BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 36 hits from Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218963
PNG
(CHEMBL297626)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(Cl)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H17ClO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.0100n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218974
PNG
(CHEMBL296206)
Show SMILES CCCc1ccc(cc1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C22H24O4S/c1-5-6-15-7-9-16(10-8-15)19-20(26-22(2,3)21(19)23)17-11-13-18(14-12-17)27(4,24)25/h7-14H,5-6H2,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.0200n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218973
PNG
(CHEMBL44001)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H17FO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.0200n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM11639
PNG
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 0.0200n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218966
PNG
(CHEMBL44878)
Show SMILES CC1(C)OC(=C(C1=O)c1cc(F)ccc1F)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H16F2O4S/c1-19(2)18(22)16(14-10-12(20)6-9-15(14)21)17(25-19)11-4-7-13(8-5-11)26(3,23)24/h4-10H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.0300n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218970
PNG
(CHEMBL43893)
Show SMILES CC1(C)OC(=C(C1=O)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H16Cl2O4S/c1-19(2)18(22)16(12-8-13(20)10-14(21)9-12)17(25-19)11-4-6-15(7-5-11)26(3,23)24/h4-10H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.0300n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218967
PNG
(CHEMBL297750)
Show SMILES CC(C)c1ccc(cc1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C22H24O4S/c1-14(2)15-6-8-16(9-7-15)19-20(26-22(3,4)21(19)23)17-10-12-18(13-11-17)27(5,24)25/h6-14H,1-5H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.0300n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218959
PNG
(CHEMBL296082)
Show SMILES CC(C)c1cccc(c1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C22H24O4S/c1-14(2)16-7-6-8-17(13-16)19-20(26-22(3,4)21(19)23)15-9-11-18(12-10-15)27(5,24)25/h6-14H,1-5H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 0.0300n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218964
PNG
(CHEMBL44223)
Show SMILES CC1(C)OC(=C(C1=O)c1cc(F)cc(F)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H16F2O4S/c1-19(2)18(22)16(12-8-13(20)10-14(21)9-12)17(25-19)11-4-6-15(7-5-11)26(3,23)24/h4-10H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.0300n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218968
PNG
(CHEMBL416101)
Show SMILES CC1(C)OC(=C(C1=O)c1ccc(F)c(F)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H16F2O4S/c1-19(2)18(22)16(12-6-9-14(20)15(21)10-12)17(25-19)11-4-7-13(8-5-11)26(3,23)24/h4-10H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.0500n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218962
PNG
(CHEMBL47022)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C20H17F3O4S/c1-19(2)18(24)16(13-5-4-6-14(11-13)20(21,22)23)17(27-19)12-7-9-15(10-8-12)28(3,25)26/h4-11H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.0500n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218965
PNG
(CHEMBL45396)
Show SMILES CC(=O)c1cccc(c1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C21H20O5S/c1-13(22)15-6-5-7-16(12-15)18-19(26-21(2,3)20(18)23)14-8-10-17(11-9-14)27(4,24)25/h5-12H,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.0500n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218972
PNG
(CHEMBL298468)
Show SMILES CC1(C)OC(=C(C1=O)c1ccccc1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H18O4S/c1-19(2)18(20)16(13-7-5-4-6-8-13)17(23-19)14-9-11-15(12-10-14)24(3,21)22/h4-12H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.0500n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM22369
PNG
(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1
Show InChI InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 0.0600n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218961
PNG
(CHEMBL298024)
Show SMILES COc1ccccc1C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C20H20O5S/c1-20(2)19(21)17(15-7-5-6-8-16(15)24-3)18(25-20)13-9-11-14(12-10-13)26(4,22)23/h5-12H,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.100n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218960
PNG
(CHEMBL47941)
Show SMILES CC1(C)OC(=C(C1=O)c1ccccc1Cl)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H17ClO4S/c1-19(2)18(21)16(14-6-4-5-7-15(14)20)17(24-19)12-8-10-13(11-9-12)25(3,22)23/h4-11H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.300n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218969
PNG
(CHEMBL296701)
Show SMILES CC(O)c1ccc(cc1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C21H22O5S/c1-13(22)14-5-7-15(8-6-14)18-19(26-21(2,3)20(18)23)16-9-11-17(12-10-16)27(4,24)25/h5-13,22H,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 0.300n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50218971
PNG
(CHEMBL295990)
Show SMILES Cc1ccccc1C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C20H20O4S/c1-13-7-5-6-8-16(13)17-18(24-20(2,3)19(17)21)14-9-11-15(12-10-14)25(4,22)23/h5-12H,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.300n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM11639
PNG
(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F
Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 1.90n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218963
PNG
(CHEMBL297626)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(Cl)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H17ClO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218962
PNG
(CHEMBL47022)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C20H17F3O4S/c1-19(2)18(24)16(13-5-4-6-14(11-13)20(21,22)23)17(27-19)12-7-9-15(10-8-12)28(3,25)26/h4-11H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218970
PNG
(CHEMBL43893)
Show SMILES CC1(C)OC(=C(C1=O)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H16Cl2O4S/c1-19(2)18(22)16(12-8-13(20)10-14(21)9-12)17(25-19)11-4-6-15(7-5-11)26(3,23)24/h4-10H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218972
PNG
(CHEMBL298468)
Show SMILES CC1(C)OC(=C(C1=O)c1ccccc1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H18O4S/c1-19(2)18(20)16(13-7-5-4-6-8-13)17(23-19)14-9-11-15(12-10-14)24(3,21)22/h4-12H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218967
PNG
(CHEMBL297750)
Show SMILES CC(C)c1ccc(cc1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C22H24O4S/c1-14(2)15-6-8-16(9-7-15)19-20(26-22(3,4)21(19)23)17-10-12-18(13-11-17)27(5,24)25/h6-14H,1-5H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218974
PNG
(CHEMBL296206)
Show SMILES CCCc1ccc(cc1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C22H24O4S/c1-5-6-15-7-9-16(10-8-15)19-20(26-22(2,3)21(19)23)17-11-13-18(14-12-17)27(4,24)25/h7-14H,5-6H2,1-4H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218968
PNG
(CHEMBL416101)
Show SMILES CC1(C)OC(=C(C1=O)c1ccc(F)c(F)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H16F2O4S/c1-19(2)18(22)16(12-6-9-14(20)15(21)10-12)17(25-19)11-4-7-13(8-5-11)26(3,23)24/h4-10H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218973
PNG
(CHEMBL44001)
Show SMILES CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H17FO4S/c1-19(2)18(21)16(13-5-4-6-14(20)11-13)17(24-19)12-7-9-15(10-8-12)25(3,22)23/h4-11H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218964
PNG
(CHEMBL44223)
Show SMILES CC1(C)OC(=C(C1=O)c1cc(F)cc(F)c1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H16F2O4S/c1-19(2)18(22)16(12-8-13(20)10-14(21)9-12)17(25-19)11-4-6-15(7-5-11)26(3,23)24/h4-10H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218971
PNG
(CHEMBL295990)
Show SMILES Cc1ccccc1C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C20H20O4S/c1-13-7-5-6-8-16(13)17-18(24-20(2,3)19(17)21)14-9-11-15(12-10-14)25(4,22)23/h5-12H,1-4H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218966
PNG
(CHEMBL44878)
Show SMILES CC1(C)OC(=C(C1=O)c1cc(F)ccc1F)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H16F2O4S/c1-19(2)18(22)16(14-10-12(20)6-9-15(14)21)17(25-19)11-4-7-13(8-5-11)26(3,23)24/h4-10H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218959
PNG
(CHEMBL296082)
Show SMILES CC(C)c1cccc(c1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C22H24O4S/c1-14(2)16-7-6-8-17(13-16)19-20(26-22(3,4)21(19)23)15-9-11-18(12-10-15)27(5,24)25/h6-14H,1-5H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218961
PNG
(CHEMBL298024)
Show SMILES COc1ccccc1C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C20H20O5S/c1-20(2)19(21)17(15-7-5-6-8-16(15)24-3)18(25-20)13-9-11-14(12-10-13)26(4,22)23/h5-12H,1-4H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218960
PNG
(CHEMBL47941)
Show SMILES CC1(C)OC(=C(C1=O)c1ccccc1Cl)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C19H17ClO4S/c1-19(2)18(21)16(14-6-4-5-7-15(14)20)17(24-19)12-8-10-13(11-9-12)25(3,22)23/h4-11H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218965
PNG
(CHEMBL45396)
Show SMILES CC(=O)c1cccc(c1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C21H20O5S/c1-13(22)15-6-5-7-16(12-15)18-19(26-21(2,3)20(18)23)14-8-10-17(11-9-14)27(4,24)25/h5-12H,1-4H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM50218969
PNG
(CHEMBL296701)
Show SMILES CC(O)c1ccc(cc1)C1=C(OC(C)(C)C1=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C21H22O5S/c1-13(22)14-5-7-15(8-6-14)18-19(26-21(2,3)20(18)23)16-9-11-17(12-10-16)27(4,24)25/h5-13,22H,1-4H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 50n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase)


(Mus musculus)
BDBM22369
PNG
(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)
Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1
Show InChI InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Drug Discovery, Pacific Corporation R&D Center, Yongin-si, Kyounggi-do, South Korea.

Curated by ChEMBL


Assay Description
Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophages


Bioorg Med Chem Lett 11: 165-8 (2001)


Article DOI: 10.1016/s0960-894x(00)00634-x
More data for this
Ligand-Target Pair