BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 80 hits from Darmstadt   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM85093
PNG
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1
Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071215
PNG
(2-[4-(4'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-y...)
Show SMILES Fc1ccc(cc1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-7-5-18(6-8-20)19-4-1-3-17(15-19)16-25-11-13-26(14-12-25)21-23-9-2-10-24-21/h1-10,15H,11-14,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071216
PNG
(2-[4-(3-Thiophen-3-yl-benzyl)-piperazin-1-yl]-pyri...)
Show SMILES C(N1CCN(CC1)c1ncccn1)c1cccc(c1)-c1ccsc1
Show InChI InChI=1S/C19H20N4S/c1-3-16(13-17(4-1)18-5-12-24-15-18)14-22-8-10-23(11-9-22)19-20-6-2-7-21-19/h1-7,12-13,15H,8-11,14H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071211
PNG
(1-(2-Fluoro-phenyl)-4-[5-(4-fluoro-phenyl)-pyridin...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccccc2F)c1
Show InChI InChI=1S/C22H21F2N3/c23-20-7-5-18(6-8-20)19-13-17(14-25-15-19)16-26-9-11-27(12-10-26)22-4-2-1-3-21(22)24/h1-8,13-15H,9-12,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071217
PNG
(2-[4-(3'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-y...)
Show SMILES Fc1cccc(c1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-7-2-6-19(15-20)18-5-1-4-17(14-18)16-25-10-12-26(13-11-25)21-23-8-3-9-24-21/h1-9,14-15H,10-13,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071208
PNG
((1-Benzyl-piperidin-4-yl)-(3-isopropoxy-pyridin-2-...)
Show SMILES CC(C)Oc1cccnc1N(C)C1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H29N3O/c1-17(2)25-20-10-7-13-22-21(20)23(3)19-11-14-24(15-12-19)16-18-8-5-4-6-9-18/h4-10,13,17,19H,11-12,14-16H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM85093
PNG
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1
Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071214
PNG
(1-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-4-pheny...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C22H22FN3/c23-21-8-6-19(7-9-21)20-14-18(15-24-16-20)17-25-10-12-26(13-11-25)22-4-2-1-3-5-22/h1-9,14-16H,10-13,17H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071216
PNG
(2-[4-(3-Thiophen-3-yl-benzyl)-piperazin-1-yl]-pyri...)
Show SMILES C(N1CCN(CC1)c1ncccn1)c1cccc(c1)-c1ccsc1
Show InChI InChI=1S/C19H20N4S/c1-3-16(13-17(4-1)18-5-12-24-15-18)14-22-8-10-23(11-9-22)19-20-6-2-7-21-19/h1-7,12-13,15H,8-11,14H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071215
PNG
(2-[4-(4'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-y...)
Show SMILES Fc1ccc(cc1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-7-5-18(6-8-20)19-4-1-3-17(15-19)16-25-11-13-26(14-12-25)21-23-9-2-10-24-21/h1-10,15H,11-14,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071211
PNG
(1-(2-Fluoro-phenyl)-4-[5-(4-fluoro-phenyl)-pyridin...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccccc2F)c1
Show InChI InChI=1S/C22H21F2N3/c23-20-7-5-18(6-8-20)19-13-17(14-25-15-19)16-26-9-11-27(12-10-26)22-4-2-1-3-21(22)24/h1-8,13-15H,9-12,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071219
PNG
(1-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-4-pyrid...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-6-4-18(5-7-20)19-13-17(14-23-15-19)16-25-9-11-26(12-10-25)21-3-1-2-8-24-21/h1-8,13-15H,9-12,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071213
PNG
(2-{4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-pipe...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C20H20FN5/c21-19-4-2-17(3-5-19)18-12-16(13-22-14-18)15-25-8-10-26(11-9-25)20-23-6-1-7-24-20/h1-7,12-14H,8-11,15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071211
PNG
(1-(2-Fluoro-phenyl)-4-[5-(4-fluoro-phenyl)-pyridin...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccccc2F)c1
Show InChI InChI=1S/C22H21F2N3/c23-20-7-5-18(6-8-20)19-13-17(14-25-15-19)16-26-9-11-27(12-10-26)22-4-2-1-3-21(22)24/h1-8,13-15H,9-12,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071206
PNG
(2-[4-(2'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-y...)
Show SMILES Fc1ccccc1-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-8-2-1-7-19(20)18-6-3-5-17(15-18)16-25-11-13-26(14-12-25)21-23-9-4-10-24-21/h1-10,15H,11-14,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071208
PNG
((1-Benzyl-piperidin-4-yl)-(3-isopropoxy-pyridin-2-...)
Show SMILES CC(C)Oc1cccnc1N(C)C1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H29N3O/c1-17(2)25-20-10-7-13-22-21(20)23(3)19-11-14-24(15-12-19)16-18-8-5-4-6-9-18/h4-10,13,17,19H,11-12,14-16H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071218
PNG
(1-(4-Fluoro-phenyl)-4-[5-(4-fluoro-phenyl)-pyridin...)
Show SMILES Fc1ccc(cc1)N1CCN(Cc2cncc(c2)-c2ccc(F)cc2)CC1
Show InChI InChI=1S/C22H21F2N3/c23-20-3-1-18(2-4-20)19-13-17(14-25-15-19)16-26-9-11-27(12-10-26)22-7-5-21(24)6-8-22/h1-8,13-15H,9-12,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071213
PNG
(2-{4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-pipe...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C20H20FN5/c21-19-4-2-17(3-5-19)18-12-16(13-22-14-18)15-25-8-10-26(11-9-25)20-23-6-1-7-24-20/h1-7,12-14H,8-11,15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071217
PNG
(2-[4-(3'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-y...)
Show SMILES Fc1cccc(c1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-7-2-6-19(15-20)18-5-1-4-17(14-18)16-25-10-12-26(13-11-25)21-23-8-3-9-24-21/h1-9,14-15H,10-13,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 9n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50071219
PNG
(1-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-4-pyrid...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-6-4-18(5-7-20)19-13-17(14-23-15-19)16-25-9-11-26(12-10-25)21-3-1-2-8-24-21/h1-8,13-15H,9-12,16H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071205
PNG
(2-[4-(2'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Show SMILES COc1ccccc1-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C22H24N4O/c1-27-21-9-3-2-8-20(21)19-7-4-6-18(16-19)17-25-12-14-26(15-13-25)22-23-10-5-11-24-22/h2-11,16H,12-15,17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071220
PNG
(2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Show SMILES COc1cccc(c1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C22H24N4O/c1-27-21-8-3-7-20(16-21)19-6-2-5-18(15-19)17-25-11-13-26(14-12-25)22-23-9-4-10-24-22/h2-10,15-16H,11-14,17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 17n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071222
PNG
(2-[4-(9H-Fluoren-1-ylmethyl)-piperazin-1-yl]-pyrim...)
Show SMILES C(N1CCN(CC1)c1ncccn1)c1cccc-2c1Cc1ccccc-21
Show InChI InChI=1S/C22H22N4/c1-2-7-19-17(5-1)15-21-18(6-3-8-20(19)21)16-25-11-13-26(14-12-25)22-23-9-4-10-24-22/h1-10H,11-16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50071211
PNG
(1-(2-Fluoro-phenyl)-4-[5-(4-fluoro-phenyl)-pyridin...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccccc2F)c1
Show InChI InChI=1S/C22H21F2N3/c23-20-7-5-18(6-8-20)19-13-17(14-25-15-19)16-26-9-11-27(12-10-26)22-4-2-1-3-21(22)24/h1-8,13-15H,9-12,16H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50071214
PNG
(1-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-4-pheny...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C22H22FN3/c23-21-8-6-19(7-9-21)20-14-18(15-24-16-20)17-25-10-12-26(13-11-25)22-4-2-1-3-5-22/h1-9,14-16H,10-13,17H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 23n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071204
PNG
(4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-3,4,5,6...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2cnccn2)c1
Show InChI InChI=1S/C20H20FN5/c21-19-3-1-17(2-4-19)18-11-16(12-23-13-18)15-25-7-9-26(10-8-25)20-14-22-5-6-24-20/h1-6,11-14H,7-10,15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50071211
PNG
(1-(2-Fluoro-phenyl)-4-[5-(4-fluoro-phenyl)-pyridin...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccccc2F)c1
Show InChI InChI=1S/C22H21F2N3/c23-20-7-5-18(6-8-20)19-13-17(14-25-15-19)16-26-9-11-27(12-10-26)22-4-2-1-3-21(22)24/h1-8,13-15H,9-12,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071214
PNG
(1-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-4-pheny...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C22H22FN3/c23-21-8-6-19(7-9-21)20-14-18(15-24-16-20)17-25-10-12-26(13-11-25)22-4-2-1-3-5-22/h1-9,14-16H,10-13,17H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 33n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50071215
PNG
(2-[4-(4'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-y...)
Show SMILES Fc1ccc(cc1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-7-5-18(6-8-20)19-4-1-3-17(15-19)16-25-11-13-26(14-12-25)21-23-9-2-10-24-21/h1-10,15H,11-14,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 49n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50071212
PNG
(2-[4-(4'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Show SMILES COc1ccc(cc1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C22H24N4O/c1-27-21-8-6-19(7-9-21)20-5-2-4-18(16-20)17-25-12-14-26(15-13-25)22-23-10-3-11-24-22/h2-11,16H,12-15,17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptors; D2 & D4


(Homo sapiens (Human))
BDBM50071212
PNG
(2-[4-(4'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Show SMILES COc1ccc(cc1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C22H24N4O/c1-27-21-8-6-19(7-9-21)20-5-2-4-18(16-20)17-25-12-14-26(15-13-25)22-23-10-3-11-24-22/h2-11,16H,12-15,17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 57n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D4 expressed in CHO cells using [3H]spiperone


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071215
PNG
(2-[4-(4'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-y...)
Show SMILES Fc1ccc(cc1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-7-5-18(6-8-20)19-4-1-3-17(15-19)16-25-11-13-26(14-12-25)21-23-9-2-10-24-21/h1-10,15H,11-14,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 59n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50071219
PNG
(1-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-4-pyrid...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-6-4-18(5-7-20)19-13-17(14-23-15-19)16-25-9-11-26(12-10-25)21-3-1-2-8-24-21/h1-8,13-15H,9-12,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50071214
PNG
(1-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-4-pheny...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C22H22FN3/c23-21-8-6-19(7-9-21)20-14-18(15-24-16-20)17-25-10-12-26(13-11-25)22-4-2-1-3-5-22/h1-9,14-16H,10-13,17H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50071218
PNG
(1-(4-Fluoro-phenyl)-4-[5-(4-fluoro-phenyl)-pyridin...)
Show SMILES Fc1ccc(cc1)N1CCN(Cc2cncc(c2)-c2ccc(F)cc2)CC1
Show InChI InChI=1S/C22H21F2N3/c23-20-3-1-18(2-4-20)19-13-17(14-25-15-19)16-26-9-11-27(12-10-26)22-7-5-21(24)6-8-22/h1-8,13-15H,9-12,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071212
PNG
(2-[4-(4'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-...)
Show SMILES COc1ccc(cc1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C22H24N4O/c1-27-21-8-6-19(7-9-21)20-5-2-4-18(16-20)17-25-12-14-26(15-13-25)22-23-10-3-11-24-22/h2-11,16H,12-15,17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 72n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM85093
PNG
(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Show SMILES Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1
Show InChI InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 80n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50071217
PNG
(2-[4-(3'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-y...)
Show SMILES Fc1cccc(c1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-7-2-6-19(15-20)18-5-1-4-17(14-18)16-25-10-12-26(13-11-25)21-23-8-3-9-24-21/h1-9,14-15H,10-13,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 81n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50071210
PNG
(2-[4-(9H-Fluoren-4-ylmethyl)-piperazin-1-yl]-pyrim...)
Show SMILES C(N1CCN(CC1)c1ncccn1)c1cccc2Cc3ccccc3-c12
Show InChI InChI=1S/C22H22N4/c1-2-8-20-17(5-1)15-18-6-3-7-19(21(18)20)16-25-11-13-26(14-12-25)22-23-9-4-10-24-22/h1-10H,11-16H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50071224
PNG
(2-[4-(9H-Fluoren-2-ylmethyl)-piperazin-1-yl]-pyrim...)
Show SMILES C(N1CCN(CC1)c1ncccn1)c1ccc-2c(Cc3ccccc-23)c1
Show InChI InChI=1S/C22H22N4/c1-2-5-20-18(4-1)15-19-14-17(6-7-21(19)20)16-25-10-12-26(13-11-25)22-23-8-3-9-24-22/h1-9,14H,10-13,15-16H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50071213
PNG
(2-{4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-pipe...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C20H20FN5/c21-19-4-2-17(3-5-19)18-12-16(13-22-14-18)15-25-8-10-26(11-9-25)20-23-6-1-7-24-20/h1-7,12-14H,8-11,15H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50071207
PNG
(2-(4-Dibenzofuran-4-ylmethyl-piperazin-1-yl)-pyrim...)
Show SMILES C(N1CCN(CC1)c1ncccn1)c1cccc2c3ccccc3oc12
Show InChI InChI=1S/C21H20N4O/c1-2-8-19-17(6-1)18-7-3-5-16(20(18)26-19)15-24-11-13-25(14-12-24)21-22-9-4-10-23-21/h1-10H,11-15H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50071221
PNG
(2-(4-Dibenzothiophen-4-ylmethyl-piperazin-1-yl)-py...)
Show SMILES C(N1CCN(CC1)c1ncccn1)c1cccc2c3ccccc3sc12
Show InChI InChI=1S/C21H20N4S/c1-2-8-19-17(6-1)18-7-3-5-16(20(18)26-19)15-24-11-13-25(14-12-24)21-22-9-4-10-23-21/h1-10H,11-15H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50071223
PNG
(2-[4-(9H-Fluoren-9-ylmethyl)-piperazin-1-yl]-pyrim...)
Show SMILES C(C1c2ccccc2-c2ccccc12)N1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C22H22N4/c1-3-8-19-17(6-1)18-7-2-4-9-20(18)21(19)16-25-12-14-26(15-13-25)22-23-10-5-11-24-22/h1-11,21H,12-16H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to 5-HT1A receptor in rat hippocampus by [3H]8-OH-DPAT displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50071213
PNG
(2-{4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-pipe...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C20H20FN5/c21-19-4-2-17(3-5-19)18-12-16(13-22-14-18)15-25-8-10-26(11-9-25)20-23-6-1-7-24-20/h1-7,12-14H,8-11,15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071213
PNG
(2-{4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-pipe...)
Show SMILES Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C20H20FN5/c21-19-4-2-17(3-5-19)18-12-16(13-22-14-18)15-25-8-10-26(11-9-25)20-23-6-1-7-24-20/h1-7,12-14H,8-11,15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071216
PNG
(2-[4-(3-Thiophen-3-yl-benzyl)-piperazin-1-yl]-pyri...)
Show SMILES C(N1CCN(CC1)c1ncccn1)c1cccc(c1)-c1ccsc1
Show InChI InChI=1S/C19H20N4S/c1-3-16(13-17(4-1)18-5-12-24-15-18)14-22-8-10-23(11-9-22)19-20-6-2-7-21-19/h1-7,12-13,15H,8-11,14H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071217
PNG
(2-[4-(3'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-y...)
Show SMILES Fc1cccc(c1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-7-2-6-19(15-20)18-5-1-4-17(14-18)16-25-10-12-26(13-11-25)21-23-8-3-9-24-21/h1-9,14-15H,10-13,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50071218
PNG
(1-(4-Fluoro-phenyl)-4-[5-(4-fluoro-phenyl)-pyridin...)
Show SMILES Fc1ccc(cc1)N1CCN(Cc2cncc(c2)-c2ccc(F)cc2)CC1
Show InChI InChI=1S/C22H21F2N3/c23-20-3-1-18(2-4-20)19-13-17(14-25-15-19)16-26-9-11-27(12-10-26)22-7-5-21(24)6-8-22/h1-8,13-15H,9-12,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D3 expressed in CHO cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50071206
PNG
(2-[4-(2'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-y...)
Show SMILES Fc1ccccc1-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Show InChI InChI=1S/C21H21FN4/c22-20-8-2-1-7-19(20)18-6-3-5-17(15-18)16-25-11-13-26(14-12-25)21-23-9-4-10-24-21/h1-10,15H,11-14,16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Darmstadt

Curated by ChEMBL


Assay Description
Binding affinity to cloned human Dopamine receptor D2 expressed in A9L cells by [3H]spiperone displacement.


Bioorg Med Chem Lett 8: 2033-8 (1999)


Article DOI: 10.1016/s0960-894x(98)00361-8
BindingDB Entry DOI: 10.7270/Q2222V8M
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 80 total )  |  Next  |  Last  >>
Jump to: