BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 61 hits from EGIS Pharmaceuticals Plc   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354515
PNG
(CHEMBL261719)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C24H30ClN3O/c1-2-24(21-7-3-4-8-22(21)26-23(24)29)13-5-6-14-27-15-17-28(18-16-27)20-11-9-19(25)10-12-20/h3-4,7-12H,2,5-6,13-18H2,1H3,(H,26,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.380n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354492
PNG
(CHEMBL260994)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCC2C(=O)Nc3ccccc23)CC1
Show InChI InChI=1S/C22H26ClN3O/c23-17-8-10-18(11-9-17)26-15-13-25(14-16-26)12-4-3-6-20-19-5-1-2-7-21(19)24-22(20)27/h1-2,5,7-11,20H,3-4,6,12-16H2,(H,24,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.380n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354521
PNG
(CHEMBL408976)
Show SMILES CCC1(CCCCN2CCN(CC2)c2cccc(Cl)c2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C24H30ClN3O/c1-2-24(21-10-3-4-11-22(21)26-23(24)29)12-5-6-13-27-14-16-28(17-15-27)20-9-7-8-19(25)18-20/h3-4,7-11,18H,2,5-6,12-17H2,1H3,(H,26,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.410n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354506
PNG
(CHEMBL260872)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(F)cc2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C24H30FN3O/c1-2-24(21-7-3-4-8-22(21)26-23(24)29)13-5-6-14-27-15-17-28(18-16-27)20-11-9-19(25)10-12-20/h3-4,7-12H,2,5-6,13-18H2,1H3,(H,26,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.430n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354522
PNG
(CHEMBL261209)
Show SMILES Clc1cccc(c1)N1CCN(CCCCC2C(=O)Nc3ccccc23)CC1
Show InChI InChI=1S/C22H26ClN3O/c23-17-6-5-7-18(16-17)26-14-12-25(13-15-26)11-4-3-9-20-19-8-1-2-10-21(19)24-22(20)27/h1-2,5-8,10,16,20H,3-4,9,11-15H2,(H,24,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.490n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376328
PNG
(CHEMBL406414)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(F)c(Cl)c2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C24H29ClFN3O/c1-2-24(19-7-3-4-8-22(19)27-23(24)30)11-5-6-12-28-13-15-29(16-14-28)18-9-10-21(26)20(25)17-18/h3-4,7-10,17H,2,5-6,11-16H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.600n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354503
PNG
(CHEMBL259087)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)c(Cl)c2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C24H29Cl2N3O/c1-2-24(19-7-3-4-8-22(19)27-23(24)30)11-5-6-12-28-13-15-29(16-14-28)18-9-10-20(25)21(26)17-18/h3-4,7-10,17H,2,5-6,11-16H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.630n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376339
PNG
(CHEMBL259086)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(C)c(Cl)c2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C25H32ClN3O/c1-3-25(21-8-4-5-9-23(21)27-24(25)30)12-6-7-13-28-14-16-29(17-15-28)20-11-10-19(2)22(26)18-20/h4-5,8-11,18H,3,6-7,12-17H2,1-2H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.660n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376324
PNG
(CHEMBL259549)
Show SMILES CCC1(CCCCN2CCN(CC2)c2cccc(Cl)c2)C(=O)Nc2cc(F)ccc12
Show InChI InChI=1S/C24H29ClFN3O/c1-2-24(21-9-8-19(26)17-22(21)27-23(24)30)10-3-4-11-28-12-14-29(15-13-28)20-7-5-6-18(25)16-20/h5-9,16-17H,2-4,10-15H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.670n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354493
PNG
(CHEMBL409662)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2cc(F)ccc12
Show InChI InChI=1S/C24H29ClFN3O/c1-2-24(21-10-7-19(26)17-22(21)27-23(24)30)11-3-4-12-28-13-15-29(16-14-28)20-8-5-18(25)6-9-20/h5-10,17H,2-4,11-16H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.790n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376327
PNG
(CHEMBL410226)
Show SMILES CCC1(CCCCN2CCC(=CC2)c2ccc(Cl)cc2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C25H29ClN2O/c1-2-25(22-7-3-4-8-23(22)27-24(25)29)15-5-6-16-28-17-13-20(14-18-28)19-9-11-21(26)12-10-19/h3-4,7-13H,2,5-6,14-18H2,1H3,(H,27,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.02n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354497
PNG
(CHEMBL410225)
Show SMILES CCC1(CCCCN2CCC(=CC2)c2ccc(F)cc2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C25H29FN2O/c1-2-25(22-7-3-4-8-23(22)27-24(25)29)15-5-6-16-28-17-13-20(14-18-28)19-9-11-21(26)12-10-19/h3-4,7-13H,2,5-6,14-18H2,1H3,(H,27,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.19n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376336
PNG
(CHEMBL262068)
Show SMILES CCC1(CCCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C25H32ClN3O/c1-2-25(22-8-4-5-9-23(22)27-24(25)30)14-6-3-7-15-28-16-18-29(19-17-28)21-12-10-20(26)11-13-21/h4-5,8-13H,2-3,6-7,14-19H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.24n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376342
PNG
(CHEMBL258496)
Show SMILES CCC1(CCCCCN2CCN(CC2)c2cccc(Cl)c2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C25H32ClN3O/c1-2-25(22-11-4-5-12-23(22)27-24(25)30)13-6-3-7-14-28-15-17-29(18-16-28)21-10-8-9-20(26)19-21/h4-5,8-12,19H,2-3,6-7,13-18H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.45n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376332
PNG
(CHEMBL259216)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(F)cc2)C(=O)Nc2ccc(F)cc12
Show InChI InChI=1S/C24H29F2N3O/c1-2-24(21-17-19(26)7-10-22(21)27-23(24)30)11-3-4-12-28-13-15-29(16-14-28)20-8-5-18(25)6-9-20/h5-10,17H,2-4,11-16H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.5n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376340
PNG
(CHEMBL408191)
Show SMILES CC(C)CC1(CCCCN2CCN(CC2)c2cccc(Cl)c2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C26H34ClN3O/c1-20(2)19-26(23-10-3-4-11-24(23)28-25(26)31)12-5-6-13-29-14-16-30(17-15-29)22-9-7-8-21(27)18-22/h3-4,7-11,18,20H,5-6,12-17,19H2,1-2H3,(H,28,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.80n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376333
PNG
(CHEMBL408450)
Show SMILES Fc1ccc2NC(=O)C(CCCCN3CCN(CC3)c3cccc(Cl)c3)c2c1
Show InChI InChI=1S/C22H25ClFN3O/c23-16-4-3-5-18(14-16)27-12-10-26(11-13-27)9-2-1-6-19-20-15-17(24)7-8-21(20)25-22(19)28/h3-5,7-8,14-15,19H,1-2,6,9-13H2,(H,25,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.96n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376335
PNG
(CHEMBL410628)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccccc2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C24H31N3O/c1-2-24(21-12-6-7-13-22(21)25-23(24)28)14-8-9-15-26-16-18-27(19-17-26)20-10-4-3-5-11-20/h3-7,10-13H,2,8-9,14-19H2,1H3,(H,25,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.07n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354491
PNG
(CHEMBL259550)
Show SMILES CCC1(CCCCN2CCN(CC2)c2cccc(Cl)c2)C(=O)Nc2ccc(F)cc12
Show InChI InChI=1S/C24H29ClFN3O/c1-2-24(21-17-19(26)8-9-22(21)27-23(24)30)10-3-4-11-28-12-14-29(15-13-28)20-7-5-6-18(25)16-20/h5-9,16-17H,2-4,10-15H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.11n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376330
PNG
(CHEMBL260762)
Show SMILES CCC1(CCCCN2CCN(CC2)c2cccc(OC)c2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C25H33N3O2/c1-3-25(22-11-4-5-12-23(22)26-24(25)29)13-6-7-14-27-15-17-28(18-16-27)20-9-8-10-21(19-20)30-2/h4-5,8-12,19H,3,6-7,13-18H2,1-2H3,(H,26,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.55n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354514
PNG
(CHEMBL259010)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2ccc(F)cc12
Show InChI InChI=1S/C24H29ClFN3O/c1-2-24(21-17-19(26)7-10-22(21)27-23(24)30)11-3-4-12-28-13-15-29(16-14-28)20-8-5-18(25)6-9-20/h5-10,17H,2-4,11-16H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.81n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376331
PNG
(CHEMBL408426)
Show SMILES Fc1ccc(cc1)N1CCN(CCCCC2C(=O)Nc3ccc(F)cc23)CC1
Show InChI InChI=1S/C22H25F2N3O/c23-16-4-7-18(8-5-16)27-13-11-26(12-14-27)10-2-1-3-19-20-15-17(24)6-9-21(20)25-22(19)28/h4-9,15,19H,1-3,10-14H2,(H,25,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.40n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354513
PNG
(CHEMBL269083)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2ccc(Cl)cc12
Show InChI InChI=1S/C24H29Cl2N3O/c1-2-24(21-17-19(26)7-10-22(21)27-23(24)30)11-3-4-12-28-13-15-29(16-14-28)20-8-5-18(25)6-9-20/h5-10,17H,2-4,11-16H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.72n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376326
PNG
(CHEMBL410128)
Show SMILES CCC1(CCCCN2CCc3sccc3C2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C21H26N2OS/c1-2-21(17-7-3-4-8-18(17)22-20(21)24)11-5-6-12-23-13-9-19-16(15-23)10-14-25-19/h3-4,7-8,10,14H,2,5-6,9,11-13,15H2,1H3,(H,22,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.31n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376337
PNG
(CHEMBL259215)
Show SMILES CCC1(CCCCN2CCN(CC2)c2cccc(Cl)c2)C(=O)Nc2c1cc(F)cc2Cl
Show InChI InChI=1S/C24H28Cl2FN3O/c1-2-24(20-15-18(27)16-21(26)22(20)28-23(24)31)8-3-4-9-29-10-12-30(13-11-29)19-7-5-6-17(25)14-19/h5-7,14-16H,2-4,8-13H2,1H3,(H,28,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.75n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354523
PNG
(CHEMBL407412)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccccc2Cl)C(=O)Nc2ccccc12
Show InChI InChI=1S/C24H30ClN3O/c1-2-24(19-9-3-5-11-21(19)26-23(24)29)13-7-8-14-27-15-17-28(18-16-27)22-12-6-4-10-20(22)25/h3-6,9-12H,2,7-8,13-18H2,1H3,(H,26,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.11n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354496
PNG
(CHEMBL258537)
Show SMILES CCC1(CCCCN2CCC(CC2)c2ccc(F)cc2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C25H31FN2O/c1-2-25(22-7-3-4-8-23(22)27-24(25)29)15-5-6-16-28-17-13-20(14-18-28)19-9-11-21(26)12-10-19/h3-4,7-12,20H,2,5-6,13-18H2,1H3,(H,27,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.30n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354524
PNG
(CHEMBL265927)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccccc2OC)C(=O)Nc2ccccc12
Show InChI InChI=1S/C25H33N3O2/c1-3-25(20-10-4-5-11-21(20)26-24(25)29)14-8-9-15-27-16-18-28(19-17-27)22-12-6-7-13-23(22)30-2/h4-7,10-13H,3,8-9,14-19H2,1-2H3,(H,26,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.38n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376322
PNG
(CHEMBL260761)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2c1cc(F)cc2Cl
Show InChI InChI=1S/C24H28Cl2FN3O/c1-2-24(20-15-18(27)16-21(26)22(20)28-23(24)31)9-3-4-10-29-11-13-30(14-12-29)19-7-5-17(25)6-8-19/h5-8,15-16H,2-4,9-14H2,1H3,(H,28,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.97n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376334
PNG
(CHEMBL408451)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccccc2OC)C(=O)N(Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C32H39N3O2/c1-3-32(27-15-7-8-16-28(27)35(31(32)36)25-26-13-5-4-6-14-26)19-11-12-20-33-21-23-34(24-22-33)29-17-9-10-18-30(29)37-2/h4-10,13-18H,3,11-12,19-25H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.57n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354512
PNG
(CHEMBL260551)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2cc(F)c(Cl)cc12
Show InChI InChI=1S/C24H28Cl2FN3O/c1-2-24(19-15-20(26)21(27)16-22(19)28-23(24)31)9-3-4-10-29-11-13-30(14-12-29)18-7-5-17(25)6-8-18/h5-8,15-16H,2-4,9-14H2,1H3,(H,28,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.99n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376325
PNG
(CHEMBL407263)
Show SMILES CCC1(CCCCN2CCc3ccccc3C2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C23H28N2O/c1-2-23(20-11-5-6-12-21(20)24-22(23)26)14-7-8-15-25-16-13-18-9-3-4-10-19(18)17-25/h3-6,9-12H,2,7-8,13-17H2,1H3,(H,24,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
7.65n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376338
PNG
(CHEMBL411919)
Show SMILES CCC1(CCCCN2CCN(CC2)c2cccc(Cl)c2)C(=O)Nc2ccc(Cl)cc12
Show InChI InChI=1S/C24H29Cl2N3O/c1-2-24(21-17-19(26)8-9-22(21)27-23(24)30)10-3-4-11-28-12-14-29(15-13-28)20-7-5-6-18(25)16-20/h5-9,16-17H,2-4,10-15H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
8.27n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354519
PNG
(CHEMBL261009)
Show SMILES CCC1(CCCCN2CCN(CC2)c2cccc(Cl)c2)C(=O)Nc2cc(F)c(Cl)cc12
Show InChI InChI=1S/C24H28Cl2FN3O/c1-2-24(19-15-20(26)21(27)16-22(19)28-23(24)31)8-3-4-9-29-10-12-30(13-11-29)18-7-5-6-17(25)14-18/h5-7,14-16H,2-4,8-13H2,1H3,(H,28,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
9.07n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376323
PNG
(CHEMBL259009)
Show SMILES CCC1(CCCCN2CCN(CC2)c2cccc(Cl)c2)C(=O)Nc2c1cc(Cl)cc2Cl
Show InChI InChI=1S/C24H28Cl3N3O/c1-2-24(20-15-18(26)16-21(27)22(20)28-23(24)31)8-3-4-9-29-10-12-30(13-11-29)19-7-5-6-17(25)14-19/h5-7,14-16H,2-4,8-13H2,1H3,(H,28,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
9.46n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354511
PNG
(CHEMBL260870)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2c1cc(Cl)cc2Cl
Show InChI InChI=1S/C24H28Cl3N3O/c1-2-24(20-15-18(26)16-21(27)22(20)28-23(24)31)9-3-4-10-29-11-13-30(14-12-29)19-7-5-17(25)6-8-19/h5-8,15-16H,2-4,9-14H2,1H3,(H,28,31)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
10.1n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50354492
PNG
(CHEMBL260994)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCC2C(=O)Nc3ccccc23)CC1
Show InChI InChI=1S/C22H26ClN3O/c23-17-8-10-18(11-9-17)26-15-13-25(14-16-26)12-4-3-6-20-19-5-1-2-7-21(19)24-22(20)27/h1-2,5,7-11,20H,3-4,6,12-16H2,(H,24,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
17.5n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Inhibition of 5HT2A receptor


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50354493
PNG
(CHEMBL409662)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2cc(F)ccc12
Show InChI InChI=1S/C24H29ClFN3O/c1-2-24(21-10-7-19(26)17-22(21)27-23(24)30)11-3-4-12-28-13-15-29(16-14-28)20-8-5-18(25)6-9-20/h5-10,17H,2-4,11-16H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
19.4n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Inhibition of 5HT2A receptor


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))
BDBM50354525
PNG
(CHEMBL411663)
Show SMILES Fc1ccc2NC(=O)C(CCCCN3CCN(CC3)c3ccccc3)c2c1
Show InChI InChI=1S/C22H26FN3O/c23-17-9-10-21-20(16-17)19(22(27)24-21)8-4-5-11-25-12-14-26(15-13-25)18-6-2-1-3-7-18/h1-3,6-7,9-10,16,19H,4-5,8,11-15H2,(H,24,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
20n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Inhibition of adrenergic alpha-1 receptor


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376321
PNG
(CHEMBL412143)
Show SMILES CCC1(CCCN2CCN(CC2)c2cccc(Cl)c2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C23H28ClN3O/c1-2-23(20-9-3-4-10-21(20)25-22(23)28)11-6-12-26-13-15-27(16-14-26)19-8-5-7-18(24)17-19/h3-5,7-10,17H,2,6,11-16H2,1H3,(H,25,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
21n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376329
PNG
(CHEMBL258593)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(OC)cc2)C(=O)Nc2ccccc12
Show InChI InChI=1S/C25H33N3O2/c1-3-25(22-8-4-5-9-23(22)26-24(25)29)14-6-7-15-27-16-18-28(19-17-27)20-10-12-21(30-2)13-11-20/h4-5,8-13H,3,6-7,14-19H2,1-2H3,(H,26,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
25.4n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50376341
PNG
(CHEMBL408429)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccccc2)C(=O)N(C)c2ccccc12
Show InChI InChI=1S/C25H33N3O/c1-3-25(22-13-7-8-14-23(22)26(2)24(25)29)15-9-10-16-27-17-19-28(20-18-27)21-11-5-4-6-12-21/h4-8,11-14H,3,9-10,15-20H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
33.4n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))
BDBM50354492
PNG
(CHEMBL260994)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCC2C(=O)Nc3ccccc23)CC1
Show InChI InChI=1S/C22H26ClN3O/c23-17-8-10-18(11-9-17)26-15-13-25(14-16-26)12-4-3-6-20-19-5-1-2-7-21(19)24-22(20)27/h1-2,5,7-11,20H,3-4,6,12-16H2,(H,24,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
42n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Inhibition of adrenergic alpha-1 receptor


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (human))
BDBM50354525
PNG
(CHEMBL411663)
Show SMILES Fc1ccc2NC(=O)C(CCCCN3CCN(CC3)c3ccccc3)c2c1
Show InChI InChI=1S/C22H26FN3O/c23-17-9-10-21-20(16-17)19(22(27)24-21)8-4-5-11-25-12-14-26(15-13-25)18-6-2-1-3-7-18/h1-3,6-7,9-10,16,19H,4-5,8,11-15H2,(H,24,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
44n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50354525
PNG
(CHEMBL411663)
Show SMILES Fc1ccc2NC(=O)C(CCCCN3CCN(CC3)c3ccccc3)c2c1
Show InChI InChI=1S/C22H26FN3O/c23-17-9-10-21-20(16-17)19(22(27)24-21)8-4-5-11-25-12-14-26(15-13-25)18-6-2-1-3-7-18/h1-3,6-7,9-10,16,19H,4-5,8,11-15H2,(H,24,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
55n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Inhibition of 5HT2A receptor


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))
BDBM50354493
PNG
(CHEMBL409662)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2cc(F)ccc12
Show InChI InChI=1S/C24H29ClFN3O/c1-2-24(21-10-7-19(26)17-22(21)27-23(24)30)11-3-4-12-28-13-15-29(16-14-28)20-8-5-18(25)6-9-20/h5-10,17H,2-4,11-16H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
71.3n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Inhibition of adrenergic alpha-1 receptor


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50354525
PNG
(CHEMBL411663)
Show SMILES Fc1ccc2NC(=O)C(CCCCN3CCN(CC3)c3ccccc3)c2c1
Show InChI InChI=1S/C22H26FN3O/c23-17-9-10-21-20(16-17)19(22(27)24-21)8-4-5-11-25-12-14-26(15-13-25)18-6-2-1-3-7-18/h1-3,6-7,9-10,16,19H,4-5,8,11-15H2,(H,24,27)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
150n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Inhibition of 5HT1A receptor in rat frontal cortex membrane


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (human))
BDBM50354493
PNG
(CHEMBL409662)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2cc(F)ccc12
Show InChI InChI=1S/C24H29ClFN3O/c1-2-24(21-10-7-19(26)17-22(21)27-23(24)30)11-3-4-12-28-13-15-29(16-14-28)20-8-5-18(25)6-9-20/h5-10,17H,2-4,11-16H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
187n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Inhibition of 5HT6 receptor


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50354525
PNG
(CHEMBL411663)
Show SMILES Fc1ccc2NC(=O)C(CCCCN3CCN(CC3)c3ccccc3)c2c1
Show InChI InChI=1S/C22H26FN3O/c23-17-9-10-21-20(16-17)19(22(27)24-21)8-4-5-11-25-12-14-26(15-13-25)18-6-2-1-3-7-18/h1-3,6-7,9-10,16,19H,4-5,8,11-15H2,(H,24,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
330n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Inhibition of dopamine D2 receptor


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C)


(Homo sapiens (human))
BDBM50354493
PNG
(CHEMBL409662)
Show SMILES CCC1(CCCCN2CCN(CC2)c2ccc(Cl)cc2)C(=O)Nc2cc(F)ccc12
Show InChI InChI=1S/C24H29ClFN3O/c1-2-24(21-10-7-19(26)17-22(21)27-23(24)30)11-3-4-12-28-13-15-29(16-14-28)20-8-5-18(25)6-9-20/h5-10,17H,2-4,11-16H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
358n/an/an/an/an/an/an/an/a



EGIS Pharmaceuticals Plc

Curated by ChEMBL


Assay Description
Inhibition of 5HT2C receptor


J Med Chem 51: 2522-32 (2008)


Article DOI: 10.1021/jm070279v
BindingDB Entry DOI: 10.7270/Q2QF8TQ0
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 61 total )  |  Next  |  Last  >>
Jump to: