BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 10 hits from Delhi Institute of Pharmaceutical Sciences and Research   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM106752
PNG
(2‐[2‐(3‐fluoropyrrolidine‐...)
Show SMILES FC1CCN(C1)C(=O)C1CCCN1CC(=O)N1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C19H27FN6O2/c20-15-4-8-26(13-15)18(28)16-3-1-7-25(16)14-17(27)23-9-11-24(12-10-23)19-21-5-2-6-22-19/h2,5-6,15-16H,1,3-4,7-14H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 430n/an/an/an/an/an/a



Delhi Institute of Pharmaceutical Sciences and Research



Assay Description
The enzyme assay was performed using DPP IV drug discovery kit (BML-AK 499; Enzo Life Sciences, Plymouth Meeting, PA, USA). The activity of test com...


Chem Biol Drug Des 82: 156-66 (2013)


Article DOI: 10.1111/cbdd.12142
BindingDB Entry DOI: 10.7270/Q2ZC81H8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM106751
PNG
(2‐[2‐(3‐fluoropyrrolidine‐...)
Show SMILES FC1CCN(C1)C(=O)C1CCCN1CC(=O)N1CCN(CC1)c1ccccn1
Show InChI InChI=1S/C20H28FN5O2/c21-16-6-9-26(14-16)20(28)17-4-3-8-25(17)15-19(27)24-12-10-23(11-13-24)18-5-1-2-7-22-18/h1-2,5,7,16-17H,3-4,6,8-15H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 830n/an/an/an/an/an/a



Delhi Institute of Pharmaceutical Sciences and Research



Assay Description
The enzyme assay was performed using DPP IV drug discovery kit (BML-AK 499; Enzo Life Sciences, Plymouth Meeting, PA, USA). The activity of test com...


Chem Biol Drug Des 82: 156-66 (2013)


Article DOI: 10.1111/cbdd.12142
BindingDB Entry DOI: 10.7270/Q2ZC81H8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM106759
PNG
((2S)‐2‐amino‐3‐methyl̴...)
Show SMILES CCC(C)[C@H](N)C(=O)N1CCSC1
Show InChI InChI=1S/C9H18N2OS/c1-3-7(2)8(10)9(12)11-4-5-13-6-11/h7-8H,3-6,10H2,1-2H3/t7?,8-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



Delhi Institute of Pharmaceutical Sciences and Research



Assay Description
The enzyme assay was performed using DPP IV drug discovery kit (BML-AK 499; Enzo Life Sciences, Plymouth Meeting, PA, USA). The activity of test com...


Chem Biol Drug Des 82: 156-66 (2013)


Article DOI: 10.1111/cbdd.12142
BindingDB Entry DOI: 10.7270/Q2ZC81H8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM106753
PNG
(1‐(azepan‐1‐yl)‐2‐[2...)
Show SMILES FC1CCN(C1)C(=O)C1CCCN1CC(=O)N1CCCCCC1
Show InChI InChI=1S/C17H28FN3O2/c18-14-7-11-21(12-14)17(23)15-6-5-10-20(15)13-16(22)19-8-3-1-2-4-9-19/h14-15H,1-13H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.47E+3n/an/an/an/an/an/a



Delhi Institute of Pharmaceutical Sciences and Research



Assay Description
The enzyme assay was performed using DPP IV drug discovery kit (BML-AK 499; Enzo Life Sciences, Plymouth Meeting, PA, USA). The activity of test com...


Chem Biol Drug Des 82: 156-66 (2013)


Article DOI: 10.1111/cbdd.12142
BindingDB Entry DOI: 10.7270/Q2ZC81H8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM106750
PNG
((3-fluoropyrrolidin-1-yl) (pyrrolidin-2-yl)methano...)
Show SMILES FC1CCN(C1)C(=O)C1CCCN1
Show InChI InChI=1S/C9H15FN2O/c10-7-3-5-12(6-7)9(13)8-2-1-4-11-8/h7-8,11H,1-6H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.27E+3n/an/an/an/an/an/a



Delhi Institute of Pharmaceutical Sciences and Research



Assay Description
The enzyme assay was performed using DPP IV drug discovery kit (BML-AK 499; Enzo Life Sciences, Plymouth Meeting, PA, USA). The activity of test com...


Chem Biol Drug Des 82: 156-66 (2013)


Article DOI: 10.1111/cbdd.12142
BindingDB Entry DOI: 10.7270/Q2ZC81H8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM106756
PNG
((3-Fluoro-pyrrolidin-1-yl)-[1-(2-piperidin-1-yl-et...)
Show SMILES FC1CCN(C1)C(=O)C1CCCN1CCN1CCCCC1
Show InChI InChI=1S/C16H28FN3O/c17-14-6-10-20(13-14)16(21)15-5-4-9-19(15)12-11-18-7-2-1-3-8-18/h14-15H,1-13H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.49E+3n/an/an/an/an/an/a



Delhi Institute of Pharmaceutical Sciences and Research



Assay Description
The enzyme assay was performed using DPP IV drug discovery kit (BML-AK 499; Enzo Life Sciences, Plymouth Meeting, PA, USA). The activity of test com...


Chem Biol Drug Des 82: 156-66 (2013)


Article DOI: 10.1111/cbdd.12142
BindingDB Entry DOI: 10.7270/Q2ZC81H8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM106754
PNG
(2‐[2‐(3‐fluoropyrrolidine‐...)
Show SMILES FC1CCN(C1)C(=O)C1CCCN1CC(=O)N1CCCCC1
Show InChI InChI=1S/C16H26FN3O2/c17-13-6-10-20(11-13)16(22)14-5-4-9-19(14)12-15(21)18-7-2-1-3-8-18/h13-14H,1-12H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.88E+3n/an/an/an/an/an/a



Delhi Institute of Pharmaceutical Sciences and Research



Assay Description
The enzyme assay was performed using DPP IV drug discovery kit (BML-AK 499; Enzo Life Sciences, Plymouth Meeting, PA, USA). The activity of test com...


Chem Biol Drug Des 82: 156-66 (2013)


Article DOI: 10.1111/cbdd.12142
BindingDB Entry DOI: 10.7270/Q2ZC81H8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM106755
PNG
(2‐[2‐(3‐fluoropyrrolidine‐...)
Show SMILES FC1CCN(C1)C(=O)C1CCCN1CC(=O)N1CCCC1
Show InChI InChI=1S/C15H24FN3O2/c16-12-5-9-19(10-12)15(21)13-4-3-8-18(13)11-14(20)17-6-1-2-7-17/h12-13H,1-11H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.67E+4n/an/an/an/an/an/a



Delhi Institute of Pharmaceutical Sciences and Research



Assay Description
The enzyme assay was performed using DPP IV drug discovery kit (BML-AK 499; Enzo Life Sciences, Plymouth Meeting, PA, USA). The activity of test com...


Chem Biol Drug Des 82: 156-66 (2013)


Article DOI: 10.1111/cbdd.12142
BindingDB Entry DOI: 10.7270/Q2ZC81H8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM106757
PNG
([1-(2-Diethylamino-ethyl)-pyrrolidin-2-yl]-(3-fluo...)
Show SMILES CCN(CC)CCN1CCCC1C(=O)N1CCC(F)C1
Show InChI InChI=1S/C15H28FN3O/c1-3-17(4-2)10-11-18-8-5-6-14(18)15(20)19-9-7-13(16)12-19/h13-14H,3-12H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.38E+4n/an/an/an/an/an/a



Delhi Institute of Pharmaceutical Sciences and Research



Assay Description
The enzyme assay was performed using DPP IV drug discovery kit (BML-AK 499; Enzo Life Sciences, Plymouth Meeting, PA, USA). The activity of test com...


Chem Biol Drug Des 82: 156-66 (2013)


Article DOI: 10.1111/cbdd.12142
BindingDB Entry DOI: 10.7270/Q2ZC81H8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4 (DPP4)


(Homo sapiens (human))
BDBM106758
PNG
({1-[2-(dimethylamino)ethyl]pyrrolidin-2-yl}(3- flu...)
Show SMILES CN(C)CCN1CCCC1C(=O)N1CCC(F)C1
Show InChI InChI=1S/C13H24FN3O/c1-15(2)8-9-16-6-3-4-12(16)13(18)17-7-5-11(14)10-17/h11-12H,3-10H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.02E+4n/an/an/an/an/an/a



Delhi Institute of Pharmaceutical Sciences and Research



Assay Description
The enzyme assay was performed using DPP IV drug discovery kit (BML-AK 499; Enzo Life Sciences, Plymouth Meeting, PA, USA). The activity of test com...


Chem Biol Drug Des 82: 156-66 (2013)


Article DOI: 10.1111/cbdd.12142
BindingDB Entry DOI: 10.7270/Q2ZC81H8
More data for this
Ligand-Target Pair