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Found 234 hits from Dainippon Pharmaceutical Co., Ltd.   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50160807
PNG
(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Show SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1
Show InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
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3.98n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM22869
PNG
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Show SMILES CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3
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8.38n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM22869
PNG
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Show SMILES CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3
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8.66n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
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8.79n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50160807
PNG
(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Show SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1
Show InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
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14.8n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
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20.3n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
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26.8n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50160807
PNG
(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Show SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1
Show InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
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56.3n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
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59.9n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM22869
PNG
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Show SMILES CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3
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149n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Sigma-1 receptor


(Cavia porcellus (Guinea pig))
BDBM50160807
PNG
(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Show SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1
Show InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
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286n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM22869
PNG
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Show SMILES CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3
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875n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM50160807
PNG
(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Show SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1
Show InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
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2.30E+3n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
DOPAMINE


(RAT)
BDBM50160807
PNG
(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Show SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1
Show InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
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2.87E+3n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50160807
PNG
(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Show SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1
Show InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
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2.99E+3n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50160807
PNG
(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Show SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1
Show InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
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3.01E+3n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50160807
PNG
(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Show SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1
Show InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
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7.68E+3n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
GABA


()
BDBM50160807
PNG
(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Show SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1
Show InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) alpha-1)


(Rattus norvegicus (Rat))
BDBM50160807
PNG
(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Show SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1
Show InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
ADRB2


(Rattus norvegicus)
BDBM50160807
PNG
(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Show SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1
Show InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 264: 158-65 (1993)


BindingDB Entry DOI: 10.7270/Q2TH8K60
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50008612
PNG
(CHEMBL154588 | Sodium; 3-(2-mercaptomethyl-3-pheny...)
Show SMILES [O-]S(=O)(=O)c1cccc(NC(=O)C(CS)Cc2ccccc2)c1
Show InChI InChI=1S/C16H17NO4S2/c18-16(13(11-22)9-12-5-2-1-3-6-12)17-14-7-4-8-15(10-14)23(19,20)21/h1-8,10,13,22H,9,11H2,(H,17,18)(H,19,20,21)/p-1
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Article
PubMed
n/an/a 0.270n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against enkephalinase enzyme from rat.


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50008616
PNG
(CHEMBL157625 | Sodium; 2-(2-mercaptomethyl-3-pheny...)
Show SMILES [O-]S(=O)(=O)CCNC(=O)[C@@H](CS)Cc1ccccc1
Show InChI InChI=1S/C12H17NO4S2/c14-12(13-6-7-19(15,16)17)11(9-18)8-10-4-2-1-3-5-10/h1-5,11,18H,6-9H2,(H,13,14)(H,15,16,17)/p-1/t11-/m1/s1
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n/an/a 0.820n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against enkephalinase enzyme from rat.


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50008595
PNG
(CHEMBL351330 | Sodium; 4-(2-mercaptomethyl-4-methy...)
Show SMILES CC(C)CC(CS)C(=O)Nc1ccc(cc1)S([O-])(=O)=O
Show InChI InChI=1S/C13H19NO4S2/c1-9(2)7-10(8-19)13(15)14-11-3-5-12(6-4-11)20(16,17)18/h3-6,9-10,19H,7-8H2,1-2H3,(H,14,15)(H,16,17,18)/p-1
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n/an/a 0.900n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against enkephalinase enzyme from rat.


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50070574
PNG
(5-Bromo-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-...)
Show SMILES CCN1CCN(C)CC(C1)NC(=O)c1cc(Br)c(NC)nc1OC
Show InChI InChI=1S/C16H26BrN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)
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n/an/a 1n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor


Bioorg Med Chem Lett 8: 1551-4 (1999)


Article DOI: 10.1016/s0960-894x(98)00258-3
BindingDB Entry DOI: 10.7270/Q2CF9P7B
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50008602
PNG
(CHEMBL435444 | Sodium; 4-(2-mercaptomethyl-3-p-tol...)
Show SMILES Cc1ccc(CC(CS)C(=O)Nc2ccc(cc2)S([O-])(=O)=O)cc1
Show InChI InChI=1S/C17H19NO4S2/c1-12-2-4-13(5-3-12)10-14(11-23)17(19)18-15-6-8-16(9-7-15)24(20,21)22/h2-9,14,23H,10-11H2,1H3,(H,18,19)(H,20,21,22)/p-1
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Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against enkephalinase enzyme from rat.


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50070571
PNG
(5-Bromo-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl...)
Show SMILES CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Br)c(NC)nc1OC
Show InChI InChI=1S/C16H26BrN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m1/s1
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Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor


Bioorg Med Chem Lett 8: 1551-4 (1999)


Article DOI: 10.1016/s0960-894x(98)00258-3
BindingDB Entry DOI: 10.7270/Q2CF9P7B
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50070566
PNG
(5-Bromo-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-yl...)
Show SMILES CCN1CCN(C)C[C@@H](C1)NC(=O)c1cc(Br)c(NC)nc1OC
Show InChI InChI=1S/C16H26BrN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m0/s1
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Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor


Bioorg Med Chem Lett 8: 1551-4 (1999)


Article DOI: 10.1016/s0960-894x(98)00258-3
BindingDB Entry DOI: 10.7270/Q2CF9P7B
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50070565
PNG
(5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2...)
Show SMILES CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(NC)nc1OC
Show InChI InChI=1S/C16H26ClN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)
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n/an/a 1.30n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor


Bioorg Med Chem Lett 8: 1551-4 (1999)


Article DOI: 10.1016/s0960-894x(98)00258-3
BindingDB Entry DOI: 10.7270/Q2CF9P7B
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM85330
PNG
(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Show SMILES Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C
Show InChI InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3
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Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligand


Bioorg Med Chem Lett 8: 619-24 (1999)


Article DOI: 10.1016/s0960-894x(98)00078-x
BindingDB Entry DOI: 10.7270/Q25Q4WN6
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50008605
PNG
(CHEMBL157663 | Sodium; 2-(2-mercaptomethyl-3-pheny...)
Show SMILES [O-]S(=O)(=O)CCNC(=O)C(CS)Cc1ccccc1
Show InChI InChI=1S/C12H17NO4S2/c14-12(13-6-7-19(15,16)17)11(9-18)8-10-4-2-1-3-5-10/h1-5,11,18H,6-9H2,(H,13,14)(H,15,16,17)/p-1
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Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against enkephalinase enzyme from rat.


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50366571
PNG
(CHEMBL1788261)
Show SMILES CCN1CCN(C)C[C@@H](C1)NC(=O)c1cc(Cl)c(NC)cc1OC
Show InChI InChI=1S/C17H27ClN4O2/c1-5-22-7-6-21(3)10-12(11-22)20-17(23)13-8-14(18)15(19-2)9-16(13)24-4/h8-9,12,19H,5-7,10-11H2,1-4H3,(H,20,23)/t12-/m0/s1
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Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligand


Bioorg Med Chem Lett 8: 619-24 (1999)


Article DOI: 10.1016/s0960-894x(98)00078-x
BindingDB Entry DOI: 10.7270/Q25Q4WN6
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50070569
PNG
(5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-y...)
Show SMILES CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Cl)c(NC)nc1OC
Show InChI InChI=1S/C16H26ClN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m1/s1
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n/an/a 1.60n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor


Bioorg Med Chem Lett 8: 1551-4 (1999)


Article DOI: 10.1016/s0960-894x(98)00258-3
BindingDB Entry DOI: 10.7270/Q2CF9P7B
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50008590
PNG
(CHEMBL154774 | Sodium; 4-(2-mercaptomethyl-3-pheny...)
Show SMILES [O-]S(=O)(=O)c1ccc(NC(=O)C(CS)Cc2ccccc2)cc1
Show InChI InChI=1S/C16H17NO4S2/c18-16(13(11-22)10-12-4-2-1-3-5-12)17-14-6-8-15(9-7-14)23(19,20)21/h1-9,13,22H,10-11H2,(H,17,18)(H,19,20,21)/p-1
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Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against enkephalinase enzyme from rat.


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50069286
PNG
(5-Chloro-4-ethylamino-N-(1-ethyl-4-methyl-[1,4]dia...)
Show SMILES CCNc1cc(OC)c(cc1Cl)C(=O)NC1CN(C)CCN(CC)C1
Show InChI InChI=1S/C18H29ClN4O2/c1-5-20-16-10-17(25-4)14(9-15(16)19)18(24)21-13-11-22(3)7-8-23(6-2)12-13/h9-10,13,20H,5-8,11-12H2,1-4H3,(H,21,24)
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n/an/a 1.90n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligand


Bioorg Med Chem Lett 8: 619-24 (1999)


Article DOI: 10.1016/s0960-894x(98)00078-x
BindingDB Entry DOI: 10.7270/Q25Q4WN6
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50070573
PNG
(5-Chloro-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]dia...)
Show SMILES CCNc1nc(OC)c(cc1Cl)C(=O)NC1CN(C)CCN(CC)C1
Show InChI InChI=1S/C17H28ClN5O2/c1-5-19-15-14(18)9-13(17(21-15)25-4)16(24)20-12-10-22(3)7-8-23(6-2)11-12/h9,12H,5-8,10-11H2,1-4H3,(H,19,21)(H,20,24)
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n/an/a 2n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor


Bioorg Med Chem Lett 8: 1551-4 (1999)


Article DOI: 10.1016/s0960-894x(98)00258-3
BindingDB Entry DOI: 10.7270/Q2CF9P7B
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50070564
PNG
(5-Chloro-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-y...)
Show SMILES CCN1CCN(C)C[C@@H](C1)NC(=O)c1cc(Cl)c(NC)nc1OC
Show InChI InChI=1S/C16H26ClN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m0/s1
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Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor


Bioorg Med Chem Lett 8: 1551-4 (1999)


Article DOI: 10.1016/s0960-894x(98)00258-3
BindingDB Entry DOI: 10.7270/Q2CF9P7B
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50008603
PNG
((2-Mercaptomethyl-3-phenyl-propionylamino)-methane...)
Show SMILES OS(=O)(=O)CNC(=O)C(CS)Cc1ccccc1
Show InChI InChI=1S/C11H15NO4S2/c13-11(12-8-18(14,15)16)10(7-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,12,13)(H,14,15,16)
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n/an/a 2.20n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against enkephalinase enzyme from rat.


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50008591
PNG
(CHEMBL346587 | Sodium; 3-(2-mercaptomethyl-4-methy...)
Show SMILES CC(C)CC(CS)C(=O)Nc1cccc(c1)S([O-])(=O)=O
Show InChI InChI=1S/C13H19NO4S2/c1-9(2)6-10(8-19)13(15)14-11-4-3-5-12(7-11)20(16,17)18/h3-5,7,9-10,19H,6,8H2,1-2H3,(H,14,15)(H,16,17,18)/p-1
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Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against enkephalinase enzyme from rat.


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
HTR4


(GUINEA PIG)
BDBM50112041
PNG
(4-Amino-N-{1-[1-(2-amino-3-methyl-butyryl)-piperid...)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CC2)C(=O)C(N)C(C)C)CC1
Show InChI InChI=1S/C24H38ClN5O3/c1-15(2)22(27)24(32)30-10-4-16(5-11-30)14-29-8-6-17(7-9-29)28-23(31)18-12-19(25)20(26)13-21(18)33-3/h12-13,15-17,22H,4-11,14,26-27H2,1-3H3,(H,28,31)
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n/an/a 2.5n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 4 receptor of guinea pig striatum using [3H]-GR-113,808 as radioligand


Bioorg Med Chem Lett 12: 967-70 (2002)


Article DOI: 10.1016/s0960-894x(02)00060-4
BindingDB Entry DOI: 10.7270/Q2RF5TB7
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50241107
PNG
(1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazo...)
Show SMILES Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)
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n/an/a 2.5n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligand


Bioorg Med Chem Lett 8: 619-24 (1999)


Article DOI: 10.1016/s0960-894x(98)00078-x
BindingDB Entry DOI: 10.7270/Q25Q4WN6
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50008599
PNG
(CHEMBL155953 | Sodium; 3-(2-mercaptomethyl-3-p-tol...)
Show SMILES Cc1ccc(CC(CS)C(=O)Nc2cccc(c2)S([O-])(=O)=O)cc1
Show InChI InChI=1S/C17H19NO4S2/c1-12-5-7-13(8-6-12)9-14(11-23)17(19)18-15-3-2-4-16(10-15)24(20,21)22/h2-8,10,14,23H,9,11H2,1H3,(H,18,19)(H,20,21,22)/p-1
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Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against enkephalinase enzyme from rat.


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
HTR4


(GUINEA PIG)
BDBM50112039
PNG
(4-Amino-N-{1-[1-(2-amino-pentanoyl)-piperidin-4-yl...)
Show SMILES CCCC(N)C(=O)N1CCC(CN2CCC(CC2)NC(=O)c2cc(Cl)c(N)cc2OC)CC1
Show InChI InChI=1S/C24H38ClN5O3/c1-3-4-20(26)24(32)30-11-5-16(6-12-30)15-29-9-7-17(8-10-29)28-23(31)18-13-19(25)21(27)14-22(18)33-2/h13-14,16-17,20H,3-12,15,26-27H2,1-2H3,(H,28,31)
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n/an/a 2.60n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 4 receptor of guinea pig striatum using [3H]-GR-113,808 as radioligand


Bioorg Med Chem Lett 12: 967-70 (2002)


Article DOI: 10.1016/s0960-894x(02)00060-4
BindingDB Entry DOI: 10.7270/Q2RF5TB7
More data for this
Ligand-Target Pair
HTR4


(GUINEA PIG)
BDBM50112038
PNG
(4-Amino-N-{1-[1-(2-amino-2-methyl-propionyl)-piper...)
Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CC2)C(=O)C(C)(C)N)CC1
Show InChI InChI=1S/C23H36ClN5O3/c1-23(2,26)22(31)29-10-4-15(5-11-29)14-28-8-6-16(7-9-28)27-21(30)17-12-18(24)19(25)13-20(17)32-3/h12-13,15-16H,4-11,14,25-26H2,1-3H3,(H,27,30)
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n/an/a 2.60n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-hydroxytryptamine 4 receptor of guinea pig striatum using [3H]-GR-113,808 as radioligand


Bioorg Med Chem Lett 12: 967-70 (2002)


Article DOI: 10.1016/s0960-894x(02)00060-4
BindingDB Entry DOI: 10.7270/Q2RF5TB7
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM21641
PNG
(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Show SMILES OC(=O)CNC(=O)C(CS)Cc1ccccc1
Show InChI InChI=1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15)
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n/an/a 2.60n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
The compound was tested in vitro for its inhibitory activity against Enkephalinase enzyme


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50070570
PNG
(5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-y...)
Show SMILES CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Cl)c(NC)cc1OC
Show InChI InChI=1S/C17H27ClN4O2/c1-5-22-7-6-21(3)10-12(11-22)20-17(23)13-8-14(18)15(19-2)9-16(13)24-4/h8-9,12,19H,5-7,10-11H2,1-4H3,(H,20,23)/t12-/m1/s1
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n/an/a 2.90n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor


Bioorg Med Chem Lett 8: 1551-4 (1999)


Article DOI: 10.1016/s0960-894x(98)00258-3
BindingDB Entry DOI: 10.7270/Q2CF9P7B
More data for this
Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50070570
PNG
(5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-y...)
Show SMILES CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Cl)c(NC)cc1OC
Show InChI InChI=1S/C17H27ClN4O2/c1-5-22-7-6-21(3)10-12(11-22)20-17(23)13-8-14(18)15(19-2)9-16(13)24-4/h8-9,12,19H,5-7,10-11H2,1-4H3,(H,20,23)/t12-/m1/s1
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n/an/a 2.90n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligand


Bioorg Med Chem Lett 8: 619-24 (1999)


Article DOI: 10.1016/s0960-894x(98)00078-x
BindingDB Entry DOI: 10.7270/Q25Q4WN6
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50008618
PNG
(CHEMBL155417 | Sodium; 2-(2-mercaptomethyl-3-p-tol...)
Show SMILES Cc1ccc(CC(CS)C(=O)NCCS([O-])(=O)=O)cc1
Show InChI InChI=1S/C13H19NO4S2/c1-10-2-4-11(5-3-10)8-12(9-19)13(15)14-6-7-20(16,17)18/h2-5,12,19H,6-9H2,1H3,(H,14,15)(H,16,17,18)/p-1
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n/an/a 3.10n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against enkephalinase enzyme from rat.


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50008589
PNG
(CHEMBL155783 | Sodium; 4-[2-mercaptomethyl-3-(4-me...)
Show SMILES COc1ccc(CC(CS)C(=O)Nc2ccc(cc2)S([O-])(=O)=O)cc1
Show InChI InChI=1S/C17H19NO5S2/c1-23-15-6-2-12(3-7-15)10-13(11-24)17(19)18-14-4-8-16(9-5-14)25(20,21)22/h2-9,13,24H,10-11H2,1H3,(H,18,19)(H,20,21,22)/p-1
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n/an/a 3.20n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against enkephalinase enzyme from rat.


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50109771
PNG
(3-{4-[(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-...)
Show SMILES CC(C)[C@H](NC(=O)COc1ccc(SCC(C)(C)C(O)=O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)c1nc2ccccc2o1
Show InChI InChI=1S/C35H44N4O8S/c1-20(2)28(30(41)32-36-24-10-7-8-12-26(24)47-32)38-31(42)25-11-9-17-39(25)33(43)29(21(3)4)37-27(40)18-46-22-13-15-23(16-14-22)48-19-35(5,6)34(44)45/h7-8,10,12-16,20-21,25,28-29H,9,11,17-19H2,1-6H3,(H,37,40)(H,38,42)(H,44,45)/t25-,28-,29-/m0/s1
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n/an/a 3.5n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCA


Bioorg Med Chem Lett 12: 551-5 (2002)


Article DOI: 10.1016/s0960-894x(01)00797-1
BindingDB Entry DOI: 10.7270/Q2TM79D1
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50008623
PNG
(CHEMBL440183 | Sodium; 2-[3-(4-fluoro-phenyl)-2-me...)
Show SMILES [O-]S(=O)(=O)CCNC(=O)C(CS)Cc1ccc(F)cc1
Show InChI InChI=1S/C12H16FNO4S2/c13-11-3-1-9(2-4-11)7-10(8-19)12(15)14-5-6-20(16,17)18/h1-4,10,19H,5-8H2,(H,14,15)(H,16,17,18)/p-1
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n/an/a 3.5n/an/an/an/an/an/a



Dainippon Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against enkephalinase enzyme from rat.


J Med Chem 35: 602-8 (1992)


Article DOI: 10.1021/jm00081a024
BindingDB Entry DOI: 10.7270/Q2QZ28ZD
More data for this
Ligand-Target Pair
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