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Compile Data Set for Download or QSAR

Found 32 hits from DaQing Oil Field General Hospital   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117862
PNG
(CHEMBL3614035)
Show SMILES Fc1ccc(cc1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8FN7S/c14-10-3-1-8(2-4-10)11-7-22-13(16-11)21-6-9(5-15-21)12-17-19-20-18-12/h1-7H,(H,17,18,19,20)
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n/an/a 240n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117861
PNG
(CHEMBL3614036)
Show SMILES Fc1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8FN7S/c14-10-3-1-2-8(4-10)11-7-22-13(16-11)21-6-9(5-15-21)12-17-19-20-18-12/h1-7H,(H,17,18,19,20)
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n/an/a 1.45E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117860
PNG
(CHEMBL3614037)
Show SMILES Fc1ccccc1-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8FN7S/c14-10-4-2-1-3-9(10)11-7-22-13(16-11)21-6-8(5-15-21)12-17-19-20-18-12/h1-7H,(H,17,18,19,20)
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n/an/a 1.89E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117862
PNG
(CHEMBL3614035)
Show SMILES Fc1ccc(cc1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8FN7S/c14-10-3-1-8(2-4-10)11-7-22-13(16-11)21-6-9(5-15-21)12-17-19-20-18-12/h1-7H,(H,17,18,19,20)
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n/an/a 2.34E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117865
PNG
(CHEMBL3614033)
Show SMILES Clc1ccc(cc1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8ClN7S/c14-10-3-1-8(2-4-10)11-7-22-13(16-11)21-6-9(5-15-21)12-17-19-20-18-12/h1-7H,(H,17,18,19,20)
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n/an/a 2.45E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117864
PNG
(CHEMBL3614032)
Show SMILES Clc1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8ClN7S/c14-10-3-1-2-8(4-10)11-7-22-13(16-11)21-6-9(5-15-21)12-17-19-20-18-12/h1-7H,(H,17,18,19,20)
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n/an/a 2.99E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117863
PNG
(CHEMBL3614034)
Show SMILES Clc1ccccc1-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8ClN7S/c14-10-4-2-1-3-9(10)11-7-22-13(16-11)21-6-8(5-15-21)12-17-19-20-18-12/h1-7H,(H,17,18,19,20)
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n/an/a 3.62E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117865
PNG
(CHEMBL3614033)
Show SMILES Clc1ccc(cc1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8ClN7S/c14-10-3-1-8(2-4-10)11-7-22-13(16-11)21-6-9(5-15-21)12-17-19-20-18-12/h1-7H,(H,17,18,19,20)
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n/an/a 3.83E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117861
PNG
(CHEMBL3614036)
Show SMILES Fc1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8FN7S/c14-10-3-1-2-8(4-10)11-7-22-13(16-11)21-6-9(5-15-21)12-17-19-20-18-12/h1-7H,(H,17,18,19,20)
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n/an/a 4.65E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117860
PNG
(CHEMBL3614037)
Show SMILES Fc1ccccc1-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8FN7S/c14-10-4-2-1-3-9(10)11-7-22-13(16-11)21-6-8(5-15-21)12-17-19-20-18-12/h1-7H,(H,17,18,19,20)
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n/an/a 4.72E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117864
PNG
(CHEMBL3614032)
Show SMILES Clc1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8ClN7S/c14-10-3-1-2-8(4-10)11-7-22-13(16-11)21-6-9(5-15-21)12-17-19-20-18-12/h1-7H,(H,17,18,19,20)
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n/an/a 5.01E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117863
PNG
(CHEMBL3614034)
Show SMILES Clc1ccccc1-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8ClN7S/c14-10-4-2-1-3-9(10)11-7-22-13(16-11)21-6-8(5-15-21)12-17-19-20-18-12/h1-7H,(H,17,18,19,20)
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n/an/a 5.92E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117859
PNG
(CHEMBL3614038)
Show SMILES [O-][N+](=O)c1ccc(cc1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8N8O2S/c22-21(23)10-3-1-8(2-4-10)11-7-24-13(15-11)20-6-9(5-14-20)12-16-18-19-17-12/h1-7H,(H,16,17,18,19)
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n/an/a 6.23E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117858
PNG
(CHEMBL3614039)
Show SMILES [O-][N+](=O)c1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8N8O2S/c22-21(23)10-3-1-2-8(4-10)11-7-24-13(15-11)20-6-9(5-14-20)12-16-18-19-17-12/h1-7H,(H,16,17,18,19)
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n/an/a 6.89E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117859
PNG
(CHEMBL3614038)
Show SMILES [O-][N+](=O)c1ccc(cc1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8N8O2S/c22-21(23)10-3-1-8(2-4-10)11-7-24-13(15-11)20-6-9(5-14-20)12-16-18-19-17-12/h1-7H,(H,16,17,18,19)
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n/an/a 7.27E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117857
PNG
(CHEMBL3614040)
Show SMILES [O-][N+](=O)c1ccccc1-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8N8O2S/c22-21(23)11-4-2-1-3-9(11)10-7-24-13(15-10)20-6-8(5-14-20)12-16-18-19-17-12/h1-7H,(H,16,17,18,19)
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n/an/a 7.43E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117856
PNG
(CHEMBL3614031)
Show SMILES Cc1ccc(cc1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N7S/c1-9-2-4-10(5-3-9)12-8-22-14(16-12)21-7-11(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)
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n/an/a 8.15E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117858
PNG
(CHEMBL3614039)
Show SMILES [O-][N+](=O)c1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8N8O2S/c22-21(23)10-3-1-2-8(4-10)11-7-24-13(15-11)20-6-9(5-14-20)12-16-18-19-17-12/h1-7H,(H,16,17,18,19)
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n/an/a 8.54E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117870
PNG
(CHEMBL3614041)
Show SMILES Cc1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N7S/c1-9-3-2-4-10(5-9)12-8-22-14(16-12)21-7-11(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)
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n/an/a 9.12E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117869
PNG
(CHEMBL3614042)
Show SMILES Cc1ccccc1-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N7S/c1-9-4-2-3-5-11(9)12-8-22-14(16-12)21-7-10(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)
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n/an/a 9.89E+3n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117857
PNG
(CHEMBL3614040)
Show SMILES [O-][N+](=O)c1ccccc1-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C13H8N8O2S/c22-21(23)11-4-2-1-3-9(11)10-7-24-13(15-10)20-6-8(5-14-20)12-16-18-19-17-12/h1-7H,(H,16,17,18,19)
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n/an/a 1.02E+4n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50016980
PNG
(6-(4-(3,4-dimethoxybenzoyl)piperazin-1-yl)-3,4-dih...)
Show SMILES COc1ccc(cc1OC)C(=O)N1CCN(CC1)c1ccc2NC(=O)CCc2c1
Show InChI InChI=1S/C22H25N3O4/c1-28-19-7-3-16(14-20(19)29-2)22(27)25-11-9-24(10-12-25)17-5-6-18-15(13-17)4-8-21(26)23-18/h3,5-7,13-14H,4,8-12H2,1-2H3,(H,23,26)
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n/an/a 1.12E+4n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117868
PNG
(CHEMBL3614043)
Show SMILES COc1ccc(cc1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N7OS/c1-22-11-4-2-9(3-5-11)12-8-23-14(16-12)21-7-10(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)
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n/an/a 1.34E+4n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117870
PNG
(CHEMBL3614041)
Show SMILES Cc1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N7S/c1-9-3-2-4-10(5-9)12-8-22-14(16-12)21-7-11(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)
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n/an/a 1.45E+4n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50016980
PNG
(6-(4-(3,4-dimethoxybenzoyl)piperazin-1-yl)-3,4-dih...)
Show SMILES COc1ccc(cc1OC)C(=O)N1CCN(CC1)c1ccc2NC(=O)CCc2c1
Show InChI InChI=1S/C22H25N3O4/c1-28-19-7-3-16(14-20(19)29-2)22(27)25-11-9-24(10-12-25)17-5-6-18-15(13-17)4-8-21(26)23-18/h3,5-7,13-14H,4,8-12H2,1-2H3,(H,23,26)
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n/an/a 1.45E+4n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117867
PNG
(CHEMBL3614044)
Show SMILES COc1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N7OS/c1-22-11-4-2-3-9(5-11)12-8-23-14(16-12)21-7-10(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)
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n/an/a 1.46E+4n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
Phosphodiesterase 3 (PDE3)


(Homo sapiens (human))
BDBM50117866
PNG
(CHEMBL3614045)
Show SMILES COc1ccccc1-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N7OS/c1-22-12-5-3-2-4-10(12)11-8-23-14(16-11)21-7-9(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)
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n/an/a 1.64E+4n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3A using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117869
PNG
(CHEMBL3614042)
Show SMILES Cc1ccccc1-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N7S/c1-9-4-2-3-5-11(9)12-8-22-14(16-12)21-7-10(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)
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n/an/a 1.66E+4n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117856
PNG
(CHEMBL3614031)
Show SMILES Cc1ccc(cc1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N7S/c1-9-2-4-10(5-3-9)12-8-22-14(16-12)21-7-11(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)
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n/an/a 1.67E+4n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117867
PNG
(CHEMBL3614044)
Show SMILES COc1cccc(c1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N7OS/c1-22-11-4-2-3-9(5-11)12-8-23-14(16-12)21-7-10(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)
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n/an/a 2.51E+4n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117868
PNG
(CHEMBL3614043)
Show SMILES COc1ccc(cc1)-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N7OS/c1-22-11-4-2-9(3-5-11)12-8-23-14(16-12)21-7-10(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)
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n/an/a 2.56E+4n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase B


(Homo sapiens (human))
BDBM50117866
PNG
(CHEMBL3614045)
Show SMILES COc1ccccc1-c1csc(n1)-n1cc(cn1)-c1nnn[nH]1
Show InChI InChI=1S/C14H11N7OS/c1-22-12-5-3-2-4-10(12)11-8-23-14(16-11)21-7-9(6-15-21)13-17-19-20-18-13/h2-8H,1H3,(H,17,18,19,20)
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n/an/a 2.80E+4n/an/an/an/an/an/a



DaQing Oil Field General Hospital

Curated by ChEMBL


Assay Description
Inhibition of human PDE3B using FAM-cAMP by fluorescence polarization assay


Bioorg Med Chem 23: 6111-7 (2015)


Article DOI: 10.1016/j.bmc.2015.08.002
BindingDB Entry DOI: 10.7270/Q2HT2R46
More data for this
Ligand-Target Pair