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Compile Data Set for Download or QSAR

Found 27 hits from Daiichi Pharmaceutical Co., Ltd   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214997
PNG
(CHEMBL439391 | trans-N-(2-(5-chloro-1H-indole-2-ca...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCCC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C24H28ClN5O2S/c1-30-10-9-19-21(13-30)33-24(29-19)23(32)28-18-6-4-2-3-5-17(18)27-22(31)20-12-14-11-15(25)7-8-16(14)26-20/h7-8,11-12,17-18,26H,2-6,9-10,13H2,1H3,(H,27,31)(H,28,32)/t17-,18-/m1/s1
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n/an/a 11.3n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214983
PNG
(CHEMBL391805 | N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C23H26ClN5O2S/c1-29-9-8-18-20(12-29)32-23(28-18)22(31)27-17-5-3-2-4-16(17)26-21(30)19-11-13-10-14(24)6-7-15(13)25-19/h6-7,10-11,16-17,25H,2-5,8-9,12H2,1H3,(H,26,30)(H,27,31)/t16-,17-/m1/s1
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n/an/a 13n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214995
PNG
(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C23H26ClN5O2S/c1-29-9-8-18-20(12-29)32-23(28-18)22(31)27-17-5-3-2-4-16(17)26-21(30)19-11-13-10-14(24)6-7-15(13)25-19/h6-7,10-11,16-17,25H,2-5,8-9,12H2,1H3,(H,26,30)(H,27,31)/t16-,17+/m0/s1
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n/an/a 16n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214995
PNG
(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C23H26ClN5O2S/c1-29-9-8-18-20(12-29)32-23(28-18)22(31)27-17-5-3-2-4-16(17)26-21(30)19-11-13-10-14(24)6-7-15(13)25-19/h6-7,10-11,16-17,25H,2-5,8-9,12H2,1H3,(H,26,30)(H,27,31)/t16-,17+/m0/s1
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n/an/a 41n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214988
PNG
(CHEMBL393873 | trans-N-(2-(5-chloro-1H-indole-2-ca...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C22H24ClN5O2S/c1-28-8-7-17-19(11-28)31-22(27-17)21(30)26-16-4-2-3-15(16)25-20(29)18-10-12-9-13(23)5-6-14(12)24-18/h5-6,9-10,15-16,24H,2-4,7-8,11H2,1H3,(H,25,29)(H,26,30)/t15-,16-/m1/s1
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n/an/a 86n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50214986
PNG
(CHEMBL247732 | N-((1S,2R)-2-(5-chloro-1H-indole-2-...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@H]1CCCC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C23H26ClN5O2S/c1-29-9-8-18-20(12-29)32-23(28-18)22(31)27-17-5-3-2-4-16(17)26-21(30)19-11-13-10-14(24)6-7-15(13)25-19/h6-7,10-11,16-17,25H,2-5,8-9,12H2,1H3,(H,26,30)(H,27,31)/t16-,17+/m1/s1
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n/an/a>100n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 2a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214985
PNG
(CHEMBL391804 | cis-N-(2-(5-chloro-1H-indole-2-carb...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCC[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C22H24ClN5O2S/c1-28-8-7-17-19(11-28)31-22(27-17)21(30)26-16-4-2-3-15(16)25-20(29)18-10-12-9-13(23)5-6-14(12)24-18/h5-6,9-10,15-16,24H,2-4,7-8,11H2,1H3,(H,25,29)(H,26,30)/t15-,16+/m0/s1
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n/an/a 118n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214987
PNG
(CHEMBL245679 | cis-N-(2-(5-chloro-1H-indole-2-carb...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCCC[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C24H28ClN5O2S/c1-30-10-9-19-21(13-30)33-24(29-19)23(32)28-18-6-4-2-3-5-17(18)27-22(31)20-12-14-11-15(25)7-8-16(14)26-20/h7-8,11-12,17-18,26H,2-6,9-10,13H2,1H3,(H,27,31)(H,28,32)/t17-,18+/m0/s1
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n/an/a 175n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214998
PNG
(CHEMBL391593 | cis-N-(2-(5-chloro-1H-indole-2-carb...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1C[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C20H20ClN5O2S/c1-26-5-4-13-17(9-26)29-20(25-13)19(28)24-15-8-14(15)23-18(27)16-7-10-6-11(21)2-3-12(10)22-16/h2-3,6-7,14-15,22H,4-5,8-9H2,1H3,(H,23,27)(H,24,28)/t14-,15+/m0/s1
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n/an/a 187n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214999
PNG
(CHEMBL247525 | cis-N-(2-(5-chloro-1H-indole-2-carb...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CC[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C21H22ClN5O2S/c1-27-7-6-16-18(10-27)30-21(26-16)20(29)25-15-5-4-14(15)24-19(28)17-9-11-8-12(22)2-3-13(11)23-17/h2-3,8-9,14-15,23H,4-7,10H2,1H3,(H,24,28)(H,25,29)/t14-,15+/m0/s1
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n/an/a 265n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214992
PNG
(CHEMBL246915 | cis-N-(2-(5-chloro-1H-indole-2-sulf...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1C[C@@H]1NS(=O)(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C19H20ClN5O3S2/c1-25-5-4-13-16(9-25)29-19(23-13)18(26)22-14-8-15(14)24-30(27,28)17-7-10-6-11(20)2-3-12(10)21-17/h2-3,6-7,14-15,21,24H,4-5,8-9H2,1H3,(H,22,26)/t14-,15+/m1/s1
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n/an/a 270n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214986
PNG
(CHEMBL247732 | N-((1S,2R)-2-(5-chloro-1H-indole-2-...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@H]1CCCC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C23H26ClN5O2S/c1-29-9-8-18-20(12-29)32-23(28-18)22(31)27-17-5-3-2-4-16(17)26-21(30)19-11-13-10-14(24)6-7-15(13)25-19/h6-7,10-11,16-17,25H,2-5,8-9,12H2,1H3,(H,26,30)(H,27,31)/t16-,17+/m1/s1
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n/an/a 753n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214993
PNG
(CHEMBL247535 | cis-N-(2-(5-chloro-1H-indole-2-carb...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCCCC[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C25H30ClN5O2S/c1-31-11-10-20-22(14-31)34-25(30-20)24(33)29-19-7-5-3-2-4-6-18(19)28-23(32)21-13-15-12-16(26)8-9-17(15)27-21/h8-9,12-13,18-19,27H,2-7,10-11,14H2,1H3,(H,28,32)(H,29,33)/t18-,19+/m0/s1
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n/an/a>1.40E+3n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214990
PNG
(CHEMBL391594 | trans-N-(2-(5-chloro-1H-indole-2-ca...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C21H22ClN5O2S/c1-27-7-6-16-18(10-27)30-21(26-16)20(29)25-15-5-4-14(15)24-19(28)17-9-11-8-12(22)2-3-13(11)23-17/h2-3,8-9,14-15,23H,4-7,10H2,1H3,(H,24,28)(H,25,29)/t14-,15-/m1/s1
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n/an/a 2.00E+3n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50214995
PNG
(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C23H26ClN5O2S/c1-29-9-8-18-20(12-29)32-23(28-18)22(31)27-17-5-3-2-4-16(17)26-21(30)19-11-13-10-14(24)6-7-15(13)25-19/h6-7,10-11,16-17,25H,2-5,8-9,12H2,1H3,(H,26,30)(H,27,31)/t16-,17+/m0/s1
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n/an/a 2.60E+3n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 2a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50215000
PNG
(CHEMBL247117 | cis-N-(2-(5-chloro-1H-indole-2-sulf...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCC[C@@H]1NS(=O)(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C21H24ClN5O3S2/c1-27-8-7-17-18(11-27)31-21(25-17)20(28)24-15-3-2-4-16(15)26-32(29,30)19-10-12-9-13(22)5-6-14(12)23-19/h5-6,9-10,15-16,23,26H,2-4,7-8,11H2,1H3,(H,24,28)/t15-,16+/m1/s1
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n/an/a 3.20E+3n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214996
PNG
(CHEMBL247118 | cis-N-(2-(5-chloro-1H-indole-2-sulf...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCC[C@@H]1NS(=O)(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C22H26ClN5O3S2/c1-28-9-8-18-19(12-28)32-22(26-18)21(29)25-16-4-2-3-5-17(16)27-33(30,31)20-11-13-10-14(23)6-7-15(13)24-20/h6-7,10-11,16-17,24,27H,2-5,8-9,12H2,1H3,(H,25,29)/t16-,17+/m1/s1
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n/an/a 4.40E+3n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50214995
PNG
(CHEMBL245678 | N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C23H26ClN5O2S/c1-29-9-8-18-20(12-29)32-23(28-18)22(31)27-17-5-3-2-4-16(17)26-21(30)19-11-13-10-14(24)6-7-15(13)25-19/h6-7,10-11,16-17,25H,2-5,8-9,12H2,1H3,(H,26,30)(H,27,31)/t16-,17+/m0/s1
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n/an/a 4.50E+3n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 2a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214994
PNG
(CHEMBL247536 | trans-N-(2-(5-chloro-1H-indole-2-ca...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCCCC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C25H30ClN5O2S/c1-31-11-10-20-22(14-31)34-25(30-20)24(33)29-19-7-5-3-2-4-6-18(19)28-23(32)21-13-15-12-16(26)8-9-17(15)27-21/h8-9,12-13,18-19,27H,2-7,10-11,14H2,1H3,(H,28,32)(H,29,33)/t18-,19-/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214991
PNG
(CHEMBL393671 | trans-N-(2-(5-chloro-1H-indole-2-su...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCC[C@H]1NS(=O)(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C21H24ClN5O3S2/c1-27-8-7-17-18(11-27)31-21(25-17)20(28)24-15-3-2-4-16(15)26-32(29,30)19-10-12-9-13(22)5-6-14(12)23-19/h5-6,9-10,15-16,23,26H,2-4,7-8,11H2,1H3,(H,24,28)/t15-,16-/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214989
PNG
(CHEMBL247321 | trans-N-(2-(5-chloro-1H-indole-2-su...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCC[C@H]1NS(=O)(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C22H26ClN5O3S2/c1-28-9-8-18-19(12-28)32-22(26-18)21(29)25-16-4-2-3-5-17(16)27-33(30,31)20-11-13-10-14(23)6-7-15(13)24-20/h6-7,10-11,16-17,24,27H,2-5,8-9,12H2,1H3,(H,25,29)/t16-,17-/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50215001
PNG
(CHEMBL247116 | trans-N-(2-(5-chloro-1H-indole-2-su...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1C[C@H]1NS(=O)(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C19H20ClN5O3S2/c1-25-5-4-13-16(9-25)29-19(23-13)18(26)22-14-8-15(14)24-30(27,28)17-7-10-6-11(20)2-3-12(10)21-17/h2-3,6-7,14-15,21,24H,4-5,8-9H2,1H3,(H,22,26)/t14-,15-/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50214984
PNG
(CHEMBL247322 | trans-N-(2-(5-chloro-1H-indole-2-ca...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1C[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C20H20ClN5O2S/c1-26-5-4-13-17(9-26)29-20(25-13)19(28)24-15-8-14(15)23-18(27)16-7-10-6-11(21)2-3-12(10)22-16/h2-3,6-7,14-15,22H,4-5,8-9H2,1H3,(H,23,27)(H,24,28)/t14-,15-/m1/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50214985
PNG
(CHEMBL391804 | cis-N-(2-(5-chloro-1H-indole-2-carb...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCC[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C22H24ClN5O2S/c1-28-8-7-17-19(11-28)31-22(27-17)21(30)26-16-4-2-3-15(16)25-20(29)18-10-12-9-13(23)5-6-14(12)24-18/h5-6,9-10,15-16,24H,2-4,7-8,11H2,1H3,(H,25,29)(H,26,30)/t15-,16+/m0/s1
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n/an/a 2.70E+4n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 2a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50214983
PNG
(CHEMBL391805 | N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C23H26ClN5O2S/c1-29-9-8-18-20(12-29)32-23(28-18)22(31)27-17-5-3-2-4-16(17)26-21(30)19-11-13-10-14(24)6-7-15(13)25-19/h6-7,10-11,16-17,25H,2-5,8-9,12H2,1H3,(H,26,30)(H,27,31)/t16-,17-/m1/s1
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n/an/a 2.90E+4n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 2a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50214988
PNG
(CHEMBL393873 | trans-N-(2-(5-chloro-1H-indole-2-ca...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C22H24ClN5O2S/c1-28-8-7-17-19(11-28)31-22(27-17)21(30)26-16-4-2-3-15(16)25-20(29)18-10-12-9-13(23)5-6-14(12)24-18/h5-6,9-10,15-16,24H,2-4,7-8,11H2,1H3,(H,25,29)(H,26,30)/t15-,16-/m1/s1
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n/an/a 3.60E+4n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 2a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50214997
PNG
(CHEMBL439391 | trans-N-(2-(5-chloro-1H-indole-2-ca...)
Show SMILES CN1CCc2nc(sc2C1)C(=O)N[C@@H]1CCCCC[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C24H28ClN5O2S/c1-30-10-9-19-21(13-30)33-24(29-19)23(32)28-18-6-4-2-3-5-17(18)27-22(31)20-12-14-11-15(25)7-8-16(14)26-20/h7-8,11-12,17-18,26H,2-6,9-10,13H2,1H3,(H,27,31)(H,28,32)/t17-,18-/m1/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Daiichi Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human factor 2a after 10 seconds


Bioorg Med Chem Lett 17: 4683-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.068
BindingDB Entry DOI: 10.7270/Q2183660
More data for this
Ligand-Target Pair