BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 192 hits from Chosun University   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sialidase


(Clostridium perfringens)
BDBM50311581
PNG
(CHEMBL1086764 | erysubin E)
Show SMILES CC(C)=CCc1cc2[C@@H]3Oc4c(ccc5OC(C)(C)C=Cc45)[C@]3(O)COc2cc1O
Show InChI InChI=1S/C25H26O5/c1-14(2)5-6-15-11-17-21(12-19(15)26)28-13-25(27)18-7-8-20-16(22(18)29-23(17)25)9-10-24(3,4)30-20/h5,7-12,23,26-27H,6,13H2,1-4H3/t23-,25+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
240n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
Sialidase


(Clostridium perfringens)
BDBM50317430
PNG
(CHEMBL454849 | Erythrabyssin I | cristacarpin | cr...)
Show SMILES COc1ccc2c(O[C@H]3c4ccc(O)cc4OC[C@@]23O)c1CC=C(C)C
Show InChI InChI=1S/C21H22O5/c1-12(2)4-6-14-17(24-3)9-8-16-19(14)26-20-15-7-5-13(22)10-18(15)25-11-21(16,20)23/h4-5,7-10,20,22-23H,6,11H2,1-3H3/t20-,21+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
310n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
Sialidase


(Clostridium perfringens)
BDBM50317435
PNG
(CHEMBL1096406 | Erythribyssin O)
Show SMILES CC(C)=CCc1c(O)ccc2c3COc4cc(O)c(C=O)cc4-c3oc12
Show InChI InChI=1S/C21H18O5/c1-11(2)3-4-14-17(23)6-5-13-16-10-25-19-8-18(24)12(9-22)7-15(19)21(16)26-20(13)14/h3,5-9,23-24H,4,10H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.21E+3n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
Sialidase


(Clostridium perfringens)
BDBM50311583
PNG
(Abyssinone II | CHEMBL508534 | phaseolidin | phase...)
Show SMILES CC(C)=CCc1c2O[C@@H]3[C@@H](COc4cc(O)ccc34)c2ccc1O
Show InChI InChI=1S/C20H20O4/c1-11(2)3-5-14-17(22)8-7-13-16-10-23-18-9-12(21)4-6-15(18)20(16)24-19(13)14/h3-4,6-9,16,20-22H,5,10H2,1-2H3/t16-,20-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.78E+3n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
Sialidase


(Clostridium perfringens)
BDBM50311586
PNG
(CHEMBL1088462 | erystagallin A)
Show SMILES COc1ccc2c(O[C@H]3c4cc(CC=C(C)C)c(O)cc4OC[C@@]23O)c1CC=C(C)C
Show InChI InChI=1S/C26H30O5/c1-15(2)6-8-17-12-19-23(13-21(17)27)30-14-26(28)20-10-11-22(29-5)18(9-7-16(3)4)24(20)31-25(19)26/h6-7,10-13,25,27-28H,8-9,14H2,1-5H3/t25-,26+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.80E+3n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
Sialidase


(Clostridium perfringens)
BDBM50317436
PNG
(CHEMBL1096407 | calopocarpin)
Show SMILES CC(C)=CCc1cc2[C@@H]3Oc4cc(O)ccc4[C@@H]3COc2cc1O
Show InChI InChI=1S/C20H20O4/c1-11(2)3-4-12-7-15-18(9-17(12)22)23-10-16-14-6-5-13(21)8-19(14)24-20(15)16/h3,5-9,16,20-22H,4,10H2,1-2H3/t16-,20-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.09E+3n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
Sialidase


(Clostridium perfringens)
BDBM50317434
PNG
(CHEMBL1097045 | eryvarin D)
Show SMILES COc1ccc2c3COc4cc(O)ccc4-c3oc2c1CC=C(C)C
Show InChI InChI=1S/C21H20O4/c1-12(2)4-6-15-18(23-3)9-8-14-17-11-24-19-10-13(22)5-7-16(19)21(17)25-20(14)15/h4-5,7-10,22H,6,11H2,1-3H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.55E+3n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
Sialidase


(Clostridium perfringens)
BDBM50317431
PNG
(CHEMBL1098413 | demethylmedicarpin)
Show SMILES Oc1ccc2[C@@H]3COc4cc(O)ccc4[C@@H]3Oc2c1
Show InChI InChI=1S/C15H12O4/c16-8-2-4-11-13(5-8)18-7-12-10-3-1-9(17)6-14(10)19-15(11)12/h1-6,12,15-17H,7H2/t12-,15-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.83E+3n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
Sialidase


(Clostridium perfringens)
BDBM50317437
PNG
(CHEMBL1096408 | Erythribyssin L)
Show SMILES CC(C)=CCc1c2O[C@@H]3[C@@H](COc4cc5OC(C)(C)C(O)Cc5cc34)c2ccc1O
Show InChI InChI=1S/C25H28O5/c1-13(2)5-6-16-19(26)8-7-15-18-12-28-21-11-20-14(10-22(27)25(3,4)30-20)9-17(21)24(18)29-23(15)16/h5,7-9,11,18,22,24,26-27H,6,10,12H2,1-4H3/t18-,22?,24-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.13E+3n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
Sialidase


(Clostridium perfringens)
BDBM50317438
PNG
(Abyssinone I | CHEMBL448350 | phaseollin)
Show SMILES CC1(C)Oc2ccc3[C@@H]4COc5cc(O)ccc5[C@@H]4Oc3c2C=C1
Show InChI InChI=1S/C20H18O4/c1-20(2)8-7-14-16(24-20)6-5-12-15-10-22-17-9-11(21)3-4-13(17)19(15)23-18(12)14/h3-9,15,19,21H,10H2,1-2H3/t15-,19-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4.84E+3n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Competitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
Sialidase


(Clostridium perfringens)
BDBM50317433
PNG
(CHEMBL1098729 | isoneorautenol)
Show SMILES CC1(C)Oc2cc3O[C@@H]4[C@@H](COc5cc(O)ccc45)c3cc2C=C1
Show InChI InChI=1S/C20H18O4/c1-20(2)6-5-11-7-14-15-10-22-17-8-12(21)3-4-13(17)19(15)23-18(14)9-16(11)24-20/h3-9,15,19,21H,10H2,1-2H3/t15-,19-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.10E+4n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
Sialidase


(Clostridium perfringens)
BDBM50317439
PNG
(CHEMBL1095422 | erysubin D)
Show SMILES CC(C)=CCc1cc2[C@@H]3Oc4c(ccc5OC(C)(C)C(O)Cc45)[C@@H]3COc2cc1O
Show InChI InChI=1S/C25H28O5/c1-13(2)5-6-14-9-16-21(11-19(14)26)28-12-18-15-7-8-20-17(23(15)29-24(16)18)10-22(27)25(3,4)30-20/h5,7-9,11,18,22,24,26-27H,6,10,12H2,1-4H3/t18-,22?,24-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.52E+4n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Competitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
Sialidase


(Clostridium perfringens)
BDBM50317432
PNG
(CHEMBL1098728 | NEORAUTENOL)
Show SMILES CC1(C)Oc2cc3OC[C@@H]4[C@@H](Oc5cc(O)ccc45)c3cc2C=C1
Show InChI InChI=1S/C20H18O4/c1-20(2)6-5-11-7-14-17(9-16(11)24-20)22-10-15-13-4-3-12(21)8-18(13)23-19(14)15/h3-9,15,19,21H,10H2,1-2H3/t15-,19-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.17E+4n/an/an/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Noncompetitive inhibition of Clostridium perfringens neuraminidase


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50066953
PNG
(CHEMBL3403240)
Show SMILES Brc1cc(\C=C2/SC(=O)NC2=O)ccc1OCCc1ccccc1
Show InChI InChI=1S/C18H14BrNO3S/c19-14-10-13(11-16-17(21)20-18(22)24-16)6-7-15(14)23-9-8-12-4-2-1-3-5-12/h1-7,10-11H,8-9H2,(H,20,21,22)/b16-11-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of 15-PGDH (unknown origin) by fluorescence spectrophotometry


Bioorg Med Chem 23: 2098-103 (2015)


Article DOI: 10.1016/j.bmc.2015.03.010
BindingDB Entry DOI: 10.7270/Q2NK3GR5
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50347952
PNG
(CHEMBL1800139 | US8637558, 11)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)c(Cl)c1
Show InChI InChI=1S/C18H20ClNO3S/c19-14-10-13(11-16-17(21)20-18(22)24-16)6-7-15(14)23-9-8-12-4-2-1-3-5-12/h6-7,10-12H,1-5,8-9H2,(H,20,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...


J Med Chem 54: 5260-4 (2011)


Article DOI: 10.1021/jm200390u
BindingDB Entry DOI: 10.7270/Q2B56K33
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50347956
PNG
(CHEMBL1800143 | US8637558, 32)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCC2CCCCC2)c(Cl)c1
Show InChI InChI=1S/C19H22ClNO3S/c20-15-11-14(12-17-18(22)21-19(23)25-17)8-9-16(15)24-10-4-7-13-5-2-1-3-6-13/h8-9,11-13H,1-7,10H2,(H,21,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...


J Med Chem 54: 5260-4 (2011)


Article DOI: 10.1021/jm200390u
BindingDB Entry DOI: 10.7270/Q2B56K33
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50347953
PNG
(CHEMBL1800140 | US8637558, 15)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)c(Br)c1
Show InChI InChI=1S/C18H20BrNO3S/c19-14-10-13(11-16-17(21)20-18(22)24-16)6-7-15(14)23-9-8-12-4-2-1-3-5-12/h6-7,10-12H,1-5,8-9H2,(H,20,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 19n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...


J Med Chem 54: 5260-4 (2011)


Article DOI: 10.1021/jm200390u
BindingDB Entry DOI: 10.7270/Q2B56K33
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50347957
PNG
(CHEMBL1800144 | US8637558, 33)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCCC2CCCCC2)c(Cl)c1
Show InChI InChI=1S/C20H24ClNO3S/c21-16-12-15(13-18-19(23)22-20(24)26-18)9-10-17(16)25-11-5-4-8-14-6-2-1-3-7-14/h9-10,12-14H,1-8,11H2,(H,22,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...


J Med Chem 54: 5260-4 (2011)


Article DOI: 10.1021/jm200390u
BindingDB Entry DOI: 10.7270/Q2B56K33
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50347950
PNG
(CHEMBL1800138)
Show SMILES COc1cc(C=C2SC(O)=NC2=O)ccc1OCCC1CCCCC1
Show InChI InChI=1S/C19H23NO4S/c1-23-16-11-14(12-17-18(21)20-19(22)25-17)7-8-15(16)24-10-9-13-5-3-2-4-6-13/h7-8,11-13H,2-6,9-10H2,1H3,(H,20,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...


J Med Chem 54: 5260-4 (2011)


Article DOI: 10.1021/jm200390u
BindingDB Entry DOI: 10.7270/Q2B56K33
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50347955
PNG
(CHEMBL1800142 | US8637558, 31)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2CCCCC2)c(Cl)c1
Show InChI InChI=1S/C17H18ClNO3S/c18-13-8-12(9-15-16(20)19-17(21)23-15)6-7-14(13)22-10-11-4-2-1-3-5-11/h6-9,11H,1-5,10H2,(H,19,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 28n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...


J Med Chem 54: 5260-4 (2011)


Article DOI: 10.1021/jm200390u
BindingDB Entry DOI: 10.7270/Q2B56K33
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378619
PNG
(CHEMBL590265 | US8637558, 3)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2cccs2)cc1
Show InChI InChI=1S/C16H13NO3S2/c18-15-14(22-16(19)17-15)10-11-3-5-12(6-4-11)20-8-7-13-2-1-9-21-13/h1-6,9-10H,7-8H2,(H,17,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 31n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378637
PNG
(CHEMBL84603 | US8637558, 35)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2CCCC2)cc1
Show InChI InChI=1S/C16H17NO3S/c18-15-14(21-16(19)17-15)9-11-5-7-13(8-6-11)20-10-12-3-1-2-4-12/h5-9,12H,1-4,10H2,(H,17,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 45n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50347954
PNG
(CHEMBL1800141 | US8637558, 30)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OC2CCCCC2)c(Cl)c1
Show InChI InChI=1S/C16H16ClNO3S/c17-12-8-10(9-14-15(19)18-16(20)22-14)6-7-13(12)21-11-4-2-1-3-5-11/h6-9,11H,1-5H2,(H,18,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 47n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...


J Med Chem 54: 5260-4 (2011)


Article DOI: 10.1021/jm200390u
BindingDB Entry DOI: 10.7270/Q2B56K33
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50347949
PNG
(CHEMBL599406 | US8637558, 46)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)cc1
Show InChI InChI=1S/C18H21NO3S/c20-17-16(23-18(21)19-17)12-14-6-8-15(9-7-14)22-11-10-13-4-2-1-3-5-13/h6-9,12-13H,1-5,10-11H2,(H,19,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 51n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50347949
PNG
(CHEMBL599406 | US8637558, 46)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)cc1
Show InChI InChI=1S/C18H21NO3S/c20-17-16(23-18(21)19-17)12-14-6-8-15(9-7-14)22-11-10-13-4-2-1-3-5-13/h6-9,12-13H,1-5,10-11H2,(H,19,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 51n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...


J Med Chem 54: 5260-4 (2011)


Article DOI: 10.1021/jm200390u
BindingDB Entry DOI: 10.7270/Q2B56K33
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378639
PNG
(CHEMBL599018 | US8637558, 37)
Show SMILES CC1CCC(COc2ccc(C=C3SC(O)=NC3=O)cc2)CC1
Show InChI InChI=1S/C18H21NO3S/c1-12-2-4-14(5-3-12)11-22-15-8-6-13(7-9-15)10-16-17(20)19-18(21)23-16/h6-10,12,14H,2-5,11H2,1H3,(H,19,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 52n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378621
PNG
(CHEMBL610221 | US8637558, 4)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2ccsc2)cc1
Show InChI InChI=1S/C16H13NO3S2/c18-15-14(22-16(19)17-15)9-11-1-3-13(4-2-11)20-7-5-12-6-8-21-10-12/h1-4,6,8-10H,5,7H2,(H,17,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378631
PNG
(CHEMBL598397 | US8637558, 24)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCC2)cc1
Show InChI InChI=1S/C17H19NO3S/c19-16-15(22-17(20)18-16)11-13-5-7-14(8-6-13)21-10-9-12-3-1-2-4-12/h5-8,11-12H,1-4,9-10H2,(H,18,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 116n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378638
PNG
(CHEMBL591466 | US8637558, 36)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccc(CCl)cc2)cc1
Show InChI InChI=1S/C18H14ClNO3S/c19-10-13-1-3-14(4-2-13)11-23-15-7-5-12(6-8-15)9-16-17(21)20-18(22)24-16/h1-9H,10-11H2,(H,20,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 124n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM118038
PNG
(CHEMBL598880 | US8637558, 62)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2COc3ccccc3O2)cc1
Show InChI InChI=1S/C19H15NO5S/c21-18-17(26-19(22)20-18)9-12-5-7-13(8-6-12)23-10-14-11-24-15-3-1-2-4-16(15)25-14/h1-9,14H,10-11H2,(H,20,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 172n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378640
PNG
(CHEMBL599019 | US8637558, 61)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCOC2CCCCC2)cc1
Show InChI InChI=1S/C18H21NO4S/c20-17-16(24-18(21)19-17)12-13-6-8-15(9-7-13)23-11-10-22-14-4-2-1-3-5-14/h6-9,12,14H,1-5,10-11H2,(H,19,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 219n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378635
PNG
(CHEMBL597576 | US8637558, 27 | US8637558, 28)
Show SMILES Cc1ccc(COc2ccc(C=C3SC(O)=NC3=O)cc2)cc1
Show InChI InChI=1S/C18H15NO3S/c1-12-2-4-14(5-3-12)11-22-15-8-6-13(7-9-15)10-16-17(20)19-18(21)23-16/h2-10H,11H2,1H3,(H,19,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 232n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378636
PNG
(CHEMBL607870 | US8637558, 29)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccc3OCOc3c2)cc1
Show InChI InChI=1S/C18H13NO5S/c20-17-16(25-18(21)19-17)8-11-1-4-13(5-2-11)22-9-12-3-6-14-15(7-12)24-10-23-14/h1-8H,9-10H2,(H,19,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 252n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378618
PNG
(CHEMBL599407 | US8637558, 5)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCN2CCS(=O)(=O)CC2)cc1
Show InChI InChI=1S/C16H18N2O5S2/c19-15-14(24-16(20)17-15)11-12-1-3-13(4-2-12)23-8-5-18-6-9-25(21,22)10-7-18/h1-4,11H,5-10H2,(H,17,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 274n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378629
PNG
(CHEMBL598182 | US8637558, 22)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2cccs2)cc1
Show InChI InChI=1S/C15H11NO3S2/c17-14-13(21-15(18)16-14)8-10-3-5-11(6-4-10)19-9-12-2-1-7-20-12/h1-8H,9H2,(H,16,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 287n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
Sialidase


(Vibrio cholerae)
BDBM50317435
PNG
(CHEMBL1096406 | Erythribyssin O)
Show SMILES CC(C)=CCc1c(O)ccc2c3COc4cc(O)c(C=O)cc4-c3oc12
Show InChI InChI=1S/C21H18O5/c1-11(2)3-4-14-17(23)6-5-13-16-10-25-19-8-18(24)12(9-22)7-15(19)21(16)26-20(13)14/h3,5-9,23-24H,4,10H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 350n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of Vibrio cholerae neuraminidase assessed as inhibition of 4-MU-NANA hydrolysis after 30 mins by spectrofluorometry


Bioorg Med Chem 18: 3335-44 (2010)


Article DOI: 10.1016/j.bmc.2010.03.005
BindingDB Entry DOI: 10.7270/Q2MW2HBM
More data for this
Ligand-Target Pair
P-glycoprotein 1


(Homo sapiens (Human))
BDBM50338982
PNG
((R)-5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3...)
Show SMILES COc1ccc(CCN(C)CCC[C@@](C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC
Show InChI InChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3/t27-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 400n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cells


Biochem Biophys Res Commun 320: 672-9 (2004)


Article DOI: 10.1016/j.bbrc.2004.06.020
BindingDB Entry DOI: 10.7270/Q2891748
More data for this
Ligand-Target Pair
P-glycoprotein 1


(Homo sapiens (Human))
BDBM50420207
PNG
(CHEMBL2074901)
Show SMILES COc1cc(OC)c2c(c1)oc(cc2=O)-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C20H20O7/c1-22-12-8-15(23-2)19-13(21)10-14(27-16(19)9-12)11-6-17(24-3)20(26-5)18(7-11)25-4/h6-10H,1-5H3
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 400n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cells


Biochem Biophys Res Commun 320: 672-9 (2004)


Article DOI: 10.1016/j.bbrc.2004.06.020
BindingDB Entry DOI: 10.7270/Q2891748
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378630
PNG
(CHEMBL598183 | US8637558, 23)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccsc2)cc1
Show InChI InChI=1S/C15H11NO3S2/c17-14-13(21-15(18)16-14)7-10-1-3-12(4-2-10)19-8-11-5-6-20-9-11/h1-7,9H,8H2,(H,16,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 429n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378646
PNG
(CHEMBL598787 | US8637558, 58)
Show SMILES OCCN1C(=O)S\C(=C/c2ccc(OCCC3CCCCC3)cc2)C1=O
Show InChI InChI=1S/C20H25NO4S/c22-12-11-21-19(23)18(26-20(21)24)14-16-6-8-17(9-7-16)25-13-10-15-4-2-1-3-5-15/h6-9,14-15,22H,1-5,10-13H2/b18-14-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 526n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378634
PNG
(CHEMBL608142)
Show SMILES COc1ccc(COc2ccc(C=C3SC(O)=NC3=O)cc2)cc1
Show InChI InChI=1S/C18H15NO4S/c1-22-14-6-4-13(5-7-14)11-23-15-8-2-12(3-9-15)10-16-17(20)19-18(21)24-16/h2-10H,11H2,1H3,(H,19,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 529n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378642
PNG
(CHEMBL599220)
Show SMILES COC(=O)C1CCC(COc2ccc(C=C3SC(O)=NC3=O)cc2)CC1
Show InChI InChI=1S/C19H21NO5S/c1-24-18(22)14-6-2-13(3-7-14)11-25-15-8-4-12(5-9-15)10-16-17(21)20-19(23)26-16/h4-5,8-10,13-14H,2-3,6-7,11H2,1H3,(H,20,21,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 620n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378627
PNG
(CHEMBL590988 | US8637558, 19)
Show SMILES Cc1ncsc1CCOc1ccc(C=C2SC(O)=NC2=O)cc1
Show InChI InChI=1S/C16H14N2O3S2/c1-10-13(22-9-17-10)6-7-21-12-4-2-11(3-5-12)8-14-15(19)18-16(20)23-14/h2-5,8-9H,6-7H2,1H3,(H,18,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 636n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378623
PNG
(CHEMBL599004 | US8637558, 6)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2ccccn2)cc1
Show InChI InChI=1S/C17H14N2O3S/c20-16-15(23-17(21)19-16)11-12-4-6-14(7-5-12)22-10-8-13-3-1-2-9-18-13/h1-7,9,11H,8,10H2,(H,19,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 660n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378620
PNG
(CHEMBL599002 | US8637558, 2)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCN2CCOCC2)cc1
Show InChI InChI=1S/C16H18N2O4S/c19-15-14(23-16(20)17-15)11-12-1-3-13(4-2-12)22-10-7-18-5-8-21-9-6-18/h1-4,11H,5-10H2,(H,17,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 713n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378625
PNG
(CHEMBL598175)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCO2)cc1
Show InChI InChI=1S/C17H19NO4S/c19-16-15(23-17(20)18-16)11-12-4-6-14(7-5-12)22-10-8-13-3-1-2-9-21-13/h4-7,11,13H,1-3,8-10H2,(H,18,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 750n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM118048
PNG
(CHEMBL599395 | US8637558, 76)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccc(cc2)-c2ccccc2)cc1
Show InChI InChI=1S/C23H17NO3S/c25-22-21(28-23(26)24-22)14-16-8-12-20(13-9-16)27-15-17-6-10-19(11-7-17)18-4-2-1-3-5-18/h1-14H,15H2,(H,24,25,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 814n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378644
PNG
(CHEMBL606032)
Show SMILES O=C1NC(=O)\C(N1)=C\c1ccc(OCCC2CCCCC2)cc1
Show InChI InChI=1S/C18H22N2O3/c21-17-16(19-18(22)20-17)12-14-6-8-15(9-7-14)23-11-10-13-4-2-1-3-5-13/h6-9,12-13H,1-5,10-11H2,(H2,19,20,21,22)/b16-12-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 865n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+]


(Homo sapiens (Human))
BDBM50378632
PNG
(CHEMBL601089 | US8637558, 25)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccco2)cc1
Show InChI InChI=1S/C15H11NO4S/c17-14-13(21-15(18)16-14)8-10-3-5-11(6-4-10)20-9-12-2-1-7-19-12/h1-8H,9H2,(H,16,17,18)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 893n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometry


Bioorg Med Chem 18: 1428-33 (2010)


Article DOI: 10.1016/j.bmc.2010.01.016
BindingDB Entry DOI: 10.7270/Q2Z0393H
More data for this
Ligand-Target Pair
P-glycoprotein 1


(Homo sapiens (Human))
BDBM50420208
PNG
(CHEMBL370963)
Show SMILES COc1cc(cc(OC)c1OC)-c1cc(=O)c2c(OC)c(OC)c(OC)cc2o1
Show InChI InChI=1S/C21H22O8/c1-23-15-7-11(8-16(24-2)19(15)26-4)13-9-12(22)18-14(29-13)10-17(25-3)20(27-5)21(18)28-6/h7-10H,1-6H3
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 900n/an/an/an/an/an/a



Chosun University

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cells


Biochem Biophys Res Commun 320: 672-9 (2004)


Article DOI: 10.1016/j.bbrc.2004.06.020
BindingDB Entry DOI: 10.7270/Q2891748
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 192 total )  |  Next  |  Last  >>
Jump to: