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Compile Data Set for Download or QSAR

Found 7 hits from Eisai Co., Ltd.   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50120465
PNG
(CHEMBL281995 | N-(2-Chloro-1H-indol-7-yl)-4-methox...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1cccc2cc(Cl)[nH]c12
Show InChI InChI=1S/C15H13ClN2O3S/c1-21-11-5-7-12(8-6-11)22(19,20)18-13-4-2-3-10-9-14(16)17-15(10)13/h2-9,17-18H,1H3
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Eisai Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against tubulin polymerization.


J Med Chem 45: 4913-22 (2002)

More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50101086
PNG
(CHEMBL20684 | E-7010 | N-(2-(4-hydroxyphenylamino)...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1cccnc1Nc1ccc(O)cc1
Show InChI InChI=1S/C18H17N3O4S/c1-25-15-8-10-16(11-9-15)26(23,24)21-17-3-2-12-19-18(17)20-13-4-6-14(22)7-5-13/h2-12,21-22H,1H3,(H,19,20)
UniProtKB/TrEMBL

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CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents

PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



Eisai Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against tubulin polymerization.


J Med Chem 45: 4913-22 (2002)

More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50120462
PNG
(CHEMBL20289 | N-(3-Chloro-1H-indol-7-yl)-4-methoxy...)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12
Show InChI InChI=1S/C15H13ClN2O3S/c1-21-10-5-7-11(8-6-10)22(19,20)18-14-4-2-3-12-13(16)9-17-15(12)14/h2-9,17-18H,1H3
UniProtKB/TrEMBL

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 9.50E+3n/an/an/an/an/an/a



Eisai Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against tubulin polymerization.


J Med Chem 45: 4913-22 (2002)

More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50473976
PNG
(CHEMBL358114)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)Nc1cccc2c(Cl)c[nH]c12
Show InChI InChI=1S/C15H12ClN3O3S/c16-12-8-18-14-11(12)2-1-3-13(14)19-15(20)9-4-6-10(7-5-9)23(17,21)22/h1-8,18H,(H,19,20)(H2,17,21,22)
UniProtKB/TrEMBL

GoogleScholar
UniChem
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Eisai Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against tubulin polymerization.


J Med Chem 45: 4913-22 (2002)

More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM10890
PNG
(1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonam...)
Show SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12
Show InChI InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20)
UniProtKB/TrEMBL

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Eisai Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against tubulin polymerization.


J Med Chem 45: 4913-22 (2002)

More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50473974
PNG
(CHEMBL146194)
Show SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2cc[nH]c12
Show InChI InChI=1S/C14H13N3O4S2/c15-22(18,19)11-4-6-12(7-5-11)23(20,21)17-13-3-1-2-10-8-9-16-14(10)13/h1-9,16-17H,(H2,15,18,19)
UniProtKB/TrEMBL

GoogleScholar
UniChem
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Eisai Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against tubulin polymerization.


J Med Chem 45: 4913-22 (2002)

More data for this
Ligand-Target Pair
Similar to alpha-tubulin isoform 1


(Bos taurus)
BDBM50473975
PNG
(CHEMBL20814)
Show SMILES Clc1c[nH]c2c(NS(=O)(=O)c3ccc(cc3)C#N)cccc12
Show InChI InChI=1S/C15H10ClN3O2S/c16-13-9-18-15-12(13)2-1-3-14(15)19-22(20,21)11-6-4-10(8-17)5-7-11/h1-7,9,18-19H
UniProtKB/TrEMBL

GoogleScholar
UniChem
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Eisai Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against tubulin polymerization.


J Med Chem 45: 4913-22 (2002)

More data for this
Ligand-Target Pair