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Compile Data Set for Download or QSAR

Found 36 hits from Clinic of Nuclear Medicine   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50373710
PNG
(CHEMBL270408)
Show SMILES COc1ccccc1N1CCN(Cc2cccc(OCCF)c2)CC1
Show InChI InChI=1S/C20H25FN2O2/c1-24-20-8-3-2-7-19(20)23-12-10-22(11-13-23)16-17-5-4-6-18(15-17)25-14-9-21/h2-8,15H,9-14,16H2,1H3
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57n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human dopamine D2 long receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50373715
PNG
(CHEMBL271513)
Show SMILES COc1ccccc1N1CCN(Cc2ccc(OCCF)cc2)CC1
Show InChI InChI=1S/C20H25FN2O2/c1-24-20-5-3-2-4-19(20)23-13-11-22(12-14-23)16-17-6-8-18(9-7-17)25-15-10-21/h2-9H,10-16H2,1H3
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77n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human D3 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50373714
PNG
(CHEMBL270406)
Show SMILES COc1cc(CN2CCN(CC2)c2ccccc2OC)c(OCCF)cc1OC
Show InChI InChI=1S/C22H29FN2O4/c1-26-19-7-5-4-6-18(19)25-11-9-24(10-12-25)16-17-14-21(27-2)22(28-3)15-20(17)29-13-8-23/h4-7,14-15H,8-13,16H2,1-3H3
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94n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human dopamine D2 long receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
5-HT2


(PIG)
BDBM50373711
PNG
(CHEMBL256637)
Show SMILES COc1cc(CN2CCN(CC2)c2ccc(Cl)cc2)c(OCCF)cc1OC
Show InChI InChI=1S/C21H26ClFN2O3/c1-26-20-13-16(19(28-12-7-23)14-21(20)27-2)15-24-8-10-25(11-9-24)18-5-3-17(22)4-6-18/h3-6,13-14H,7-12,15H2,1-2H3
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100n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from pig cortical membrane 5HT2 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50373715
PNG
(CHEMBL271513)
Show SMILES COc1ccccc1N1CCN(Cc2ccc(OCCF)cc2)CC1
Show InChI InChI=1S/C20H25FN2O2/c1-24-20-5-3-2-4-19(20)23-13-11-22(12-14-23)16-17-6-8-18(9-7-17)25-15-10-21/h2-9H,10-16H2,1H3
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120n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human dopamine D2 long receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50373710
PNG
(CHEMBL270408)
Show SMILES COc1ccccc1N1CCN(Cc2cccc(OCCF)c2)CC1
Show InChI InChI=1S/C20H25FN2O2/c1-24-20-8-3-2-7-19(20)23-12-10-22(11-13-23)16-17-5-4-6-18(15-17)25-14-9-21/h2-8,15H,9-14,16H2,1H3
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270n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human D3 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
5-HT2


(PIG)
BDBM50373714
PNG
(CHEMBL270406)
Show SMILES COc1cc(CN2CCN(CC2)c2ccccc2OC)c(OCCF)cc1OC
Show InChI InChI=1S/C22H29FN2O4/c1-26-19-7-5-4-6-18(19)25-11-9-24(10-12-25)16-17-14-21(27-2)22(28-3)15-20(17)29-13-8-23/h4-7,14-15H,8-13,16H2,1-3H3
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280n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from pig cortical membrane 5HT2 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50373708
PNG
(CHEMBL256492)
Show SMILES COc1cc(CN2CCN(CC2)c2ccccc2OC)ccc1OCCF
Show InChI InChI=1S/C21H27FN2O3/c1-25-19-6-4-3-5-18(19)24-12-10-23(11-13-24)16-17-7-8-20(27-14-9-22)21(15-17)26-2/h3-8,15H,9-14,16H2,1-2H3
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310n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human dopamine D2 long receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50373714
PNG
(CHEMBL270406)
Show SMILES COc1cc(CN2CCN(CC2)c2ccccc2OC)c(OCCF)cc1OC
Show InChI InChI=1S/C22H29FN2O4/c1-26-19-7-5-4-6-18(19)25-11-9-24(10-12-25)16-17-14-21(27-2)22(28-3)15-20(17)29-13-8-23/h4-7,14-15H,8-13,16H2,1-3H3
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330n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human D3 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50373712
PNG
(CHEMBL255163)
Show SMILES FCCOc1cccc(CN2CCN(CC2)c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C19H22ClFN2O/c20-17-4-6-18(7-5-17)23-11-9-22(10-12-23)15-16-2-1-3-19(14-16)24-13-8-21/h1-7,14H,8-13,15H2
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590n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human dopamine D2 long receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50373711
PNG
(CHEMBL256637)
Show SMILES COc1cc(CN2CCN(CC2)c2ccc(Cl)cc2)c(OCCF)cc1OC
Show InChI InChI=1S/C21H26ClFN2O3/c1-26-20-13-16(19(28-12-7-23)14-21(20)27-2)15-24-8-10-25(11-9-24)18-5-3-17(22)4-6-18/h3-6,13-14H,7-12,15H2,1-2H3
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760n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human dopamine D2 long receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
5-HT2


(PIG)
BDBM50373713
PNG
(CHEMBL404888)
Show SMILES COc1cc(CN2CCN(CC2)c2ccc(Cl)cc2)ccc1OCCF
Show InChI InChI=1S/C20H24ClFN2O2/c1-25-20-14-16(2-7-19(20)26-13-8-22)15-23-9-11-24(12-10-23)18-5-3-17(21)4-6-18/h2-7,14H,8-13,15H2,1H3
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850n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from pig cortical membrane 5HT2 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
5-HT2


(PIG)
BDBM50102712
PNG
(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2
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900n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from pig cortical membrane 5HT2 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
5-HT2


(PIG)
BDBM50373712
PNG
(CHEMBL255163)
Show SMILES FCCOc1cccc(CN2CCN(CC2)c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C19H22ClFN2O/c20-17-4-6-18(7-5-17)23-11-9-22(10-12-23)15-16-2-1-3-19(14-16)24-13-8-21/h1-7,14H,8-13,15H2
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980n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from pig cortical membrane 5HT2 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50373709
PNG
(CHEMBL272073)
Show SMILES FCCOc1ccc(CN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C19H22ClFN2O/c20-17-3-5-18(6-4-17)23-12-10-22(11-13-23)15-16-1-7-19(8-2-16)24-14-9-21/h1-8H,9-15H2
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1.10E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human D3 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50373709
PNG
(CHEMBL272073)
Show SMILES FCCOc1ccc(CN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C19H22ClFN2O/c20-17-3-5-18(6-4-17)23-12-10-22(11-13-23)15-16-1-7-19(8-2-16)24-14-9-21/h1-8H,9-15H2
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1.10E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human dopamine D2 long receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50373712
PNG
(CHEMBL255163)
Show SMILES FCCOc1cccc(CN2CCN(CC2)c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C19H22ClFN2O/c20-17-4-6-18(7-5-17)23-11-9-22(10-12-23)15-16-2-1-3-19(14-16)24-13-8-21/h1-7,14H,8-13,15H2
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1.10E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human D3 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50373708
PNG
(CHEMBL256492)
Show SMILES COc1cc(CN2CCN(CC2)c2ccccc2OC)ccc1OCCF
Show InChI InChI=1S/C21H27FN2O3/c1-25-19-6-4-3-5-18(19)24-12-10-23(11-13-24)16-17-7-8-20(27-14-9-22)21(15-17)26-2/h3-8,15H,9-14,16H2,1-2H3
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1.10E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human D3 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine D1 receptor


(Sus scrofa)
BDBM50373709
PNG
(CHEMBL272073)
Show SMILES FCCOc1ccc(CN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C19H22ClFN2O/c20-17-3-5-18(6-4-17)23-12-10-22(11-13-23)15-16-1-7-19(8-2-16)24-14-9-21/h1-8H,9-15H2
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1.40E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to pig cortical membrane dopamine D1 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
5-HT2


(PIG)
BDBM50373709
PNG
(CHEMBL272073)
Show SMILES FCCOc1ccc(CN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C19H22ClFN2O/c20-17-3-5-18(6-4-17)23-12-10-22(11-13-23)15-16-1-7-19(8-2-16)24-14-9-21/h1-8H,9-15H2
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1.80E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from pig cortical membrane 5HT2 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
5-HT2


(PIG)
BDBM50373710
PNG
(CHEMBL270408)
Show SMILES COc1ccccc1N1CCN(Cc2cccc(OCCF)c2)CC1
Show InChI InChI=1S/C20H25FN2O2/c1-24-20-8-3-2-7-19(20)23-12-10-22(11-13-23)16-17-5-4-6-18(15-17)25-14-9-21/h2-8,15H,9-14,16H2,1H3
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1.90E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from pig cortical membrane 5HT2 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
5-HT2


(PIG)
BDBM50373708
PNG
(CHEMBL256492)
Show SMILES COc1cc(CN2CCN(CC2)c2ccccc2OC)ccc1OCCF
Show InChI InChI=1S/C21H27FN2O3/c1-25-19-6-4-3-5-18(19)24-12-10-23(11-13-24)16-17-7-8-20(27-14-9-22)21(15-17)26-2/h3-8,15H,9-14,16H2,1-2H3
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2.10E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from pig cortical membrane 5HT2 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50102712
PNG
(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2
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3.40E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human dopamine D2 long receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine D1 receptor


(Sus scrofa)
BDBM50373715
PNG
(CHEMBL271513)
Show SMILES COc1ccccc1N1CCN(Cc2ccc(OCCF)cc2)CC1
Show InChI InChI=1S/C20H25FN2O2/c1-24-20-5-3-2-4-19(20)23-13-11-22(12-14-23)16-17-6-8-18(9-7-17)25-15-10-21/h2-9H,10-16H2,1H3
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3.40E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to pig cortical membrane dopamine D1 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine D1 receptor


(Sus scrofa)
BDBM50373711
PNG
(CHEMBL256637)
Show SMILES COc1cc(CN2CCN(CC2)c2ccc(Cl)cc2)c(OCCF)cc1OC
Show InChI InChI=1S/C21H26ClFN2O3/c1-26-20-13-16(19(28-12-7-23)14-21(20)27-2)15-24-8-10-25(11-9-24)18-5-3-17(22)4-6-18/h3-6,13-14H,7-12,15H2,1-2H3
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3.50E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to pig cortical membrane dopamine D1 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50373711
PNG
(CHEMBL256637)
Show SMILES COc1cc(CN2CCN(CC2)c2ccc(Cl)cc2)c(OCCF)cc1OC
Show InChI InChI=1S/C21H26ClFN2O3/c1-26-20-13-16(19(28-12-7-23)14-21(20)27-2)15-24-8-10-25(11-9-24)18-5-3-17(22)4-6-18/h3-6,13-14H,7-12,15H2,1-2H3
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3.90E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human D3 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50373713
PNG
(CHEMBL404888)
Show SMILES COc1cc(CN2CCN(CC2)c2ccc(Cl)cc2)ccc1OCCF
Show InChI InChI=1S/C20H24ClFN2O2/c1-25-20-14-16(2-7-19(20)26-13-8-22)15-23-9-11-24(12-10-23)18-5-3-17(21)4-6-18/h2-7,14H,8-13,15H2,1H3
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4.90E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human D3 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine D1 receptor


(Sus scrofa)
BDBM50373712
PNG
(CHEMBL255163)
Show SMILES FCCOc1cccc(CN2CCN(CC2)c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C19H22ClFN2O/c20-17-4-6-18(7-5-17)23-11-9-22(10-12-23)15-16-2-1-3-19(14-16)24-13-8-21/h1-7,14H,8-13,15H2
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5.10E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to pig cortical membrane dopamine D1 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine D1 receptor


(Sus scrofa)
BDBM50373710
PNG
(CHEMBL270408)
Show SMILES COc1ccccc1N1CCN(Cc2cccc(OCCF)c2)CC1
Show InChI InChI=1S/C20H25FN2O2/c1-24-20-8-3-2-7-19(20)23-12-10-22(11-13-23)16-17-5-4-6-18(15-17)25-14-9-21/h2-8,15H,9-14,16H2,1H3
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5.20E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to pig cortical membrane dopamine D1 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50102712
PNG
(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2
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5.30E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human D3 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
5-HT2


(PIG)
BDBM50373715
PNG
(CHEMBL271513)
Show SMILES COc1ccccc1N1CCN(Cc2ccc(OCCF)cc2)CC1
Show InChI InChI=1S/C20H25FN2O2/c1-24-20-5-3-2-4-19(20)23-13-11-22(12-14-23)16-17-6-8-18(9-7-17)25-15-10-21/h2-9H,10-16H2,1H3
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5.40E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from pig cortical membrane 5HT2 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine D1 receptor


(Sus scrofa)
BDBM50373708
PNG
(CHEMBL256492)
Show SMILES COc1cc(CN2CCN(CC2)c2ccccc2OC)ccc1OCCF
Show InChI InChI=1S/C21H27FN2O3/c1-25-19-6-4-3-5-18(19)24-12-10-23(11-13-24)16-17-7-8-20(27-14-9-22)21(15-17)26-2/h3-8,15H,9-14,16H2,1-2H3
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5.40E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to pig cortical membrane dopamine D1 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine D1 receptor


(Sus scrofa)
BDBM50102712
PNG
(2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2
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5.50E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to pig cortical membrane dopamine D1 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine D1 receptor


(Sus scrofa)
BDBM50373713
PNG
(CHEMBL404888)
Show SMILES COc1cc(CN2CCN(CC2)c2ccc(Cl)cc2)ccc1OCCF
Show InChI InChI=1S/C20H24ClFN2O2/c1-25-20-14-16(2-7-19(20)26-13-8-22)15-23-9-11-24(12-10-23)18-5-3-17(21)4-6-18/h2-7,14H,8-13,15H2,1H3
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5.70E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to pig cortical membrane dopamine D1 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
Dopamine D1 receptor


(Sus scrofa)
BDBM50373714
PNG
(CHEMBL270406)
Show SMILES COc1cc(CN2CCN(CC2)c2ccccc2OC)c(OCCF)cc1OC
Show InChI InChI=1S/C22H29FN2O4/c1-26-19-7-5-4-6-18(19)25-11-9-24(10-12-25)16-17-14-21(27-2)22(28-3)15-20(17)29-13-8-23/h4-7,14-15H,8-13,16H2,1-3H3
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6.80E+3n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to pig cortical membrane dopamine D1 receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50373713
PNG
(CHEMBL404888)
Show SMILES COc1cc(CN2CCN(CC2)c2ccc(Cl)cc2)ccc1OCCF
Show InChI InChI=1S/C20H24ClFN2O2/c1-25-20-14-16(2-7-19(20)26-13-8-22)15-23-9-11-24(12-10-23)18-5-3-17(21)4-6-18/h2-7,14H,8-13,15H2,1H3
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2.10E+4n/an/an/an/an/an/an/an/a



Clinic of Nuclear Medicine

Curated by ChEMBL


Assay Description
Binding affinity to human dopamine D2 long receptor


Bioorg Med Chem Lett 18: 983-8 (2008)


Article DOI: 10.1016/j.bmcl.2007.12.026
BindingDB Entry DOI: 10.7270/Q2B56KMT
More data for this
Ligand-Target Pair