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Compile Data Set for Download or QSAR

Found 87 hits from Cell Therapeutics, Inc.   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141250
PNG
(CHEMBL34896 | [4-Chloro-3-(5-chloro-benzothiazol-2...)
Show SMILES Clc1ccc2sc(nc2c1)-c1cc(NC(=O)OCC#C)ccc1Cl
Show InChI InChI=1S/C17H10Cl2N2O2S/c1-2-7-23-17(22)20-11-4-5-13(19)12(9-11)16-21-14-8-10(18)3-6-15(14)24-16/h1,3-6,8-9H,7H2,(H,20,22)
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n/an/a 6n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141306
PNG
(CHEMBL286394 | N-[4-Chloro-3-(5-chloro-benzothiazo...)
Show SMILES Clc1ccc2sc(nc2c1)-c1cc(NC(=O)CC#N)ccc1Cl
Show InChI InChI=1S/C16H9Cl2N3OS/c17-9-1-4-14-13(7-9)21-16(23-14)11-8-10(2-3-12(11)18)20-15(22)5-6-19/h1-4,7-8H,5H2,(H,20,22)
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n/an/a 15n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141246
PNG
(CHEMBL35388 | [4-Chloro-3-(5-trifluoromethyl-benzo...)
Show SMILES FC(F)(F)c1ccc2sc(nc2c1)-c1cc(NC(=O)OCC#C)ccc1Cl
Show InChI InChI=1S/C18H10ClF3N2O2S/c1-2-7-26-17(25)23-11-4-5-13(19)12(9-11)16-24-14-8-10(18(20,21)22)3-6-15(14)27-16/h1,3-6,8-9H,7H2,(H,23,25)
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n/an/a 15n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141255
PNG
(CHEMBL35508 | [3-(5-Chloro-benzothiazol-2-yl)-4-me...)
Show SMILES Cc1ccc(NC(=O)OCC#C)cc1-c1nc2cc(Cl)ccc2s1
Show InChI InChI=1S/C18H13ClN2O2S/c1-3-8-23-18(22)20-13-6-4-11(2)14(10-13)17-21-15-9-12(19)5-7-16(15)24-17/h1,4-7,9-10H,8H2,2H3,(H,20,22)
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n/an/a 15n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50144706
PNG
(6-(5-Chloro-2-ethoxy-phenyl)-N*4*-(4-chloro-phenyl...)
Show SMILES CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(Cl)cc2)nc(N)n1
Show InChI InChI=1S/C18H16Cl2N4O/c1-2-25-16-8-5-12(20)9-14(16)15-10-17(24-18(21)23-15)22-13-6-3-11(19)4-7-13/h3-10H,2H2,1H3,(H3,21,22,23,24)
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n/an/a 17n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141254
PNG
(CHEMBL422579 | N-[4-Chloro-3-(5-chloro-benzooxazol...)
Show SMILES Clc1ccc2oc(nc2c1)-c1cc(NC(=O)CC#N)ccc1Cl
Show InChI InChI=1S/C16H9Cl2N3O2/c17-9-1-4-14-13(7-9)21-16(23-14)11-8-10(2-3-12(11)18)20-15(22)5-6-19/h1-4,7-8H,5H2,(H,20,22)
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n/an/a 27n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141279
PNG
(CHEMBL32894 | [4-Chloro-3-(5-chloro-benzooxazol-2-...)
Show SMILES Clc1ccc2oc(nc2c1)-c1cc(NC(=O)OCC#C)ccc1Cl
Show InChI InChI=1S/C17H10Cl2N2O3/c1-2-7-23-17(22)20-11-4-5-13(19)12(9-11)16-21-14-8-10(18)3-6-15(14)24-16/h1,3-6,8-9H,7H2,(H,20,22)
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n/an/a 35n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50172956
PNG
(4-(5-Chloro-2-methoxy-phenyl)-N-(4-chloro-phenyl)-...)
Show SMILES COc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C18H15Cl2N3O/c1-24-16-7-4-13(20)10-15(16)11-8-17(21)23-18(9-11)22-14-5-2-12(19)3-6-14/h2-10H,1H3,(H3,21,22,23)
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n/an/a 40n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141269
PNG
(CHEMBL284111 | [4-Chloro-3-(5-chloro-benzothiazol-...)
Show SMILES COC(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(Cl)ccc2s1
Show InChI InChI=1S/C15H10Cl2N2O2S/c1-21-15(20)18-9-3-4-11(17)10(7-9)14-19-12-6-8(16)2-5-13(12)22-14/h2-7H,1H3,(H,18,20)
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n/an/a 40n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50172951
PNG
(6-(5-Chloro-2-methoxy-phenyl)-N-(4-chloro-phenyl)-...)
Show SMILES COc1ccc(Cl)cc1-c1nc(N)nc(Nc2ccc(Cl)cc2)n1
Show InChI InChI=1S/C16H13Cl2N5O/c1-24-13-7-4-10(18)8-12(13)14-21-15(19)23-16(22-14)20-11-5-2-9(17)3-6-11/h2-8H,1H3,(H3,19,20,21,22,23)
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n/an/a 45n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141251
PNG
((3-Benzooxazol-2-yl-4-chloro-phenyl)-carbamic acid...)
Show SMILES Clc1ccc(NC(=O)OCC#C)cc1-c1nc2ccccc2o1
Show InChI InChI=1S/C17H11ClN2O3/c1-2-9-22-17(21)19-11-7-8-13(18)12(10-11)16-20-14-5-3-4-6-15(14)23-16/h1,3-8,10H,9H2,(H,19,21)
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n/an/a 50n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50172950
PNG
(4-[6-Amino-4-(5-chloro-2-ethoxy-phenyl)-pyridin-2-...)
Show SMILES CCOc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(C=O)cc2)c1
Show InChI InChI=1S/C20H18ClN3O2/c1-2-26-18-8-5-15(21)11-17(18)14-9-19(22)24-20(10-14)23-16-6-3-13(12-25)4-7-16/h3-12H,2H2,1H3,(H3,22,23,24)
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Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141297
PNG
(CHEMBL35564 | N-[4-Chloro-3-(5-trifluoromethyl-ben...)
Show SMILES FC(F)(F)c1ccc2sc(nc2c1)-c1cc(NC(=O)CC#N)ccc1Cl
Show InChI InChI=1S/C17H9ClF3N3OS/c18-12-3-2-10(23-15(25)5-6-22)8-11(12)16-24-13-7-9(17(19,20)21)1-4-14(13)26-16/h1-4,7-8H,5H2,(H,23,25)
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n/an/a 50n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50172955
PNG
(4-(5-Chloro-2-ethoxy-phenyl)-N-(4-chloro-phenyl)-p...)
Show SMILES CCOc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C19H17Cl2N3O/c1-2-25-17-8-5-14(21)11-16(17)12-9-18(22)24-19(10-12)23-15-6-3-13(20)4-7-15/h3-11H,2H2,1H3,(H3,22,23,24)
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n/an/a 50n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50144724
PNG
(6-(5-Chloro-2-methoxy-phenyl)-N*4*-(4-chloro-pheny...)
Show SMILES COc1ccc(Cl)cc1-c1cc(Nc2ccc(Cl)cc2)nc(N)n1
Show InChI InChI=1S/C17H14Cl2N4O/c1-24-15-7-4-11(19)8-13(15)14-9-16(23-17(20)22-14)21-12-5-2-10(18)3-6-12/h2-9H,1H3,(H3,20,21,22,23)
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n/an/a 54n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141287
PNG
(5TT4A4MBLR | CHEMBL36501 | CT 32228 | CT-32228 | H...)
Show SMILES Cc1ccc(Cl)cc1-c1nc(N)nc(Nc2ccc(Br)cc2)n1
Show InChI InChI=1S/C16H13BrClN5/c1-9-2-5-11(18)8-13(9)14-21-15(19)23-16(22-14)20-12-6-3-10(17)4-7-12/h2-8H,1H3,(H3,19,20,21,22,23)
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n/an/a 60n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141258
PNG
(CHEMBL418604 | [4-Chloro-3-(5-chloro-1-methyl-1H-b...)
Show SMILES Cn1c(nc2cc(Cl)ccc12)-c1cc(NC(=O)OCC#C)ccc1Cl
Show InChI InChI=1S/C18H13Cl2N3O2/c1-3-8-25-18(24)21-12-5-6-14(20)13(10-12)17-22-15-9-11(19)4-7-16(15)23(17)2/h1,4-7,9-10H,8H2,2H3,(H,21,24)
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Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141296
PNG
(CHEMBL32731 | N-(3-Benzothiazol-2-yl-4-methyl-phen...)
Show SMILES Cc1ccc(NC(=O)CC#N)cc1-c1nc2ccccc2s1
Show InChI InChI=1S/C17H13N3OS/c1-11-6-7-12(19-16(21)8-9-18)10-13(11)17-20-14-4-2-3-5-15(14)22-17/h2-7,10H,8H2,1H3,(H,19,21)
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n/an/a 70n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50172951
PNG
(6-(5-Chloro-2-methoxy-phenyl)-N-(4-chloro-phenyl)-...)
Show SMILES COc1ccc(Cl)cc1-c1nc(N)nc(Nc2ccc(Cl)cc2)n1
Show InChI InChI=1S/C16H13Cl2N5O/c1-24-13-7-4-10(18)8-12(13)14-21-15(19)23-16(22-14)20-11-5-2-9(17)3-6-11/h2-8H,1H3,(H3,19,20,21,22,23)
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n/an/a 70n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141283
PNG
(CHEMBL286639 | [4-Chloro-3-(5-chloro-benzooxazol-2...)
Show SMILES CC#CCOC(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(Cl)ccc2o1
Show InChI InChI=1S/C18H12Cl2N2O3/c1-2-3-8-24-18(23)21-12-5-6-14(20)13(10-12)17-22-15-9-11(19)4-7-16(15)25-17/h4-7,9-10H,8H2,1H3,(H,21,23)
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n/an/a 75n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141291
PNG
(CHEMBL32553 | [4-Chloro-3-(5-chloro-benzooxazol-2-...)
Show SMILES Clc1ccc2oc(nc2c1)-c1cc(NC(=O)OCCC#C)ccc1Cl
Show InChI InChI=1S/C18H12Cl2N2O3/c1-2-3-8-24-18(23)21-12-5-6-14(20)13(10-12)17-22-15-9-11(19)4-7-16(15)25-17/h1,4-7,9-10H,3,8H2,(H,21,23)
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n/an/a 75n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50172952
PNG
(CHEMBL193588 | {4-[6-Amino-4-(5-chloro-2-ethoxy-ph...)
Show SMILES CCOc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(CO)cc2)c1
Show InChI InChI=1S/C20H20ClN3O2/c1-2-26-18-8-5-15(21)11-17(18)14-9-19(22)24-20(10-14)23-16-6-3-13(12-25)4-7-16/h3-11,25H,2,12H2,1H3,(H3,22,23,24)
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n/an/a 99n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141308
PNG
(CHEMBL418404 | Pent-4-ynoic acid [4-chloro-3-(5-ch...)
Show SMILES Clc1ccc2oc(nc2c1)-c1cc(NC(=O)CCC#C)ccc1Cl
Show InChI InChI=1S/C18H12Cl2N2O2/c1-2-3-4-17(23)21-12-6-7-14(20)13(10-12)18-22-15-9-11(19)5-8-16(15)24-18/h1,5-10H,3-4H2,(H,21,23)
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n/an/a 100n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141281
PNG
(CHEMBL35006 | N-[4-Chloro-3-(5-methyl-benzooxazol-...)
Show SMILES Cc1ccc2oc(nc2c1)-c1cc(NC(=O)CC#N)ccc1Cl
Show InChI InChI=1S/C17H12ClN3O2/c1-10-2-5-15-14(8-10)21-17(23-15)12-9-11(3-4-13(12)18)20-16(22)6-7-19/h2-5,8-9H,6H2,1H3,(H,20,22)
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n/an/a 100n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141272
PNG
(1-[4-Chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl]-...)
Show SMILES Clc1ccc2oc(nc2c1)-c1cc(NC(=O)NCC#C)ccc1Cl
Show InChI InChI=1S/C17H11Cl2N3O2/c1-2-7-20-17(23)21-11-4-5-13(19)12(9-11)16-22-14-8-10(18)3-6-15(14)24-16/h1,3-6,8-9H,7H2,(H2,20,21,23)
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n/an/a 100n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141280
PNG
(CHEMBL33773 | [3-(5-Chloro-benzooxazol-2-yl)-4-met...)
Show SMILES Cc1ccc(NC(=O)OCC#C)cc1-c1nc2cc(Cl)ccc2o1
Show InChI InChI=1S/C18H13ClN2O3/c1-3-8-23-18(22)20-13-6-4-11(2)14(10-13)17-21-15-9-12(19)5-7-16(15)24-17/h1,4-7,9-10H,8H2,2H3,(H,20,22)
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n/an/a 100n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141290
PNG
(CHEMBL34938 | [4-Chloro-3-(1-methyl-5-trifluoromet...)
Show SMILES Cn1c(nc2cc(ccc12)C(F)(F)F)-c1cc(NC(=O)OCC#C)ccc1Cl
Show InChI InChI=1S/C19H13ClF3N3O2/c1-3-8-28-18(27)24-12-5-6-14(20)13(10-12)17-25-15-9-11(19(21,22)23)4-7-16(15)26(17)2/h1,4-7,9-10H,8H2,2H3,(H,24,27)
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n/an/a 120n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50172949
PNG
(6-(5-Chloro-2-ethoxy-phenyl)-N-(4-chloro-phenyl)-[...)
Show SMILES CCOc1ccc(Cl)cc1-c1nc(N)nc(Nc2ccc(Cl)cc2)n1
Show InChI InChI=1S/C17H15Cl2N5O/c1-2-25-14-8-5-11(19)9-13(14)15-22-16(20)24-17(23-15)21-12-6-3-10(18)4-7-12/h3-9H,2H2,1H3,(H3,20,21,22,23,24)
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n/an/a 140n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141284
PNG
(CHEMBL35051 | [4-Chloro-3-(5-trifluoromethyl-benzo...)
Show SMILES FC(F)(F)c1ccc2oc(nc2c1)-c1cc(NC(=O)OCC#C)ccc1Cl
Show InChI InChI=1S/C18H10ClF3N2O3/c1-2-7-26-17(25)23-11-4-5-13(19)12(9-11)16-24-14-8-10(18(20,21)22)3-6-15(14)27-16/h1,3-6,8-9H,7H2,(H,23,25)
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n/an/a 140n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141257
PNG
(CHEMBL286925 | [4-Chloro-3-(4-methyl-benzooxazol-2...)
Show SMILES Cc1cccc2oc(nc12)-c1cc(NC(=O)OCC#C)ccc1Cl
Show InChI InChI=1S/C18H13ClN2O3/c1-3-9-23-18(22)20-12-7-8-14(19)13(10-12)17-21-16-11(2)5-4-6-15(16)24-17/h1,4-8,10H,9H2,2H3,(H,20,22)
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n/an/a 160n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141282
PNG
(2-Azido-N-[4-chloro-3-(5-chloro-benzooxazol-2-yl)-...)
Show SMILES Clc1ccc2oc(nc2c1)-c1cc(NC(=O)CN=[N+]=[N-])ccc1Cl
Show InChI InChI=1S/C15H9Cl2N5O2/c16-8-1-4-13-12(5-8)21-15(24-13)10-6-9(2-3-11(10)17)20-14(23)7-19-22-18/h1-6H,7H2,(H,20,23)
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n/an/a 170n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141271
PNG
(CHEMBL34585 | [4-Chloro-3-(5-methyl-benzooxazol-2-...)
Show SMILES Cc1ccc2oc(nc2c1)-c1cc(NC(=O)OCC#C)ccc1Cl
Show InChI InChI=1S/C18H13ClN2O3/c1-3-8-23-18(22)20-12-5-6-14(19)13(10-12)17-21-15-9-11(2)4-7-16(15)24-17/h1,4-7,9-10H,8H2,2H3,(H,20,22)
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n/an/a 190n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141273
PNG
(CHEMBL33960 | [4-Chloro-3-(5-trifluoromethyl-benzo...)
Show SMILES COC(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(ccc2s1)C(F)(F)F
Show InChI InChI=1S/C16H10ClF3N2O2S/c1-24-15(23)21-9-3-4-11(17)10(7-9)14-22-12-6-8(16(18,19)20)2-5-13(12)25-14/h2-7H,1H3,(H,21,23)
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n/an/a 200n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50172959
PNG
(4-(5-Chloro-2-methoxy-phenyl)-N-p-tolyl-pyridine-2...)
Show SMILES COc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(C)cc2)c1
Show InChI InChI=1S/C19H18ClN3O/c1-12-3-6-15(7-4-12)22-19-10-13(9-18(21)23-19)16-11-14(20)5-8-17(16)24-2/h3-11H,1-2H3,(H3,21,22,23)
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n/an/a 240n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50172949
PNG
(6-(5-Chloro-2-ethoxy-phenyl)-N-(4-chloro-phenyl)-[...)
Show SMILES CCOc1ccc(Cl)cc1-c1nc(N)nc(Nc2ccc(Cl)cc2)n1
Show InChI InChI=1S/C17H15Cl2N5O/c1-2-25-14-8-5-11(19)9-13(14)15-22-16(20)24-17(23-15)21-12-6-3-10(18)4-7-12/h3-9H,2H2,1H3,(H3,20,21,22,23,24)
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n/an/a 260n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50172948
PNG
(4-[6-Amino-4-(5-chloro-2-methoxy-phenyl)-pyridin-2...)
Show SMILES COc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(C=O)cc2)c1
Show InChI InChI=1S/C19H16ClN3O2/c1-25-17-7-4-14(20)10-16(17)13-8-18(21)23-19(9-13)22-15-5-2-12(11-24)3-6-15/h2-11H,1H3,(H3,21,22,23)
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n/an/a 260n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141275
PNG
(CHEMBL35582 | [4-Chloro-3-(5-chloro-benzooxazol-2-...)
Show SMILES COC(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(Cl)ccc2o1
Show InChI InChI=1S/C15H10Cl2N2O3/c1-21-15(20)18-9-3-4-11(17)10(7-9)14-19-12-6-8(16)2-5-13(12)22-14/h2-7H,1H3,(H,18,20)
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n/an/a 300n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141301
PNG
(CHEMBL32938 | N-[4-Chloro-3-(5-chloro-1-methyl-1H-...)
Show SMILES Cn1c(nc2cc(Cl)ccc12)-c1cc(NC(=O)CC#N)ccc1Cl
Show InChI InChI=1S/C17H12Cl2N4O/c1-23-15-5-2-10(18)8-14(15)22-17(23)12-9-11(3-4-13(12)19)21-16(24)6-7-20/h2-5,8-9H,6H2,1H3,(H,21,24)
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n/an/a 300n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141245
PNG
(CHEMBL34636 | [4-Chloro-3-(6-methyl-benzooxazol-2-...)
Show SMILES COC(=O)Nc1ccc(Cl)c(c1)-c1nc2ccc(C)cc2o1
Show InChI InChI=1S/C16H13ClN2O3/c1-9-3-6-13-14(7-9)22-15(19-13)11-8-10(4-5-12(11)17)18-16(20)21-2/h3-8H,1-2H3,(H,18,20)
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n/an/a 400n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50172954
PNG
(4-(5-Chloro-2-ethoxy-phenyl)-N-p-tolyl-pyridine-2,...)
Show SMILES CCOc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(C)cc2)c1
Show InChI InChI=1S/C20H20ClN3O/c1-3-25-18-9-6-15(21)12-17(18)14-10-19(22)24-20(11-14)23-16-7-4-13(2)5-8-16/h4-12H,3H2,1-2H3,(H3,22,23,24)
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n/an/a 490n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against Lysophosphatidic acid acyltransferase-beta enzyme overexpressed in Sf9 insect cell membrane


Bioorg Med Chem Lett 15: 4703-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.055
BindingDB Entry DOI: 10.7270/Q29G5MB2
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141288
PNG
(CHEMBL33877 | Pent-4-ynoic acid [4-chloro-3-(5-met...)
Show SMILES Cc1ccc2oc(nc2c1)-c1cc(NC(=O)CCC#C)ccc1Cl
Show InChI InChI=1S/C19H15ClN2O2/c1-3-4-5-18(23)21-13-7-8-15(20)14(11-13)19-22-16-10-12(2)6-9-17(16)24-19/h1,6-11H,4-5H2,2H3,(H,21,23)
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n/an/a 500n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141289
PNG
(CHEMBL33823 | [4-Chloro-3-(4-methyl-benzooxazol-2-...)
Show SMILES COC(=O)Nc1ccc(Cl)c(c1)-c1nc2c(C)cccc2o1
Show InChI InChI=1S/C16H13ClN2O3/c1-9-4-3-5-13-14(9)19-15(22-13)11-8-10(6-7-12(11)17)18-16(20)21-2/h3-8H,1-2H3,(H,18,20)
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n/an/a 500n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141248
PNG
((3-Benzooxazol-2-yl-4-chloro-phenyl)-carbamic acid...)
Show SMILES COC(=O)Nc1ccc(Cl)c(c1)-c1nc2ccccc2o1
Show InChI InChI=1S/C15H11ClN2O3/c1-20-15(19)17-9-6-7-11(16)10(8-9)14-18-12-4-2-3-5-13(12)21-14/h2-8H,1H3,(H,17,19)
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n/an/a 500n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141295
PNG
(CHEMBL286185 | [3-(5-Chloro-benzooxazol-2-yl)-4-me...)
Show SMILES COC(=O)Nc1ccc(C)c(c1)-c1nc2cc(Cl)ccc2o1
Show InChI InChI=1S/C16H13ClN2O3/c1-9-3-5-11(18-16(20)21-2)8-12(9)15-19-13-7-10(17)4-6-14(13)22-15/h3-8H,1-2H3,(H,18,20)
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n/an/a 550n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141292
PNG
(2-Azido-N-[4-chloro-3-(5-methyl-benzooxazol-2-yl)-...)
Show SMILES Cc1ccc2oc(nc2c1)-c1cc(NC(=O)CN=[N+]=[N-])ccc1Cl
Show InChI InChI=1S/C16H12ClN5O2/c1-9-2-5-14-13(6-9)21-16(24-14)11-7-10(3-4-12(11)17)20-15(23)8-19-22-18/h2-7H,8H2,1H3,(H,20,23)
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n/an/a 600n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141294
PNG
(CHEMBL290583 | [4-Chloro-3-(5-chloro-1-methyl-1H-b...)
Show SMILES COC(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(Cl)ccc2n1C
Show InChI InChI=1S/C16H13Cl2N3O2/c1-21-14-6-3-9(17)7-13(14)20-15(21)11-8-10(4-5-12(11)18)19-16(22)23-2/h3-8H,1-2H3,(H,19,22)
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n/an/a 650n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141268
PNG
(CHEMBL34886 | [4-Chloro-3-(5-trifluoromethyl-benzo...)
Show SMILES COC(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(ccc2o1)C(F)(F)F
Show InChI InChI=1S/C16H10ClF3N2O3/c1-24-15(23)21-9-3-4-11(17)10(7-9)14-22-12-6-8(16(18,19)20)2-5-13(12)25-14/h2-7H,1H3,(H,21,23)
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n/an/a 800n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141300
PNG
(1-[4-Chloro-3-(5-chloro-benzooxazol-2-yl)-phenyl]-...)
Show SMILES CNC(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(Cl)ccc2o1
Show InChI InChI=1S/C15H11Cl2N3O2/c1-18-15(21)19-9-3-4-11(17)10(7-9)14-20-12-6-8(16)2-5-13(12)22-14/h2-7H,1H3,(H2,18,19,21)
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n/an/a 950n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141307
PNG
(CHEMBL35001 | [4-Chloro-3-(5-methyl-benzooxazol-2-...)
Show SMILES COC(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(C)ccc2o1
Show InChI InChI=1S/C16H13ClN2O3/c1-9-3-6-14-13(7-9)19-15(22-14)11-8-10(4-5-12(11)17)18-16(20)21-2/h3-8H,1-2H3,(H,18,20)
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n/an/a 1.00E+3n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
1-acylglycerol-3-phosphate O-acyltransferase beta


(Homo sapiens)
BDBM50141265
PNG
(CHEMBL35806 | [4-Chloro-3-(5-methyl-benzooxazol-2-...)
Show SMILES Cc1ccc2oc(nc2c1)-c1cc(NC(=O)OCC=C)ccc1Cl
Show InChI InChI=1S/C18H15ClN2O3/c1-3-8-23-18(22)20-12-5-6-14(19)13(10-12)17-21-15-9-11(2)4-7-16(15)24-17/h3-7,9-10H,1,8H2,2H3,(H,20,22)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Cell Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes


Bioorg Med Chem Lett 14: 1455-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.023
BindingDB Entry DOI: 10.7270/Q20Z72Q5
More data for this
Ligand-Target Pair
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