-6-13(2)19(25)10-16/h6-11H,5,12H2,1-4H3
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539n/an/an/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology



Assay Description
The crystal structure of soybean lipoxygenase-1 (PDB code: 3PZW), was used in our docking experiments. The 3D structure of 3PZW was reported by Chrus...


Bioorg Chem 71: 97-101 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.016
BindingDB Entry DOI: 10.7270/Q2F76BCD
More data for this
Ligand-Target Pair
Lipoxygenase (SLO)


(Glycine max (Soybean))
BDBM222268
PNG
(2-Methyl-4-(2-oxo-2-phenyl-ethyl)-5-phenyl-furan-3...)
Show SMILES COC(=O)c1c(C)oc(c1CC(=O)c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C21H18O4/c1-14-19(21(23)24-2)17(13-18(22)15-9-5-3-6-10-15)20(25-14)16-11-7-4-8-12-16/h3-12H,13H2,1-2H3
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662n/an/an/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology



Assay Description
The crystal structure of soybean lipoxygenase-1 (PDB code: 3PZW), was used in our docking experiments. The 3D structure of 3PZW was reported by Chrus...


Bioorg Chem 71: 97-101 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.016
BindingDB Entry DOI: 10.7270/Q2F76BCD
More data for this
Ligand-Target Pair
Lipoxygenase (SLO)


(Glycine max (Soybean))
BDBM222269
PNG
(2-Methyl-4-(2-oxo-2-phenyl-ethyl)-5-phenyl-furan-3...)
Show SMILES CCOC(=O)c1c(C)oc(c1CC(=O)c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C22H20O4/c1-3-25-22(24)20-15(2)26-21(17-12-8-5-9-13-17)18(20)14-19(23)16-10-6-4-7-11-16/h4-13H,3,14H2,1-2H3
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868n/an/an/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology



Assay Description
The crystal structure of soybean lipoxygenase-1 (PDB code: 3PZW), was used in our docking experiments. The 3D structure of 3PZW was reported by Chrus...


Bioorg Chem 71: 97-101 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.016
BindingDB Entry DOI: 10.7270/Q2F76BCD
More data for this
Ligand-Target Pair
Toll-like receptor 3/8/9


(Homo sapiens (Human))
BDBM50252308
PNG
(CHEMBL4065452)
Show SMILES C(COc1ccc(cc1)-c1nc2ccc(OCCCN3CCCC3)cc2o1)CN1CCCC1
Show InChI InChI=1S/C27H35N3O3/c1-2-14-29(13-1)17-5-19-31-23-9-7-22(8-10-23)27-28-25-12-11-24(21-26(25)33-27)32-20-6-18-30-15-3-4-16-30/h7-12,21H,1-6,13-20H2
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n/an/a 15n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Inhibition of recombinant full length Anopheles gambiae AChE1 expressed in baculovirus-infected Sf9 insect cells using acetylthiocholine iodide as su...


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467784
PNG
(CHEMBL4278635)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N(C)C)N1CCN(CC1)C(=O)c1ccccc1
Show InChI InChI=1S/C29H38N6O3/c1-32(2)29-30-24-21-26(38-19-9-14-33-12-7-8-13-33)25(37-3)20-23(24)27(31-29)34-15-17-35(18-16-34)28(36)22-10-5-4-6-11-22/h4-6,10-11,20-21H,7-9,12-19H2,1-3H3
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n/an/a 20n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467770
PNG
(CHEMBL4279467)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N(C)C)N1CCNCC1
Show InChI InChI=1S/C22H34N6O2/c1-26(2)22-24-18-16-20(30-14-6-11-27-9-4-5-10-27)19(29-3)15-17(18)21(25-22)28-12-7-23-8-13-28/h15-16,23H,4-14H2,1-3H3
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n/an/a 20n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467773
PNG
(CHEMBL4282131)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N1CCN(C)CC1)N1CCN(CC1)C1CCCC1
Show InChI InChI=1S/C30H47N7O2/c1-33-13-15-37(16-14-33)30-31-26-23-28(39-21-7-12-34-10-5-6-11-34)27(38-2)22-25(26)29(32-30)36-19-17-35(18-20-36)24-8-3-4-9-24/h22-24H,3-21H2,1-2H3
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n/an/a 20n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467766
PNG
(CHEMBL4276673)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N(C)C)N1CCN(CC1)C1CCCC1
Show InChI InChI=1S/C27H42N6O2/c1-30(2)27-28-23-20-25(35-18-8-13-31-11-6-7-12-31)24(34-3)19-22(23)26(29-27)33-16-14-32(15-17-33)21-9-4-5-10-21/h19-21H,4-18H2,1-3H3
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n/an/a 20n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467794
PNG
(CHEMBL4290314)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N(C)C)N1CCN(CC1)C(=O)c1ccc(CN)cc1
Show InChI InChI=1S/C30H41N7O3/c1-34(2)30-32-25-20-27(40-18-6-13-35-11-4-5-12-35)26(39-3)19-24(25)28(33-30)36-14-16-37(17-15-36)29(38)23-9-7-22(21-31)8-10-23/h7-10,19-20H,4-6,11-18,21,31H2,1-3H3
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n/an/a 30n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467782
PNG
(CHEMBL4279648)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N(C)C)N1CCN(CC1)C(=O)c1ccc(F)cc1
Show InChI InChI=1S/C29H37FN6O3/c1-33(2)29-31-24-20-26(39-18-6-13-34-11-4-5-12-34)25(38-3)19-23(24)27(32-29)35-14-16-36(17-15-35)28(37)21-7-9-22(30)10-8-21/h7-10,19-20H,4-6,11-18H2,1-3H3
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n/an/a 30n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467775
PNG
(CHEMBL4278682)
Show SMILES COc1cc2c(nc(NCCCN3CCN(C)CC3)nc2cc1OCCCN1CCCC1)N1CCN(CC1)C1CCCC1
Show InChI InChI=1S/C33H54N8O2/c1-37-16-18-39(19-17-37)14-7-11-34-33-35-29-26-31(43-24-8-15-38-12-5-6-13-38)30(42-2)25-28(29)32(36-33)41-22-20-40(21-23-41)27-9-3-4-10-27/h25-27H,3-24H2,1-2H3,(H,34,35,36)
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n/an/a 30n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467774
PNG
(CHEMBL4286933)
Show SMILES COc1cc2c(nc(NCCCN3CCN(C)CC3)nc2cc1OCCCN1CCCC1)N1CCN(C)CC1
Show InChI InChI=1S/C29H48N8O2/c1-33-13-17-36(18-14-33)11-6-8-30-29-31-25-23-27(39-21-7-12-35-9-4-5-10-35)26(38-3)22-24(25)28(32-29)37-19-15-34(2)16-20-37/h22-23H,4-21H2,1-3H3,(H,30,31,32)
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n/an/a 30n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467786
PNG
(CHEMBL4281194)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N(C)C)N1CCN(CC2CCCC2)CC1
Show InChI InChI=1S/C28H44N6O2/c1-31(2)28-29-24-20-26(36-18-8-13-32-11-6-7-12-32)25(35-3)19-23(24)27(30-28)34-16-14-33(15-17-34)21-22-9-4-5-10-22/h19-20,22H,4-18,21H2,1-3H3
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n/an/a 30n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50252307
PNG
(CHEMBL4082132)
Show SMILES CN1CCC(CC1)Nc1cccc(c1)-c1nc2ccc(OCCCN3CCCC3)cc2o1
Show InChI InChI=1S/C26H34N4O2/c1-29-15-10-21(11-16-29)27-22-7-4-6-20(18-22)26-28-24-9-8-23(19-25(24)32-26)31-17-5-14-30-12-2-3-13-30/h4,6-9,18-19,21,27H,2-3,5,10-17H2,1H3
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n/an/a 37n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK293 cells assessed as inhibition of CpGB-induced NF-kappaB activation after 24 hrs by spectrophotom...


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467772
PNG
(CHEMBL4284496)
Show SMILES COc1cc2c(nc(NCc3ccc(F)cc3)nc2cc1OCCCN1CCCC1)N1CCN(CC1)C1CCCC1
Show InChI InChI=1S/C32H43FN6O2/c1-40-29-21-27-28(22-30(29)41-20-6-15-37-13-4-5-14-37)35-32(34-23-24-9-11-25(33)12-10-24)36-31(27)39-18-16-38(17-19-39)26-7-2-3-8-26/h9-12,21-22,26H,2-8,13-20,23H2,1H3,(H,34,35,36)
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n/an/a 40n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467787
PNG
(CHEMBL4284607)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N(C)C)N1CCN(C)CC1
Show InChI InChI=1S/C23H36N6O2/c1-26(2)23-24-19-17-21(31-15-7-10-28-8-5-6-9-28)20(30-4)16-18(19)22(25-23)29-13-11-27(3)12-14-29/h16-17H,5-15H2,1-4H3
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n/an/a 40n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 3/8/9


(Homo sapiens (Human))
BDBM50252309
PNG
(CHEMBL4100657)
Show SMILES CN(C)Cc1ccc(cc1)C(=O)Nc1cccc(c1)-c1nc2ccc(OCCCN3CCCC3)cc2o1
Show InChI InChI=1S/C30H34N4O3/c1-33(2)21-22-9-11-23(12-10-22)29(35)31-25-8-5-7-24(19-25)30-32-27-14-13-26(20-28(27)37-30)36-18-6-17-34-15-3-4-16-34/h5,7-14,19-20H,3-4,6,15-18,21H2,1-2H3,(H,31,35)
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n/an/a 48n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at TLR9 in human PBMC assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50252309
PNG
(CHEMBL4100657)
Show SMILES CN(C)Cc1ccc(cc1)C(=O)Nc1cccc(c1)-c1nc2ccc(OCCCN3CCCC3)cc2o1
Show InChI InChI=1S/C30H34N4O3/c1-33(2)21-22-9-11-23(12-10-22)29(35)31-25-8-5-7-24(19-25)30-32-27-14-13-26(20-28(27)37-30)36-18-6-17-34-15-3-4-16-34/h5,7-14,19-20H,3-4,6,15-18,21H2,1-2H3,(H,31,35)
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n/an/a<50n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at TLR9 in human plasmacytoid dendritic cells assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50252308
PNG
(CHEMBL4065452)
Show SMILES C(COc1ccc(cc1)-c1nc2ccc(OCCCN3CCCC3)cc2o1)CN1CCCC1
Show InChI InChI=1S/C27H35N3O3/c1-2-14-29(13-1)17-5-19-31-23-9-7-22(8-10-23)27-28-25-12-11-24(21-26(25)33-27)32-20-6-18-30-15-3-4-16-30/h7-12,21H,1-6,13-20H2
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n/an/a<50n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at TLR9 in human plasmacytoid dendritic cells assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467796
PNG
(CHEMBL4285558)
Show SMILES COc1cc2c(nc(NCCCn3ccnc3)nc2cc1OCCCN1CCCC1)N1CCN(CC1)C1CCCC1
Show InChI InChI=1S/C31H46N8O2/c1-40-28-22-26-27(23-29(28)41-21-7-15-36-12-4-5-13-36)34-31(33-10-6-14-37-16-11-32-24-37)35-30(26)39-19-17-38(18-20-39)25-8-2-3-9-25/h11,16,22-25H,2-10,12-15,17-21H2,1H3,(H,33,34,35)
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n/an/a 50n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 3/8/9


(Homo sapiens (Human))
BDBM50252309
PNG
(CHEMBL4100657)
Show SMILES CN(C)Cc1ccc(cc1)C(=O)Nc1cccc(c1)-c1nc2ccc(OCCCN3CCCC3)cc2o1
Show InChI InChI=1S/C30H34N4O3/c1-33(2)21-22-9-11-23(12-10-22)29(35)31-25-8-5-7-24(19-25)30-32-27-14-13-26(20-28(27)37-30)36-18-6-17-34-15-3-4-16-34/h5,7-14,19-20H,3-4,6,15-18,21H2,1-2H3,(H,31,35)
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n/an/a<50n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at TLR9 in human PBMC assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467778
PNG
(CHEMBL4280997)
Show SMILES COc1cc2c(nc(nc2cc1OC1CCCC1)N(C)C)N1CCN(C)CC1
Show InChI InChI=1S/C21H31N5O2/c1-24(2)21-22-17-14-19(28-15-7-5-6-8-15)18(27-4)13-16(17)20(23-21)26-11-9-25(3)10-12-26/h13-15H,5-12H2,1-4H3
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n/an/a 50n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 3/8/9


(Homo sapiens (Human))
BDBM50252307
PNG
(CHEMBL4082132)
Show SMILES CN1CCC(CC1)Nc1cccc(c1)-c1nc2ccc(OCCCN3CCCC3)cc2o1
Show InChI InChI=1S/C26H34N4O2/c1-29-15-10-21(11-16-29)27-22-7-4-6-20(18-22)26-28-24-9-8-23(19-25(24)32-26)31-17-5-14-30-12-2-3-13-30/h4,6-9,18-19,21,27H,2-3,5,10-17H2,1H3
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n/an/a<50n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK293 cells assessed as inhibition of CpGB-induced NF-kappaB activation after 24 hrs by spectrophotom...


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 3/8/9


(Homo sapiens (Human))
BDBM50252308
PNG
(CHEMBL4065452)
Show SMILES C(COc1ccc(cc1)-c1nc2ccc(OCCCN3CCCC3)cc2o1)CN1CCCC1
Show InChI InChI=1S/C27H35N3O3/c1-2-14-29(13-1)17-5-19-31-23-9-7-22(8-10-23)27-28-25-12-11-24(21-26(25)33-27)32-20-6-18-30-15-3-4-16-30/h7-12,21H,1-6,13-20H2
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n/an/a<50n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at TLR9 in human PBMC assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 3/8/9


(Homo sapiens (Human))
BDBM50252307
PNG
(CHEMBL4082132)
Show SMILES CN1CCC(CC1)Nc1cccc(c1)-c1nc2ccc(OCCCN3CCCC3)cc2o1
Show InChI InChI=1S/C26H34N4O2/c1-29-15-10-21(11-16-29)27-22-7-4-6-20(18-22)26-28-24-9-8-23(19-25(24)32-26)31-17-5-14-30-12-2-3-13-30/h4,6-9,18-19,21,27H,2-3,5,10-17H2,1H3
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n/an/a<50n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at TLR9 in human PBMC assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50252325
PNG
(CHEMBL4071152)
Show SMILES NC1CCN(CCCOc2ccc(cc2)-c2nc3ccc(OCCCN4CCC(N)C4)cc3o2)C1
Show InChI InChI=1/C27H37N5O3/c28-21-9-13-31(18-21)11-1-15-33-23-5-3-20(4-6-23)27-30-25-8-7-24(17-26(25)35-27)34-16-2-12-32-14-10-22(29)19-32/h3-8,17,21-22H,1-2,9-16,18-19,28-29H2
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n/an/a 60n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK293 cells assessed as inhibition of CpGB-induced NF-kappaB activation after 24 hrs by spectrophotom...


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467771
PNG
(CHEMBL4291815)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N(C)C)N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C29H40N6O2/c1-32(2)29-30-25-21-27(37-19-9-14-33-12-7-8-13-33)26(36-3)20-24(25)28(31-29)35-17-15-34(16-18-35)22-23-10-5-4-6-11-23/h4-6,10-11,20-21H,7-9,12-19,22H2,1-3H3
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n/an/a 80n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50252273
PNG
(CHEMBL4100834)
Show SMILES C(COc1ccc(cc1)-c1nc2ccc(OCCCN3CCCCC3)cc2o1)CN1CCCCC1
Show InChI InChI=1S/C29H39N3O3/c1-3-15-31(16-4-1)19-7-21-33-25-11-9-24(10-12-25)29-30-27-14-13-26(23-28(27)35-29)34-22-8-20-32-17-5-2-6-18-32/h9-14,23H,1-8,15-22H2
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n/an/a 98n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK293 cells assessed as inhibition of CpGB-induced NF-kappaB activation after 24 hrs by spectrophotom...


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 3/8/9


(Homo sapiens (Human))
BDBM50252291
PNG
(CHEMBL4073879)
Show SMILES C(COc1ccc2nc(oc2c1)-c1cccc(c1)C1=CCNCC1)CN1CCCC1
Show InChI InChI=1S/C25H29N3O2/c1-2-14-28(13-1)15-4-16-29-22-7-8-23-24(18-22)30-25(27-23)21-6-3-5-20(17-21)19-9-11-26-12-10-19/h3,5-9,17-18,26H,1-2,4,10-16H2
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n/an/a 99n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at TLR9 in human PBMC assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 3/8/9


(Homo sapiens (Human))
BDBM50252324
PNG
(CHEMBL4100138)
Show SMILES C(COc1ccc2nc(oc2c1)-c1cccc(NC2CCN(Cc3ccccc3)CC2)c1)CN1CCCC1
Show InChI InChI=1S/C32H38N4O2/c1-2-8-25(9-3-1)24-36-19-14-27(15-20-36)33-28-11-6-10-26(22-28)32-34-30-13-12-29(23-31(30)38-32)37-21-7-18-35-16-4-5-17-35/h1-3,6,8-13,22-23,27,33H,4-5,7,14-21,24H2
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n/an/a 100n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at TLR9 in human plasmacytoid dendritic cells assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50252291
PNG
(CHEMBL4073879)
Show SMILES C(COc1ccc2nc(oc2c1)-c1cccc(c1)C1=CCNCC1)CN1CCCC1
Show InChI InChI=1S/C25H29N3O2/c1-2-14-28(13-1)15-4-16-29-22-7-8-23-24(18-22)30-25(27-23)21-6-3-5-20(17-21)19-9-11-26-12-10-19/h3,5-9,17-18,26H,1-2,4,10-16H2
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n/an/a 100n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at TLR9 in human plasmacytoid dendritic cells assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 3/8/9


(Homo sapiens (Human))
BDBM50252291
PNG
(CHEMBL4073879)
Show SMILES C(COc1ccc2nc(oc2c1)-c1cccc(c1)C1=CCNCC1)CN1CCCC1
Show InChI InChI=1S/C25H29N3O2/c1-2-14-28(13-1)15-4-16-29-22-7-8-23-24(18-22)30-25(27-23)21-6-3-5-20(17-21)19-9-11-26-12-10-19/h3,5-9,17-18,26H,1-2,4,10-16H2
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n/an/a 100n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Inhibition of AChE1 in Anopheles gambiae body extract using acetylthiocholine iodide as substrate measured over 60 secs by Ellman's method


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467789
PNG
(CHEMBL4287813)
Show SMILES COc1cc2c(nc(nc2cc1OC1CCCC1)N(C)C)N1CCNCC1
Show InChI InChI=1S/C20H29N5O2/c1-24(2)20-22-16-13-18(27-14-6-4-5-7-14)17(26-3)12-15(16)19(23-20)25-10-8-21-9-11-25/h12-14,21H,4-11H2,1-3H3
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n/an/a 100n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50252324
PNG
(CHEMBL4100138)
Show SMILES C(COc1ccc2nc(oc2c1)-c1cccc(NC2CCN(Cc3ccccc3)CC2)c1)CN1CCCC1
Show InChI InChI=1S/C32H38N4O2/c1-2-8-25(9-3-1)24-36-19-14-27(15-20-36)33-28-11-6-10-26(22-28)32-34-30-13-12-29(23-31(30)38-32)37-21-7-18-35-16-4-5-17-35/h1-3,6,8-13,22-23,27,33H,4-5,7,14-21,24H2
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n/an/a 100n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at TLR9 in human plasmacytoid dendritic cells assessed as inhibition of CpGA-induced IFN-alpha production after 18 hrs by ELISA


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467780
PNG
(CHEBI:5801 | HYDROXYCHLOROQUINE | Hydroxychloroqui...)
Show SMILES CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
Show InChI InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)
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n/an/a 110n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467785
PNG
(CHEMBL4283550)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N(C)C)N1CCN(CC1)C(=O)C(C)C
Show InChI InChI=1S/C26H40N6O3/c1-19(2)25(33)32-14-12-31(13-15-32)24-20-17-22(34-5)23(18-21(20)27-26(28-24)29(3)4)35-16-8-11-30-9-6-7-10-30/h17-19H,6-16H2,1-5H3
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n/an/a 110n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467777
PNG
(CHEMBL4290193)
Show SMILES COc1cc2c(nc(nc2cc1OCc1ccccc1)N(C)C)N1CCNCC1
Show InChI InChI=1S/C22H27N5O2/c1-26(2)22-24-18-14-20(29-15-16-7-5-4-6-8-16)19(28-3)13-17(18)21(25-22)27-11-9-23-10-12-27/h4-8,13-14,23H,9-12,15H2,1-3H3
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n/an/a 130n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 3/8/9


(Homo sapiens (Human))
BDBM50252324
PNG
(CHEMBL4100138)
Show SMILES C(COc1ccc2nc(oc2c1)-c1cccc(NC2CCN(Cc3ccccc3)CC2)c1)CN1CCCC1
Show InChI InChI=1S/C32H38N4O2/c1-2-8-25(9-3-1)24-36-19-14-27(15-20-36)33-28-11-6-10-26(22-28)32-34-30-13-12-29(23-31(30)38-32)37-21-7-18-35-16-4-5-17-35/h1-3,6,8-13,22-23,27,33H,4-5,7,14-21,24H2
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n/an/a 130n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK293 cells assessed as inhibition of CpGB-induced NF-kappaB activation after 24 hrs by spectrophotom...


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50252292
PNG
(CHEMBL4067391)
Show SMILES C(COc1ccc2nc(oc2c1)-c1cccc(c1)C1CCNCC1)CN1CCCC1
Show InChI InChI=1S/C25H31N3O2/c1-2-14-28(13-1)15-4-16-29-22-7-8-23-24(18-22)30-25(27-23)21-6-3-5-20(17-21)19-9-11-26-12-10-19/h3,5-8,17-19,26H,1-2,4,9-16H2
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PC sid
UniChem

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n/an/a 133n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK293 cells assessed as inhibition of CpGB-induced NF-kappaB activation after 24 hrs by spectrophotom...


Eur J Med Chem 134: 334-347 (2017)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467795
PNG
(CHEMBL4290016)
Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCCC1)N1CCN(CC1)C1CCCC1
Show InChI InChI=1S/C25H37N5O2/c1-31-23-17-21-22(18-24(23)32-16-6-11-28-9-4-5-10-28)26-19-27-25(21)30-14-12-29(13-15-30)20-7-2-3-8-20/h17-20H,2-16H2,1H3
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UniChem
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n/an/a 200n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467765
PNG
(CHEMBL4287984)
Show SMILES COc1cc2c(nc(nc2cc1OCCCN1CCCC1)N(C)C)N1CCN(CC1)S(=O)(=O)C(C)C
Show InChI InChI=1S/C25H40N6O4S/c1-19(2)36(32,33)31-14-12-30(13-15-31)24-20-17-22(34-5)23(18-21(20)26-25(27-24)28(3)4)35-16-8-11-29-9-6-7-10-29/h17-19H,6-16H2,1-5H3
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UniChem
PubMed
n/an/a 240n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
Toll-like receptor 9 (TLR9)


(Homo sapiens (Human))
BDBM50467768
PNG
(CHEMBL4284406)
Show SMILES COc1cc2c(nc(nc2cc1OCc1ccccc1)N(C)C)N1CCN(C)CC1
Show InChI InChI=1S/C23H29N5O2/c1-26(2)23-24-19-15-21(30-16-17-8-6-5-7-9-17)20(29-4)14-18(19)22(25-23)28-12-10-27(3)11-13-28/h5-9,14-15H,10-13,16H2,1-4H3
UniProtKB/SwissProt

GoogleScholar
UniChem
PubMed
n/an/a 260n/an/an/an/an/an/a



CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL


Assay Description
Antagonist activity at human TLR9 expressed in HEK-Blue cells assessed as reduction in CpGB-induced NF-kappaB levels after 24 hrs by spectrophotometr...


Eur J Med Chem 159: 187-205 (2018)

More data for this
Ligand-Target Pair
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