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Compile Data Set for Download or QSAR

Found 88 hits from Emory University   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50436073
PNG
(CHEMBL2397210)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(c2)-c2ccccc2)cc1
Show InChI InChI=1S/C32H31NO5/c1-35-26-12-14-27(15-13-26)38-21-29-28-20-31(37-3)30(36-2)19-24(28)16-17-33(29)32(34)25-11-7-10-23(18-25)22-8-5-4-6-9-22/h4-15,18-20,29H,16-17,21H2,1-3H3
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n/an/an/an/a 2.90E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50436074
PNG
(CHEMBL2397209)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(I)c2)cc1
Show InChI InChI=1S/C26H26INO5/c1-30-20-7-9-21(10-8-20)33-16-23-22-15-25(32-3)24(31-2)14-17(22)11-12-28(23)26(29)18-5-4-6-19(27)13-18/h4-10,13-15,23H,11-12,16H2,1-3H3
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n/an/an/an/a 4.00E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50436075
PNG
(CHEMBL2397208)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(F)c2)cc1
Show InChI InChI=1S/C26H26FNO5/c1-30-20-7-9-21(10-8-20)33-16-23-22-15-25(32-3)24(31-2)14-17(22)11-12-28(23)26(29)18-5-4-6-19(27)13-18/h4-10,13-15,23H,11-12,16H2,1-3H3
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n/an/an/an/a 7.20E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50436076
PNG
(CHEMBL2397124)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2ccc(F)c(Cl)c2)cc1
Show InChI InChI=1S/C26H25ClFNO5/c1-31-18-5-7-19(8-6-18)34-15-23-20-14-25(33-3)24(32-2)13-16(20)10-11-29(23)26(30)17-4-9-22(28)21(27)12-17/h4-9,12-14,23H,10-11,15H2,1-3H3
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n/an/an/an/a 5.30E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50436077
PNG
(CHEMBL2397123)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cc(Cl)cc(Cl)c2)cc1
Show InChI InChI=1S/C26H25Cl2NO5/c1-31-20-4-6-21(7-5-20)34-15-23-22-14-25(33-3)24(32-2)12-16(22)8-9-29(23)26(30)17-10-18(27)13-19(28)11-17/h4-7,10-14,23H,8-9,15H2,1-3H3
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n/an/an/an/a 4.80E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50436078
PNG
(CHEMBL2397109)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(Cl)c2Cl)cc1
Show InChI InChI=1S/C26H25Cl2NO5/c1-31-17-7-9-18(10-8-17)34-15-22-20-14-24(33-3)23(32-2)13-16(20)11-12-29(22)26(30)19-5-4-6-21(27)25(19)28/h4-10,13-14,22H,11-12,15H2,1-3H3
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n/an/an/an/a 1.40E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50436079
PNG
(CHEMBL2397108)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2ccc(Cl)c(Cl)c2)cc1
Show InChI InChI=1S/C26H25Cl2NO5/c1-31-18-5-7-19(8-6-18)34-15-23-20-14-25(33-3)24(32-2)13-16(20)10-11-29(23)26(30)17-4-9-21(27)22(28)12-17/h4-9,12-14,23H,10-11,15H2,1-3H3
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n/an/an/an/a 2.10E+4n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50436080
PNG
(CHEMBL2397107)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(c2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C26H26N2O7/c1-32-20-7-9-21(10-8-20)35-16-23-22-15-25(34-3)24(33-2)14-17(22)11-12-27(23)26(29)18-5-4-6-19(13-18)28(30)31/h4-10,13-15,23H,11-12,16H2,1-3H3
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n/an/an/an/a 1.10E+4n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50436081
PNG
(CHEMBL2397105)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(OC)c2)cc1
Show InChI InChI=1S/C27H29NO6/c1-30-20-8-10-21(11-9-20)34-17-24-23-16-26(33-4)25(32-3)15-18(23)12-13-28(24)27(29)19-6-5-7-22(14-19)31-2/h5-11,14-16,24H,12-13,17H2,1-4H3
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n/an/an/an/a 5.80E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50436082
PNG
(CHEMBL2397103)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(Br)c2)cc1
Show InChI InChI=1S/C26H26BrNO5/c1-30-20-7-9-21(10-8-20)33-16-23-22-15-25(32-3)24(31-2)14-17(22)11-12-28(23)26(29)18-5-4-6-19(27)13-18/h4-10,13-15,23H,11-12,16H2,1-3H3
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n/an/an/an/a 900n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50436083
PNG
(CHEMBL2397097)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(C)c2)cc1
Show InChI InChI=1S/C27H29NO5/c1-18-6-5-7-20(14-18)27(29)28-13-12-19-15-25(31-3)26(32-4)16-23(19)24(28)17-33-22-10-8-21(30-2)9-11-22/h5-11,14-16,24H,12-13,17H2,1-4H3
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n/an/an/an/a 6.20E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1


(RAT-Rattus norvegicus (Rat))
BDBM50436084
PNG
(CHEMBL2397095)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2ccccc2)cc1
Show InChI InChI=1S/C26H27NO5/c1-29-20-9-11-21(12-10-20)32-17-23-22-16-25(31-3)24(30-2)15-19(22)13-14-27(23)26(28)18-7-5-4-6-8-18/h4-12,15-16,23H,13-14,17H2,1-3H3
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n/an/an/an/a 1.20E+4n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436085
PNG
(CHEMBL2397093)
Show SMILES COc1ccc(OC[C@H]2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(Cl)c2)cc1
Show InChI InChI=1S/C26H26ClNO5/c1-30-20-7-9-21(10-8-20)33-16-23-22-15-25(32-3)24(31-2)14-17(22)11-12-28(23)26(29)18-5-4-6-19(27)13-18/h4-10,13-15,23H,11-12,16H2,1-3H3/t23-/m1/s1
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n/an/an/an/a 8.00E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436086
PNG
(CHEMBL2397272)
Show SMILES COc1ccc(CCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(Br)c2)cc1
Show InChI InChI=1S/C27H28BrNO4/c1-31-22-10-7-18(8-11-22)9-12-24-23-17-26(33-3)25(32-2)16-19(23)13-14-29(24)27(30)20-5-4-6-21(28)15-20/h4-8,10-11,15-17,24H,9,12-14H2,1-3H3
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n/an/an/an/a 1.50E+4n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436087
PNG
(CHEMBL2397274)
Show SMILES COc1ccc(\C=C\C2N(CCc3cc(OC)ccc23)C(=O)c2cccc(Br)c2)cc1
Show InChI InChI=1S/C26H24BrNO3/c1-30-22-9-6-18(7-10-22)8-13-25-24-12-11-23(31-2)17-19(24)14-15-28(25)26(29)20-4-3-5-21(27)16-20/h3-13,16-17,25H,14-15H2,1-2H3/b13-8+
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n/an/an/an/a 1.70E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436088
PNG
(CHEMBL2397121)
Show SMILES COc1ccc(\C=C\C2N(CCc3cc(OC)ccc23)C(=O)c2cccc(Cl)c2)cc1
Show InChI InChI=1S/C26H24ClNO3/c1-30-22-9-6-18(7-10-22)8-13-25-24-12-11-23(31-2)17-19(24)14-15-28(25)26(29)20-4-3-5-21(27)16-20/h3-13,16-17,25H,14-15H2,1-2H3/b13-8+
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n/an/an/an/a 1.00E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436089
PNG
(CHEMBL2397120)
Show SMILES COc1ccc(\C=C\C2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(Br)c2)cc1
Show InChI InChI=1S/C27H26BrNO4/c1-31-22-10-7-18(8-11-22)9-12-24-23-17-26(33-3)25(32-2)16-19(23)13-14-29(24)27(30)20-5-4-6-21(28)15-20/h4-12,15-17,24H,13-14H2,1-3H3/b12-9+
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n/an/an/an/a 2.80E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436090
PNG
(CHEMBL2397119)
Show SMILES COc1ccc(\C=C\C2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(Cl)c2)cc1
Show InChI InChI=1S/C27H26ClNO4/c1-31-22-10-7-18(8-11-22)9-12-24-23-17-26(33-3)25(32-2)16-19(23)13-14-29(24)27(30)20-5-4-6-21(28)15-20/h4-12,15-17,24H,13-14H2,1-3H3/b12-9+
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n/an/an/an/a 1.30E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436091
PNG
(CHEMBL2397118)
Show SMILES COc1ccc(\C=C\C2N(CCc3cc(OC)c(OC)cc23)C(=O)c2ccccc2)cc1
Show InChI InChI=1S/C27H27NO4/c1-30-22-12-9-19(10-13-22)11-14-24-23-18-26(32-3)25(31-2)17-21(23)15-16-28(24)27(29)20-7-5-4-6-8-20/h4-14,17-18,24H,15-16H2,1-3H3/b14-11+
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n/an/an/an/a 3.50E+4n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436092
PNG
(CHEMBL2397113)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=S)Nc2cccc(C)c2)cc1
Show InChI InChI=1S/C27H30N2O4S/c1-18-6-5-7-20(14-18)28-27(34)29-13-12-19-15-25(31-3)26(32-4)16-23(19)24(29)17-33-22-10-8-21(30-2)9-11-22/h5-11,14-16,24H,12-13,17H2,1-4H3,(H,28,34)
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n/an/an/an/a 4.90E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436093
PNG
(CHEMBL2397268)
Show SMILES COc1ccc(OCC2N(CCc3cc(OCc4ccccc4)ccc23)C(=O)c2cccc(Br)c2)cc1
Show InChI InChI=1S/C31H28BrNO4/c1-35-26-10-12-27(13-11-26)37-21-30-29-15-14-28(36-20-22-6-3-2-4-7-22)19-23(29)16-17-33(30)31(34)24-8-5-9-25(32)18-24/h2-15,18-19,30H,16-17,20-21H2,1H3
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n/an/an/an/a 300n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436094
PNG
(CHEMBL2397267)
Show SMILES COc1ccc(OCC2N(CCc3cc(OCc4ccccc4)ccc23)C(=O)c2cccc(Cl)c2)cc1
Show InChI InChI=1S/C31H28ClNO4/c1-35-26-10-12-27(13-11-26)37-21-30-29-15-14-28(36-20-22-6-3-2-4-7-22)19-23(29)16-17-33(30)31(34)24-8-5-9-25(32)18-24/h2-15,18-19,30H,16-17,20-21H2,1H3
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n/an/an/an/a 400n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436095
PNG
(CHEMBL2397266)
Show SMILES COc1ccc(OCC2N(CCc3cc(OCc4ccccc4)ccc23)C(=O)c2ccccc2)cc1
Show InChI InChI=1S/C31H29NO4/c1-34-26-12-14-27(15-13-26)36-22-30-29-17-16-28(35-21-23-8-4-2-5-9-23)20-25(29)18-19-32(30)31(33)24-10-6-3-7-11-24/h2-17,20,30H,18-19,21-22H2,1H3
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n/an/an/an/a 2.30E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436096
PNG
(CHEMBL2397265)
Show SMILES COc1ccc(OCC2N(CCc3cc(C)ccc23)C(=O)c2cccc(Br)c2)cc1
Show InChI InChI=1S/C25H24BrNO3/c1-17-6-11-23-18(14-17)12-13-27(25(28)19-4-3-5-20(26)15-19)24(23)16-30-22-9-7-21(29-2)8-10-22/h3-11,14-15,24H,12-13,16H2,1-2H3
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n/an/an/an/a 3.60E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436097
PNG
(CHEMBL2397264)
Show SMILES COc1ccc(OCC2N(CCc3cc(C)ccc23)C(=O)c2cccc(Cl)c2)cc1
Show InChI InChI=1S/C25H24ClNO3/c1-17-6-11-23-18(14-17)12-13-27(25(28)19-4-3-5-20(26)15-19)24(23)16-30-22-9-7-21(29-2)8-10-22/h3-11,14-15,24H,12-13,16H2,1-2H3
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n/an/an/an/a 4.70E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436098
PNG
(CHEMBL2397262)
Show SMILES COc1ccc(OCC2N(CCc3cc(C)c(C)cc23)C(=O)c2cccc(Br)c2)cc1
Show InChI InChI=1S/C26H26BrNO3/c1-17-13-19-11-12-28(26(29)20-5-4-6-21(27)15-20)25(24(19)14-18(17)2)16-31-23-9-7-22(30-3)8-10-23/h4-10,13-15,25H,11-12,16H2,1-3H3
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n/an/an/an/a 1.10E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436099
PNG
(CHEMBL2397261)
Show SMILES COc1ccc(OCC2N(CCc3cc(C)c(C)cc23)C(=O)c2cccc(Cl)c2)cc1
Show InChI InChI=1S/C26H26ClNO3/c1-17-13-19-11-12-28(26(29)20-5-4-6-21(27)15-20)25(24(19)14-18(17)2)16-31-23-9-7-22(30-3)8-10-23/h4-10,13-15,25H,11-12,16H2,1-3H3
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n/an/an/an/a 1.50E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436100
PNG
(CHEMBL2397258)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)ccc23)C(=O)c2cccc(c2)C(C)=O)cc1
Show InChI InChI=1S/C27H27NO5/c1-18(29)19-5-4-6-21(15-19)27(30)28-14-13-20-16-24(32-3)11-12-25(20)26(28)17-33-23-9-7-22(31-2)8-10-23/h4-12,15-16,26H,13-14,17H2,1-3H3
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n/an/an/an/a 3.20E+4n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436101
PNG
(CHEMBL2397257)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)ccc23)C(=O)c2cccc(Br)c2)cc1
Show InChI InChI=1S/C25H24BrNO4/c1-29-20-6-8-21(9-7-20)31-16-24-23-11-10-22(30-2)15-17(23)12-13-27(24)25(28)18-4-3-5-19(26)14-18/h3-11,14-15,24H,12-13,16H2,1-2H3
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n/an/an/an/a 2.90E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436102
PNG
(CHEMBL2397256)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)ccc23)C(=O)c2cccc(Cl)c2)cc1
Show InChI InChI=1S/C25H24ClNO4/c1-29-20-6-8-21(9-7-20)31-16-24-23-11-10-22(30-2)15-17(23)12-13-27(24)25(28)18-4-3-5-19(26)14-18/h3-11,14-15,24H,12-13,16H2,1-2H3
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n/an/an/an/a 1.00E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436103
PNG
(CHEMBL2397255)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)ccc23)C(=O)c2ccccc2)cc1
Show InChI InChI=1S/C25H25NO4/c1-28-20-8-10-21(11-9-20)30-17-24-23-13-12-22(29-2)16-19(23)14-15-26(24)25(27)18-6-4-3-5-7-18/h3-13,16,24H,14-15,17H2,1-2H3
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n/an/an/an/a 5.70E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436104
PNG
(CHEMBL2397254)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)cc(OC)c23)C(=O)c2cccc(Br)c2)cc1
Show InChI InChI=1S/C26H26BrNO5/c1-30-20-7-9-21(10-8-20)33-16-23-25-17(14-22(31-2)15-24(25)32-3)11-12-28(23)26(29)18-5-4-6-19(27)13-18/h4-10,13-15,23H,11-12,16H2,1-3H3
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n/an/an/an/a 7.80E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436105
PNG
(CHEMBL2397253)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)cc(OC)c23)C(=O)c2cccc(Cl)c2)cc1
Show InChI InChI=1S/C26H26ClNO5/c1-30-20-7-9-21(10-8-20)33-16-23-25-17(14-22(31-2)15-24(25)32-3)11-12-28(23)26(29)18-5-4-6-19(27)13-18/h4-10,13-15,23H,11-12,16H2,1-3H3
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n/an/an/an/a 9.20E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436062
PNG
(CHEMBL2397252)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)cc(OC)c23)C(=O)c2ccccc2)cc1
Show InChI InChI=1S/C26H27NO5/c1-29-20-9-11-21(12-10-20)32-17-23-25-19(15-22(30-2)16-24(25)31-3)13-14-27(23)26(28)18-7-5-4-6-8-18/h4-12,15-16,23H,13-14,17H2,1-3H3
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n/an/an/an/a 1.40E+4n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436063
PNG
(CHEMBL2397251)
Show SMILES COc1ccc(OCC2N(CCc3cc4OCOc4cc23)C(=O)c2cccc(Br)c2)cc1
Show InChI InChI=1S/C25H22BrNO5/c1-29-19-5-7-20(8-6-19)30-14-22-21-13-24-23(31-15-32-24)12-16(21)9-10-27(22)25(28)17-3-2-4-18(26)11-17/h2-8,11-13,22H,9-10,14-15H2,1H3
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n/an/an/an/a 3.40E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436064
PNG
(CHEMBL2397250)
Show SMILES COc1ccc(OCC2N(CCc3cc4OCOc4cc23)C(=O)c2cccc(Cl)c2)cc1
Show InChI InChI=1S/C25H22ClNO5/c1-29-19-5-7-20(8-6-19)30-14-22-21-13-24-23(31-15-32-24)12-16(21)9-10-27(22)25(28)17-3-2-4-18(26)11-17/h2-8,11-13,22H,9-10,14-15H2,1H3
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n/an/an/an/a 7.40E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436068
PNG
(CHEMBL2397232)
Show SMILES COc1cc2CCN(C(COc3ccc(SC)cc3)c2cc1OC)C(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C26H26ClNO4S/c1-30-24-14-17-11-12-28(26(29)18-5-4-6-19(27)13-18)23(22(17)15-25(24)31-2)16-32-20-7-9-21(33-3)10-8-20/h4-10,13-15,23H,11-12,16H2,1-3H3
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n/an/an/an/a 5.30E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436070
PNG
(CHEMBL2397215)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(c2)C#N)cc1
Show InChI InChI=1S/C27H26N2O5/c1-31-21-7-9-22(10-8-21)34-17-24-23-15-26(33-3)25(32-2)14-19(23)11-12-29(24)27(30)20-6-4-5-18(13-20)16-28/h4-10,13-15,24H,11-12,17H2,1-3H3
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n/an/an/an/a 7.70E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436071
PNG
(CHEMBL2397214)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(c2)C(Cl)Cl)cc1
Show InChI InChI=1S/C27H27Cl2NO5/c1-32-20-7-9-21(10-8-20)35-16-23-22-15-25(34-3)24(33-2)14-17(22)11-12-30(23)27(31)19-6-4-5-18(13-19)26(28)29/h4-10,13-15,23,26H,11-12,16H2,1-3H3
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n/an/an/an/a 5.40E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436072
PNG
(CHEMBL2397211)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(c2)C(F)(F)F)cc1
Show InChI InChI=1S/C27H26F3NO5/c1-33-20-7-9-21(10-8-20)36-16-23-22-15-25(35-3)24(34-2)14-17(22)11-12-31(23)26(32)18-5-4-6-19(13-18)27(28,29)30/h4-10,13-15,23H,11-12,16H2,1-3H3
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n/an/an/an/a 2.40E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436073
PNG
(CHEMBL2397210)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(c2)-c2ccccc2)cc1
Show InChI InChI=1S/C32H31NO5/c1-35-26-12-14-27(15-13-26)38-21-29-28-20-31(37-3)30(36-2)19-24(28)16-17-33(29)32(34)25-11-7-10-23(18-25)22-8-5-4-6-9-22/h4-15,18-20,29H,16-17,21H2,1-3H3
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n/an/an/an/a 3.60E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436074
PNG
(CHEMBL2397209)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(I)c2)cc1
Show InChI InChI=1S/C26H26INO5/c1-30-20-7-9-21(10-8-20)33-16-23-22-15-25(32-3)24(31-2)14-17(22)11-12-28(23)26(29)18-5-4-6-19(27)13-18/h4-10,13-15,23H,11-12,16H2,1-3H3
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n/an/an/an/a 4.90E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436075
PNG
(CHEMBL2397208)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(F)c2)cc1
Show InChI InChI=1S/C26H26FNO5/c1-30-20-7-9-21(10-8-20)33-16-23-22-15-25(32-3)24(31-2)14-17(22)11-12-28(23)26(29)18-5-4-6-19(27)13-18/h4-10,13-15,23H,11-12,16H2,1-3H3
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n/an/an/an/a 7.00E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436076
PNG
(CHEMBL2397124)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2ccc(F)c(Cl)c2)cc1
Show InChI InChI=1S/C26H25ClFNO5/c1-31-18-5-7-19(8-6-18)34-15-23-20-14-25(33-3)24(32-2)13-16(20)10-11-29(23)26(30)17-4-9-22(28)21(27)12-17/h4-9,12-14,23H,10-11,15H2,1-3H3
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n/an/an/an/a 5.30E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436077
PNG
(CHEMBL2397123)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cc(Cl)cc(Cl)c2)cc1
Show InChI InChI=1S/C26H25Cl2NO5/c1-31-20-4-6-21(7-5-20)34-15-23-22-14-25(33-3)24(32-2)12-16(22)8-9-29(23)26(30)17-10-18(27)13-19(28)11-17/h4-7,10-14,23H,8-9,15H2,1-3H3
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n/an/an/an/a 1.90E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436079
PNG
(CHEMBL2397108)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2ccc(Cl)c(Cl)c2)cc1
Show InChI InChI=1S/C26H25Cl2NO5/c1-31-18-5-7-19(8-6-18)34-15-23-20-14-25(33-3)24(32-2)13-16(20)10-11-29(23)26(30)17-4-9-21(27)22(28)12-17/h4-9,12-14,23H,10-11,15H2,1-3H3
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n/an/an/an/a 2.40E+4n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436080
PNG
(CHEMBL2397107)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(c2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C26H26N2O7/c1-32-20-7-9-21(10-8-20)35-16-23-22-15-25(34-3)24(33-2)14-17(22)11-12-27(23)26(29)18-5-4-6-19(13-18)28(30)31/h4-10,13-15,23H,11-12,16H2,1-3H3
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n/an/an/an/a 1.30E+4n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436081
PNG
(CHEMBL2397105)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(OC)c2)cc1
Show InChI InChI=1S/C27H29NO6/c1-30-20-8-10-21(11-9-20)34-17-24-23-16-26(33-4)25(32-3)15-18(23)12-13-28(24)27(29)19-6-5-7-22(14-19)31-2/h5-11,14-16,24H,12-13,17H2,1-4H3
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n/an/an/an/a 1.20E+4n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436082
PNG
(CHEMBL2397103)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(Br)c2)cc1
Show InChI InChI=1S/C26H26BrNO5/c1-30-20-7-9-21(10-8-20)33-16-23-22-15-25(32-3)24(31-2)14-17(22)11-12-28(23)26(29)18-5-4-6-19(27)13-18/h4-10,13-15,23H,11-12,16H2,1-3H3
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n/an/an/an/a 2.20E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50436083
PNG
(CHEMBL2397097)
Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(C)c2)cc1
Show InChI InChI=1S/C27H29NO5/c1-18-6-5-7-20(14-18)27(29)28-13-12-19-15-25(31-3)26(32-4)16-23(19)24(28)17-33-22-10-8-21(30-2)9-11-22/h5-11,14-16,24H,12-13,17H2,1-4H3
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n/an/an/an/a 5.50E+3n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...


J Med Chem 56: 5351-81 (2014)


Article DOI: 10.1021/jm400177t
BindingDB Entry DOI: 10.7270/Q26W9CH4
More data for this
Ligand-Target Pair
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